Abstract：
BACKGROUND:Tumor size has been advocated as possible risk factors for occult central lymph node metastases (CNM) in papillary thyroid carcinoma (PTC) patients. This prospective study evaluated factors that could identify patients at higher risk of occult CNM, especially comparing micro-PTC and macro-PTC. METHODS:One hundred and eighty-six patients were recruited. All the patients had cN0 clinically unifocal PTC and underwent total thyroidectomy and bilateral prophylactic central neck dissection. Risk factors for occult CNM in micro- and macro-PTC patients were evaluated. RESULTS:Eighty-two patients showed CNM. The rate of CNM did not differ among different sizes cut off (≤20 mm, ≤10 mm, ≤5 mm P = NS). Significantly more pN1a than pN0 patients had pT3 tumors (35/82 vs. 26/104) (P < 0.05), extracapsular invasion (35/82 vs. 22/104) (P < 0.01) and microscopic multifocal disease (50/82 vs. 47/104) (P < 0.05). Independent risk factors for CNM were extracapsular invasion and multifocality at multivariate analysis. Risk factors for CNM in 77 micro-PTC were extracapsular invasion (16/31 pN1 vs. 10/46 pN0, P < 0.05) and multifocality (21/31 pN1 vs. 16/46 pN0, P < 0.01). Among 109 macro-PTC, risk factors for CNM were angioinvasion (15/51 pN1 vs. 7/58 pN0, P < 0.05) and classic PTC at the final histology (PTC vs. tall cell variant vs. follicular variant PTC) (P < 0.05). CONCLUSIONS:Risk factors for CNM can differ between micro- and macro-PTC, but no preoperatively known clinical parameter is predictor of CNM in cN0 clinically unifocal PTC.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Sessa L,Lombardi CP,De Crea C,Tempera SE,Bellantone R,Raffaelli Mdoi
10.1007/s00268-017-4390-zsubject
Has Abstractpub_date
2018-03-01 00:00:00pages
623-629issue
3eissn
0364-2313issn
1432-2323pii
10.1007/s00268-017-4390-zjournal_volume
42pub_type
杂志文章abstract：OBJECTIVE:Mirizzi syndrome (MS) is an uncommon presentation of cholelithiasis. This study aims to find the incidence and analyze the outcome of management of this condition at Riyadh Medical Complex (RMC) with particular reference to diagnostic methods and outcome of surgical treatment. METHODS:Retrospective study on ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0100-3
更新日期：2005-12-01 00:00:00
abstract：:Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6264-1
更新日期：2002-09-01 00:00:00
abstract：BACKGROUND:Scarce data are available on the characteristics of postoperative organ failure (POF) and mortality after gastrectomy. We aimed to describe the causes of organ failure and mortality related to gastrectomy for gastric cancer and to identify patients with POF who are at a risk of failure to rescue (FTR). METH...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05382-9
更新日期：2020-05-01 00:00:00
abstract：:The expression of Fas ligand on tumor cells may counterattack the host's immunity and worsen the prognosis. Knowledge of the prognostic impact of Fas ligand on patients with hepatocellular carcinoma (HCC) after hepatectomy is still limited. Fas ligand expression in HCCs was examined in 59 patients who underwent hepate...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7254-2
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND:Typhoid fever incidence and complications, including intestinal perforation, have declined significantly in high-income countries, with mortality rates <1%. However, an estimated 10.9 million cases still occur annually, most in low- and middle-income countries. With the availability of a new typhoid conjugat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05567-2
更新日期：2020-09-01 00:00:00
abstract：:The effects of pneumoperitoneum on the lower esophageal sphincter (LES) were evaluated during laparoscopic operation for esophageal achalasia. Intraoperative manometry was performed in three patients who underwent laparoscopic cardiomyectomy with Dor's fundoplication and five patients who underwent laparoscopic cholec...
journal_title：World journal of surgery
pub_type： 杂志文章
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更新日期：1996-10-01 00:00:00
abstract：BACKGROUND:Never events (NEs) are serious clinical incidents that cause potentially avoidable harm and impose a significant financial burden on healthcare systems. The purpose of this study was to identify common never events. METHODS:We analysed the NHS England NE data from 2012 to 2020 to identify common never event...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05867-7
更新日期：2021-03-01 00:00:00
abstract：BACKGROUND:Few guidelines exist for the initial management of wounds in disaster settings. As wounds sustained are often contaminated, there is a high risk of further complications from infection, both local and systemic. Healthcare workers with little to no surgical training often provide early wound care, and where r...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-014-2663-3
更新日期：2015-04-01 00:00:00
abstract：:In the Surgical Department of the University of Erlangen, 307 reconstructions in all areas of the arterial tree were performed with PTFE (GORE-TEX) grafts, of which 188 were performed in the femoral-popliteal and femoral-crural areas. Femoral-popliteal bypass grafts above the knee joint remained patent in 93% of the p...
