Abstract：
BACKGROUND:The appropriate surgical approach for hepatocellular carcinoma (HCC) patients of Child-Pugh class B is unclear. The aim of this study was to clarify the prognostic factors after hepatectomy in Child-Pugh class B patients and to delineate the selection criteria for hepatectomy. METHODS:One hundred fifty patients of Child-Pugh class B who underwent hepatectomy were enrolled in this retrospective study (Hx group). Univariate and multivariate analyses were performed to identify prognostic factors. The prognosis was compared with that of 23 patients of Child-Pugh class B who underwent liver transplantation (LT group). RESULTS:The overall survival rate of the Hx group was significantly worse than that of the LT group (5-year survival: 36.0 vs. 78.3%, p = 0.001). In multivariate analyses, diabetes mellitus (p = 0.011), preoperative total bilirubin level ≥ 1.5 mg/dl (p = 0.038), and Child-Pugh score of 8 or 9 (p = 0.038) were independent prognostic factors. Although the overall 5-year survival rate of patients with none of the three adverse prognostic factors was only 50.3%, that of patients with one or more adverse prognostic factors was only 27.2% (p = 0.001). CONCLUSIONS:Hepatectomy may be the optimal initial treatment for HCC patients classified as Child-Pugh class B and without any adverse prognostic factors.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Kuroda S,Tashiro H,Kobayashi T,Oshita A,Amano H,Ohdan Hdoi
10.1007/s00268-010-0929-ysubject
Has Abstractpub_date
2011-04-01 00:00:00pages
834-41issue
4eissn
0364-2313issn
1432-2323journal_volume
35pub_type
杂志文章abstract：:The role of liver transplantation in malignancy has been discussed, but controversially, over the past two decades. This is particularly true for hepatic metastases from neuroendocrine tumors, which have a wide variety of primary tumor localizations, morphologic types, functional activities, and clinical presentations...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0016-5
更新日期：2001-06-01 00:00:00
abstract：BACKGROUND:Insertion of a nasogastric tube (NGT) in an anesthetized, paralyzed, and intubated patient is difficult, and many methods have been proposed to aid in the procedure. We present a simple insertion technique. METHODS:A silicone NGT was made rigid by filling it with distilled water and freezing it. Patients we...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-009-0144-x
更新日期：2009-09-01 00:00:00
abstract：BACKGROUND:We hypothesized that a dedicated collaborative transdisciplinary Geriatric Surgery Service (GSS) will improve care for elderly colorectal surgery patients. METHODS:Patients older than 75 years of age who underwent major colorectal surgery were included in this study. The Geriatric Surgery Service employed a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1112-9
更新日期：2011-07-01 00:00:00
abstract：:Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6541-z
更新日期：2003-02-01 00:00:00
abstract：:This paper investigates methodological limitations of the volume-outcome relationship. A brief overview of quality measurement is followed by a discussion of two important aspects of the relationship. ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7993-8
更新日期：2005-10-01 00:00:00
abstract：BACKGROUND:The selection of the type of fundoplication or the necessity for an added fundoplication after esophagomyotomy (Heller's operation) for the treatment of achalasia remains controversial. The present retrospective study was designed to compare the long-term results of total and partial fundoplication on the my...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9385-8
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis, as a majority of patients present with advanced disease. Current adjuvant strategies for metastatic patients include mitotane or other cytotoxic agents and carry a significant morbidity as well as a low (<10 %) 5-year sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2532-0
更新日期：2014-06-01 00:00:00
abstract：:Over the past three decades Canada has developed an exemplary system of universal health care. However, current financial constraints threaten to undermine the very foundation of the system that represents Canada's respect for social justice. The first of these two articles (Part 1) discusses the unique characteristic...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00298897
更新日期：1994-09-01 00:00:00
abstract：BACKGROUND:The estimation of physiologic ability and surgical stress (E-PASS) has been used to produce a numerical estimate of expected mortality and morbidity after elective gastrointestinal surgery. The aim of this study was to validate E-PASS in a selected cohort of patients requiring liver resections (LR). METHODS...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-9989-2
更新日期：2009-06-01 00:00:00
abstract：BACKGROUND:Neoadjuvant chemotherapy (NC) is standard therapy for patients with locally advanced breast cancer and is increasingly used for early-stage operable disease. Clinical and pathological responses are important prognostic parameters for NC, which aims to achieve a pathological complete response or tumor reducti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9800-9
更新日期：2009-01-01 00:00:00
abstract：:Recent collective reviews have outlined when and how surgeons should treat patients with bile duct injuries after laparoscopic cholecystectomy (LC). However, little is described about other injuries combined with bile duct injuries, for example, hepatic arterial injury and secondary biliary cirrhosis. Fifteen patients...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0120-6
更新日期：2001-10-01 00:00:00
abstract：:The expression CA195 in serum, defined by monoclonal antibody CC3C195 (IgM), was studied in 67 patients with pancreatic cancer and in 138 patients with biliary or pancreatic benign disease. The results were compared with carcinoembryonic antigen (CEA) expression. The overall sensitivity of the CA195 assay (> 12 U/ml) ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00013182
更新日期：1999-03-01 00:00:00
abstract：BACKGROUND:The retained knife blade is an unusual and spectacular injury. The aim of this study was to review our experience with the management of such injuries. METHODS:A retrospective chart review of patients with retained knife blades treated at Groote Schuur Hospital Trauma Centre from January 1996 to December 20...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0514-4
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) plays an essential role in the evaluation of lymph node (LN) metastasis status and the extent of LN dissection in gastric cancer. The aim of our study was to perform a systematic review and meta-analysis for corresponding identification rate and sensitivity of different SLNB...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-020-05900-9
