Abstract：
:Despite careful selection of cirrhotic patients with hepatocellular carcinoma (HCC), liver resection remains associated with a greater risk than in patients without underlying liver disease. In this study we assessed by multivariate analysis parameters associated with in-hospital mortality and morbidity in a selected group of 108 Child-Pugh A cirrhotic patients undergoing liver resection of HCC. The overall incidences of in-hospital deaths and postoperative complications were 8.3% and 48.1%, respectively. By univariate analysis, the preoperative serum alanine transferase (ALT) level (p = 0.001) and intraoperative transfusions (p = 0.01) were significantly associated with in-hospital death; however, only the serum ALT concentration was an independent risk factor. In-hospital mortality rates in patients whose serum ALT was below 2N (twofold the upper limit of the normal value), between 2N and 4N, and more than 4N were 3.9%, 13.0%, and 37.5%, respectively. An ALT level greater than 2N was predominantly observed in patients with a hepatitis C virus infection and significantly associated with histologic features of superimposed active hepatitis. Patients with an ALT level greater than 2N experienced an increased incidence of postoperative ascites (58% versus 32%, p = 0.01), kidney failure (16% versus 0%, p = 0.0003), and upper gastrointestinal bleeding (6.4% versus 0%, p = 0.02). These results indicate that the preoperative ALT level is a reliable predictor of in-hospital mortality and morbidity following liver resection in Child-Pugh A cirrhotic patients. Cirrhotic patients with ALT > 2N should undergo only a limited resection; if a larger resection is required, those patients should be considered for nonsurgical therapy or liver transplantation.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Noun R,Jagot P,Farges O,Sauvanet A,Belghiti Jdoi
10.1007/pl00012259subject
Has Abstractpub_date
1997-05-01 00:00:00pages
390-4; discussion 395issue
4eissn
0364-2313issn
1432-2323journal_volume
21pub_type
杂志文章abstract：BACKGROUND:Currently, there are no objective reports evaluating the quality of the South African surgical training. The aim of this study is to evaluate the current state of surgical training in South Africa from an external impartial point of view and to rate the experience of short-term supernumerary registrars and f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05034-7
更新日期：2019-09-01 00:00:00
abstract：BACKGROUND:The reported high incidence of 30-60% postoperative pain after an elective day surgical orchidopexy is undesirable. We evaluated the efficacy of our analgesic regimen for unilateral orchidopexy in preschool children performed as a day surgical procedure. METHODS:Between January 2004 and December 2006, 247 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9847-7
更新日期：2009-03-01 00:00:00
abstract：:This study was designed to investigate the optimal dose of garlic during long-term feeding and its preventive and therapeutic effects on colon cancer in rats induced by 1,2-dimethylhydrazine (DMH). A total of 240 male Sprague-Dawley rats were grouped and fed with either a basal or a garlic diet of different concentrat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00294738
更新日期：1995-07-01 00:00:00
abstract：INTRODUCTION:Rectus sheath hematoma is rare. It can present to physicians in many specialties, but invariably the surgeon is contacted regarding management. It is frequently difficult to diagnose, which can result in delay of treatment or unnecessary surgery. Its incidence is on the rise. METHODS:We present a series o...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0702-9
更新日期：2006-11-01 00:00:00
abstract：BACKGROUND:The efficacy and the indications of resection of synchronous or metachronous hepatic and pulmonary metastases from colorectal cancer (CRC) are controversial. This study retrospectively reviewed the cases of CRC patients who underwent both liver and lung resection to define the appropriate indications for sur...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1708-8
更新日期：2012-11-01 00:00:00
abstract：BACKGROUND:Medullary thyroid cancer (MTC) is characterized by early regional lymph node metastasis, the presence of which represents a critical obstacle to cure. At present no molecular markers have been successfully integrated into the clinical care of sporadic MTC. The present study was designed to evaluate TP53INP1 ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0395-6
更新日期：2010-04-01 00:00:00
abstract：BACKGROUND:Inflammation is integral to the pathogenesis of abdominal aortic aneurysm (AAA). This study examines preoperative biomarkers of systemic inflammation in patients undergoing open repair of intact and ruptured AAA. METHODS:One-hundred twelve patients were entered into a prospective observational study. Preope...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9014-6
