Abstract：
:Studies have recorded significant patient discomfort during flexible sigmoidoscopy when it is performed without sedation/analgesia. This study observed whether a single dose of 50 mcg intravenous fentanyl reduces pain, improving compliance, acceptability, and completion rates. In a prospective study, 109 consecutive patients were offered the option of 50 mcg intravenous fentanyl or no analgesia. Patient's pre-procedure expectations, objective pain scores, and willingness to undergo a subsequent procedure using the same technique were recorded. Endoscopist recorded the success, complications, and objective pain scores for each patient. Of the 46 patients (42%) choosing fentanyl, 9 (20%) experienced moderate/severe pain as against 26 (41%) of the 63 patients (58%) opting for no analgesia (p < 0.05). Further, 52% receiving fentanyl had a significantly better experience compared to their pre-procedure expectations as against 33% who received no analgesia (p < 0.05). No patient receiving fentanyl expressed unwillingness to undergo the procedure again using the same technique, whereas 16 (25%) of those receiving no analgesia indicated they would not (p < 0.01). Endoscopists recorded moderate/severe pain in 13 patients (12%), whereas 35 patients (32%) recorded moderate/severe pain (p < 0.001). Analgesia for endoscopy should involve patient choice. However, a single dose of 50 mcg fentanyl reduced patient discomfort and improved satisfaction. It appeared safe and likely to improve patient compliance and acceptability for flexible sigmoidoscopy.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Basu S,Krishnamurthy B,Walsh THdoi
10.1007/s00268-004-7374-8keywords:
subject
Has Abstractpub_date
2004-09-01 00:00:00pages
930-4issue
9eissn
0364-2313issn
1432-2323journal_volume
28pub_type
临床试验,杂志文章abstract：:Papillary thyroid carcinoma is a frequent thyroid cancer. Many factors have been reported to be of prognostic importance, but the significance of biologic factors suggesting aggressiveness and proliferating activity has not been sufficiently documented. Conventional prognostic factors such as age, extrathyroidal invas...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900551
更新日期：1998-12-01 00:00:00
abstract：BACKGROUND:Pancreatic cancer has higher concentrations of angiotensin II compared with other cancers. This study sought to assess the effect of angiotensin II receptor blockers (ARBs) on survival of patients undergoing resection using a large, nationally representative dataset. METHODS:Patients undergoing pancreatic c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4021-8
更新日期：2017-09-01 00:00:00
abstract：:Although emergency department thoracotomy (EDT) is often considered a controversial "last chance" method of resuscitation, we hypothesized that EDT performed in a busy urban Level I trauma center has significant salvage rates despite the absence of traditional survival predictors. A retrospective review revealed that ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9392-9
更新日期：2008-04-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux disease is common in Western societies, although the prevalence of reflux symptoms in the community is not well described. In this study we determined the prevalence of symptoms of gastroesophageal reflux and other "esophageal" symptoms, and the consumption of medication for reflux ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9780-9
更新日期：2009-01-01 00:00:00
abstract：:The effects of splenectomy in 41 patients managed from 1982 to 1995 at Sher-i-Kashmir Institute of Medical Sciences, Srinagar (Jammu and Kashmir), India, were studied. Immune thrombocytopenic purpura (ITP) was the main indication for therapeutic splenectomy among all the hematologic disorders. The mean age was 30 year...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910017
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Postoperative ileus is a common problem with significant clinical and economic consequences. We hypothesized that Gastrografin may have therapeutic utility by accelerating the recovery of postoperative ileus after colorectal surgery. The aim of this trial was to study the impact of oral Gastrografin administ...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-015-3260-9
更新日期：2016-01-01 00:00:00
abstract：:Cancers of the distal rectum (less than 7.5 cm from the anal verge) that are freely mobile, moderately well or well differentiated, less than 4 cm in size, limited to the bowel wall, and without evidence of metastasis should be considered candidates for treatment with electrocoagulation for cure. Tumor cell ploidy and...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02104447
更新日期：1992-05-01 00:00:00
abstract：:Video-assisted thyroidectomy, although an increasingly used method to treat benign thyroid nodules, is rarely used to treat thyroid cancer. We performed gasless video-assisted total thyroidectomy for the treatment of papillary carcinoma of the thyroid. The patients were two men and five women with ages ranging from 29...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7446-9
更新日期：2004-09-01 00:00:00
abstract：BACKGROUND:Schistosomiasis is a waterborne trematode with numerous subtypes affecting different areas of the body. Rob Ferreira Hospital is located in an endemic area for schistosomiasis in the Lowveld region of South Africa. We set out to determine the prevalence of Sch istosoma in appendicitis. METHODS:From 2009 to ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2954-3
更新日期：2015-05-01 00:00:00
abstract：:In the original article there is an error in Fig. 2. Following is the corrected figure. ...
