Abstract：
BACKGROUND:Patients with hepatocellular carcinoma (HCC) who underwent hepatectomy often developed an intrahepatic recurrence, even though it was a curative one. The relationship between surgery-induced liver damage and the recurrence of HCC has not been described. This study evaluated whether posthepatectomy liver failure, as defined by the International Study Group of Liver Surgery, affected the recurrence of HCC. METHODS:We performed a retrospective cohort study of 488 patients with HCC who underwent hepatectomy between 2004 and 2012 at Kyoto University Hospital. Early posthepatectomy liver failure (EPLF) was defined as liver failure occurring between postoperative days 5 and 10. The patients were divided into an EPLF group and a non-EPLF group. Disease-free survival (DFS) was compared between these groups. The influences of host-related, surgery-related, and tumor-related factors on patient outcomes were evaluated using multivariate analyses. RESULTS:The EPLF group and the non-EPLF group contained 153 and 335 patients, respectively. The probability of DFS was significantly increased in the non-EPLF group (median: 574 days) compared to the EPLF group (median: 348 days) (hazard ratio, HR [95 % confidence interval, CI] 1.61 [1.29-2.00]). The multivariate analysis revealed that EPLF was an independent factor for DFS (HR [95 % CI] 1.43 [1.13-1.81]), besides the factors previously described, including fibrosis (1.32 [1.05-1.67]), stage (1.85 [1.34-2.51]), tumor differentiation (1.46 [1.11-1.89]), and des-γ-carboxyprothrombin (1.39 [1.10-1.74]). CONCLUSIONS:EPLF was associated with postoperative HCC recurrence. The prevention of EPLF might improve the prognosis of patients with HCC.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Iguchi K,Hatano E,Yamanaka K,Tanaka S,Taura K,Uemoto Sdoi
10.1007/s00268-013-2247-7subject
Has Abstractpub_date
2014-01-01 00:00:00pages
150-8issue
1eissn
0364-2313issn
1432-2323journal_volume
38pub_type
杂志文章abstract：:Treacher Collins Syndrome is a rare bilateral congenital deformity occurring in 1 in 10,000 births. It is also known, in the European literature, as Franceschetti Syndrome, and is additionally known as mandibulofacial dysostosis. It is a syndrome with a very wide spectrum of manifestations characterized by distortions...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01660753
更新日期：1989-07-01 00:00:00
abstract：:Although palpable axillary lymphadenopathy is most often related to benign disorders, it may be a harbinger of an underlying advanced malignancy. Fewer than 1% of patients diagnosed with breast cancer initially present with axillary metastases as their only clinical manifestation. This study represents the Mayo Clinic...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7290-y
更新日期：2004-06-01 00:00:00
abstract：:With limited resources and the current concerns about using animals for research purposes, the needs must be clear when setting up trauma and sepsis experiments for pharmacologic interventions. Such interventions are performed typically for four reasons: (1) to study the pathophysiologic role of certain mediators (whi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900077
更新日期：1996-05-01 00:00:00
abstract：:There is debate regarding use of the stereotactic core-needle biopsy (SCNB) for highly suspicious mammographic lesions. This study compares a serial group of mammography-detected breast cancer patients treated before and after the use of SCNB. We studied 113 consecutive nonpalpable breast cancers between 1994 and 1996...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900510
更新日期：1998-10-01 00:00:00
abstract：:This paper describes a model humanitarian mission to Guyana; it illustrates the value of excellent ongoing care in collaboration with local physicians and surgeons, cooperation with local government and medical officials, and frequent periodic follow-up missions (always to the same hospital, working with the same staf...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3049-x
更新日期：2015-08-01 00:00:00
abstract：BACKGROUND:New medical therapies available to ulcerative colitis (UC) patients have influenced operative mortality for patients requiring colectomy. We sought to examine trends in treatment and outcome for UC patients treated surgically. METHODS:A review of 36,447 UC patients from the Nationwide Inpatient Sample was p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0910-9
更新日期：2011-03-01 00:00:00
abstract：:It is difficult to evaluate precisely the effects of one individual on an entire discipline such as surgery. Indeed, it is impossible to do so when such a discipline spans so vast a country as the United States of America. Nevertheless, as a mountain peak can be seen from afar, so may one perceive the influence of man...
journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1007/s002689900357
更新日期：1998-01-01 00:00:00
abstract：INTRODUCTION:The coexistence of an enterocutaneous fistula (ECF) with large abdominal wall defects represent one of the most demanding situations seen by a surgeon. Simultaneous treatment of ECF closure with abdominal wall defect closure has been widely debated. Our objective was to determine if the type of abdominal w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05635-7
更新日期：2020-10-01 00:00:00
abstract：BACKGROUND:Africa's health workforce crisis has recently been emphasized by major international organizations. As a part of this discussion, it has become apparent that the workforce required to deliver surgical services has been significantly neglected. METHODS:This paper reviews some of the reasons for this relative...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9473-4
更新日期：2008-06-01 00:00:00
abstract：BACKGROUND:The present study evaluated outcomes of patients undergoing proximal diversion using either a loop ileostomy or loop colostomy following distal colorectal resection for malignant and non-malignant disease. METHODS:A literature search of the Medline, Ovid, Embase and Cochrane databases was performed to ident...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-006-0218-y
更新日期：2007-05-01 00:00:00
abstract：BACKGROUND:Adrenocortical carcinoma (ACC) is a rare and aggressive malignancy with poor prognosis, as a majority of patients present with advanced disease. Current adjuvant strategies for metastatic patients include mitotane or other cytotoxic agents and carry a significant morbidity as well as a low (<10 %) 5-year sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2532-0
更新日期：2014-06-01 00:00:00
abstract：BACKGROUND:To evaluate whether the preoperative magnetic resonance angiography (MRA) can predict the risk of cerebral ischemia associated with the carotid endarterectomy (CEA). METHODS:Between January 2004 and December 2010, 382 consecutive patients (mean age: 56.6 years; range: 45-78 years) were identified to have un...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1851-2
更新日期：2013-03-01 00:00:00
abstract：:During the course of tumor progression the differentiated morphologic and functional characteristics of differentiated thyroid carcinomas (DTC) disappear. This corresponds to more aggressive growth, metastatic spread, and loss of iodine uptake. Experimental data give strong evidence that differentiated functions of io...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900436
更新日期：1998-06-01 00:00:00
abstract：:The surgical treatment of groin hernias continues to undergo technical modifications. The introduction of minimally invasive surgery had added a possible new dimension, replacing an inguinal approach by laparoscopy. Conceived some 15 years ago, the thesis was subjected to a clinical trial where coincidental abdominal ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01655704
更新日期：1993-01-01 00:00:00
abstract：BACKGROUND:The lung is the most common site of extrahepatic metastasis from hepatocellular carcinoma (HCC). The aim of this study was to evaluate the significance and long-term outcomes of pulmonary metastasectomy for HCC, especially in patients with multiple nodules or repeated pulmonary recurrence. METHODS:We retros...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3213-3
更新日期：2016-02-01 00:00:00
abstract：:Transcutaneous laryngeal ultrasonography (TLUSG) is a promising alternative to laryngoscopy in vocal cords (VCs) assessment which might be challenging in the beginning. However, it remains unclear when an assessor can provide proficient TLUSG enough to abandon direct laryngoscopy . Eight surgical residents (SRs) witho...