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:Since the human genome has been sequenced many mysteries of cell biology have been unravelled, thereby clarifying the pathogenesis of several diseases, particularly cancer. In members of kindreds with certain hereditary diseases, it is now possible early in life to predict with great certainty whether or not...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-006-0616-1
更新日期：2007-03-01 00:00:00
abstract：:There have been a growing number of landmark randomized controlled trials published in the orthopedic literature over the past decade. These large-scale trials have had a substantial impact on informing clinical orthopedic practice globally. This review highlights a selected sample of such pivotal trials, across the s...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-019-04955-7
更新日期：2020-04-01 00:00:00
abstract：BACKGROUND:The majority of small bowel obstructions (SBO) are the result of adhesions caused by a previous abdominal operation. On rare occasions, adhesional SBO occurs in the absence of such an operation. Our objective was to describe the management, findings, and outcomes of unexplained adhesional SBO (UA-SBO) and ex...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0200-6
更新日期：2009-11-01 00:00:00
abstract：:Jaundice in patients of advanced carcinoma of the gallbladder requires palliation for the distressing symptoms of pruritus and cholangitis. Intrahepatic segment III duct cholangiojejunostomy is a means for alleviating the obstruction with malignant porta block. The authors reviewed their experience with this procedure...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900319
更新日期：1997-10-01 00:00:00
abstract：BACKGROUND:Diabetes mellitus (DM) is a known risk factor for worse outcomes after emergency abdominal surgery (EAS). However, it is unclear if the type of diabetes treatment (insulin or oral agents) has any effect on outcomes after EAS. METHODS:Matched cohort study utilizing the ACS NSQIP database. Patients with DM un...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3469-2
更新日期：2016-07-01 00:00:00
abstract：:Familial Mediterranean fever (FMF) also known as hereditary polyserositis, is an inherited disorder commonly found in Armenians, Turks, Arabs, Balkans, and Jews originating from North African countries. The diagnosis of FMF is based on clinical findings and family history, as no specific diagnostic test is yet availab...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF00348205
更新日期：1994-01-01 00:00:00
abstract：BACKGROUND:Beginning in 2004, a standardized medial-to-lateral approach was adopted in laparoscopic colorectal resection (LapCR) in our institution. The present study aimed to compare the outcomes of patients operated on by this approach with those who were operated on prior to the adoption of this technique. METHODS:...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0173-5
更新日期：2009-10-01 00:00:00
abstract：BACKGROUND:Laparoscopic cholecystectomy (LC) with common bile duct exploration (LCBDE) is nowadays a preferred one-stage treatment. However, the influence of complicated cholecystitis (CC) on LCBDE has rarely been addressed. In the present study we aimed to verify whether severe gallbladder inflammation would adversely...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1696-8
更新日期：2012-10-01 00:00:00
abstract：:Patients with short bowel syndrome (SBS) receiving total parenteral nutrition (TPN) have a high incidence of catheter-related sepsis, one of its major complications. The aim of this study was to correlate the length of remaining small bowel (RSB) with septic episodes related to the central venous catheter in a group o...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680010274
更新日期：2000-12-01 00:00:00
abstract：PURPOSE:This study was designed to assess the chronological change in health-related quality of life (HRQOL) following robot-assisted distal gastrectomy (RADG) for early gastric cancer (EGC) and to compare the HRQOL of the patients undergoing RADG with that of the general population. METHODS:Patients undergoing RADG f...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2390-1
更新日期：2014-05-01 00:00:00
abstract：:Uncontrolled bleeding from the cystic artery and its branches is a serious problem that may increase the risk of intraoperative lesions to vital vascular and biliary structures. On laparoscopic visualization anatomic relations are seen differently than during conventional surgery, so proper knowledge of the hepatobili...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00012372
