Abstract:
BACKGROUND:In patients with negative sentinel lymph node biopsy (SLNB), axillary dissection (AD) can be avoided to reduce morbidities. However, there is only limited data on the rate of positive non-SLN (NSLN) in those who have micrometastasis and isolated tumor cells (ITC) in the literature. METHODS:We did a retrospective review of all clinically node-negative breast cancer patients with SLNB done at our unit from January 2001 to June 2011. Multivariate analysis was adopted to evaluate the risk factors for NSLN metastasis. Difference in 5-year disease-free survival (DFS) was evaluated with log-rank test. RESULTS:Five-hundred and thirty-seven patients underwent SLNB; 161 (30%) had positive SLN on frozen section (FS), 50 of these patients (31%) had NSLN metastasis, 25 patients had negative SLN on FS but were found to have micrometastasis on histopathology, and only 1 (4%) of them had NSLN metastasis, while 14 patients were found to have ITC in SLN; none of them had NSLN metastasis. Multivariate analysis found that the number of SLN harboring micrometastasis is the only independent risk factor for NSLN metastasis in patients with micrometastasis (p value = 0.008). On the contrary; tumor size, grade, and biology were not associated with NSLN metastasis. 5-year DFS in patients with macrometastasis in SLN was 94.2%, while that in patients with micrometastasis and ITC was 100% (p value <0.001). CONCLUSION:NSLN metastasis in those who only have micrometastasis and ITC is rare, and 5-year DFS is significantly better in this group of patients as well. It is therefore a routine practice in our unit to omit AD in patients with micrometastasis and ITC on SLN.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Co M,Kwong Adoi
10.1007/s00268-015-2984-xsubject
Has Abstractpub_date
2015-06-01 00:00:00pages
1438-42issue
6eissn
0364-2313issn
1432-2323journal_volume
39pub_type
杂志文章abstract:INTRODUCTION:Covid-19 has had a significant impact on all aspects of health care. We aimed to characterise the trends in emergency general surgery at a district general hospital in Scotland. METHODS:A prospective cohort study was performed from 23/03/20 to 07/05/20. All emergency general surgery patients were included...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05760-3
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:The European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire-Cancer (QLQ-C30) and the site-specific module for gastric cancer (QLQ-STO22) have seldom been used to measure the postoperative health-related quality of life (HRQOL) in Japanese gastric cancer patients. The ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0860-2
更新日期:2011-02-01 00:00:00
abstract::Personalized genomic medicine and surgery (PGMS) represents a new approach to health care that customizes patients' medical treatment according to their own genetic information. This new approach is the result of increased knowledge of the human genome and ways this information can be applied by physicians in the medi...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-011-1056-0
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The skin is closed in open appendectomy traditionally with few interrupted nonabsorbable sutures. The use of this old method is based on a suggestion that this technique decreases wound infections. In pediatric surgery, skin closure with running intradermal absorbable sutures has been found to be as safe as ...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-012-1664-3
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:As more patients undergo diagnostic thyroid surgery, the development of posthemithyroidectomy hypothyroidism is becoming a major concern. We hypothesized that the preoperative thyrotropin (thyroid-stimulating hormone, TSH) level and ultrasonographically measured thyroid volume, both commonly available in thy...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9717-3
更新日期:2008-11-01 00:00:00
abstract::During the past four decades, especially in recent years, various active adjuvant therapies combined with surgery have improved the outcome in cases of cancer of the esophagus. However, no optimum adjuvant therapy has been determined. From 1981 to 1992, 341 patients with regional and distant node metastasis who underw...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00316819
更新日期:1994-05-01 00:00:00
abstract:BACKGROUND:In the past decade, Enhanced Recovery after Surgery (ERAS) protocols have been implemented in several fields of surgery. With these protocols, a faster recovery and shorter hospital stay can be accomplished without an increase in morbidity or mortality. The purpose of this study was to review systematically ...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-013-2044-3
更新日期:2013-08-01 00:00:00
abstract::Axillary dissection in patients with breast cancer is associated with significant morbidity. Because 85% of the patients with a cancer < or = 1 cm have negative axillary nodal status, axillary dissection in these patients is only a staging procedure. A study of the sentinel lymph node (SLN) biopsy has been developed t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0272-4
更新日期:2002-05-01 00:00:00
abstract::Left untreated, aneurysmal disease of the abdominal aorta is a highly lethal condition. Standard transabdominal repair of aortic aneurysm, although successful and durable, continues to be plagued by significant morbidity, mortality, and cost. Placement of an endovascular graft through a femoral arteriotomy is a new te...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900101
更新日期:1996-07-01 00:00:00
abstract::Congenital short colon (CSC) is a condition in which the colon is replaced, wholly or partially, by a dilated pouch together with anorectal malformation and a colourinary fistula. Most of the reported series have been from northern India where this malformation is frequent. This paper details the management of 108 pat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900019
更新日期:1996-01-01 00:00:00
abstract::In 141 patients with chronic pancreatitis and an inflammatory enlargement of the head of the pancreas, a duodenum-preserving resection of the head of the pancreas was performed within a 16-year period. The hospital mortality was 0.7%; the late mortality was 5%. Seventy-seven percent of the patients were completely fre...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01670550
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Mechanical bowel obstruction cases constitute an important place in emergency health care services. In this study, bowel obstructions caused by intra-abdominal tumors were compared with those without tumoral causes. PATIENTS AND METHODS:A total of 155 cases of mechanical bowel obstruction diagnosed were r...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0440-z
更新日期:2006-07-01 00:00:00
