Abstract:
BACKGROUND:Laparoscopic hepatectomy (LH) is established as a safe and feasible treatment option for liver tumors. However, whether the adoption of laparoscopic approach for malignant tumors, such as hepatocellular carcinoma (HCC), will compromise the long-term result is still unknown. This study was designed to evaluate the long-term results of LH compared with a cohort of case-matched open hepatectomy (OH). METHODS:Thirty-three patients who underwent LH for HCC in our institution between June 2004 and March 2010 were recruited. A group of 50 patients who underwent OH for HCC during the same period was identified by matching to magnitude of operation, size of tumor, site of tumor, and the absence of concomitant local ablation or major procedure. The perioperative outcomes, disease recurrence, and survival of the two groups of patients were determined and compared. RESULTS:LH resulted in less operative complications (6.1% vs. 24%, P = 0.033) and shorter median hospital stay (5 vs. 7 days, P < 0.0005) but required longer operative time compared with OH (225 vs. 195 min, P = 0.019). There was no difference between LH and OH in recurrence rate (45.5% vs. 38%, P = 0.499). The 1-, 3-, and 5-year overall survival were 86.9%, 81.8%, and 76% for LH and 98%, 80.6%, and 76.1% for OH respectively (P = 0.646). The 1-, 3-, and 5-year disease-free survival were 78.8%, 51%, and 45.3% for LH and 69.2%, 55.9%, and 55.9% for OH, respectively (P = 0.849). CONCLUSIONS:Compared with OH, LH for HCC has similar long-term outcomes, but it has short-term advantages of less operative complications and shorter hospital stay.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lee KF,Chong CN,Wong J,Cheung YS,Wong J,Lai Pdoi
10.1007/s00268-011-1212-6subject
Has Abstractpub_date
2011-10-01 00:00:00pages
2268-74issue
10eissn
0364-2313issn
1432-2323journal_volume
35pub_type
杂志文章abstract::There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900016
更新日期:1996-01-01 00:00:00
abstract::Although peptic gastroduodenal ulcers are rarely treated surgically today, when surgery is required a laparoscopic approach is possible with its well known advantages. The most widely used technique is vagotomy by various modalities. Training in laparoscopy requires good instrumentation to avoid complications. Vagotom...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:2000-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2020-04-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05635-7
更新日期:2020-10-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7588-9
更新日期:2005-04-01 00:00:00
abstract:BACKGROUND:The estimation of physiologic ability and surgical stress (E-PASS) has been used to produce a numerical estimate of expected mortality and morbidity after elective gastrointestinal surgery. The aim of this study was to validate E-PASS in a selected cohort of patients requiring liver resections (LR). METHODS...
journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2009-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3391-z
更新日期:2016-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01671147
更新日期:1989-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1536-x
更新日期:2012-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3107-4
更新日期:2015-10-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689910063
更新日期:2000-04-01 00:00:00
abstract:BACKGROUND:The Lancet recently sponsored a commission examining the role of surgery in global health. There is a paucity of published information on the cost-effectiveness of surgery in low- and middle-income countries, a key metric in the prioritisation of limited resources. METHODS:All patients undergoing emergency ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3271-6
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The splintering of general surgery into subspecialties in the past decade has brought into question the relevance of a continued emphasis on traditional general surgical training. With the majority of trainees now expressing a preference to subspecialise early, this study sought to identify if the requiremen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2890-7
更新日期:2015-02-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-015-3246-7
更新日期:2016-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:2000-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3867-5
更新日期:2017-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9708-4
更新日期:2008-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900631
更新日期:1999-11-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0256-3
更新日期:2010-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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journal_title:World journal of surgery
pub_type: 杂志文章
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journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:1996-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-006-0016-6
更新日期:2006-12-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2015-08-01 00:00:00
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journal_title:World journal of surgery
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更新日期:2012-03-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2004-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2018-11-01 00:00:00
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journal_title:World journal of surgery
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更新日期:2001-06-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:1994-01-01 00:00:00