Surgery for Pheochromocytoma: A Single-Center Review of 60 Cases from South Africa.


BACKGROUND:There is a paucity of data on the presentation and surgical management of pheochromocytoma in developing nations, particularly in Africa. METHODS:This study was a retrospective review, which included all patients managed by the Groote Schuur Hospital/University of Cape Town Endocrine Surgery unit for pheochromocytoma and abdominal paragangliomas, from January 2002 to June 2019. RESULTS:Sixty patients were included in the study, of which 33% were male and 67% female. The mean age was 47 years (range 14-81). The median tumor size was 6 cm, with 45% larger than 6 cm. 92% were located in the adrenal gland (87% unilateral, 5% bilateral), and 8% were extra-adrenal. The conversion rate for laparoscopic cases was 20%, with 55% of cases overall completed laparoscopically. Eleven patients with tumors > 6 cm were initially attempted laparoscopically, of which 3 were converted to open, without any associated increased morbidity. A major adverse event was recorded for 5 cases (8%), including 1 mortality. Overall morbidity, blood loss, operating time and hospital stay were all significantly reduced in the laparoscopic group. There were 5 patients with malignant disease (8%). CONCLUSION:This large series, from an established academic endocrine surgery unit in Africa, can serve as a benchmark for units with similar settings and resource limitations, to compare their surgical management and perioperative outcomes.


World J Surg


World journal of surgery


Nel D,Panieri E,Malherbe F,Steyn R,Cairncross L




Has Abstract


2020-06-01 00:00:00














  • Hepatectomy for colorectal liver metastases with macroscopic intrabiliary tumor growth.

    abstract:OBJECTIVES:We set out to clarify the clinicopathologic characteristics of colorectal liver metastases with macroscopic intrabiliary tumor growth and to determine optimal surgical management. METHODS:Over 15 years, 6 of 103 patients undergoing hepatectomy for colorectal liver metastases had macroscopic intrabiliary tum...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sugiura T,Nagino M,Oda K,Ebata T,Nishio H,Arai T,Nimura Y

    更新日期:2006-10-01 00:00:00

  • Metastatic tumor doubling time: most important prehepatectomy predictor of survival and nonrecurrence of hepatic colorectal cancer metastasis.

    abstract::We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Tanaka K,Shimada H,Miura M,Fujii Y,Yamaguchi S,Endo I,Sekido H,Togo S,Ike H

    更新日期:2004-03-01 00:00:00

  • Economic modeling of surgical disease: a measure of public health interventions.

    abstract::The measurement of the burden of disease and the interventions that address that burden can be done in various units. Reducing these measures to the common denominator of economic units (i.e., currency) enables comparison with other health entities, interventions, and even other fields. Economic assessment is complex,...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Corlew DS

    更新日期:2013-07-01 00:00:00

  • Herniography.

    abstract::Herniographic examinations were performed on more than 4,000 patients. The method was found to be of great value in patients with obscure symptoms in the groin or pelvis. Herniography shows not only hernial sacs but also the general condition and tissue strength of the inguinal part of the abdominal wall. The differen...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Gullmo A

    更新日期:1989-09-01 00:00:00

  • Risk Factors for Postoperative Ascites in Patients Undergoing Liver Resection for Hepatocellular Carcinoma.

    abstract:BACKGROUND:Postoperative ascites is a common complication after liver resection. This study aimed to identify the risk factors for ascites in patients after liver resection and the relationship between postoperative ascites and other complications. METHODS:We retrospectively analyzed data that were obtained from 266 p...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Yoshikawa T,Nomi T,Hokuto D,Yasuda S,Kawaguchi C,Yamada T,Kanehiro H,Nakajima Y

    更新日期:2017-08-01 00:00:00

  • Implementation Analysis of a Perioperative Patient Safety Program in Guatemala.

    abstract:BACKGROUND:The implementation of programs to improve patient safety remains challenging in low- and middle-income countries. The goal of our study was to define the barriers and facilitators to implementation of a perioperative patient safety program in Guatemala. MATERIAL AND METHODS:We conducted semi-structured inte...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Sico IP,Hall BJ,Aguilar-González A,Orozco M,Ramirez C,Baumgartner JN,Boyd D,Bolaños J,Calgua E,Lou-Meda R,Rice HE

