Abstract：
PURPOSE:Management of anal fistula represents a balance between curing the condition and maintaining anal continence. Recent reports of the results of the porcine anal fistula plug have demonstrated excellent fistula healing rates without reporting significant complications. METHODS:The outcome of patients who underwent treatment for anal fistula with the Surgisis anal plug was retrospectively reviewed. RESULTS:Twenty patients were treated; three underwent concomitant anal advancement flap at the time of plug placement. Seventeen patients had a trans-sphincteric fistula, and three had an anoperineal fistula. Ten patients had previously undergone failed surgical therapy to cure their fistula, including anal advancement flap in four, muscle interposition flap in two, fistulotomy in two, and cutting seton placement in two. Mean follow-up was 7.4 months. Only 4 of 17 (24%) patients treated with the plug alone had closure of their fistula. Acute postoperative sepsis was seen in 5 of 17 (29%) patients treated with the plug alone. Four developed perianal abscesses that required incision and drainage, and one intersphincteric abscess was treated with antibiotics. Two of the patients who underwent concomitant anal advancement flaps and plug placement healed successfully. CONCLUSIONS:Contrary to other published series, the use of the Surgisis anal plug was associated with a low rate of fistula healing and a high incidence of perianal sepsis. The addition of a transanal advancement flap to the procedure may improve success rates.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lawes DA,Efron JE,Abbas M,Heppell J,Young-Fadok TMdoi
10.1007/s00268-008-9504-1subject
Has Abstractpub_date
2008-06-01 00:00:00pages
1157-9issue
6eissn
0364-2313issn
1432-2323journal_volume
32pub_type
杂志文章abstract：:This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' di...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067345
更新日期：1992-07-01 00:00:00
abstract：BACKGROUND:Vibrio vulnificus infection can progress rapidly in skin or soft tissue, and it is potentially life-threatening. The purpose of the present study was to explore the predictors of mortality in patients with V. vulnificus infections of skin or soft tissue. METHODS:The medical records of 119 consecutive patien...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0455-y
更新日期：2010-07-01 00:00:00
abstract：:Carnitine, an important carrier of free fatty acid that is transported into mitochondria for beta-oxidation, was thought to be one of the key factors in the regulation of liver regeneration. If the carnitine content is insufficient in the hepatocyte, it might impair the energy substrate's transport and the energy char...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900347
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:In 2002, the UICC/AJCC TNM classification for papillary thyroid carcinoma was revised. In this study, we examined the validity of this classification system by investigating the predictors of disease-free survival (DFS) and cause-specific survival (CSS) in patients. METHODS:We examined various clinicopathol...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0455-0
更新日期：2007-04-01 00:00:00
abstract：:Reported incidence rates of carcinoma in patients with achalasia and the prevalence of achalasia in patients with esophageal cancer vary widely in the literature. The prognosis of an "achalasia-carcinoma" is generally considered poor, although systematic studies assessing the incidence, prevalence, and prognosis of pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0026-3
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Intra-abdominal adhesions constitute between 49% and 74% of the causes of small bowel obstruction. Traditionally, laparotomy and open adhesiolysis have been the treatment for patients who have failed conservative measures or when clinical and physiologic derangements suggest toxemia and/or ischemia. With the...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7778-0
更新日期：2006-04-01 00:00:00
abstract：INTRODUCTION:Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for op...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4494-0
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Video-assisted thoracoscopic surgery (VATS) is a new area of exploration and evolution in thoracic minimal invasive surgery. The uniportal VATS approach has become popular during lung resection for small nodules and ground glass lesions. Our objective is to investigate the efficacy, availability and safety o...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05781-y
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed recently. Although it seems plausible that SILC will be associated with less pain compared to standard 4-port laparoscopic cholecystectomy (LC), there is currently no conclusive comparative study on the postoperative pain iss...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0842-4
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:Finnmark County is the northernmost county in Norway. For several decades, the rate of mortality after injury in this sparsely inhabited region has remained above the national average. Following documentation of this discrepancy for the period 1991-1995, improvements to the trauma system were implemented. Th...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1102-y
更新日期：2011-07-01 00:00:00
abstract：:Patients with obstructive jaundice (OJ) that requires surgery often have malnutrition associated with increased perioperative morbidity. This study investigated the factors influencing nutritional derangements in these patients. A series of 46 OJ patients were investigated prospectively (28 malignant tumors, 18 benign...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020043
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Postoperative liver failure (PHLF) is one of the most common complications following major hepatectomy. The preoperative assessment of future liver remnant (FLR) function is critical to predict the incidence of PHLF. OBJECTIVE:To determine the efficacy of the plasma clearance rate of indocyanine green clear...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3441-1
更新日期：2016-06-01 00:00:00
abstract：:From January, 1975 to December, 1987, 241 patients with rectal cancer underwent pre-operative irradiation and surgical resection. The radiation was delivered with 25 MeV photons, 5 days per week by 2.4 grays fractions up to a total dose of 36 grays. Surgery was curative in 195 patients; 57% had abdomino-perineal resec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067122
更新日期：1992-01-01 00:00:00
abstract：BACKGROUND:The external branch of the superior laryngeal nerve (EBSLN) is at surgical risk during superior thyroid pole ligation during thyroidectomy. Majority of studies have addressed the identification of these nerves and its reported incidence. Very few studies have addressed the relationship of these nerves with t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3383-z
