Abstract：
BACKGROUND:Hepatocellular carcinoma (HCC) typically recurs following primary treatment. The primary objective of this systematic review was to evaluate the safety and efficacy of ablative therapies for recurrent HCC. The secondary objective was to identify any factors associated with prognosis following ablation for recurrent disease. METHODS:A systematic search of the literature published between January 2000 and December 2013 was undertaken using the PubMed, Medline and Scopus databases. Reference lists from selected studies were manually searched to ensure complete capture of any relevant data. RESULTS:A total of 19 studies were included in the review. The median age of patients undergoing ablation for recurrent HCC was 58 years (range 52-69 years) and 85 % of patients had cirrhosis (range 56-100 %). HCC recurred as a single nodule in 79 % of those treated with ablation (range 46-100 %). There were few significant complications associated with any form of ablation. Sufficient data were only available to allow analysis of survival outcomes following radiofrequency ablation (RFA). After RFA the median, 1, 3 and 5-year survivals were 84 % (73-99 %), 51 % (42-84 %) and 40 % (28-83 %), respectively. The only factor consistently associated with overall survival following ablation for recurrence was the alpha-fetoprotein (AFP) level. CONCLUSION:Comparable survival figures from previously published systematic reviews suggest that hepatic resection is the most effective treatment for recurrent HCC. However, ablation can be a safe and effective option for the majority of patients with recurrent disease who are unsuitable for surgery. Elevated levels of AFP suggest a poorer prognosis following ablation.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Thomasset SC,Dennison AR,Garcea Gdoi
10.1007/s00268-015-2956-1subject
Has Abstractpub_date
2015-05-01 00:00:00pages
1150-60issue
5eissn
0364-2313issn
1432-2323journal_volume
39pub_type
杂志文章,评审abstract：:Hepatobiliary (HB) surgery is a challenging surgical subspecialty that requires highly specialized training and an adequate level of experience in order to be performed safely. As a result, minimally invasive HB surgery has been met with slower acceptance as compared to other subspecialties, with many surgeons in the ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-013-2276-2
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:The manifestations associated with non-survival after multiple trauma may vary importantly between countries and institutions. The aim of the present study was to assess the quality of performance by comparing actual mortality rates to the literature. METHODS:The study involved evaluation of a prospective c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0193-1
更新日期：2009-11-01 00:00:00
abstract：OBJECTIVE:To evaluate comparative outcomes of laparoscopic transcystic (TC) and transductal (TD) common bile duct (CBD) exploration. METHODS:We systematically searched MEDLINE, EMBASE, CINAHL, CENTRAL, the World Health Organization International Clinical Trials Registry, ClinicalTrials.gov, ISRCTN Register, and biblio...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析
doi：10.1007/s00268-019-05005-y
更新日期：2019-08-01 00:00:00
abstract：:Open gastric surgery in elderly patients is associated with higher morbidity and mortality rates than those reported among younger individuals. Therefore, minimally invasive surgery may have a larger impact on the elderly compared to the younger age group. The objective of this study was to evaluate the experience of ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0208-5
更新日期：2005-12-01 00:00:00
abstract：:With limited resources and the current concerns about using animals for research purposes, the needs must be clear when setting up trauma and sepsis experiments for pharmacologic interventions. Such interventions are performed typically for four reasons: (1) to study the pathophysiologic role of certain mediators (whi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900077
更新日期：1996-05-01 00:00:00
abstract：BACKGROUND:The albumin-bilirubin (ALBI) score was initially developed for assessing liver dysfunction severity and was suggested to have prognostic value in patients with hepatocellular carcinoma. We aimed to evaluate the prognostic impact of ALBI grade in patients with advanced gastric cancer (GC) after radical gastre...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4234-x
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:Pilonidal sinus is a common chronic disease affecting young adults. Many surgical procedures have been developed for its treatment, but an optimal one has still not been achieved. This study presents a modification to the Karydakis operation. METHODS:A total of 265 patients with chronic pilonidal sinus betw...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4406-8
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:There is a paucity of data on the presentation and surgical management of pheochromocytoma in developing nations, particularly in Africa. METHODS:This study was a retrospective review, which included all patients managed by the Groote Schuur Hospital/University of Cape Town Endocrine Surgery unit for pheoch...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05420-6
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the available resources for trauma care at health centers (HCs) and referral hospitals (RHs) in rural Cambodia and to examine whether the resources at HCs are allocated on the basis of actual need based on the referral distance and number of severely injured patients ref...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9900-6
更新日期：2009-04-01 00:00:00
abstract：:Individuals in clinical training programs concerned with critical medical care must learn to manage clinical cases effectively as a member of a team. However, practice on live patients is often unpredictable and frequently repetitive. The widely substituted alternative for real patients-high-fidelity, manikin-based si...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9354-2
更新日期：2008-02-01 00:00:00
abstract：BACKGROUND:Laparoscopic intersphincteric resection (ISR) after neoadjuvant chemoradiation is helpful in the management of patients with low rectal cancer. With the advent of this technique, the need for performance of abdominoperineal resection seems to have decreased in patients with very low rectal tumors. The aim of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1277-2
更新日期：2011-12-01 00:00:00
abstract：:Enteral nutrition (EN) and total parenteral nutrition (TPN) may provide life-sustaining therapy for surgical patients. The duration of nutritional therapy (enteral or parenteral) implies distinct access routes. We review the main aspects related to access routes for nutrient delivery. The enteral route, whenever feasi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010264