journal_title：World journal of surgery
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
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journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658869
更新日期：1989-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4234-x
更新日期：2018-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00295930
更新日期：1995-09-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0585-2
更新日期：2010-11-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900571
更新日期：1999-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1207-3
更新日期：2011-11-01 00:00:00
abstract：:Pancreatic endocrine tumors (PETs) may be sporadic or inherited in the multiple endocrine neoplasia type 1 (MEN-1) syndrome. The inherited form is caused by mutations of the MEN-1 gene, which functions as a tumor suppressor gene and maps to chromosome 11q13. These tumors tend to have a better prognosis than their spor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-4062-4
更新日期：2002-07-01 00:00:00
abstract：:Most of the work of host defense has been carried out in mixed patient populations. It is now clear that elective preoperative surgical patients have totally different host defense capabilities as compared to posttrauma patients or those suffering from peritonitis. Specific cell-mediated immune studies need to be repe...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01664871
更新日期：1990-03-01 00:00:00
abstract：:Axillary clearance in node-negative breast cancer patients is performed only for staging and prognostic purposes. The sentinel node concept may provide an alternative conservative approach for these patients. This paper reports on the learning experience with lymphatic mapping involving the use of patent blue dye for ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910054
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:In patients with negative sentinel lymph node biopsy (SLNB), axillary dissection (AD) can be avoided to reduce morbidities. However, there is only limited data on the rate of positive non-SLN (NSLN) in those who have micrometastasis and isolated tumor cells (ITC) in the literature. METHODS:We did a retrospe...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2984-x
更新日期：2015-06-01 00:00:00
abstract：BACKGROUND:Surgical care is emerging as a crucial issue in global public health. Methodology is needed to assess the impact of surgical care from a public health perspective. METHODS:A consensus opinion of a group of surgeons, anesthesiologists, and public health experts was established regarding the methodology for e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0261-6
更新日期：2010-03-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7446-9
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:The extent to which obesity and genetics determine postoperative complications is incompletely understood. METHODS:We performed a retrospective study using two population cohorts with electronic health record (EHR) data. The first included 736,726 adults with body mass index (BMI) recorded between 1990 and ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05202-9
更新日期：2020-01-01 00:00:00
abstract：:Although widely practiced, laparoscopic appendectomy (LA) has not met with universal approval. Several controlled trials have been conducted, some in favor, others not. The goal of this review was to ascertain (1) if laparoscopy was capable of improving the diagnostic and therapeutic difficulties encountered during op...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900587
更新日期：1999-08-01 00:00:00
abstract：BACKGROUND:Alternative methods to overcome limitations of electromyogram (EMG) tube applied for intraoperative neuromonitoring (IONM) of recurrent laryngeal nerve (RLN) during thyroidectomy have been introduced. In this study, we evaluated the feasibility of adhesive skin electrodes for IONM of RLN in patients who unde...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05208-3
更新日期：2020-01-01 00:00:00
abstract：:Studies have recorded significant patient discomfort during flexible sigmoidoscopy when it is performed without sedation/analgesia. This study observed whether a single dose of 50 mcg intravenous fentanyl reduces pain, improving compliance, acceptability, and completion rates. In a prospective study, 109 consecutive p...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
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更新日期：2004-09-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to compare the short- and long-term outcomes of malnourished gastric cancer patients who underwent laparoscopic or open radical gastrectomy. BACKGROUND:Preoperative malnutrition is an independent risk factor for postoperative mortality and morbidity in major gastrointestinal surgery...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4138-9
更新日期：2018-01-01 00:00:00
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journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9795-2
更新日期：2009-01-01 00:00:00
abstract：:Experience with the use of nylon fishing line for surgical sutures has been reported from several African countries. A recent publication suggested that fishing line and an injection needle may provide an atraumatic suture that is especially suitable for intracutaneous skin closures. This article provides further empi...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00268-003-7323-y
更新日期：2004-04-01 00:00:00
abstract：OBJECTIVE:The aim of the study was to describe the perioperative and long-term results of carotid endarterectomy (CEA) in patients aged 60 or less and compare them to patients of more advanced age in a retrospective single-centre case-control study. METHODS:From January 1996 to December 2014, 5893 consecutive CEAs wer...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4133-1
更新日期：2018-01-01 00:00:00
