Abstract:
BACKGROUND:Intraoperative identification of the difficult-to-spot parathyroid gland is critical during surgery for thyroid and parathyroid disease. Recently, intrinsic fluorescence of the parathyroid gland was identified, and a new method was developed for intraoperative detection of the parathyroid with an original fluorescent detection apparatus. Here, we describe a method for intraoperative detection of the parathyroid using a ready-made photodynamic eye (PDE) system without any fluorescent dye or contrast agents. METHODS:Seventeen patients who underwent surgical treatment for thyroid or parathyroid disease at Kagoshima University Hospital were enrolled in this study. Intrinsic fluorescence of various tissues was detected with the PDE system. Intraoperative in vivo and ex vivo intrinsic fluorescence of the parathyroid, thyroid, lymph nodes and fat tissues was measured and analyzed. RESULTS:The parathyroid gland had a significantly higher fluorescence intensity than the other tissues, including the thyroid glands, lymph nodes and fat tissues, and we could identify them during surgery using the fluorescence-guided method. Our method could be applicable for two intraoperative clinical procedures: ex vivo tissue identification of parathyroid tissue and in vivo identification of the location of the parathyroid gland, including ectopic glands. CONCLUSION:The PDE system may be an easy and highly feasible method to identify the parathyroid gland during surgery.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Shinden Y,Nakajo A,Arima H,Tanoue K,Hirata M,Kijima Y,Maemura K,Natsugoe Sdoi
10.1007/s00268-017-3903-0subject
Has Abstractpub_date
2017-06-01 00:00:00pages
1506-1512issue
6eissn
0364-2313issn
1432-2323pii
10.1007/s00268-017-3903-0journal_volume
41pub_type
杂志文章abstract:BACKGROUND:The open surgical wound is exposed to cold dry ambient air, resulting in substantial heat loss through radiation, evaporation, and convection. At the same time, anesthesia decreases the patient's core temperature. Despite preventive measures, mild intraoperative hypothermia has been associated with postopera...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-012-1735-5
更新日期:2012-11-01 00:00:00
abstract::The phrase "outcomes studies" is usually used to describe those studies where outcome is assessed in large cohorts of patients, often using data from administrative databases. They are used to determine the role and impact of variations in the structure and process of health care delivery play in routine practice. Opt...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
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abstract::In 1989-90, all 37 lung cancer patients scheduled for surgery underwent transesophageal endoscopic ultrasonography (EUS) for pre-operative detection of hilar and mediastinal lymph node metastases. An electronic ultrasonic fiberscope with a linear array (EPB-503-FS, Machida-Toshiba) was used. Of 380 nodes surgically re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067013
更新日期:1992-09-01 00:00:00
abstract::Transjugular intrahepatic portosystemic shunt (TIPS) is being increasingly utilized prior to liver transplantation for portal hypertensive bleeding refractory to sclerotherapy or as initial management of variceal bleeding. The impact of TIPS on subsequent orthotopic liver transplantation (OLT) is uncertain. The purpos...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/BF00299089
更新日期:1994-11-01 00:00:00
abstract::This study was first designed to investigate systematically the kinetics of surface expression of scavenger receptors (SRs) and CD14 on alveolar macrophages in vivo and in vitro and their relation with local pro- and antiinflammatory responses in endotoxemia. The expression of SR and CD14 in lungs was down- and up-reg...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6548-5
更新日期:2003-01-01 00:00:00
abstract::Over the past three decades Canada has developed an exemplary system of universal health care. However, current financial constraints threaten to undermine the very foundation of the system that represents Canada's respect for social justice. The first of these two articles (Part 1) discusses the unique characteristic...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00298897
更新日期:1994-09-01 00:00:00
abstract:BACKGROUND:The impact of postoperative complications (POCs) on long-term survival outcomes following hepatic resection for colorectal liver metastasis (CRLM) is in controversy. The aim of the present meta-analysis was to systematically evaluate the POC effect on overall survival (OS) and disease-free survival (DFS) in ...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-015-3019-3
更新日期:2015-07-01 00:00:00
abstract:BACKGROUND:It has been reported that the paraesophagogastric devascularization with esophageal transection procedure, also known as the modified Sugiura procedure, was effective in the treatment of variceal bleeding. However, it was not widely accepted by other surgeons because of the high rate of rebleeding, complicat...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2478-2
更新日期:2014-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0055-4
更新日期:2005-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-7778-0
更新日期:2006-04-01 00:00:00
abstract::The introduction of laparoscopic techniques for the management of biliary stone disease has expanded the therapeutic choices for surgeons confronted with choledocholithiasis. As new strategies emerge, the treatment of cholelithiasis and choledocholithiasis remains controversial. This paper discusses the options availa...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900531
更新日期:1998-11-01 00:00:00
abstract:BACKGROUND:Teamwork is fundamental to effective surgery, yet there are currently no measures of teamwork to guide training, evaluate team interventions or assess the impact of teamwork on outcomes. We report the first steps in the development of an observational assessment of teamwork and preliminary findings. METHOD:...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0488-9
