Abstract:
BACKGROUND:Adhesions due to the reactions caused by the grafts used in primary vascular operations can lead to various problems when a secondary operation is necessary. These problems include bleeding, injuries to neighboring organs, and complications occurring due to a prolonged operation. We investigated the effects of sirolimus, which has antiproliferative features, on vascular adhesions. METHODS:The abdominal aorta of rats was explored and abrasions applied. Following the fixation of a polytetrafluoroethylene (PTFE) graft on the abdominal aorta, sirolimus (rapamycin) is applied (in powdered form) onto the grafts of the study group. Eight weeks later a laparotomy was repeated and any adhesions were evaluated. RESULTS:In the study group the adhesions were determined to be fewer in number and milder in severity. Severe cases of adhesion were determined in the control group. CONCLUSIONS:Therefore, sirolimus applied around the prosthesis in vascular operations was determined to be effective at preventing possible adhesions.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Kanko M,Ozbudak E,Ozerdem A,Aksoy A,Kilic M,Berki KTdoi
10.1007/s00268-005-0750-1subject
Has Abstractpub_date
2006-09-01 00:00:00pages
1648-52issue
9eissn
0364-2313issn
1432-2323journal_volume
30pub_type
杂志文章abstract:BACKGROUND:The objective of this study was to compare the prevalence of Helicobacter pylori (HP) seropositivity in patients undergoing bariatric surgery with that of the general population. METHODS:H. pylori serologies, tested by ELISA, were collected on 240 morbidly obese patients seen at the Cleveland Clinic Florida...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9608-7
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:When needle core biopsies (NCBs) of the breast reveal fibroepithelial lesions (FELs), excision is often performed to rule out a phyllodes tumor (PT), despite low malignancy rates. Consequently, the natural history of observed FELs is not well described. We analyzed the malignancy risk in excised FELs and the...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05385-6
更新日期:2020-05-01 00:00:00
abstract::Little evidence is available regarding long-term survival of patients with gallbladder cancer that is discovered at the time of laparoscopic cholecystectomy (LC). Therefore the present study was performed to evaluate long-term outcomes of this disease. Of 1546 patients who underwent LC for benign gallbladder disease b...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7886-x
更新日期:2005-09-01 00:00:00
abstract:BACKGROUND:Up to 50% of patients in intensive care units develop intraabdominal hypertension (IAH) in the course of medical treatment. If not detected on time and treated adequately, IAH may develop into an abdominal compartment syndrome (ACS) which is associated with a high mortality rate. Patients undergoing cardiac ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05917-0
更新日期:2021-01-22 00:00:00
abstract:BACKGROUND:This is the fourth updated Enhanced Recovery After Surgery (ERAS®) Society guideline presenting a consensus for optimal perioperative care in colorectal surgery and providing graded recommendations for each ERAS item within the ERAS® protocol. METHODS:A wide database search on English literature publication...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-018-4844-y
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:It has been suggested that gender and age could be factors that influence the likelihood of success following antireflux surgery, and our anecdotal impression has been that the outcome following Nissen fundoplication in older women is often disappointing. If correct, characterization of the extent of any dif...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0216-y
更新日期:2009-12-01 00:00:00
abstract:BACKGROUND:Schistosomiasis is a waterborne trematode with numerous subtypes affecting different areas of the body. Rob Ferreira Hospital is located in an endemic area for schistosomiasis in the Lowveld region of South Africa. We set out to determine the prevalence of Sch istosoma in appendicitis. METHODS:From 2009 to ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-2954-3
更新日期:2015-05-01 00:00:00
abstract:BACKGROUND:Recent studies have shown a 7-15% lymph node (LN) metastasis rate in submucosal invasive colorectal cancer (SICC). Identifying risk factors for LN metastasis is crucial in selecting therapeutic modalities for SICC. We assessed the possibility of and the risk factors for LN metastasis in SICC. METHODS:We per...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9628-3
更新日期:2008-09-01 00:00:00
abstract:BACKGROUND:Patients with stage II colorectal cancer (CRC) have a higher risk of recurrence when they have certain risk factors, including clinical and pathological patterns. However, as the prognostic role of molecular patterns for stage II disease is still unclear, this study aimed to investigate it. METHODS:A total ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05158-w
更新日期:2019-12-01 00:00:00
abstract:BACKGROUND:The survival impact of distal pancreatectomy (DP) with celiac axis resection for locally advanced pancreatic body/tail cancer remains unclear. METHODS:A total of 16 patients underwent DP with celiac axis resection, while 76 underwent standard DP for pancreatic body/tail cancer. The indications for DP with c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3670-3
更新日期:2017-01-01 00:00:00
abstract:INTRODUCTION:The association between socioeconomic status (SES) and relative survival of rectal cancer is little investigated. We hypothesized that the impact on risk of death by SES would be much smaller when differences in background mortality (comorbidity, lifestyle factors) were taken into account, i.e. in modellin...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2735-4
更新日期:2014-12-01 00:00:00
abstract::Previous analysis of this prospective randomized trial and meta-analysis of published randomized trials of adjuvant intraperitoneal chemotherapy demonstrated improved survival in patients with advanced gastric cancer. Simple criteria applicable at the time of surgery for patient selection were sought in this analysis....