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND:Small bowel obstruction (SBO) is characterized by a high rate of recurrence. In the present study, we aimed to compare the outcomes of patients managed either by conservative treatment or surgical operation for an episode of SBO. METHODS:The outcomes of all patients hospitalized at a single center for acute...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2733-6
更新日期：2014-12-01 00:00:00
abstract：:Hepatectomy with vascular reconstruction for biliary malignancy remains controversial. This study aimed to clarify the indications for surgery. Patients with advanced hilar bile duct cancer (HBDC) (n = 26) and gallbladder cancer (GBC) involving the hepatoduodenal ligament (n = 13) who underwent hepatectomy were enroll...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-6801-6
更新日期：2003-10-01 00:00:00
abstract：BACKGROUND:Critical illness disproportionately affects people in low-income countries (LICs). Efforts to improve critical care in LICs must account for differences in demographics and infrastructure compared to high-income settings. Part of this effort includes the development and validation of intensive care unit (ICU...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05078-9
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:The evolution of diagnostic procedures has resulted in an increase in early detection of pathologically T1 (pT1) colorectal cancer (CRC). However, the risk factors affecting long-term outcomes of patients with pT1 CRCs have been unclear. The aim of the present study was to identify risk factors for postopera...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1378-y
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:Trauma contributes more than ten percent of the global burden of disease. Initial assessment and resuscitation of trauma patients often requires rapid diagnosis and management of multiple concurrent complex conditions, and errors are common. We investigated whether implementing a trauma care checklist would ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3759-8
更新日期：2017-04-01 00:00:00
abstract：:During the period 1979 to 1989, 0.1% of all cases of acute appendicitis at our institution occurred soon after another operative procedure. The interval between primary operation and appendectomy was 5 to 31 days (mean, 14 days). Signs and symptoms did not differ from those of classical acute appendicitis. Duration of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01675654
更新日期：1991-07-01 00:00:00
abstract：:Local recurrence in differentiated and medullary thyroid carcinoma develops frequently from metastatic infiltration of cervical lymph nodes. Despite an aggressive surgical approach, postoperative calcitonin levels as biochemical evidence for residual cancer cells remain often elevated in patients with medullary thyroi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0197-y
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND:The specific definition of central hepatectomy (CH) (i.e., resection of segments 4-5-8 ± 1) is not uniformly used, resulting in conflicting comparisons with the more commonly performed extended hepatectomy (EH). The study aimed to compare, using propensity score matching (PSM) analysis, the incidence of post...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3584-0
更新日期：2016-11-01 00:00:00
abstract：:The imaging characteristics of diagnostic ultrasound (US) are determined by the ultrasonic properties of tissue. The velocity of propagation of US and the attenuation are the 2 most important parameters. These determine the frequency with which the tissues may be imaged, which in turn sets a fundamental limit on the a...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910026
更新日期：2000-02-01 00:00:00
abstract：BACKGROUND:Few studies have focused on the risk factors for failure to achieve fascial closure after use of negative-pressure wound therapy (NPWT) in an open abdomen (OA). We aimed at analyzing possible risk factors for failure of fascial closure and the risk of fistulas after nontrauma lower gastrointestinal (GI) trac...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2360-7
更新日期：2014-04-01 00:00:00
abstract：BACKGROUND:Adhesions due to the reactions caused by the grafts used in primary vascular operations can lead to various problems when a secondary operation is necessary. These problems include bleeding, injuries to neighboring organs, and complications occurring due to a prolonged operation. We investigated the effects ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0750-1
更新日期：2006-09-01 00:00:00
abstract：BACKGROUND:Right hepatectomy with caudate lobectomy (RHx) is considered an appropriate procedure for Bismuth type I/II perihilar cholangiocarcinoma in terms of its anatomical and oncological aspect. However, validity of left hepatectomy with caudate lobectomy (LHx) concomitant with arterial resection and reconstruction...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4833-1
更新日期：2019-03-01 00:00:00
