Abstract：
BACKGROUND:The aims of this study were to investigate predictive factors for microscopic portal venous invasion (mPVI) in hepatocellular carcinoma (HCC) and whether anatomical liver resection (ALR) was useful in such cases. METHODS:We analyzed 852 patients with HCC without macroscopic portal venous invasion who were treated at our hospital between January 1990 and May 2014. These patients were stratified into a microscopic portal venous invasion group (mPVI group; n = 153) and non-microscopic portal venous invasion group (NmPVI group; n = 699). RESULTS:PIVKA-II ≥100 mAU/ml, a tumor size ≥5 cm, a confluent lesion, and poor differentiation were found to be independent risk factors for mPVI. Among the mPVI group who had single HCC under 5 cm, serum albumin level <4.0 g/dl, PIVKA-II ≥100 mAU/ml, a positive surgical margin, and non-ALR (NALR) were independent unfavorable prognostic factors for overall survival (OS). PIVKA-II ≥100 mAU/ml, a positive surgical margin and NALR were independent unfavorable prognostic factors for relapse-free survival (RFS). ALR was significantly favorable factor for both OS and RFS of the mPVI group who had single HCC under 5 cm. CONCLUSIONS:Even if no portal venous invasion is detectable in HCC patients preoperatively, a PIVKA-II ≥100 mAU/ml, tumor size ≥5 cm, and a confluent lesion indicate a high risk of mPVI. ALR should be considered for the patients with these characteristics because it is a favorable prognostic factor in these cases with mPVI.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Shimada S,Kamiyama T,Yokoo H,Orimo T,Wakayama K,Einama T,Kakisaka T,Kamachi H,Taketomi Adoi
10.1007/s00268-017-3964-0subject
Has Abstractpub_date
2017-08-01 00:00:00pages
2087-2094issue
8eissn
0364-2313issn
1432-2323pii
10.1007/s00268-017-3964-0journal_volume
41pub_type
杂志文章abstract：:The effects of splenectomy in 41 patients managed from 1982 to 1995 at Sher-i-Kashmir Institute of Medical Sciences, Srinagar (Jammu and Kashmir), India, were studied. Immune thrombocytopenic purpura (ITP) was the main indication for therapeutic splenectomy among all the hematologic disorders. The mean age was 30 year...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910017
更新日期：2000-01-01 00:00:00
abstract：BACKGROUND:Inguinal hernia is thought to be common in rural Ghana, though no recent data exist on hernia prevalence in the country. This information is needed to guide policy and increase access to safe hernia repair in Ghana and other low-resource settings. METHODS:Adult men randomly selected from the Barekese sub-di...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3335-7
更新日期：2016-04-01 00:00:00
abstract：:The role of the tumor suppressor gene p53 and proto-oncogenes mdm-2, waf-1,and bcl-2 in sporadic colorectal carcinoma (CRC) has been well investigated. However, little is known about the role of these genes in the development of ulcerative colitis-associated colorectal carcinoma (CAC). Colectomy specimens from patient...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0237-7
更新日期：2002-03-01 00:00:00
abstract：BACKGROUND:The use of the Harmonic Scalpel (HS) for cystic duct ligation began with little data about its efficacy or safety. On the other hand, there is not any literature available about the use of PlasmaKinetic Sealer (PK) for closing the cystic duct in laparoscopic cholecystectomy (LC). Therefore, this study was de...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0819-3
更新日期：2011-04-01 00:00:00
abstract：PURPOSE:Restorative surgery for rectal cancer is usually criticized by its functional outcomes. The aim of this study is to assess the efficacy "taeniectomy" pouch in comparison with transverse coloplasty pouch. STUDY DESIGN:This was a prospective controlled study. Most patients who were candidate for low rectal resec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-04890-z
更新日期：2019-04-01 00:00:00
abstract：:The purpose of this study was to evaluate the surgical outcome of completion thyroidectomy in patients with presumed unilateral well-differentiated thyroid cancer (WDTC). The medical records of all patients having had unilateral thyroid lobectomy for WDTC, who subsequently underwent completion thyroidectomy, were revi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067365
更新日期：1992-07-01 00:00:00
abstract：BACKGROUND:The goal of the present study was to evaluate the effects of preoperative oral carbohydrate supplementation (OCH) on the postoperative metabolic stress response of patients undergoing elective abdominal surgery. METHODS:The study was designed as a controlled, prospective, cohort study including 38 patients ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1590-4
