Abstract：
:Octenidine HCl is new topical antiseptic solution for wounds and abdominal washing that has been found to be highly effective for inactivating scolices in an in vitro study. However, the effects of octenidine HCl on the liver are not yet known. The aim of this study was to determine if there are any histopathologic changes after injecting octenidine HCl into the liver. A group of 50 male Sprague-Dawley rats were included in the study and randomly divided into five groups of 10 rats each, as follows: sham group; 0.09% NaCl group; 20% NaCl group; undiluted octenidine HCl group; 1% octenidine HCl group. The scolicidal agents (0.3 ml) were directly injected into the left lobe of the liver (except in the sham group). At 3 and 7 days after the injection, the rats were sacrificed, and the left lobe of the liver was harvested. Liver tissue was scored for degree of necrosis and the diameter of the necrosis examined under light microscopy. The highest scores were found in the undiluted octenidine HCl group, although a similar effect was observed in the 20% NaCl group. There was no necrosis in the sham group, the 0.09% NaCl group, or the 1% octenidine HCl group. All of the injury was coagulation-type necrosis. No mortality was observed throughout the study. The 1% octenidine HCl solution could thus be used as a scolicidal agent in liver tissue, whereas the undiluted form of octenidine and 20% NaCl solutions were shown to cause necrosis when directly injected into liver tissue in our animal model.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Arikan Y,Akbulut G,Sahin DA,Dilek FH,Saykol V,Dilek ONdoi
10.1007/s00268-007-9022-6subject
Has Abstractpub_date
2007-06-01 00:00:00pages
1280-3issue
6eissn
0364-2313issn
1432-2323journal_volume
31pub_type
杂志文章abstract：BACKGROUND:Idiopathic granulomatous mastitis (IGM) is a rare, benign, and chronic disease of the breast. Despite the various treatment approaches described for this disease, a gold standard treatment modality has not yet been defined. In this study, the effect of topical steroids was reviewed and assessed in patients w...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3147-9
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Billions of people worldwide lack access to safe affordable surgery. Surgical missions and non-governmental organisations (NGO) are vital in meeting this need, but long-term outcomes are rarely reported. Mercy Ships is a surgical NGO, and we aimed to measure disability-free survival, impact and patient satis...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3745-1
更新日期：2017-02-01 00:00:00
abstract：BACKGROUND:We reported phonatory recovery in the majority of 88 patients after recurrent laryngeal nerve (RLN) reconstruction. Here we analyzed factors that might influence the recovery, in a larger patient series. METHODS:At Kuma Hospital, 449 patients (354 females and 95 males) underwent RLN reconstruction with dire...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3634-7
更新日期：2016-12-01 00:00:00
abstract：:Endoscopic sphincterotomy (EST) is an established method for treatment of retained or recurrent common bile duct (CBD) calculi after cholecystectomy. Present experience shows that few patients have recurrent biliary tract complications, but follow-up periods are most often short. EST was performed in 147 patients with...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900043
更新日期：1996-03-01 00:00:00
abstract：BACKGROUND:The role of circular staplers in gastroduodenostomy during subtotal gastrectomy for gastric cancer has not been defined clearly. METHODS:A randomized clinical trial included patients with gastric cancer who underwent subtotal gastrectomy with either stapled (99 patients) or handsewn gastroduodenostomy (98 p...
journal_title：World journal of surgery
pub_type： 杂志文章,随机对照试验
doi：10.1007/s00268-011-1038-2
更新日期：2011-05-01 00:00:00
abstract：:Whether for hepatic trauma or transplantation, a surgeon's knowledge of hepatic anatomy commonly determines a patient's outcome. The first medically relevant anatomic studies of the liver emerged with the endeavors of Herophilus and Erasistratus between 310 and 280 bc. Yet it was not until after the development of ane...
journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1007/s002689900238
更新日期：1997-03-01 00:00:00
abstract：:A review of the literature describing the management of hepatic and splenic injuries indicates that as many as 67% of exploratory celiotomies for blunt trauma are reported as nontherapeutic. Avoiding unnecessary surgery through nonoperative management offers an attractive alternative. Nonetheless, nonoperative managem...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-001-0138-9
更新日期：2001-11-01 00:00:00
abstract：BACKGROUND:Diverticulitis is commonly diagnosed using ultrasound (US), followed by computed tomography (CT). Our aim was to determine the diagnostic accuracy of US compared with CT for patients with uncomplicated and complicated diverticulitis. METHODS:We reviewed medical records of 232 patients admitted with divertic...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2423-9
更新日期：2014-07-01 00:00:00
abstract：BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3060-2
更新日期：2015-08-01 00:00:00
abstract：:Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900319
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:Awake tracheostomy (AT) is aimed at securing the airway of patients with upper airway obstruction when other means are not feasible or have failed. Reports on AT in the literature are scarce. The goal of this study was to review our experience with the indications, complications and outcome of AT. METHODS:A...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4578-x
更新日期：2018-09-01 00:00:00
abstract：BACKGROUND:Recurrent laryngeal nerve palsy (RLNP) is one of the most common complications after thyroidectomy. We aim to evaluate the role of intraoperative corticosteroids in preventing or treating postoperative RLNP. MATERIALS AND METHODS:We conducted a prospective study of 295 patients who underwent either total lo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0399-9
更新日期：2006-03-01 00:00:00
abstract：:The pylorus-preserving pancreaticoduodenectomy (PPPD) is an alternative to the standard Whipple resection in the treatment of chronic pancreatitis. The operation is safe and can be performed with a low mortality rate. The most common early complication is delayed gastric emptying, which occurs in 25% to 30% of patient...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-003-7240-0
更新日期：2003-11-01 00:00:00
abstract：:Despite careful selection of cirrhotic patients with hepatocellular carcinoma (HCC), liver resection remains associated with a greater risk than in patients without underlying liver disease. In this study we assessed by multivariate analysis parameters associated with in-hospital mortality and morbidity in a selected ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00012259