abstract:BACKGROUND:Burns are a major public health concern, affecting mostly low- and middle-income countries. However, there is a lack of epidemiological studies on burns in these countries, particularly in Latin American countries. Our aim was to analyze nationwide demographic, epidemiological and economic characteristics of...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3988-5
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Significant barriers limit the safe and timely provision of surgical and anaesthetic care in low- and middle-income countries. Nearly one-half of Mongolia's population resides in rural areas where the austere geography makes travel for adequate surgical care very difficult. Our goal was to characterize the a...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0904-7
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The burden of emergency general surgery conditions is high in sub-Saharan Africa, and poor access to surgical care leads to poor patient outcomes. We examined the trends in mortality in patients presenting with an acute abdomen to a referral hospital. METHODS:A retrospective analysis of the prospectively co...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05468-4
更新日期:2020-07-01 00:00:00
abstract::Because of the rarity of adrenocortical carcinoma, survival rates and the prognosis for patients who have undergone operation are not well known. The purpose of the French Association of Endocrine Surgery was to evaluate these factors over an 18-year period. A trend study was associated to assess changes in the clinic...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0047-y
更新日期:2001-07-01 00:00:00
abstract::We sought to determine whether early eschar excision en masse (EEE) at one operation would be effective in the prevention and treatment of postburn organ dysfunction (OD) and multiple organ dysfunction syndrome (MODS). A total of 60 patients, with total body surface burned area over 35% and a third degree burn area ov...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900661
更新日期:1999-12-01 00:00:00
abstract:BACKGROUND:We aimed to describe the pattern of solid organ injuries (SOIs) and analyze the characteristics, management and outcomes based on the multiplicity of SOIs. METHODS:A retrospective study in a Level 1 trauma center was conducted and included patients admitted with blunt abdominal trauma between 2011 and 2014....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4087-3
更新日期:2017-11-01 00:00:00
abstract:BACKGROUND:The appropriate surgical approach for hepatocellular carcinoma (HCC) patients of Child-Pugh class B is unclear. The aim of this study was to clarify the prognostic factors after hepatectomy in Child-Pugh class B patients and to delineate the selection criteria for hepatectomy. METHODS:One hundred fifty pati...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0929-y
更新日期:2011-04-01 00:00:00
abstract::We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7088-3
更新日期:2004-03-01 00:00:00
abstract:BACKGROUND:The goal of the present study was to evaluate the effects of preoperative oral carbohydrate supplementation (OCH) on the postoperative metabolic stress response of patients undergoing elective abdominal surgery. METHODS:The study was designed as a controlled, prospective, cohort study including 38 patients ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1590-4
更新日期:2012-08-01 00:00:00
abstract::Aerodigestive tract injuries in the neck are found in about 7% of penetrating neck injuries and are very rare in blunt trauma. A combination of a good physical examination with endoscopy and esophagography can reliably diagnose all significant injuries. Airway control in laryngotracheal trauma is the most urgent prior...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-001-0057-9
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:We assessed whether the simultaneous sequential strategy could (1) achieve additional sinus restoration for those patients who were not in sinus rhythm while coming off bypass after modified left maze procedure and (2) attain the same long-term success rates as the bi-atrial maze procedure in patients with p...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-006-0382-0
更新日期:2006-10-01 00:00:00
abstract:INTRODUCTION:Percutaneous needle biopsy (PNB) is the standard of care for diagnosis of breast lesions. Rates of excisional biopsy for breast diagnosis in North America have been reported at approximately 35 %, although significant regional variation exists. A target rate of PNB for diagnosis of breast abnormalities is ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3293-0
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The management of positive ductal margins with carcinoma in situ (R1-CIS) after resection is controversial. The aim of this study was to evaluate the impact of R1-CIS on survival in patients who underwent resection for distal cholangiocarcinoma. METHODS:We enrolled 121 consecutive patients with distal chola...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05799-2
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Tumor size has been advocated as possible risk factors for occult central lymph node metastases (CNM) in papillary thyroid carcinoma (PTC) patients. This prospective study evaluated factors that could identify patients at higher risk of occult CNM, especially comparing micro-PTC and macro-PTC. METHODS:One h...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4390-z
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Patients with renal hyperparathyroidism (RHPT) are susceptible to major electrolyte fluctuations following parathyroidectomy, which may predispose them to early readmission. The purpose of this study is to evaluate risk factors for readmission in patients undergoing parathyroidectomy for RHPT. METHODS:Patie...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4823-3
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Construction of a gastric tube that is well perfused with blood during esophagectomy is the most important factor in avoiding anastomotic leakage. We clarified the hemodynamics of the reconstructed gastric tube with indocyanine green (ICG) fluorescence. METHODS:In 20 patients undergoing gastric tube reconst...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2237-9
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:The present study evaluated outcomes of patients undergoing proximal diversion using either a loop ileostomy or loop colostomy following distal colorectal resection for malignant and non-malignant disease. METHODS:A literature search of the Medline, Ovid, Embase and Cochrane databases was performed to ident...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-006-0218-y
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:The Acute Care Surgery (ACS) model was developed as a dedicated service for the provision of 24/7 nontrauma emergency surgical care. This systematic review investigated which components are essential in an ACS model and the state of implementation of ACS models worldwide. METHODS:A literature search was con...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-020-05536-9
更新日期:2020-08-01 00:00:00