Abstract:
:Clinical, endoscopic, and laboratory data were collected prospectively in 701 patients with bleeding peptic ulcer. The overall rebleeding rate was 16.1% and increased the risk of a fatal outcome by 17 fold (1.2% versus 20.6%, p less than 0.001). Rebleeding was documented in more than 75% of the group who did not survive following initial conservative management. Rebleeding was more likely (24.1% versus 14.2%, p less than 0.02) when shock was present on admission and the risk of a rebleed was doubled in patients over 60 years of age (22.1% versus 10.9%, p less than 0.001). Ulcers greater than 1 cm in size carried twice the risk of rebleeding (23.9% versus 12.4%, p less than 0.002). Concomitant medical illness had a significant adverse effect on outcome (p less than 0.05). Shock on admission was associated with a doubling of mortality figures (9.5% versus 3.7%, p less than 0.01). The identification of endoscopic stigmata of recent hemorrhage (ESRH) tripled the risk of mortality (7.5% versus 2.4%, p less than 0.002), ESRH were more frequently encountered when ulcer size was larger than 1 cm (61.4% versus 39.8%, p less than 0.001). Respective mortality rates for ulcers less than or equal to 1 cm and greater than 1 cm in size were 1.6% and 12.5% (p less than 0.001), corresponding mortality figures for patients over 60 years of age being 4.4% and 16.4% (p less than 0.002). The risk of a rebleed tripled (6.7% versus 2.6%, p less than 0.02) when ESRH were evident. There was a 6-fold increase in mortality following emergency surgery when compared with conservative management of patients in whom no surgical intervention was necessary (2.6% versus 14.9%, p less than 0.001). In summary, age over 60 years, previous medical illness, shock on admission, large ulcer size, and ESRH were each associated with an increased risk of rebleeding and mortality.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Branicki FJ,Coleman SY,Fok PJ,Pritchett CJ,Fan ST,Lai EC,Mok FP,Cheung WL,Lau PW,Tuen HHdoi
10.1007/BF01664889subject
Has Abstract,Author List Incompletepub_date
1990-03-01 00:00:00pages
262-9; discussion 269-70issue
2eissn
0364-2313issn
1432-2323journal_volume
14pub_type
杂志文章abstract:BACKGROUND:The stapled hemorrhoidopexy is reported to have a low recurrence while treating the major hemorrhoidal symptoms of bleeding and prolapse. The aim of this study is to obtain long-term results on the outcome of the stapled hemorrhoidopexy. METHODS:All patients with a hemorrhoidal disease grade III, who underw...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05065-0
更新日期:2019-10-01 00:00:00
abstract::Fourteen patients with liver tumor malignancy and sixteen patients with malignant melanoma localized to one limb were studied regarding leukocyte activation with the release of polymorphonuclear neutrophilic (PMN) elastase and of neopterin and formation of cytokines (TNF-alpha and IL-6) during the surgical treatment. ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF00299787
更新日期:1995-11-01 00:00:00
abstract:PURPOSE:Management of anal fistula represents a balance between curing the condition and maintaining anal continence. Recent reports of the results of the porcine anal fistula plug have demonstrated excellent fistula healing rates without reporting significant complications. METHODS:The outcome of patients who underwe...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9504-1
更新日期:2008-06-01 00:00:00
abstract::The role of liver transplantation in malignancy has been discussed, but controversially, over the past two decades. This is particularly true for hepatic metastases from neuroendocrine tumors, which have a wide variety of primary tumor localizations, morphologic types, functional activities, and clinical presentations...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0016-5
更新日期:2001-06-01 00:00:00
abstract::Evaluation of prognostic factors of adenocarcinoma of Vater's ampulla is still a matter of debate. The aim of this study was to evaluate retrospectively factors that influence early and long-term outcomes in a 20-year single-institution experience on ampullary carcinoma. A total of 94 consecutive patients with ampulla...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7498-x
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:Treatment of peripherally located liver tumors with diaphragmatic invasion is technically demanding but does not preclude resection for cure. The aim of the present study was to compare patients undergoing combined liver and diaphragmatic resection with those submitted to hepatectomy alone so as to evaluate ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2083-9
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:With the progressive use of new diagnostic techniques, the management of penetrating abdominal stab wounds is changing. Most studies have been conducted in well-equipped trauma centers in developed countries, and there is a paucity of reports from general teaching hospitals with limited resources. We reviewe...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-1931-y
更新日期:2013-05-01 00:00:00
abstract:BACKGROUND:Laparoscopic proximal gastrectomy (LPG) is performed as a function-preserving surgery for patients with early proximal gastric malignant tumors; however, whether LPG has advantages postoperatively compared with laparoscopic total gastrectomy (LTG) is debatable, especially with regard to nutritional outcomes....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4625-7
更新日期:2018-10-01 00:00:00
abstract:PURPOSE:Advanced Trauma Life Support (ATLS®) is one of the world's best-known training programs for medical providers. Revisions of the ATLS manual have been evidence based for a number of years. In 2011, a level 3 (S3) evidence- and consensus-based guideline on the treatment of patients with severe and multiple injuri...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3063-z
更新日期:2015-08-01 00:00:00
abstract::Open gastric surgery in elderly patients is associated with higher morbidity and mortality rates than those reported among younger individuals. Therefore, minimally invasive surgery may have a larger impact on the elderly compared to the younger age group. The objective of this study was to evaluate the experience of ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0208-5
更新日期:2005-12-01 00:00:00
abstract::This study described the various components of access to care for resectable colorectal cancer, and correlated the timeliness of these components with patient satisfaction. With a prospective/retrospective cohort design, all patients undergoing surgical resection for primary colorectal cancer from 2/1/01 to 15/12/01, ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7955-1
更新日期:2005-11-01 00:00:00