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s00268-001-0067-7
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:The goal of this study was to evaluate the outcome of patients who had the Nuss procedure for repair of pectus excavatum. METHODS:Thirty-nine patients (26 male, 13 female) of 61 (63.9%) who had bar removal after the Nuss procedure agreed to participate in an interview. All patients and their parents were as...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1111-x
更新日期:2011-07-01 00:00:00
abstract::Although most papillary thyroid microcarcinomas (PMCs) are of little clinical significance, patients with PMCs occasionally have an unfavorable outcome, especially when they present with bulky nodal metastasis or distant metastasis. We have attempted to identify "high-risk" PMCs by evaluating clinical, pathologic, and...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900461
更新日期:1998-07-01 00:00:00
abstract:BACKGROUND:Surgical 'never events' have serious adverse outcomes for patients. A never event can be defined as a serious, avoidable patient safety incident that would not occur if necessary preventative measures are implemented. The literature from South Africa on this topic is limited. This study aims to understand th...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05008-9
更新日期:2019-09-01 00:00:00
abstract::Expression of sialyl-Lewisx (sLex) antigen was studied immunohistochemically in 110 resected human gastric carcinomas using an anti-sLex monoclonal antibody. Lymph node, liver, and peritoneal metastases were clearly more prevalent in tumors expressing high levels of sLex than in those with no or low-level sLex express...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900304
更新日期:1997-09-01 00:00:00
abstract:BACKGROUND:Peritoneal adhesions are recognized as an important cause for patient morbidity, but complications related to adhesions occur relatively late after the original operation. Therefore preoperative consent may not adequately reflect the proportions of the problem. METHODS:A total of 200 patients admitted for i...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-008-9917-x
更新日期:2009-04-01 00:00:00
abstract:INTRODUCTION:In India, half of the annual 200,000 road traffic deaths occur in hospitals, but the exact in-hospital trauma mortality rate remains unknown. A research consortium of universities, with a mandate to reduce trauma mortality, measured the baseline 30-day in-hospital mortality rate. METHODS:Between September...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-016-3452-y
更新日期:2016-06-01 00:00:00
abstract::The aim of the present study was to determine whether patients with the incident hospital diagnosis of primary hyperparathyroidism (PHPT) in Denmark during the period 1977-1993 had an increased mortality from cardiovascular disease and cancer compared to the rest of the Danish population. In a random sample of half of...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7046-0
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:Medullary thyroid cancer (MTC) is characterized by early regional lymph node metastasis, the presence of which represents a critical obstacle to cure. At present no molecular markers have been successfully integrated into the clinical care of sporadic MTC. The present study was designed to evaluate TP53INP1 ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0395-6
更新日期:2010-04-01 00:00:00
abstract::To illustrate how the high incidence of arrow wounds provided a major stimulus for the development of surgery until a century ago, we conducted a literature search. Our research shows that archaic peoples developed considerable surgical skill for extraction of arrows, including thoracotomy and trephination. A classica...
journal_title:World journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1007/s00268-001-0168-3
更新日期:2001-12-01 00:00:00
abstract:BACKGROUND:Few studies in the literature have reported recovery data for different types of recurrent laryngeal nerve injuries (RLNIs). This study is the first attempt to classify RLNIs and rank them by severity. METHODS:This prospective clinical study analyzed 281 RLNIs in which a true loss of signal was identified b...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3415-3
更新日期:2016-06-01 00:00:00
abstract:BACKGROUND:Small bowel obstruction (SBO) is characterized by a high rate of recurrence. In the present study, we aimed to compare the outcomes of patients managed either by conservative treatment or surgical operation for an episode of SBO. METHODS:The outcomes of all patients hospitalized at a single center for acute...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2733-6
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:It is now generally believed that regulatory T cells (Tregs) play an important role in peripheral tolerance, and a defect in Tregs is considered one of the most important factors in the induction of various kinds of autoimmune disease including ulcerative colitis (UC). Here, we examined the change in frequen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0301-9
更新日期:2006-04-01 00:00:00
abstract::Although palpable axillary lymphadenopathy is most often related to benign disorders, it may be a harbinger of an underlying advanced malignancy. Fewer than 1% of patients diagnosed with breast cancer initially present with axillary metastases as their only clinical manifestation. This study represents the Mayo Clinic...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7290-y
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Five billion people lack access to surgery. Accurate and complete data have been identified as essential to the global scale-up of perioperative care. This study retrospectively validates the Mbarara Surgical Services Quality Assurance Database (SQUAD), an electronic outcomes database at a Ugandan secondary ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05537-8
更新日期:2020-08-01 00:00:00
abstract::Despite a slow decline in the incidence of gastric cancer over the last 90 years, we can still expect to see over 100,000 patients die of this disease each decade in England and Wales. The 5-year survival rate has not improved during this century, which is largely due to the stage at diagnosis being unchanged. There a...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00294709
更新日期:1995-07-01 00:00:00
abstract:BACKGROUND:Over the past decade, assessments of surgical capacity in low- and middle-income countries (LMICs) have contributed to our understanding of barriers to the delivery of surgical services in a number of countries. It is yet unclear, however, how the findings of these assessments have been applied and built upo...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-014-2938-8
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:This study aims to determine the prevalence and predictive factors for recurrence after sentinel lymph node biopsy (SLNB) and for sentinel lymph node positivity by SLNB in our population. METHODS:We followed up all SLNBs performed between 2002 and 2010 and analyzed data by R (version2.10.1), considering p <...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1420-0
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Patients with hepatocellular carcinoma (HCC) who underwent hepatectomy often developed an intrahepatic recurrence, even though it was a curative one. The relationship between surgery-induced liver damage and the recurrence of HCC has not been described. This study evaluated whether posthepatectomy liver fail...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2247-7
更新日期:2014-01-01 00:00:00