Abstract：
BACKGROUND:Recent studies have shown a 7-15% lymph node (LN) metastasis rate in submucosal invasive colorectal cancer (SICC). Identifying risk factors for LN metastasis is crucial in selecting therapeutic modalities for SICC. We assessed the possibility of and the risk factors for LN metastasis in SICC. METHODS:We performed a retrospective study on 168 SICC patients who underwent curative resection between June 1989 and December 2004 at Asan Medical Center. The level of submucosal invasion was classified into upper third (sm1), middle third (sm2), and lower third (sm3). The following carcinoma-related variables were assessed: tumor size, tumor location, depth of submucosal invasion, cell differentiation, lymphovascular invasion, neural invasion, and tumor cell dissociation (TCD). RESULTS:The overall LN metastasis rate was 14.3%. Significant predictors of LN metastasis both univariately and multivariately were sm3 (p = 0.039), poorly differentiated cancer (p = 0.028), and TCD (p = 0.045). Lymphovascular invasion was a risk factor for LN metastasis in univariate analysis (p = 0.019); however, in multivariate analysis, lymphovascular invasion could not predict LN metastasis. No statistical difference was observed in the risk of LN metastasis with regard to tumor location, size, and neural invasion. CONCLUSION:The depth of submucosal invasion, cell differentiation, and tumor cell dissociation were significant pathologic predictors of LN metastasis in SICC. Because SICC is associated with a considerable risk of LN metastasis, local excision may be performed carefully in SICC without adverse features.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Choi PW,Yu CS,Jang SJ,Jung SH,Kim HC,Kim JCdoi
10.1007/s00268-008-9628-3subject
Has Abstractpub_date
2008-09-01 00:00:00pages
2089-94issue
9eissn
0364-2313issn
1432-2323journal_volume
32pub_type
杂志文章abstract：:Individuals in clinical training programs concerned with critical medical care must learn to manage clinical cases effectively as a member of a team. However, practice on live patients is often unpredictable and frequently repetitive. The widely substituted alternative for real patients-high-fidelity, manikin-based si...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9354-2
更新日期：2008-02-01 00:00:00
abstract：:Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900319
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:Fast-track surgery (FTS) is a promising program for surgical patients and has been applied to several surgical diseases. FTS is much superior to conventional perioperative care. Our aim was to evaluate and compare the safety and efficacy of FTS and conventional perioperative care for patients undergoing gast...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-014-2690-0
更新日期：2014-12-01 00:00:00
abstract：:Patients with obstructive jaundice (OJ) that requires surgery often have malnutrition associated with increased perioperative morbidity. This study investigated the factors influencing nutritional derangements in these patients. A series of 46 OJ patients were investigated prospectively (28 malignant tumors, 18 benign...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020043
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:The change in the route of food passage after pancreaticoduodenectomy (PD) is quite similar to the change after gastric bypass surgery; both procedures bypass the duodenum and directly connect to the distal jejunum. Moreover, both procedures result in resolution of type 2 diabetes mellitus. Therefore, more d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3157-7
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Reported results of incisional hernia repair are poor with high recurrence rates unless prosthetic mesh is used. Mesh gives improved results, but certain techniques are associated with a high incidence of infections, fistulas, and seromas. This study reports the results of a consecutive series of incisional ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9118-z
更新日期：2008-01-01 00:00:00
abstract：:Resection remains the treatment of choice in liver cancer. In order to avoid liver transplantation in conventionally unresectable tumors ex-situ ("bench" procedure), in-situ and ante-situm resection technique should be preferred whenever feasible. Despite the deficiency of donor organs, a single center experience with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00299775
更新日期：1995-11-01 00:00:00
abstract：BACKGROUND:Schistosomiasis is a waterborne trematode with numerous subtypes affecting different areas of the body. Rob Ferreira Hospital is located in an endemic area for schistosomiasis in the Lowveld region of South Africa. We set out to determine the prevalence of Sch istosoma in appendicitis. METHODS:From 2009 to ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2954-3
更新日期：2015-05-01 00:00:00
abstract：:The aim of this study was to identify the risk factors for bacterial translocation and to determine the clinical significance of bacterial translocation in patients with colorectal cancer. Mesenteric lymph node sampling was performed to identify the presence of bacterial translocation in 75 patients with colorectal ca...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7576-0
更新日期：2005-02-01 00:00:00
abstract：INTRODUCTION:Sentinel lymph node biopsy (SLNB) is the standard of care for staging N0 primary early breast cancers (EBC). Patients in developing countries mostly present with large (LOBC) or locally advanced cancers (LABC) and are treated with neo-adjuvant chemotherapy (NACT). Accuracy of SLNB in staging stage III N0 a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3222-2
更新日期：2016-07-01 00:00:00
abstract：:A total of 143 patients who underwent hepatic resection for hepatocellular carcinoma in our department were reviewed. The review was conducted for two periods: 1970-1982 (early period) and 1983-1990 (late period), that is, the periods before and after introduction of the hepatic surgical technique involving the use of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01659138
更新日期：1993-09-01 00:00:00
abstract：:Radiologically demonstrable pancreatic endocrine tumors are a frequent requirement for exploration in patients with multiple endocrine neoplasia type I (MEN-I). Such delayed intervention is accompanied by a 30% to 50% incidence of pancreatic endocrine metastases. This study explores biochemical tumor markers and opera...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900451
更新日期：1998-07-01 00:00:00
abstract：BACKGROUND:To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS:Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have un...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1851-2