更新日期：2016-03-01 00:00:00
abstract：:Organ transplantation continues to be hindered by a limited supply of organs. A significant percentage of potential organ donors are lost to either medical failure or inability to obtain consent for donation. In a surgical intensive care unit (ICU) we have refocused our efforts toward aggressive resuscitation, directe...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/pl00012362
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND:The adrenal gland may give rise to pheochromocytomas, which are catecholamine-producing tumors originating from the adrenal medulla, or to adrenocortical tumors, which derive from the adrenocortical cortex and may be secreting or not. The genetic mechanisms underlying the formation of these tumors include so...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0471-5
更新日期：2006-07-01 00:00:00
abstract：BACKGROUND:In patients with negative sentinel lymph node biopsy (SLNB), axillary dissection (AD) can be avoided to reduce morbidities. However, there is only limited data on the rate of positive non-SLN (NSLN) in those who have micrometastasis and isolated tumor cells (ITC) in the literature. METHODS:We did a retrospe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2984-x
更新日期：2015-06-01 00:00:00
abstract：:Recently, surgical services have been gaining greater attention as an integral part of public health in low-income countries due to the significant volume and burden of surgical conditions, growing evidence of the cost-effectiveness of surgical intervention, and global disparities in surgical care. Nonetheless, there ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0585-2
更新日期：2010-11-01 00:00:00
abstract：:In 1947, a patient with metastatic islet cell tumor was treated for intractable ulcer disease at the University of Chicago Medical Center. Eight years later, in retrospect, it was recognized that he and another patient had the Zollinger-Ellison syndrome (ZE). From 1947 until the present, 30 patients with the ZE syndro...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658530
更新日期：1990-05-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the short- and long-term outcomes of malnourished gastric cancer patients who underwent laparoscopic or open radical gastrectomy. BACKGROUND:Preoperative malnutrition is an independent risk factor for postoperative mortality and morbidity in major gastrointestinal surgery...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4138-9
更新日期：2018-01-01 00:00:00
abstract：:Hepatobiliary (HB) surgery is a challenging surgical subspecialty that requires highly specialized training and an adequate level of experience in order to be performed safely. As a result, minimally invasive HB surgery has been met with slower acceptance as compared to other subspecialties, with many surgeons in the ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-013-2276-2
更新日期：2013-12-01 00:00:00
abstract：:The acid-base balance from the postoperative day (POD) 1 to POD 3 after cirrhotic liver resection was investigated in relation to operative outcome by conducting a retrospective study on the changes in arterial ketone body ratio (AKBR), which reflects the hepatic mitochondrial redox state, and arterial blood gas analy...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01655722
更新日期：1993-01-01 00:00:00
abstract：:Outside Japan portosystemic shunts have been favored as the surgical procedure of choice for the management of portal hypertension of noncirrhotic etiology. Devascularization procedures have resulted in high rebleed rates probably owing to a limited extent of devascularization. We performed this study to assess the ef...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900641
更新日期：1999-11-01 00:00:00
abstract：:Thoracic and thoracoabdominal penetrating wounds are frequently encountered in urban medical centers in the United States. This study was undertaken to determine the clinical characteristics and in hospital outcome of these injuries. This was a longitudinal, nonblinded study using the established standard of care of p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF03215862
更新日期：2001-09-01 00:00:00
abstract：:Childhood papillary thyroid carcinoma is associated with more locally aggressive and more frequent distant disease than its adult counterpart. Recurrence rates tend to be higher in children, but cause-specific mortality remains low. Optimal initial treatment of childhood papillary thyroid carcinoma should include tota...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-004-7605-z
更新日期：2004-12-01 00:00:00
abstract：BACKGROUND:Across Nepal, anesthesia at a district level is provided mostly by non-doctor anesthesia providers (anesthesia assistants-AAs). Nepal's Government recognized the need to sustain competence with continuous professional development and to upgrade 6-month trained working AAs to professional equivalence with the...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4273-3
更新日期：2017-12-01 00:00:00
abstract：:The most appropriate approach to treating hepatocellular carcinoma (HCC) in the caudate lobe has not yet been determined. A series of 197 patients who had undergone curative hepatic resection for HCC were analyzed. Fifteen patients had HCC in the caudate lobe: three in the Spiegel lobe (SP), three in the caudate proce...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7341-4
更新日期：2004-07-01 00:00:00
abstract：:A marked change toward a more conservative approach in the treatment of abdominal trauma has been noted, especially during the last decade. This change in regimen was first seen in the handling of splenic trauma, initiated by pediatric surgeons. Later, the concept of conservative management was also introduced among a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658672
更新日期：1990-07-01 00:00:00
abstract：:Radiologically demonstrable pancreatic endocrine tumors are a frequent requirement for exploration in patients with multiple endocrine neoplasia type I (MEN-I). Such delayed intervention is accompanied by a 30% to 50% incidence of pancreatic endocrine metastases. This study explores biochemical tumor markers and opera...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900451
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:Despite the good results reported after laparoscopic fundoplication, failure is still a major problem. Hiatal disruption is one of the common patterns of anatomical failure. The aim of this study was to compare the results of suture repair of diaphragmatic crura with routine polypropylene mesh reinforcement ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9066-7
更新日期：2007-11-01 00:00:00