journal_title：World journal of surgery
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00268-018-04886-9
更新日期：2019-03-01 00:00:00
abstract：BACKGROUND:The management of positive ductal margins with carcinoma in situ (R1-CIS) after resection is controversial. The aim of this study was to evaluate the impact of R1-CIS on survival in patients who underwent resection for distal cholangiocarcinoma. METHODS:We enrolled 121 consecutive patients with distal chola...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05799-2
更新日期：2021-01-01 00:00:00
abstract：:The imaging characteristics of diagnostic ultrasound (US) are determined by the ultrasonic properties of tissue. The velocity of propagation of US and the attenuation are the 2 most important parameters. These determine the frequency with which the tissues may be imaged, which in turn sets a fundamental limit on the a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910026
更新日期：2000-02-01 00:00:00
abstract：BACKGROUND:Parathyroid cancer is rare. Differentiating parathyroid carcinoma from degenerative changes at histopathology can be difficult and studies investigating the value of single immunohistochemical markers have had variable results. In this study we aimed to investigate whether a panel of immunohistochemistry mar...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2700-2
更新日期：2014-11-01 00:00:00
abstract：:Incisional hernia is a serious postoperative complication of laparotomy. Selecting an appropriate suture material may lessen such morbidity. This study undertook a prospective, randomized comparison of early-absorbable polyglactin 910 suture versus late-absorbable polydioxanone loop suture for fascial closure after ab...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002689910120
更新日期：2000-06-01 00:00:00
abstract：:The aim of this study was to investigate the epidemiologic characteristics and changing patterns of gallstone disease in Korea over a recent 20-year period. A total of 4020 gallstone patients who had undergone surgery at Seoul National University Hospital during 1981-2000 were analyzed according to periods: period I (...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6879-x
更新日期：2004-02-01 00:00:00
abstract：BACKGROUND:Despite wide acknowledgement of the importance of sarcopenia and prognostic markers such as the neutrophil-to-lymphocyte ratio, the impact on cancer patient survival of the timing of sarcopenia's emergence and its severity is not well understood, nor is the association between sarcopenia and prognostic marke...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05344-w
更新日期：2020-05-01 00:00:00
abstract：:Extracorporeal life support has evolved considerably over the past two decades. Once considered as salvage or experimental therapy in adults, extracorporeal membrane oxygenation (ECMO) is evolving into a mainstream treatment for adult critical care. This is especially true in trauma and high-risk surgical patients, wh...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-016-3586-y
更新日期：2017-05-01 00:00:00
abstract：BACKGROUND:Laparoscopic reoperative anti-reflux surgery (ARS) has a significantly higher morbidity than laparoscopic primary ARS; however, it is not known whether the same pattern exists within the robotic approach. We aimed to evaluate the safety and efficacy of robotic reoperative ARS in comparison with primary robot...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4708-5
更新日期：2018-12-01 00:00:00
abstract：:Worldwide, traffic deaths are 500,000 per year and growing. Four nations, China, India, Russia, and the United States of America, have reached levels of 45,000-50,000 traffic deaths per year, although the nature of the problem is quite different in fully motorized countries from what it is in motorizing countries. In ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF02104436
更新日期：1992-05-01 00:00:00
abstract：OBJECTIVE:Gastroesophageal reflux disease (GERD) symptoms are commonly reported in primary hyperparathyroidism (pHPT). Although a calcium-mediated cause-and-effect relationship has been suggested, it remains unknown if parathyroidectomy improves GERD symptoms. METHODS:Over a 22-month period, 1,175 (39%) of 3,000 conse...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2876-5
