Abstract：
:Expression of sialyl-Lewisx (sLex) antigen was studied immunohistochemically in 110 resected human gastric carcinomas using an anti-sLex monoclonal antibody. Lymph node, liver, and peritoneal metastases were clearly more prevalent in tumors expressing high levels of sLex than in those with no or low-level sLex expression. No correlation was found between sLex expression and histologic grade or histologic type of the Lauren classification. Among the tumors with lymph node metastasis, 44% expressed high levels of sLex in both the primary tumor and involved lymph nodes, and 14% of the metastatic lesions demonstrated increased sLex expression. The 5-year survival rate of the patients undergoing complete (R0) gastric resections was 60% in the sLex high-expression group, which was significantly lower than that of the sLex low-expression group (81%) and of the no-expression group (87%) (p < 0.05). These results suggest that high-level sLex expression is related to both an increased risk of metastasis and poor prognosis in gastric cancer patients.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Ura H,Denno R,Hirata K,Yamaguchi K,Yasoshima T,Shishido Tdoi
10.1007/s002689900304subject
Has Abstractpub_date
1997-09-01 00:00:00pages
773-6issue
7eissn
0364-2313issn
1432-2323journal_volume
21pub_type
临床试验,杂志文章abstract：BACKGROUND:Anal manometry is a useful tool for testing the effectiveness of surgical treatment. However, most techniques for anal pressure measurement are not easily available because of high cost. The aim of the present study was to introduce an easy and reproducible method for measuring anal pressures in testing the ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0365-1
更新日期：2007-02-01 00:00:00
abstract：BACKGROUND:Esophagectomy carries high morbidity, mainly respiratory. Minimally invasive surgery has been demonstrated to improve postoperative outcome in digestive surgery, without impairment of oncological results. A prospective study was conducted to evaluate feasibility, postoperative outcome, and mid-term oncologic...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0627-3
更新日期：2006-08-01 00:00:00
abstract：:The moral dilemmas faced by surgeons worldwide who treat patients infected with the human immunodeficiency virus (HIV) can be viewed against the background of experience in sub-Saharan countries, where the community prevalence is in excess of 25% (90% of hospital inpatients). When seeking consent for an HIV test befor...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7101-x
更新日期：2003-08-01 00:00:00
abstract：:The purpose of this study was to evaluate the surgical outcome of completion thyroidectomy in patients with presumed unilateral well-differentiated thyroid cancer (WDTC). The medical records of all patients having had unilateral thyroid lobectomy for WDTC, who subsequently underwent completion thyroidectomy, were revi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067365
更新日期：1992-07-01 00:00:00
abstract：:Surgical exposure of the recurrent laryngeal nerve decreases the incidence of nerve injuries during thyroid surgery. Intraoperative neuromonitoring was introduced to facilitate identification and protection of the recurrent laryngeal nerve. Between February 1996 and June 2002 a total of 288 patients underwent thyroid ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7226-6
更新日期：2004-06-01 00:00:00
abstract：:Factors responsible for recurrence of esophageal cancer were investigated in 90 patients who underwent extended radical esophagectomy with three-field dissection for a squamous cell carcinoma in the thoracic esophagus. The initial tumor recurrence was grouped as either locoregional (site of the primary tumor, anastomo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900228
更新日期：1997-03-01 00:00:00
abstract：BACKGROUND:This study aimed to evaluate the recurrence rates, timings, locations, and risk factors, and survival in patients with lymph node-negative superficial esophageal squamous cell carcinomas (ESCCs). METHODS:We investigated 167 patients with pathological T1 thoracic ESCC who underwent curative esophagectomy wit...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3454-9
更新日期：2016-07-01 00:00:00
abstract：INTRODUCTION:Although seemingly straightforward, tube thoracostomy (TT) has been associated with complication rates as high as 30 %. A lack of a standardized nomenclature for reporting TT complications makes comparison and evaluation of reports impossible. We aim to develop a classification method in order to standardi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-015-3158-6
更新日期：2015-11-01 00:00:00
abstract：:Eighty patients undergoing cholecystectomy were either assigned deliberately (n = 30) or randomized (n = 50) to drainage (n = 38) or nondrainage (n = 42). Subhepatic collections were seen on ultrasonography (US) after 48 to 72 hours in 12 of 35 patients with drainage and 24 of 42 patients without drainage (p < 0.05). ...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/BF01655718
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:Classification of the open abdomen (OA) status is essential for clinical studies on the subject and may help to improve OA therapy. This is a validity and reliability analysis of the OA classification proposed by the World Society of the Abdominal Compartment Syndrome in 2013. METHODS:Prospective data on 11...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2716-7
更新日期：2014-12-01 00:00:00
abstract：:Cost-benefit and cost-effectiveness analyses (CEAs) are only now beginning to be used by business, government, and policymakers to evaluate various medical treatments. The evolution of why CEAs are being demanded is reviewed. To date, a formal CEA of obesity treatments has not been published. This article outlines how...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900508
更新日期：1998-09-01 00:00:00
abstract：OBJECTIVES:Postoperative pancreatic fistula (POPF) is a major complication and main cause of mortality after pancreaticoduodenectomy (PD). Afferent loop decompression technique (ALDT) has theoretical feasibility to reduce the rate of POPF. The aim of this study is to determine whether ALDT is a protective factor for PO...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4679-6
更新日期：2018-11-01 00:00:00
abstract：BACKGROUND:Linitis plastica-type gastric carcinoma remains a disease with poor prognosis despite an aggressive surgical approach. Although a prominent pattern of disease failure is peritoneal carcinomatosis, some patients experience rapid disease progression without signs of the peritoneal disease. METHODS:Clinicopath...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9672-z
更新日期：2008-09-01 00:00:00