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Trauma in the elderly (≥ 55 years) accounts for a significant proportion of admissions to trauma centers. Our understanding of the epidemiology and outcomes associated with penetrating injury in this age segment of the population, however, is severely limited. The aim of the present study therefore was to in...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0920-7
更新日期：2011-03-01 00:00:00
abstract：:The pathogenesis of pain in chronic pancreatitis remains an enigma. The cause of pain is almost certainly multifactorial and may vary at different stages of the disease process. These factors may include the release of excessive oxygen-derived free radicals, tissue hypoxia and acidosis, inflammatory infiltration with ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-003-7235-x
更新日期：2003-11-01 00:00:00
abstract：BACKGROUND:Finnmark County is the northernmost county in Norway. For several decades, the rate of mortality after injury in this sparsely inhabited region has remained above the national average. Following documentation of this discrepancy for the period 1991-1995, improvements to the trauma system were implemented. Th...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1102-y
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:The incidence of thyroid cancer is increasing globally. This is mainly due to the increase in the detection of small papillary carcinomas, including papillary microcarcinomas (PMC) 1 cm or smaller. It was suggested recently that PMCs are overdiagnosed and overtreated. METHODS:In 1993, the author proposed a ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3392-y
更新日期：2016-03-01 00:00:00
abstract：:We analyzed clinical features and genetic alterations in the noncancerous and cancerous biliary lesions obtained from pancreaticobiliary maljunction (PBM) patients. Gallbladder (GB) and bile duct (BD) lesions were obtained surgically from 36 patients with PBM, and polymerase chain reaction (PCR) methods were used to e...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0187-0
更新日期：2002-01-01 00:00:00
abstract：:From January, 1972 to June, 1989, 51 patients with liver hemangiomas (32 females and 19 males, mean age 35 years) were evaluated for surgical treatment. Diameters of the masses were 5 cm to 20 cm (median 8.5 cm). Nine of the patients had already been treated for cancer. Twenty-two (43.1%) of the 51 patients were sympt...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02104457
更新日期：1992-05-01 00:00:00
abstract：:The post-Soviet calamities of East European cardiac surgery highlight the spectrum of marked differences in overall operative capacities among individual post-Communist countries. A comparison with the level of cardiac surgery in Western Europe reveals the importance of continuing relief, comprising both educational a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7103-8
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Never events (NEs) are serious clinical incidents that cause potentially avoidable harm and impose a significant financial burden on healthcare systems. The purpose of this study was to identify common never events. METHODS:We analysed the NHS England NE data from 2012 to 2020 to identify common never event...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05867-7
更新日期：2021-03-01 00:00:00
abstract：BACKGROUND:We reported phonatory recovery in the majority of 88 patients after recurrent laryngeal nerve (RLN) reconstruction. Here we analyzed factors that might influence the recovery, in a larger patient series. METHODS:At Kuma Hospital, 449 patients (354 females and 95 males) underwent RLN reconstruction with dire...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3634-7
更新日期：2016-12-01 00:00:00
abstract：:Clinical, endoscopic, and laboratory data were collected prospectively in 701 patients with bleeding peptic ulcer. The overall rebleeding rate was 16.1% and increased the risk of a fatal outcome by 17 fold (1.2% versus 20.6%, p less than 0.001). Rebleeding was documented in more than 75% of the group who did not survi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01664889
更新日期：1990-03-01 00:00:00
abstract：:Because of the rarity of adrenocortical carcinoma, survival rates and the prognosis for patients who have undergone operation are not well known. The purpose of the French Association of Endocrine Surgery was to evaluate these factors over an 18-year period. A trend study was associated to assess changes in the clinic...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0047-y
更新日期：2001-07-01 00:00:00
abstract：:The surgical treatment of 30 cases of vascular thoracic outlet syndrome (TOS) in 25 patients is presented. Patients included 17 women and 8 men with average age of 26.1 years. The causes of compression were cervical rib ( n = 16), soft tissue anomalies ( n = 12), and scar tissue after clavicle fracture ( n = 2). Ten s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6808-z
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Primary hyperparathyroidism (HPT) is often caused by a benign parathyroid tumor, adenoma; less commonly by multiglandular parathyroid disease/hyperplasia; and rarely by parathyroid carcinoma. Patients with multiple tumors require wider exploration to avoid recurrence and have increased risk for hereditary di...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-009-0022-6
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:Small bowel obstruction (SBO) is characterized by a high rate of recurrence. In the present study, we aimed to compare the outcomes of patients managed either by conservative treatment or surgical operation for an episode of SBO. METHODS:The outcomes of all patients hospitalized at a single center for acute...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2733-6
更新日期：2014-12-01 00:00:00
abstract：:Benign esophageal obstruction is virtually always responsive to dilation therapy. Dilation therapy should, therefore, be the initial approach. The introduction of the Savary-type dilating equipment and of balloon dilation systems are, or will become, standard practice. These systems will increasingly be preferred over...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658390
更新日期：1989-03-01 00:00:00
abstract：:We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7088-3
更新日期：2004-03-01 00:00:00
abstract：INTRODUCTION:Thyroid cancer (TC) incidence has been increasing in recent years. The aim of this study was to investigate our institution-based estimates of operative volumes for TC over the last three decades. MATERIALS AND METHODS:This was a retrospective cohort study of patients undergoing thyroid surgery at our ins...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3322-z
更新日期：2016-03-01 00:00:00
