Abstract:
:Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 patients who underwent surgery at three Danish centers between January 1, 1979 and December 31, 1997 were compared with 2021 age- and gender-matched controls. There was an increased incidence of acute MI up to 10 years prior to surgery [relative risk (RR) 2.5, 95% confidence interval (95% CI) 1.5-4.2] and within the first year following surgery (RR 3.6, 95% CI 1.7-7.6). The risk of MI subsequently declined to a normal level more than 1 year after surgery. Patients with MI prior to diagnosis also had a higher postoperative risk of new infarction than did patients without [odds ratio (OR) 6.0, 95% CI 1.2-30.0]. The risk of hypertension, stroke, congestive heart failure, and diabetes was increased before surgery. More than 1 year after surgery only hypertension and congestive heart failure were more frequent in patients than controls. Preoperative cardiovascular disease was associated with an increased risk of death (RR 1.8, 95% CI 1.1-2.8). Mortality following surgery was higher than in the general population between 1979 and 1990 but not between 1991 and 1997. We concluded that there was an increase in acute MI up to 10 years prior to surgery. The risk of MI decreased to a normal level after surgery, which may be important for preventing cardiovascular disease in patients with primary hyperparathyroidism.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Vestergaard P,Mollerup CL,Frøkjaer VG,Christiansen P,Blichert-Toft M,Mosekilde Ldoi
10.1007/s00268-002-6541-zkeywords:
subject
Has Abstractpub_date
2003-02-01 00:00:00pages
216-22issue
2eissn
0364-2313issn
1432-2323journal_volume
27pub_type
杂志文章abstract::We have previously demonstrated that in 95.6% of malignant thyroid tumors the enzyme thyroid peroxidase (TPO) presents antigenic changes detectable by a monoclonal antibody termed MoAb47. The aim of this study was to investigate the interest of TPO immunodetection for the diagnosis of malignancy on fine-needle aspirat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/BF00353756
更新日期:1994-07-01 00:00:00
abstract:BACKGROUND:Laparoscopic proximal gastrectomy (LPG) is performed as a function-preserving surgery for patients with early proximal gastric malignant tumors; however, whether LPG has advantages postoperatively compared with laparoscopic total gastrectomy (LTG) is debatable, especially with regard to nutritional outcomes....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4625-7
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Since the human genome has been sequenced many mysteries of cell biology have been unravelled, thereby clarifying the pathogenesis of several diseases, particularly cancer. In members of kindreds with certain hereditary diseases, it is now possible early in life to predict with great certainty whether or not...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-006-0616-1
更新日期:2007-03-01 00:00:00
abstract:BACKGROUND:Screening of multiple endocrine neoplasia type 1 (MEN-1) patients is widely recommended because one-fifth succumb to malignant neoplasms. However, recommendations for screening modalities and intervals are based mostly on nonprospective data. METHODS:Thirty-five of 48 MEN-1 patients were evaluated at least ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9983-8
更新日期:2009-06-01 00:00:00
abstract:INTRODUCTION:Hypocalcemia is a well-known complication after total thyroidectomy. Studies have indicated that the presence of low postoperative parathyroid hormone (PTH) levels can predict hypocalcemia. However, definitive study designs are lacking. The aim of this study was to determine whether postoperative PTH alone...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4444-2
更新日期:2018-07-01 00:00:00
abstract:BACKGROUND:Burns are a major public health concern, affecting mostly low- and middle-income countries. However, there is a lack of epidemiological studies on burns in these countries, particularly in Latin American countries. Our aim was to analyze nationwide demographic, epidemiological and economic characteristics of...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3988-5
更新日期:2017-08-01 00:00:00
abstract::Nineteen consecutive patients receiving renal transplants underwent prospective evaluation of their calcium homeostasis for 1 year after transplantation to characterize indices of hyperparathyroidism (HPT) amelioration. All but one underwent dialysis, and six had vitamin D supplementation before grafting. The rapid fa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900446
更新日期:1998-06-01 00:00:00
abstract:INTRODUCTION:Rectus sheath hematoma is rare. It can present to physicians in many specialties, but invariably the surgeon is contacted regarding management. It is frequently difficult to diagnose, which can result in delay of treatment or unnecessary surgery. Its incidence is on the rise. METHODS:We present a series o...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-0702-9
更新日期:2006-11-01 00:00:00
abstract::Patients with obstructive jaundice (OJ) that requires surgery often have malnutrition associated with increased perioperative morbidity. This study investigated the factors influencing nutritional derangements in these patients. A series of 46 OJ patients were investigated prospectively (28 malignant tumors, 18 benign...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680020043
更新日期:2001-04-01 00:00:00
abstract:BACKGROUND:The appropriate surgical approach for hepatocellular carcinoma (HCC) patients of Child-Pugh class B is unclear. The aim of this study was to clarify the prognostic factors after hepatectomy in Child-Pugh class B patients and to delineate the selection criteria for hepatectomy. METHODS:One hundred fifty pati...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0929-y
更新日期:2011-04-01 00:00:00
abstract::This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' di...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067345
更新日期:1992-07-01 00:00:00
abstract::Multiple organ failure (MOF) is considered to be the leading cause of death after severe trauma. Although there is extensive literature on MOF, little is known about the pattern, sequence, and onset of this clinical syndrome. The first goal of this clinical study was to define MOF; the second was to assess the typical...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900067
更新日期:1996-05-01 00:00:00
