Treatment of hepatic metastases from gastroenteropancreatic neuroendocrine tumors: role of liver transplantation.

Abstract:

:The role of liver transplantation in malignancy has been discussed, but controversially, over the past two decades. This is particularly true for hepatic metastases from neuroendocrine tumors, which have a wide variety of primary tumor localizations, morphologic types, functional activities, and clinical presentations. Despite generally slow tumor progression, the prognosis is often unpredictable. Total hepatectomy and liver replacement has been offered primarily to patients with nonresectable metastases and symptomatic disease. The results from retrospective single and multicentric analyses show that most liver recipients experience significant palliation despite tumor recurrence, and in some patients long-term cure can be achieved. The existing data emphasize the importance of proper selection and timing for this approach.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Ringe B,Lorf T,Döpkens K,Canelo R

doi

10.1007/s00268-001-0016-5

keywords:

subject

Has Abstract

pub_date

2001-06-01 00:00:00

pages

697-9

issue

6

eissn

0364-2313

issn

1432-2323

journal_volume

25

pub_type

杂志文章
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