更新日期：2012-08-01 00:00:00
abstract：:We evaluated the morbidity associated with primary closure by interrupted subcuticular absorbable sutures following emergency appendectomy. In a prospective clinical trial over a 12-month period, 216 children who underwent emergency appendectomy had skin closure using subcuticular interrupted absorbable polyglactin 4-...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900007
更新日期：1996-01-01 00:00:00
abstract：OBJECTIVE:The prognosis of Fournier's gangrene (FG) depends on early diagnosis and management. In this study, our objective was to identify the distinct features of FG that may influence the clinical outcome. METHODS:A retrospective chart review was performed in patients with a diagnosis of FG between January 1999 and...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0777-3
更新日期：2006-09-01 00:00:00
abstract：:It is difficult to evaluate precisely the effects of one individual on an entire discipline such as surgery. Indeed, it is impossible to do so when such a discipline spans so vast a country as the United States of America. Nevertheless, as a mountain peak can be seen from afar, so may one perceive the influence of man...
journal_title：World journal of surgery
pub_type： 传,历史文章,杂志文章
doi：10.1007/s002689900357
更新日期：1998-01-01 00:00:00
abstract：:Ambulatory laparoscopic cholecystectomy is an established practice in our institution, with an experience of more than 800 cases. The present study is conducted to evaluate the contemporary outcomes of day-case laparoscopic cholecystectomy in the setting of a major teaching hospital. A retrospective analysis of 200 pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6264-1
更新日期：2002-09-01 00:00:00
abstract：AIM:To investigate the learning curve and perioperative outcomes of single-site robotic cholecystectomy during the first 102 cases by a single surgeon. MATERIALS AND METHODS:A retrospective review of a prospectively maintained database was performed on the first 102 cases of single-site robotic cholecystectomy. Patien...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3135-0
更新日期：2015-10-01 00:00:00
abstract：:Pectus excavatum (PE) is one of the most common anomalies of childhood. It occurs in approximately 1 in every 400 births, with males afflicted 5 times more often than females. PE is usually recognized in infancy, becomes much more severe during adolescent growth years, and remains constant throughout adult life. Sympt...
journal_title：World journal of surgery
pub_type： 社论,评审
doi：10.1007/s00268-003-7025-5
更新日期：2003-05-01 00:00:00
abstract：BACKGROUND:Laparoscopic hepatectomy (LH) is established as a safe and feasible treatment option for liver tumors. However, whether the adoption of laparoscopic approach for malignant tumors, such as hepatocellular carcinoma (HCC), will compromise the long-term result is still unknown. This study was designed to evaluat...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1212-6
更新日期：2011-10-01 00:00:00
abstract：BACKGROUND:The goal of the present study was to determine the frequency, mode of presentation, and need for reoperation in the treatment of recurrent inguinal hernia at Liaquat University Hospital, Jamshoro, Sindh, Pakistan. METHODS:This descriptive, cross-sectional study was conducted over a period of four years, fro...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1897-1
更新日期：2013-03-01 00:00:00
abstract：BACKGROUND:Several studies have demonstrated that laparoscopic surgery is safe and effective for urgent and emergent colectomy in adulthood. The aim of the present study was to evaluate the feasibility of laparoscopic colectomy for children in emergent settings. METHODS:Between March 2008 and August 2011, 10 consecuti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1585-1
更新日期：2012-08-01 00:00:00
abstract：BACKGROUND:Surgical care is not uniformly available worldwide. Inequities in surgical care and access may also vary within countries, and the present study aimed to explore these disparities in Pakistan. METHODS:The National Health Survey of Pakistan was analyzed. The proportion of people with a history of abdominal s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1732-8
更新日期：2013-07-01 00:00:00
abstract：:Enteral nutrition (EN) and total parenteral nutrition (TPN) may provide life-sustaining therapy for surgical patients. The duration of nutritional therapy (enteral or parenteral) implies distinct access routes. We review the main aspects related to access routes for nutrient delivery. The enteral route, whenever feasi...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010264
更新日期：2000-12-01 00:00:00