    更新日期:2020-07-01 00:00:00

  • Laparoscopic Versus Open Cholecystectomy: A Cost-Effectiveness Analysis at Rwanda Military Hospital.

    abstract:BACKGROUND:Laparoscopic cholecystectomy is first-line treatment for uncomplicated gallstone disease in high-income countries due to benefits such as shorter hospital stays, reduced morbidity, more rapid return to work, and lower mortality as well-being considered cost-effective. However, there persists a lack of uptake...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Silverstein A,Costas-Chavarri A,Gakwaya MR,Lule J,Mukhopadhyay S,Meara JG,Shrime MG

    更新日期:2017-05-01 00:00:00

  • Segment III cholangiojejunostomy for carcinoma of the gallbladder.

    abstract::Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Chaudhary A,Dhar P,Tomey S,Sachdev A,Agarwal A

    更新日期:1997-10-01 00:00:00

  • Electrocoagulation for adenocarcinoma of the low rectum.

    abstract::Cancers of the distal rectum (less than 7.5 cm from the anal verge) that are freely mobile, moderately well or well differentiated, less than 4 cm in size, limited to the bowel wall, and without evidence of metastasis should be considered candidates for treatment with electrocoagulation for cure. Tumor cell ploidy and...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: Eisenstat TE,Oliver GC

    更新日期:1992-05-01 00:00:00

  • Loop ileostomy closure: comparison of cost effectiveness between suture and stapler.

    abstract:BACKGROUND:Closure of loop ileostomy can be safely performed using sutures or staplers. The aim of the present study was to compare the cost effectiveness of three different techniques. METHODS:A total of 128 consecutive patients who underwent closure of loop ileostomy between January 2002 and December 2008 were analy...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Horisberger K,Beldi G,Candinas D

    更新日期:2010-12-01 00:00:00

  • Selective nonoperative management of kidney gunshot injuries.

    abstract:BACKGROUND:Nonoperative management (NOM) of kidney gunshot injuries as an alternative to surgical exploration is rarely reported. The aim of this study was to assess the feasibility and safety of selective NOM of such injuries. METHODS:A 4-year prospective study was conducted that included all patients admitted to a L...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Navsaria PH,Nicol AJ

    更新日期:2009-03-01 00:00:00

  • Management of mycobacterial cervical lymphadenitis.

    abstract::The treatment results of mycobacterial cervical lymphadenitis in 69 patients between 1990 and 1993 are reviewed. All patients underwent surgical procedures consisting of total excision or selective nodal dissection for lymphadenopathies and curettage for fluctuant cases, followed by antituberculous chemotherapy applie...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Kanlikama M,Gökalp A

    更新日期:1997-06-01 00:00:00

  • Pre-operative radiotherapy prolongs survival in operable esophageal carcinoma: a randomized, multicenter study of pre-operative radiotherapy and chemotherapy. The second Scandinavian trial in esophageal cancer.

    abstract::In a prospective multicenter study, 186 patients with squamous cell esophageal carcinoma, who after evaluation were considered suitable for surgery, were randomized to 4 treatment groups: Group 1, surgery alone; Group 2, pre-operative chemotherapy (cisplatin and bleomycin) and surgery; Group 3, pre-operative irradiati...

    journal_title:World journal of surgery

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验


    authors: Nygaard K,Hagen S,Hansen HS,Hatlevoll R,Hultborn R,Jakobsen A,Mäntyla M,Modig H,Munck-Wikland E,Rosengren B

    更新日期:1992-11-01 00:00:00

  • Impact of transjugular intrahepatic portosystemic shunt on orthotopic liver transplantation.

    abstract::Transjugular intrahepatic portosystemic shunt (TIPS) is being increasingly utilized prior to liver transplantation for portal hypertensive bleeding refractory to sclerotherapy or as initial management of variceal bleeding. The impact of TIPS on subsequent orthotopic liver transplantation (OLT) is uncertain. The purpos...

    journal_title:World journal of surgery

    pub_type: 临床试验,杂志文章


    authors: Menegaux F,Baker E,Keeffe EB,Monge H,Egawa H,Esquivel CO

    更新日期:1994-11-01 00:00:00

  • A case-control study of single-incision versus standard laparoscopic cholecystectomy.

