Abstract:
BACKGROUND:The evolution of diagnostic procedures has resulted in an increase in early detection of pathologically T1 (pT1) colorectal cancer (CRC). However, the risk factors affecting long-term outcomes of patients with pT1 CRCs have been unclear. The aim of the present study was to identify risk factors for postoperative recurrence and overall survival in patients with pT1 CRC. METHODS:Between January 1990 and January 2003, a total of 284 patients with pT1 CRC underwent radical surgery in the authors' institution. The impact of clinicopathological factors on postoperative recurrence and overall survival was estimated by univariate and multivariate analysis. RESULTS:The median follow-up period was 55 months (interquartile range: 47.1 months). Postoperative recurrence occurred in 8 (2.8%) patients. The overall 5-year and 10-year disease-free survival rates were 98.4 and 92.7%. Multivariate analysis showed the presence of lymphatic invasion only was an independent risk factor for postoperative recurrence in pT1 CRC patients (hazard ratio: 11.622; P = 0.003). The 5-year and 10-year disease-free survival rates of the patients in N-ly- group, the N-ly + group, and the N+ group were 99.5%/98.2% and 96.3%/75.2%, and 93.3%/93.3%, respectively. Additionally, 4 of the 8 recurrences were found more than 5 years after the operation. CONCLUSIONS:Lymphatic invasion was an independent risk factor for recurrence in pT1 CRC patients.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Iida S,Hasegawa H,Okabayashi K,Moritani K,Mukai M,Kitagawa Ydoi
10.1007/s00268-011-1378-ysubject
Has Abstractpub_date
2012-02-01 00:00:00pages
424-30issue
2eissn
0364-2313issn
1432-2323journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Acute appendicitis is the most common reason for abdominal surgery in young adults and children. Open appendectomy is still the treatment often chosen because it is simple, safe, and effective. Our aim was to study whether cosmetic results of appendectomy wounds are better after using continuous absorbable i...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-013-2396-8
更新日期:2014-05-01 00:00:00
abstract::Pepsinogen C is a proteolytic enzyme involved in the digestion of proteins in the stomach; it is also synthesized by a significant percentage of female breast carcinomas. In addition, it has been demonstrated that pepsinogen C is one of the few proteins induced by androgens in breast carcinoma cells. Here we evaluate ...
journal_title:World journal of surgery
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:1994-09-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1175-7
更新日期:2011-09-01 00:00:00
abstract:INTRODUCTION:The impact of diabetes mellitus (DM) on outcomes in patients undergoing emergency laparotomy for adhesive small bowel obstruction (ASBO) remains unknown. METHODS:Low-risk (ASA class of I and II) patients requiring emergency operation for ASBO were identified using the ACS NSQIP database. Propensity score ...
journal_title:World journal of surgery
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abstract:BACKGROUND:Surgical care is emerging as a crucial issue in global public health. Methodology is needed to assess the impact of surgical care from a public health perspective. METHODS:A consensus opinion of a group of surgeons, anesthesiologists, and public health experts was established regarding the methodology for e...
journal_title:World journal of surgery
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更新日期:2010-03-01 00:00:00
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journal_title:World journal of surgery
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journal_title:World journal of surgery
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更新日期:2007-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:1991-11-01 00:00:00
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journal_title:World journal of surgery
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更新日期:2010-04-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2018-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2378-x
更新日期:2014-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1007/BF02067069
更新日期:1992-11-01 00:00:00
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journal_title:World journal of surgery
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更新日期:2002-01-01 00:00:00
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journal_title:World journal of surgery
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更新日期:2008-01-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00268-014-2876-5
更新日期:2015-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05648-2
更新日期:2020-09-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01658430
更新日期:1989-11-01 00:00:00
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pub_type: 杂志文章
doi:10.1007/s00268-012-1585-1
更新日期:2012-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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pub_type: 杂志文章,随机对照试验
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更新日期:2008-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4796-2
更新日期:2019-02-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1318-x
更新日期:2012-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2013-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3964-0
更新日期:2017-08-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:2007-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2020-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:1998-08-01 00:00:00