Systemic and peritoneal host defense in peritonitis.

Abstract:

:Most of the work of host defense has been carried out in mixed patient populations. It is now clear that elective preoperative surgical patients have totally different host defense capabilities as compared to posttrauma patients or those suffering from peritonitis. Specific cell-mediated immune studies need to be repeated in these 2 patient groups as well. What will contribute clinical relevance to these studies will be the means to correct the defects. If these defects or--more correctly termed--abnormalities of host defense are, indeed, important and contribute to an increased sepsis rate and mortality from sepsis in affected patients, then correcting them should reduce these complications. This hypothesis can only be tested when such means become available. The issues of most interest in the next few years will be the significance of serum albumin in host outcome, the role of immunomodulators, the involvement of cytokines in the overall process of host defense, and the use of specific nutritional support regimens targeted to the immune system.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Christou NV

doi

10.1007/BF01664871

subject

Has Abstract

pub_date

1990-03-01 00:00:00

pages

184-90

issue

2

eissn

0364-2313

issn

1432-2323

journal_volume

14

pub_type

杂志文章,评审
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    doi:10.1007/BF02393582

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    doi:10.1007/s00268-018-4742-3

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  • Fishing line suture: cost-saving alternative for atraumatic intracutaneous skin closure--randomized clinical trial in Rwanda.

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    journal_title:World journal of surgery

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    journal_title:World journal of surgery

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    doi:10.1007/s00268-005-7728-x

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    authors: Kurmann A,Keller S,Tschan-Semmer F,Seelandt J,Semmer NK,Candinas D,Beldi G

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    pub_type: 杂志文章,meta分析,评审

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    pub_type: 杂志文章

    doi:10.1007/s00268-012-1548-6

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    journal_title:World journal of surgery

    pub_type: 杂志文章

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    更新日期:2017-05-01 00:00:00

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  • Distal Enteral Feeding Helps Blood Sugar Control in Pancreatectomized Patients.

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    authors: Furihata M,Sawada T,Okada T,Ishizuka M,Horie T,Takagi K,Nagata H,Kubota K

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