abstract:BACKGROUND:Liver transplantation for biliary atresia is indicated whenever a Kasai portoenterostomy is considered unfeasible. However, the timing of liver transplantation in biliary atresia has not been precisely defined. Excessive shortening of hepatocellular telomeres may occur in patients with biliary atresia, and t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1453-z
更新日期:2012-04-01 00:00:00
abstract::There is debate regarding use of the stereotactic core-needle biopsy (SCNB) for highly suspicious mammographic lesions. This study compares a serial group of mammography-detected breast cancer patients treated before and after the use of SCNB. We studied 113 consecutive nonpalpable breast cancers between 1994 and 1996...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900510
更新日期:1998-10-01 00:00:00
abstract::Mesosigmoidoplasty is a nonresective procedure for nongangrenous sigmoid volvulus. It aims to correct the main pathogenetic factor of this condition, the narrow but long mesosigmoid. Although it had been demonstrated by intraoperative measurements that this has indeed achieved its purpose, recurrent volvulus has been ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7010-z
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:A small remnant liver volume is an important risk factor for posthepatectomy liver failure and can be predicted accurately by computed tomography (CT) volumetry using radiologic image analysis software. Unfortunately, this software is expensive and usually requires support by a radiologist. ImageJ is a freel...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9197-x
更新日期:2007-11-01 00:00:00
abstract::Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6264-1
更新日期:2002-09-01 00:00:00
abstract::Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group o...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010274
更新日期:2000-12-01 00:00:00
abstract:INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-015-3386-9
更新日期:2016-05-01 00:00:00
abstract:BACKGROUND:Owing to an aging society, both the number of operations for patients aged >85 years and the average age of patients admitted to the intensive care unit (ICU) are rapidly increasing. However, mortality is not an appropriate outcome measurement in patients aged >85 years; a more important outcome is home retu...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3830-5
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:In patients with negative sentinel lymph node biopsy (SLNB), axillary dissection (AD) can be avoided to reduce morbidities. However, there is only limited data on the rate of positive non-SLN (NSLN) in those who have micrometastasis and isolated tumor cells (ITC) in the literature. METHODS:We did a retrospe...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-2984-x
更新日期:2015-06-01 00:00:00
abstract::Among 26 patients with gallbladder carcinoma, 11 resected cases were studied retrospectively with respect to the preoperative imaging techniques and the operative procedures employed. Ultrasonography, endoscopic ultrasonography, and computed tomography were valuable in detecting gallbladder carcinoma preoperatively wh...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658723
更新日期:1991-05-01 00:00:00
abstract:BACKGROUND:A substantial number of people are suffering from gastroesophageal reflux disease (GERD). The indication for surgical treatment is the failure of medical treatment in patients with objectively verified GERD. The use of PPIs has been noted to increase with the length of follow-up after fundoplication, raising...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3924-8
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Geriatric collaborative care models improve postoperative outcomes for older adults. However, there are limited data exploring how preoperative geriatric assessment may affect surgical cancellations. METHODS:This is a single-center retrospective cohort analysis. Patients enrolled in the Perioperative Optimi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05772-z
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:The prognosis of advanced hepatocellular carcinoma (HCC) remains poor, particularly in patients with tumor thrombi (TT) in the major vessels. PATIENTS AND METHODS:From July 1992 to October 2004, 161 patients diagnosed as having advanced HCC with major vascular involvement were seen consecutively at our hosp...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0250-3
更新日期:2006-03-01 00:00:00
abstract:INTRODUCTION:Parastomal hernia (PH) is a frequent complication after end-colostomy formation. PH may negatively influence the quality of life in end-colostomy patients. Our study investigates the quality of life and body image (BI) in patients with an end-colostomy. METHODS:We conducted a cross-sectional study of end-...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3107-4
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:The incidence, pattern, and severity of sleep disturbance and cognitive dysfunction has not been well characterized for patients with primary hyperparathyroidism (PHPT). There is no agreement on the mechanism of the development or resolution of such symptoms, and in no previous study has cerebral activity be...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0361-x
更新日期:2006-05-01 00:00:00
abstract:BACKGROUND AND OBJECTIVES:We determined the rates of initial lymph node metastasis following curative resection of mass-forming type-intrahepatic cholangiocarcinoma (ICC) in patients with and without hepatitis virus infection. METHODS:We enrolled 87 patients between January 2000 and December 2013 with ICC without preo...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3843-0
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Neuroendocrine neoplasia (NEN) with unknown primary site (NEN-CUP tumors) may have a poor prognosis. We evaluated the clinical presentation, therapy, outcome, and risk factors for adverse outcomes in patients who had these tumors. METHODS:In 243 patients who had NEN, a retrospective review was performed in ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-2963-2
更新日期:2015-06-01 00:00:00
abstract::To characterize hepatocellular carcinoma (HCC) cells with mutant (m) p53 protein histologically, we examined 68 main nodules and 20 accessory lesions of 72 patients with HCC who underwent hepatic resection between October 1990 and September 1993. Some sections were fixed in periodate-lysine-paraformaldehyde, embedded ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900033
更新日期:1996-02-01 00:00:00
abstract::A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid disease of the liver by means of this alternative surgical technique....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6558-3
更新日期:2003-02-01 00:00:00