更新日期：1997-05-01 00:00:00
abstract：:Telomerase adds hexameric repeats of 5'-TTAGGG-3' to the ends of chromosomal DNA (telomere) and has been implicated in cell immortalization and cellular senescence. The aim of this study was to measure quantitatively the telomerase activity and human telomerase RNA component (hTR) content in gastric cancer and to exam...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680010246
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:Abdominal packing (AP) in damage-control laparotomy (DCL) is a lifesaving technique that controls coagulopathic hemorrhage in severely injured trauma patients. However, the impact of the duration of AP on the incidence of re-bleeding and on intra-abdominal infections in penetrating abdominal trauma is not cl...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1745-3
更新日期：2012-12-01 00:00:00
abstract：BACKGROUND:Every day thousands of surgeons and patients negotiate their way through the complex process of decision-making about operative treatments. We conducted a series of qualitative studies, asking patients and surgeons to describe their experience and beliefs about informed decision-making and consent. This stud...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0021-7
更新日期：2009-07-01 00:00:00
abstract：BACKGROUND:Primary hyperparathyroidism (HPT) is often caused by a benign parathyroid tumor, adenoma; less commonly by multiglandular parathyroid disease/hyperplasia; and rarely by parathyroid carcinoma. Patients with multiple tumors require wider exploration to avoid recurrence and have increased risk for hereditary di...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-009-0022-6
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:The aim of this study was to investigate the factors for considering surgery on thyroid nodules that had non-diagnostic results on two consecutive cytology examinations. METHODS:A total of 104 thyroid nodules with two consecutive non-diagnostic cytology examinations in 104 patients were investigated. Nodule...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1397-8
更新日期：2012-03-01 00:00:00
abstract：BACKGROUND:Recent studies have shown a 7-15% lymph node (LN) metastasis rate in submucosal invasive colorectal cancer (SICC). Identifying risk factors for LN metastasis is crucial in selecting therapeutic modalities for SICC. We assessed the possibility of and the risk factors for LN metastasis in SICC. METHODS:We per...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9628-3
更新日期：2008-09-01 00:00:00
abstract：INTRODUCTION:This study assesses the incidence of missed pelvic injuries in the pre-hospital setting. METHODS:All blunt trauma patients (ISS ≥ 9) with pre-hospital suspicion of and/or radiologically proven pelvic fracture documented in the TraumaRegister DGU® (TR-DGU) of the German Trauma Society DGU (2002-2011) were ...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-016-3647-2
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:Surgical treatment of amiodarone-associated thyrotoxicosis (AAT) is effective although fewer than 100 cases have been reported world wide. MATERIALS AND METHODS:We reviewed 14 patients treated with total thyroidectomy by a single surgeon from 1998 to 2005. RESULTS:There were 11 male and 3 female patients w...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0673-x
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:Geriatric collaborative care models improve postoperative outcomes for older adults. However, there are limited data exploring how preoperative geriatric assessment may affect surgical cancellations. METHODS:This is a single-center retrospective cohort analysis. Patients enrolled in the Perioperative Optimi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05772-z
更新日期：2021-01-01 00:00:00
abstract：:The purpose of this study was to elucidate the function of the sphincter of Oddi (SO) in patients with juxtapapillary duodenal diverticula (JDDs). The SO function was evaluated by intraoperative biliary manometry in three groups of patients. Group 1 consisted of nine patients with JDDs and a dilated common bile duct (...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00308647
更新日期：1995-03-01 00:00:00
abstract：OBJECTIVE:The prognosis of Fournier's gangrene (FG) depends on early diagnosis and management. In this study, our objective was to identify the distinct features of FG that may influence the clinical outcome. METHODS:A retrospective chart review was performed in patients with a diagnosis of FG between January 1999 and...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0777-3
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Open surgical cricopharyngeal myotomy(CM) is considered standard of care for Zenker's diverticulum(ZD). Trans-oral CM has been described using a rigid stapling device for two decades; however, this remains problematic for severely kyphotic patients. This problem can be overcome with flexible endoscopy utiliz...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3442-0
更新日期：2016-06-01 00:00:00
abstract：BACKGROUND:Although mortality after liver resection has declined, posthepatectomy liver failure (PHLF) remains a major cause of operative mortality. To date there is not consensus on a definition for PHLF. However, there have been many efforts to define PHLF causing operative mortality. In the present study we sought t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-1959-z
更新日期：2013-05-01 00:00:00
abstract：BACKGROUND:The aim of this study was to evaluate the feasibility of liver resection in hepatocellular carcinoma (HCC) patients with preoperative renal dysfunction (RD). METHODS:Data from 735 patients undergoing primary liver resection for HCC between 2002 and 2014 were analyzed. Short- and long-term outcomes were comp...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4698-3
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:The appropriate surgical approach for hepatocellular carcinoma (HCC) patients of Child-Pugh class B is unclear. The aim of this study was to clarify the prognostic factors after hepatectomy in Child-Pugh class B patients and to delineate the selection criteria for hepatectomy. METHODS:One hundred fifty pati...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0929-y
更新日期：2011-04-01 00:00:00
abstract：OBJECTIVE:The aim of this study was to investigate the feasibility of digital defog technique in 3D laparoscopic surgery for right colon cancer. METHODS:Fifty patients with right colon cancer were divided into digital defogging group and control group. The intraoperative image clarity, the surgeon's anxiety, the time ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4402-z
更新日期：2018-06-01 00:00:00