更新日期：2021-01-03 00:00:00
abstract：BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed recently. Although it seems plausible that SILC will be associated with less pain compared to standard 4-port laparoscopic cholecystectomy (LC), there is currently no conclusive comparative study on the postoperative pain iss...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0842-4
更新日期：2011-02-01 00:00:00
abstract：BACKGROUND:The open surgical wound is exposed to cold dry ambient air, resulting in substantial heat loss through radiation, evaporation, and convection. At the same time, anesthesia decreases the patient's core temperature. Despite preventive measures, mild intraoperative hypothermia has been associated with postopera...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-012-1735-5
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:In the past decade, Enhanced Recovery after Surgery (ERAS) protocols have been implemented in several fields of surgery. With these protocols, a faster recovery and shorter hospital stay can be accomplished without an increase in morbidity or mortality. The purpose of this study was to review systematically ...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-013-2044-3
更新日期：2013-08-01 00:00:00
abstract：BACKGROUND:Laparoscopic cholecystectomy (LC) with common bile duct exploration (LCBDE) is nowadays a preferred one-stage treatment. However, the influence of complicated cholecystitis (CC) on LCBDE has rarely been addressed. In the present study we aimed to verify whether severe gallbladder inflammation would adversely...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1696-8
更新日期：2012-10-01 00:00:00
abstract：BACKGROUND:Esophagectomy remains the standard treatment for resectable esophageal cancer, but the cure rate is low. Neoadjuvant therapy has been tried in attempts to prolong survival and reduce tumor recurrence. The aim of this study was to assess the surgical outcomes with and without neoadjuvant treatment for resecta...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0016-6
更新日期：2006-12-01 00:00:00
abstract：:The radiological features of common benign conditions of the breast and the radiological procedures used in the investigation of benign breast disorders are presented. ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658415
更新日期：1989-11-01 00:00:00
abstract：BACKGROUND:The implementation of programs to improve patient safety remains challenging in low- and middle-income countries. The goal of our study was to define the barriers and facilitators to implementation of a perioperative patient safety program in Guatemala. MATERIAL AND METHODS:We conducted semi-structured inte...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05495-1
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:The objectives of this study were to report the clinical and radiological characteristics and outcomes of a series of acute traumatic aortic injuries (ATAIs) with associated injury to major aortic abdominal visceral branches (MAAVBs). METHODS:From January 2000 to August 2011, 10 consecutive major blunt trau...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1536-x
更新日期：2012-07-01 00:00:00
abstract：:The prognosis of patients who undergo resection for pancreatic ductal adenocarcinoma with curative intention is generally poor unless they have early-stage disease. Based on our 25-year experience, the results of 194 patients after a standardized Kausch-Whipple resection for adenocarcinoma of the pancreatic head were ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6659-z
更新日期：2003-03-01 00:00:00
abstract：OBJECTIVE:Radical lymph node dissection (LND) along the bilateral recurrent laryngeal nerve (RLN) is a surgically challenging procedure with a high rate of morbidity. Here, we assessed in a retrospective manner the adequacy of LND along the RLN performed with robot-assisted thoracoscopic esophagectomy (RATE) versus vid...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4179-0
更新日期：2018-02-01 00:00:00
abstract：:It has been widely acknowledged that exomphalos and gastroschisis are two different clinical entities. Their etiology and pathogenesis, however, remain controversial. Several techniques are available for making a prenatal diagnosis of these as well as many other malformations. Some prenatal treatment is possible, but ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658701
更新日期：1993-05-01 00:00:00
abstract：:The most appropriate approach to treating hepatocellular carcinoma (HCC) in the caudate lobe has not yet been determined. A series of 197 patients who had undergone curative hepatic resection for HCC were analyzed. Fifteen patients had HCC in the caudate lobe: three in the Spiegel lobe (SP), three in the caudate proce...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7341-4
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:Total thyroidectomy is now accepted worldwide as the standard surgical procedure for the management of benign bilateral nodular thyroid disease. Hypocalcemia is the most common complication of that procedure and a variety of strategies for diagnosing and managing post-thyroidectomy hypocalcemia have been adv...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-008-9545-5
更新日期：2008-07-01 00:00:00
abstract：:Gastric emptying times and symptoms were recorded in 18 patients after total gastrectomy and either a 15-cm J-pouch (n = 10) or a standard esophagojejunal anastomosis (n = 8). A solid test meal labeled with 99mTc was used to compare the emptying times. The postoperative symptoms and nutritional status were also assess...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01659117
更新日期：1993-09-01 00:00:00
abstract：:Squamous cell carcinoma of the anus (SCCA) is a rare disease in the average population but is an increasing concern among immunocompromised individuals, such as the HIV-seropositive. Coinfection with human papillomavirus (HPV) in this population is common. HPV infection is difficult to clear with a compromised immune ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-008-9835-y
更新日期：2009-04-01 00:00:00
abstract：BACKGROUND:Pain syndromes of somatic and neuropathic origin are considered to be the main causes of chronic pain after open inguinal hernia repair. Nerve-identification during open hernia repair is suggested to be associated with less postoperative chronic pain. The aim of this study was to define clinically relevant s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0376-y
更新日期：2007-02-01 00:00:00
