Role of surgical treatment for recurrent hepatocellular carcinoma after hepatic resection.

Abstract:

:From 1978 to 1989, 164 patients underwent hepatic resection for hepatocellular carcinoma at our institution. The carcinoma was resected completely in 149 patients. Sixteen patients were excluded from this study because it was not known whether they were recurrent or disease free, or because death occurred as a result of surgical complications. Recurrent disease occurred in 48.1% of the remaining 133 patients. Fifty-seven patients had recurrent tumor only in the residual liver. A second hepatic resection was performed in 14 cases, 22 received intraarterial chemotherapy and/or arterial embolization without resection,a nd the remaining 21 received no anticancer therapy. The 5-year survival rate of patients who had a second resection was 92.0%. Recurrences in distant organs occurred in 14 patients, and the recurrent carcinoma was resected in five cases. Four of these 5 patients survived more than 3 years after the second surgery. Aggressive surgical resection of recurrent HCC, even for distant metastasis, is a viable approach, and may produce long-term survivors.

journal_name

World J Surg

journal_title

World journal of surgery

authors

Nakajima Y,Ohmura T,Kimura J,Shimamura T,Misawa K,Matsushita M,Sato N,Une Y,Uchino J

doi

10.1007/BF01659099

subject

Has Abstract

pub_date

1993-11-01 00:00:00

pages

792-5

issue

6

eissn

0364-2313

issn

1432-2323

journal_volume

17

pub_type

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