更新日期:2006-10-01 00:00:00
abstract::Reported incidence rates of carcinoma in patients with achalasia and the prevalence of achalasia in patients with esophageal cancer vary widely in the literature. The prognosis of an "achalasia-carcinoma" is generally considered poor, although systematic studies assessing the incidence, prevalence, and prognosis of pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0026-3
更新日期:2001-06-01 00:00:00
abstract:INTRODUCTION:Preventing secondary insult to the brain is imperative following traumatic brain injury (TBI). Although TBI does not preclude nonoperative management (NOM) of splenic injuries, development of hypotension in this setting may be detrimental and could therefore lead trauma surgeons to a lower threshold for op...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4494-0
更新日期:2018-08-01 00:00:00
abstract:BACKGROUND:Strong evidence has confirmed the benefit of laparoscopy in colorectal cancer resection but remains a challenging procedure. It is not clear that such promising results in selected patients translate into a favorable risk-benefit balance in real practice. We conducted a multicenter national observational reg...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-015-3050-4
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Ultrasound (US) and sestamibi (MIBI) are traditionally considered positive or negative. The purpose of this study was to define and test a new scoring system for MIBI and US and to determine whether this can improve their accuracy for primary hyperparathyroidism. METHODS:This is a prospective study of 200 c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1666-1
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:Closure of loop ileostomy can be safely performed using sutures or staplers. The aim of the present study was to compare the cost effectiveness of three different techniques. METHODS:A total of 128 consecutive patients who underwent closure of loop ileostomy between January 2002 and December 2008 were analy...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-010-0787-7
更新日期:2010-12-01 00:00:00
abstract::Expression of sialyl-Lewisx (sLex) antigen was studied immunohistochemically in 110 resected human gastric carcinomas using an anti-sLex monoclonal antibody. Lymph node, liver, and peritoneal metastases were clearly more prevalent in tumors expressing high levels of sLex than in those with no or low-level sLex express...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900304
更新日期:1997-09-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-7903-0
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:Nipple-sparing mastectomy (NSM) has gained widespread popularity in recent years. Nonetheless, patient selection, technical consideration and oncological safety of its extension to breast cancer treatment remain uncertain. Few publications have reviewed the application of NSM in Asian populations. METHODS:W...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4197-y
更新日期:2018-05-01 00:00:00
abstract::Idiopathic portal hypertension (IPH) requires invasive measures to prevent rupture and bleeding of esophagogastric varices. However, the long-term results of shunt surgery for IPH have not been reported. In particular, the pros and cons of surgery that preserves the spleen and its long-term hematologic effects have no...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7656-9
更新日期:2005-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680010167
更新日期:2000-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-009-0022-6
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:Medullary thyroid cancer (MTC) represents the third most common type of thyroid cancer, and the prognosis depends on the stage of the disease at diagnosis and completeness of tumor resection. In 2009, the American Thyroid Association (ATA) published guidelines with evidence-based recommendations for the trea...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3643-6
更新日期:2016-12-01 00:00:00
abstract::Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6264-1
更新日期:2002-09-01 00:00:00
abstract:BACKGROUND:Thymic epithelial tumors are characterized by slow growth and variable malignant behavior. We present our experience on the surgical management of these tumors. MATERIALS AND METHODS:We conducted a retrospective analysis of patients with thymomas undergoing modified maximal thymectomy over a period of 16 ye...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0097-0
更新日期:2009-08-01 00:00:00
abstract:BACKGROUND:Burns are a major public health concern, affecting mostly low- and middle-income countries. However, there is a lack of epidemiological studies on burns in these countries, particularly in Latin American countries. Our aim was to analyze nationwide demographic, epidemiological and economic characteristics of...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3988-5
更新日期:2017-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:2020-04-01 00:00:00
abstract:BACKGROUND:Laparoscopic cholecystectomy is first-line treatment for uncomplicated gallstone disease in high-income countries due to benefits such as shorter hospital stays, reduced morbidity, more rapid return to work, and lower mortality as well-being considered cost-effective. However, there persists a lack of uptake...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3851-0
更新日期:2017-05-01 00:00:00
abstract::This study was conducted retrospectively to examine the efficacy of Traverso reconstruction compared with Billroth I reconstruction after pylorus-preserving pancreaticoduodenectomy, in the prevention of several complications. Pylorus-preserving pancreaticoduodenectomy is an aggressive surgery, and insufficiency of the...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7697-0
更新日期:2005-07-01 00:00:00