    abstract:BACKGROUND:Single-incision laparoscopic cholecystectomy (SILC) has been increasingly performed recently. Although it seems plausible that SILC will be associated with less pain compared to standard 4-port laparoscopic cholecystectomy (LC), there is currently no conclusive comparative study on the postoperative pain iss...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Chang SK,Tay CW,Bicol RA,Lee YY,Madhavan K

    更新日期:2011-02-01 00:00:00

  • Evaluation of current devices in single-incision laparoscopic colorectal surgery: a preliminary experience in 32 consecutive cases.

    abstract:BACKGROUND:Single-incision laparoscopic colorectal surgery (SILS) suggests a promising alternative to conventional laparoscopic surgery. In this report we describe our initial experience with SILS for both right hemicolectomies and anterior resections. METHODS:Between June 2009 and May 2010, SILS was performed for 32 ...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Chew MH,Wong MT,Lim BY,Ng KH,Eu KW

    更新日期:2011-04-01 00:00:00

  • Micropuncture Access Set Use During Implantation of Totally Implantable Venous Access Device May Reduce Upper Extremity DVT Incidence Among Patients Undergoing Chemotherapy for Colorectal Cancer.

    abstract:BACKGROUND:The aim of this study was to compare the perioperative outcomes when using a micropuncture access set (MS) to those when using a conventional puncture set (CS) for implantation of totally implantable venous access device (TAVID). METHODS:A total of 314 patients undergoing chemotherapy for colorectal cancer ...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Lee CS,Yoon SH,Lee SM,Lee IK,Kim JY,Cho HM,Kim MK

    更新日期:2020-04-01 00:00:00

  • Clinical predictors of ongoing infection in secondary peritonitis: systematic review.

    abstract:INTRODUCTION:The decision to perform a relaparotomy in patients with secondary peritonitis is based on "clinical judgment" with inherent variability among surgeons. Our objective was to review the literature on prognostic variables for ongoing abdominal infection. Predictive variables for positive findings at relaparot...

    journal_title:World journal of surgery

    pub_type: 杂志文章,评审


    authors: Lamme B,Mahler CW,van Ruler O,Gouma DJ,Reitsma JB,Boermeester MA

    更新日期:2006-12-01 00:00:00

  • Clinicopathological study on carcinoma of the extrahepatic bile duct with special focus on cancer invasion on the surgical margins.

    abstract::To clarify the clinical significance of the status of surgical margins, especially the dissected margin in the transverse direction, a clinicopathologic study was performed on 60 patients with carcinoma of the bile duct who underwent radical resection. The patients in group A (n = 28) had no cancer invasion within 5 m...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Ogura Y,Takahashi K,Tabata M,Mizumoto R

    更新日期:1994-09-01 00:00:00

  • Acute Limb Ischemia Secondary to Native Artery Occlusion: Results of a Contemporary Case Series.

    abstract:BACKGROUND:The treatment of acute limb ischemia (ALI) has barely changed over the last years. However, the progressive implementation of anticoagulants, antiplatelet agents or statins within the population might have modified the profile and prognosis of patients suffering an ALI. The aim of this study was to evaluate ...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Seguí N,Ruiz-Carmona C,Velescu A,Mateos E,Elosua R,Clará A

    更新日期:2018-08-01 00:00:00

  • Adhesion-related complications are common, but rarely discussed in preoperative consent: a multicenter study.

    abstract:BACKGROUND:Peritoneal adhesions are recognized as an important cause for patient morbidity, but complications related to adhesions occur relatively late after the original operation. Therefore preoperative consent may not adequately reflect the proportions of the problem. METHODS:A total of 200 patients admitted for i...

    journal_title:World journal of surgery

    pub_type: 杂志文章,多中心研究


    authors: Rajab TK,Wallwiener M,Talukdar S,Kraemer B

    更新日期:2009-04-01 00:00:00

  • Surgical Training in South Africa: An Overview and Attempt to Assess the Training System from the Perspective of Foreign Trainees.

    abstract:BACKGROUND:Currently, there are no objective reports evaluating the quality of the South African surgical training. The aim of this study is to evaluate the current state of surgical training in South Africa from an external impartial point of view and to rate the experience of short-term supernumerary registrars and f...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Mantica G,Fransvea P,Virdis F,Hardcastle TC,Ackermann H,Terrone C,Costa G,Van der Merwe A,Balducci G,Steyn E