journal_title：World journal of surgery
pub_type： 历史文章,杂志文章
doi：10.1007/s00268-015-3348-2
更新日期：2016-03-01 00:00:00
abstract：:Nuss described a minimally invasive technique for correcting pectus excavatum in children. A curved stainless-steel bar is inserted behind the sternum through the chest cavity with the convex surface face down, then rotated 180 degrees to elevate the sternum and correct the deformity. The procedure gained wide accepta...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6519-x
更新日期：2002-10-01 00:00:00
abstract：INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-015-3386-9
更新日期：2016-05-01 00:00:00
abstract：:Although peptic gastroduodenal ulcers are rarely treated surgically today, when surgery is required a laparoscopic approach is possible with its well known advantages. The most widely used technique is vagotomy by various modalities. Training in laparoscopy requires good instrumentation to avoid complications. Vagotom...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689910044
更新日期：2000-03-01 00:00:00
abstract：BACKGROUND:There is a paucity of data on the presentation and surgical management of pheochromocytoma in developing nations, particularly in Africa. METHODS:This study was a retrospective review, which included all patients managed by the Groote Schuur Hospital/University of Cape Town Endocrine Surgery unit for pheoch...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05420-6
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:In the past decade, Enhanced Recovery after Surgery (ERAS) protocols have been implemented in several fields of surgery. With these protocols, a faster recovery and shorter hospital stay can be accomplished without an increase in morbidity or mortality. The purpose of this study was to review systematically ...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-013-2044-3
更新日期：2013-08-01 00:00:00
abstract：INTRODUCTION:The quantification and analysis of adverse events is essential to benchmark surgical outcomes and establish a foundation for quality improvement interventions. We developed a hybrid electronic medical record (HEMR) system for the accurate collection and integration of data into a structured morbidity and m...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2766-x
更新日期：2015-01-01 00:00:00
abstract：:Octenidine HCl is new topical antiseptic solution for wounds and abdominal washing that has been found to be highly effective for inactivating scolices in an in vitro study. However, the effects of octenidine HCl on the liver are not yet known. The aim of this study was to determine if there are any histopathologic ch...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9022-6
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:The Acute Care Surgery (ACS) model was developed as a dedicated service for the provision of 24/7 nontrauma emergency surgical care. This systematic review investigated which components are essential in an ACS model and the state of implementation of ACS models worldwide. METHODS:A literature search was con...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-020-05536-9
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Only few studies have compared laparoscopic total mesorectal excision (LTME) and open total mesorectal excision (OTME) for rectal cancer with follow-up longer than 5 years. The aim of this study was to compare 10-year oncologic outcomes after LTME and OTME for nonmetastatic rectal cancer. METHODS:We conduct...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3631-x
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Segmentectomy for radiologically pure solid tumors is still controversial because these tumors are more aggressive in malignancy than those with ground-glass opacity. This study aimed to determine the feasibility of intentional segmentectomy for pure solid small-sized lung cancer. METHODS:We retrospectively...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4514-0
更新日期：2018-08-01 00:00:00
abstract：:During the period 1979 to 1989, 0.1% of all cases of acute appendicitis at our institution occurred soon after another operative procedure. The interval between primary operation and appendectomy was 5 to 31 days (mean, 14 days). Signs and symptoms did not differ from those of classical acute appendicitis. Duration of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01675654
更新日期：1991-07-01 00:00:00
abstract：BACKGROUND:It has been reported that the paraesophagogastric devascularization with esophageal transection procedure, also known as the modified Sugiura procedure, was effective in the treatment of variceal bleeding. However, it was not widely accepted by other surgeons because of the high rate of rebleeding, complicat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2478-2
更新日期：2014-08-01 00:00:00
abstract：OBJECTIVE:Mirizzi syndrome (MS) is an uncommon presentation of cholelithiasis. This study aims to find the incidence and analyze the outcome of management of this condition at Riyadh Medical Complex (RMC) with particular reference to diagnostic methods and outcome of surgical treatment. METHODS:Retrospective study on ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0100-3
更新日期：2005-12-01 00:00:00
abstract：:The objective of this study was to assess the validity and responsiveness of a new quality of life instrument, the Patient Generated Index (PGI), in patients with rectal cancer. Thirty-three patients with rectal cancer were administered the PGI, the European Organisation for Research and Treatment of Cancer (EORTC) Qu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6360-2
更新日期：2002-11-01 00:00:00