更新日期：2015-03-01 00:00:00
abstract：BACKGROUND:Geriatric collaborative care models improve postoperative outcomes for older adults. However, there are limited data exploring how preoperative geriatric assessment may affect surgical cancellations. METHODS:This is a single-center retrospective cohort analysis. Patients enrolled in the Perioperative Optimi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05772-z
更新日期：2021-01-01 00:00:00
abstract：BACKGROUND:Because the feasibility and safety of laparoscopic approaches for the treatment of perforated peptic ulcer (PPU) have been fully recognized, laparoscopic repair of PPU (LPPU) has become a widely accepted procedure. Following closure of a PPU, the rationale to add an omental patch is based on the assumptions ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2503-5
更新日期：2014-08-01 00:00:00
abstract：:Carnitine, an important carrier of free fatty acid that is transported into mitochondria for beta-oxidation, was thought to be one of the key factors in the regulation of liver regeneration. If the carnitine content is insufficient in the hepatocyte, it might impair the energy substrate's transport and the energy char...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900347
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:It is generally believed that the accompanying conditions in patients with inflammatory bowel disease (IBD) are associated with a high incidence of surgical site infection (SSI), and sometimes these patients are classified as compromised hosts without definitive clinical evidence. The aim of this study was t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-9934-4
更新日期：2009-05-01 00:00:00
abstract：:Portal azygos disconnection, using vein ligatures and a circumferential hemostatic suture of the gastric wall at the level of the upper pole, is a simple and a rapid technique that effectively controls bleeding from esophagogastric varices. Its low mortality rate in emergency cases or poor-risk patients can be of grea...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01659042
更新日期：1989-05-01 00:00:00
abstract：BACKGROUND:Total thyroidectomy is a well-established surgical approach for the management of papillary thyroid cancer (PTC). However, the best surgical approach for papillary microcarcinoma is nowadays still debated. Both total thyroidectomy and simple lobectomy are used. We report the experience of a single University...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3327-7
更新日期：2016-03-01 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis, as a majority of patients present with advanced disease. Current adjuvant strategies for metastatic patients include mitotane or other cytotoxic agents and carry a significant morbidity as well as a low (<10 %) 5-year sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2532-0
更新日期：2014-06-01 00:00:00
abstract：:We analyzed clinical features and genetic alterations in the noncancerous and cancerous biliary lesions obtained from pancreaticobiliary maljunction (PBM) patients. Gallbladder (GB) and bile duct (BD) lesions were obtained surgically from 36 patients with PBM, and polymerase chain reaction (PCR) methods were used to e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0187-0
更新日期：2002-01-01 00:00:00
abstract：:The major goal of wound healing biology is to determine how a wound can be induced to repair damaged tissue faster and more efficiently. Enhancement of dermal and epidermal regeneration is an extremely important goal for the treatment of many different types of wounds. Exogenous application of growth factors to the wo...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-004-2062-2
更新日期：2005-01-01 00:00:00
abstract：AIM:To investigate the learning curve and perioperative outcomes of single-site robotic cholecystectomy during the first 102 cases by a single surgeon. MATERIALS AND METHODS:A retrospective review of a prospectively maintained database was performed on the first 102 cases of single-site robotic cholecystectomy. Patien...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3135-0
更新日期：2015-10-01 00:00:00