    更新日期:2019-09-01 00:00:00

  • Do hernia operations in african international cooperation programmes provide good quality?

    abstract:BACKGROUND:Hernia is especially prevalent in developing countries where the population is obliged to undertake strenuous work in order to survive, and International Cooperation Programmes are helping to solve this problem. However, the quality of surgical interventions is unknown. The objective of the present study was...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Gil J,Rodríguez JM,Hernández Q,Gil E,Balsalobre MD,González M,Torregrosa N,Verdú T,Alcaráz M,Parrilla P

    更新日期:2012-12-01 00:00:00

  • Taeniectomy Versus Transverse Coloplasty as Neorectum After Low Rectal Resection.

    abstract:PURPOSE:Restorative surgery for rectal cancer is usually criticized by its functional outcomes. The aim of this study is to assess the efficacy "taeniectomy" pouch in comparison with transverse coloplasty pouch. STUDY DESIGN:This was a prospective controlled study. Most patients who were candidate for low rectal resec...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Farag A,Mashhour AN,Elbarmelgi MY

    更新日期:2019-04-01 00:00:00

  • Genetic screening for MEN1 mutations in families presenting with familial primary hyperparathyroidism.

    abstract::A large number of families with familial isolated hyperparathyroidism (FIHP) have been reported. We wanted to determine if some of these families represent early manifestations of full-blown syndromes such as multiple endocrine neoplasia type 1 (MEN-1), as early identification may alter surgical and medical management...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Perrier ND,Villablanca A,Larsson C,Wong M,Ituarte P,Teh BT,Clark OH

    更新日期:2002-08-01 00:00:00

  • Perforation of jejunal diverticula in steroids and nonsteroidal anti-inflammatory drug abusers: a case series.

    abstract:INTRODUCTION:Jejunal diverticula are rare lesions, and when complications arise, they pose diagnostic difficulties. Perforation is a common complication resulting in an acute abdomen, although preoperative diagnosis is usually not possible. The "gold standard" for management for patients with complications is surgery. ...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Palanivelu C,Rangarajan M,Rajapandian S,Maheshkumaar GS,Madankumar MV

    更新日期:2008-07-01 00:00:00

  • Doxorubicin activity is enhanced by hyperthermia in a model of ex vivo vascular perfusion of human colon carcinoma.

    abstract::There is little information on the pharmacokinetics and pharmacodynamics of doxorubicin (DXR) administered during locoregional treatments of colon carcinoma under hyperthermic conditions. The aim of this study was to evaluate distribution and activity of DXR in healthy tissue and tumor tissues under hyperthermic condi...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Pilati P,Mocellin S,Rossi CR,Scalerta R,Alaggio R,Giacomelli L,Geroni C,Nitti D,Lise M

    更新日期:2003-06-01 00:00:00

  • Diaphragm myoplasty in the prevention of complications after surgery of hydatid disease of the liver.

    abstract::A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid disease of the liver by means of this alternative surgical technique....

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Dosios T,Kouraklis G,Karatzas G

    更新日期:2003-02-01 00:00:00

  • Prospective Risk Factor Analysis for the Development of Post-operative Urinary Retention Following Ambulatory General Surgery.

    abstract:AIMS:Post-operative urinary retention (POUR) is a common cause of unplanned admission following day-case surgery and has negative effects on both patient and surgical institution. We aimed to prospectively evaluate potential risk factors for the development of POUR following day-case general surgical procedures. METHO...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Scott AJ,Mason SE,Langdon AJ,Patel B,Mayer E,Moorthy K,Purkayastha S

    更新日期:2018-12-01 00:00:00

  • Risk factors contributing to a poor prognosis of papillary thyroid carcinoma: validity of UICC/AJCC TNM classification and stage grouping.

    abstract:BACKGROUND:In 2002, the UICC/AJCC TNM classification for papillary thyroid carcinoma was revised. In this study, we examined the validity of this classification system by investigating the predictors of disease-free survival (DFS) and cause-specific survival (CSS) in patients. METHODS:We examined various clinicopathol...

    journal_title:World journal of surgery

    pub_type: 杂志文章


    authors: Ito Y,Miyauchi A,Jikuzono T,Higashiyama T,Takamura Y,Miya A,Kobayashi K,Matsuzuka F,Ichihara K,Kuma K

    更新日期:2007-04-01 00:00:00