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Because the feasibility and safety of laparoscopic approaches for the treatment of perforated peptic ulcer (PPU) have been fully recognized, laparoscopic repair of PPU (LPPU) has become a widely accepted procedure. Following closure of a PPU, the rationale to add an omental patch is based on the assumptions ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2503-5
更新日期：2014-08-01 00:00:00
abstract：BACKGROUND:Strictures at the pharyngoesophageal junction represent a subgroup of corrosive esophageal strictures requiring a specialized management approach. Non-dilatable cricopharyngeal strictures need surgical intervention. We report the use of the sternocleidomastoid muscle myocutaneous inlay flap (SCMMIF) for reco...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9120-5
更新日期：2007-08-01 00:00:00
abstract：BACKGROUND:Surgical treatment of amiodarone-associated thyrotoxicosis (AAT) is effective although fewer than 100 cases have been reported world wide. MATERIALS AND METHODS:We reviewed 14 patients treated with total thyroidectomy by a single surgeon from 1998 to 2005. RESULTS:There were 11 male and 3 female patients w...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0673-x
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS:Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have un...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1851-2
更新日期：2013-03-01 00:00:00
abstract：:Knowledge of lymphatic involvement in patients with colorectal cancer is important in surgery and in the postoperative decision-making process. Fifty-eight patients with recurrent colorectal cancer underwent operation with the RIGS/(Radioimmunoguided Surgery) technology. Preoperatively, patients were injected with 1 m...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0158-5
更新日期：2001-12-01 00:00:00
abstract：BACKGROUND:Increasing numbers of patients are treated by robotic distal gastrectomy (RDG); however, it remains unclear whether RDG is clinically comparable with conventional laparoscopic distal gastrectomy (LDG). This study aimed to clarify the feasibility of RDG from safety aspects. METHODS:The study included 109 cT1...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4345-4
更新日期：2018-06-01 00:00:00
abstract：:Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067089
更新日期：1992-11-01 00:00:00
abstract：BACKGROUND:Gastrointestinal (GI) tract perforation during endoscopy is a rare but severe complication. The aim of this study was to determine predictors of morbidity and mortality after iatrogenic endoscopic perforation. MATERIALS AND METHODS:All cases with iatrogenic endoscopic perforation receiving surgery at a tert...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-3986-7
更新日期：2017-08-01 00:00:00
abstract：BACKGROUND:Sepsis is common in surgical patients, and its presence influences the outcomes in those to undergo surgery. Factors such as advanced age, presence of comorbidities and many other conditions increase mortality in surgical patients with sepsis. The sequential organ failure assessment (SOFA) score simplified i...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05708-7
更新日期：2020-11-01 00:00:00
abstract：PURPOSE:Advanced Trauma Life Support (ATLS®) is one of the world's best-known training programs for medical providers. Revisions of the ATLS manual have been evidence based for a number of years. In 2011, a level 3 (S3) evidence- and consensus-based guideline on the treatment of patients with severe and multiple injuri...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3063-z
更新日期：2015-08-01 00:00:00
abstract：:Octenidine HCl is new topical antiseptic solution for wounds and abdominal washing that has been found to be highly effective for inactivating scolices in an in vitro study. However, the effects of octenidine HCl on the liver are not yet known. The aim of this study was to determine if there are any histopathologic ch...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9022-6
更新日期：2007-06-01 00:00:00
abstract：:Sixty-one patients who were diagnosed with mucosal gastric cancer have been successfully treated with two laparoscopic techniques at our institute from March 1992 to March 1997. One is laparoscopic wedge resection of the stomach using a lesion-lifting method for lesions of the anterior wall, the lesser curvature, and ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00013167
更新日期：1999-02-01 00:00:00
abstract：BACKGROUND:The evolution of diagnostic procedures has resulted in an increase in early detection of pathologically T1 (pT1) colorectal cancer (CRC). However, the risk factors affecting long-term outcomes of patients with pT1 CRCs have been unclear. The aim of the present study was to identify risk factors for postopera...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1378-y
更新日期：2012-02-01 00:00:00
abstract：OBJECTIVE:Radical lymph node dissection (LND) along the bilateral recurrent laryngeal nerve (RLN) is a surgically challenging procedure with a high rate of morbidity. Here, we assessed in a retrospective manner the adequacy of LND along the RLN performed with robot-assisted thoracoscopic esophagectomy (RATE) versus vid...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4179-0
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Over the past decade, assessments of surgical capacity in low- and middle-income countries (LMICs) have contributed to our understanding of barriers to the delivery of surgical services in a number of countries. It is yet unclear, however, how the findings of these assessments have been applied and built upo...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-014-2938-8
更新日期：2015-04-01 00:00:00
abstract：:Angiogenesis is essential for tumor growth and metastasis. An association between microvessel density, a measure of tumor angiogenesis, and conventional prognostic variables has been shown for many tumor entities. For Barrett's carcinoma, the results are controversial. Immature vessels formed in tumors are structurall...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7286-7
更新日期：2004-07-01 00:00:00
abstract：BACKGROUND:The aim of this study was to compare single-port access cholecystectomy (SPA) with the standard laparoscopic technique (LC) regarding the duration of the operation, complications, learning curve, late postoperative quality of life (QoL) and the incidence of incisional hernias. METHODS:Between June 2009 and ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s00268-013-1946-4
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:The Laboratory Risk Indicator for Necrotizing Fasciitis (LRINEC) scoring system was developed to aid the diagnosis of necrotizing fasciitis and guide management [1]. AIM:To validate the LRINEC score and identify clinical predictors to develop a refined diagnostic scoring tool for the diagnosis of necrotizin...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05061-4
更新日期：2019-10-01 00:00:00