abstract：BACKGROUND:Recurrent laryngeal nerve palsy (RLNP) is one of the most common complications after thyroidectomy. We aim to evaluate the role of intraoperative corticosteroids in preventing or treating postoperative RLNP. MATERIALS AND METHODS:We conducted a prospective study of 295 patients who underwent either total lo...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0399-9
更新日期：2006-03-01 00:00:00
abstract：:This paper describes a model humanitarian mission to Guyana; it illustrates the value of excellent ongoing care in collaboration with local physicians and surgeons, cooperation with local government and medical officials, and frequent periodic follow-up missions (always to the same hospital, working with the same staf...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3049-x
更新日期：2015-08-01 00:00:00
abstract：:The expression of Fas ligand on tumor cells may counterattack the host's immunity and worsen the prognosis. Knowledge of the prognostic impact of Fas ligand on patients with hepatocellular carcinoma (HCC) after hepatectomy is still limited. Fas ligand expression in HCCs was examined in 59 patients who underwent hepate...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7254-2
更新日期：2004-08-01 00:00:00
abstract：:It is a fact that without ideas there is nothing. Without ideas and without innovations there is nothing to test. An interesting, often asked question is: How are ideas, innovations born? It is surely correct that people giving birth to ideas have special characteristics. These creative people are different but still ...
journal_title：World journal of surgery
pub_type： 历史文章,杂志文章
doi：10.1007/s002689900577
更新日期：1999-08-01 00:00:00
abstract：:Carnitine, an important carrier of free fatty acid that is transported into mitochondria for beta-oxidation, was thought to be one of the key factors in the regulation of liver regeneration. If the carnitine content is insufficient in the hepatocyte, it might impair the energy substrate's transport and the energy char...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900347
更新日期：1998-01-01 00:00:00
abstract：BACKGROUND:Surgical treatment of amiodarone-associated thyrotoxicosis (AAT) is effective although fewer than 100 cases have been reported world wide. MATERIALS AND METHODS:We reviewed 14 patients treated with total thyroidectomy by a single surgeon from 1998 to 2005. RESULTS:There were 11 male and 3 female patients w...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-0673-x
更新日期：2006-11-01 00:00:00
abstract：INTRODUCTION:Parathyroid cysts are rare but clinically significant lesions. They can be functional, mistaken for a thyroid cyst, and/or managed nonoperatively on occasion. METHODS:We identified seven patients (1 male, 6 females) with the diagnosis of parathyroid cyst from 1998 to 2003. RESULTS:Altogether, 33% of the ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0748-8
更新日期：2007-01-01 00:00:00
abstract：:It is a fundamental clinical observation that wounds do not heal in tissue that does not bleed, and they almost always heal in tissue that bleeds extensively. Continuous supply of oxygen to the tissue through microcirculation is vital for the healing process and for resistance to infection. Evaluation of tissue perfus...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-003-7398-5
更新日期：2004-03-01 00:00:00
abstract：BACKGROUND:We aimed to describe the pattern of solid organ injuries (SOIs) and analyze the characteristics, management and outcomes based on the multiplicity of SOIs. METHODS:A retrospective study in a Level 1 trauma center was conducted and included patients admitted with blunt abdominal trauma between 2011 and 2014....
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4087-3
更新日期：2017-11-01 00:00:00
abstract：:Subfascial elimination of incompetent perforating veins is the most effective therapeutic principle in the treatment of trophic skin disorders associated with varicosis. A recently developed endoscopic technique allows accurate sectioning of perforating veins with direct observation of the veins and minor trauma. From...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067007
更新日期：1992-09-01 00:00:00
abstract：:Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010228
更新日期：2000-11-01 00:00:00
abstract：BACKGROUND:The aim of this study was to analyze the prognostic factors associated with long-term outcome after liver resection for colorectal metastases. The retrospective analysis included 297 liver resections for colorectal metastases. METHODS:The variables considered included disease stage, differentiation grade, s...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9285-y
更新日期：2008-01-01 00:00:00