abstract:BACKGROUND:Hepatocellular carcinoma (HCC) typically recurs following primary treatment. The primary objective of this systematic review was to evaluate the safety and efficacy of ablative therapies for recurrent HCC. The secondary objective was to identify any factors associated with prognosis following ablation for re...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-015-2956-1
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:There is a paucity of data on the presentation and surgical management of pheochromocytoma in developing nations, particularly in Africa. METHODS:This study was a retrospective review, which included all patients managed by the Groote Schuur Hospital/University of Cape Town Endocrine Surgery unit for pheoch...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05420-6
更新日期:2020-06-01 00:00:00
abstract::Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680010228
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Nodal involvement of papillary thyroid carcinoma (PTC) commonly occurs in the paratracheal region and the internal jugular chain. Lymph node metastasis in the parapharyngeal space (PPS) is rare. In this report, we describe our experience and surgical outcomes of patients with PPS metastasis of PTC. METHODS:...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3321-0
更新日期:2016-02-01 00:00:00
abstract::Met protein is a tyrosine kinase receptor for hepatocyte growth factor (HGF). c-Met has morphogenic, mitogenic, and motogenic properties and is overexpressed in many solid tumors. We studied c-met mRNA and protein expression in papillary thyroid carcinomas and nonneoplastic thyroid tissue. The c-met mRNA was detected ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680020167
更新日期:2001-05-01 00:00:00
abstract::Upper dorsal sympathectomy is the only successful therapeutic method for idiopathic palmar hyperhidrosis (IPHH). However, the techniques for sympathetic ablation are still debated. The aim of this study was to compare prospectively two accepted methods for endoscopic sympathetic ablation: resection of T2-T3 ganglia ve...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9160-x
更新日期:2007-10-01 00:00:00
abstract::Large ventral hernias are a significant surgical challenge. "Loss of domain" (LOD) expresses the relationship between hernia and abdominal volume, and is used to predict operative difficulty and success. This systematic review assessed whether different definitions of LOD are used in the literature. The PubMed databas...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4783-7
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Laparoscopic cholecystectomy is first-line treatment for uncomplicated gallstone disease in high-income countries due to benefits such as shorter hospital stays, reduced morbidity, more rapid return to work, and lower mortality as well-being considered cost-effective. However, there persists a lack of uptake...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3851-0
更新日期:2017-05-01 00:00:00
abstract:BACKGROUND:Minimally invasive radio-guided parathyroidectomy (MIRP) has been embraced as an acceptable therapeutic approach to primary hyperparathyroidism. Preoperative sestamibi scanning has facilitated this technique. Here we evaluate the addition of a rapid intraoperative parathyroid hormone (iPTH) assay for patient...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0293-5
更新日期:2006-02-01 00:00:00
abstract::Expression of sialyl-Lewisx (sLex) antigen was studied immunohistochemically in 110 resected human gastric carcinomas using an anti-sLex monoclonal antibody. Lymph node, liver, and peritoneal metastases were clearly more prevalent in tumors expressing high levels of sLex than in those with no or low-level sLex express...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900304
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Barriers to female surgeons entering the field are well documented in Australia, the USA and the UK, but how generalizable these problems are to other regions remains unknown. METHODS:A cross-sectional survey was developed by the International Federation of Medical Students' Associations (IFMSA)'s Global Su...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05199-1
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Recurrent renal hyperparathyroidism (HPT) is a serious problem after parathyroidectomy (PTx). We evaluated the frequency of graft-dependent recurrent HPT and the clinical outcomes after removal of the autograft. METHODS:Between March 1980 and January 2009, 2660 patients underwent total PTx with forearm auto...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0412-9
更新日期:2010-06-01 00:00:00
abstract:BACKGROUND:Geriatric collaborative care models improve postoperative outcomes for older adults. However, there are limited data exploring how preoperative geriatric assessment may affect surgical cancellations. METHODS:This is a single-center retrospective cohort analysis. Patients enrolled in the Perioperative Optimi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05772-z
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Assessment of preoperative physiological status is crucial for optimizing clinical outcomes in patients undergoing surgery for esophageal carcinoma (EC). We aimed to evaluate the prognostic impact of pulmonary dysfunctions and their relationships with other physiological factors, especially sarcopenia, in EC...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05450-0
更新日期:2020-07-01 00:00:00
abstract:BACKGROUND:Only few studies have compared laparoscopic total mesorectal excision (LTME) and open total mesorectal excision (OTME) for rectal cancer with follow-up longer than 5 years. The aim of this study was to compare 10-year oncologic outcomes after LTME and OTME for nonmetastatic rectal cancer. METHODS:We conduct...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3631-x
更新日期:2016-12-01 00:00:00
abstract:BACKGROUND:Acute colonic diverticulitis is a common clinical condition. Severity of the disease is based on clinical, laboratory, and radiological investigations and dictates the need for medical or surgical intervention. Recent clinical trials have improved the understanding of the natural history of the disease resul...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-016-3560-8
更新日期:2016-10-01 00:00:00
abstract::The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01654731
更新日期:1977-01-01 00:00:00
abstract::Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6264-1
更新日期:2002-09-01 00:00:00