abstract：OBJECTIVE:The prognosis of Fournier's gangrene (FG) depends on early diagnosis and management. In this study, our objective was to identify the distinct features of FG that may influence the clinical outcome. METHODS:A retrospective chart review was performed in patients with a diagnosis of FG between January 1999 and...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0777-3
更新日期：2006-09-01 00:00:00
abstract：:This paper describes a model humanitarian mission to Guyana; it illustrates the value of excellent ongoing care in collaboration with local physicians and surgeons, cooperation with local government and medical officials, and frequent periodic follow-up missions (always to the same hospital, working with the same staf...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3049-x
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:In 2002, the UICC/AJCC TNM classification for papillary thyroid carcinoma was revised. In this study, we examined the validity of this classification system by investigating the predictors of disease-free survival (DFS) and cause-specific survival (CSS) in patients. METHODS:We examined various clinicopathol...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-006-0455-0
更新日期：2007-04-01 00:00:00
abstract：INTRODUCTION:Urogenital dysfunction is a well recognized complication of rectal cancer surgery. The aim of this study was to assess the impact of autonomic nerve preservation (ANP) and lateral node dissection (LND) on male urogenital function after total mesorectal excision for lower rectal cancer. METHODS:We studied,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0050-9
更新日期：2006-06-01 00:00:00
abstract：BACKGROUND:Hepatic resection for hepatocellular carcinoma (HCC) patients with liver cirrhosis and severe hypersplenic thrombocytopenia is risky and controversial. METHODS:From 1989 to 2005, 341 patients underwent hepatic resection for HCC in our hospital. Of these, 15 patients were concomitant with severe thrombocytop...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9442-3
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:The objective of this study was to determine whether rat insulin promoter (RIP) could, in a mouse model, direct expression of an adenovirus-mediated reporter gene specifically into pancreatic islets via systemic delivery. METHODS:Five hundred and eight base pairs of the RIP DNA sequence were constructed int...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0688-3
更新日期：2006-08-01 00:00:00
abstract：:Noninvasive diagnosis of cavernous hemangioma of the liver is an important step in the investigation of patients with focal hepatic lesions since biopsy may result in life-threatening hemorrhage. To determine the diagnostic accuracy of 99m-technetium red blood cell (99mTc-RBC) imaging with tomography, 50 patients with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658668
更新日期：1990-07-01 00:00:00
abstract：INTRODUCTION:Difficulties with liver transplantation (LT)-related surgical techniques are great challenges for young surgeons. Thus, young surgeons need to undergo systematic preclinical training. However, an optimal training system for LT is still lacking. This study aims to evaluate the safety and educational value o...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05300-8
更新日期：2020-04-01 00:00:00
abstract：:Although HLA matching can improve organ graft survival, well matched grafts fail and poorly matched ones survive. Recently evidence has been found that perinatal exposure to noninherited antigens (NIMAs) has a lifelong impact on the immune repertoire of the individual. The state of the art of the influence of NIMAs on...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010132
更新日期：2000-07-01 00:00:00
abstract：BACKGROUND:Laparoscopic rectal resection (LRR) for cancer is a challenging procedure, with conversion to open surgery being reported in up to 30% of cases. Since only a few studies with short follow-up have compared converted LRR and open RR (ORR), it is unclear if conversion to open surgery should be prevented by pref...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4614-x
更新日期：2018-10-01 00:00:00
abstract：:We investigated the effect of radiofrequency ablation (RFA) of the liver on cell-mediated immunity in rats. Sprague-Dawley rats were divided into five groups: control group that did not have any procedure, a sham-operation group that underwent laparotomy, a lobectomy group that had left lateral lobectomy of the liver,...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-7728-x
更新日期：2005-06-01 00:00:00
abstract：BACKGROUND:The Emergency Hospital in Battambang, Cambodia, is essentially a surgical center for victims of injuries. METHODS:Using methods previously described, operating costs were calculated, and effectiveness of treatment was estimated for 957 patients undergoing 895 surgical procedures over a 3 month period (Octob...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9708-4
更新日期：2008-11-01 00:00:00
abstract：INTRODUCTION:Gastroesophageal reflux disease is common in Western societies, although the prevalence of reflux symptoms in the community is not well described. In this study we determined the prevalence of symptoms of gastroesophageal reflux and other "esophageal" symptoms, and the consumption of medication for reflux ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9780-9
更新日期：2009-01-01 00:00:00
abstract：BACKGROUND:There is no consensus opinion on a definitive surgical management option for ranulas to curtail recurrence, largely from the existing gap in knowledge on the pathophysiologic basis. AIM:To highlight the current scientific basis of ranula development that informed the preferred surgical approach. DESIGN:Ret...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-3901-2
更新日期：2017-06-01 00:00:00
abstract：:Lower esophageal sphincter pressure has been assessed pre-operatively, intra-operatively,and more than 6 months postoperatively in 34 patients having antireflux surgery for gastro-esophageal reflux disease. The sphincter pressures associated with the outcome in relation to pH measured reflux and the symptoms of recurr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02071543
更新日期：1992-03-01 00:00:00
abstract：BACKGROUND:Distal splenorenal shunt and coronary caval shunt are commonly used for selective decompression of esophagogastric varices, but they may not solve severe hypersplenism and their application may be hampered by the presence of splenic venous thrombosis or a left gastric vein (LGV) situated deeply behind the pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4796-2
更新日期：2019-02-01 00:00:00
abstract：BACKGROUND:Flow disruptions (FDs) are deviations from the progression of care that compromise safety or efficiency. The frequency and specific causes of FDs remain poorly documented in trauma care. We undertook this study to identify and quantify the rate of FDs during various phases of trauma care. METHODS:Seven trai...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2306-0
更新日期：2014-02-01 00:00:00
