Abstract：
:A group of 105 consecutive patients with venographically proved major acute deep vein thrombosis (DVT) were randomized in an open prospective study to evaluate the comparative efficacy and safety of a fixed dose of subcutaneous low-molecular-weight heparin (LMWH) and warfarin for the prevention of recurrent venous thromboembolism. Four patients developed venographically proved recurrent DVT during the 3 months of treatment: three in the LMWH group and one in the warfarin group. Nonfatal pulmonary embolism occurred in two patients in the LMWH group and in one in the warfarin group. Five of the 55 patients (10%) in the warfarin group and none of the 50 patients in the LMWH developed bleeding complications (two-tailed Fisher exact test, p = 0.06). A preliminary assessment of the costs indicated that treatment with LMWH was less expensive by Pounds 900 per patient than warfarin. In conclusion, the fixed daily dose of LMWH and the adjusted dose of warfarin therapy were of similar efficacy in preventing recurrence of DVT. However, warfarin therapy, despite strict laboratory control, is associated with more frequent side effects and is expensive. Another study with a higher dose of LMWH is recommended.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Das SK,Cohen AT,Edmondson RA,Melissari E,Kakkar VVdoi
10.1007/s002689900081subject
Has Abstractpub_date
1996-06-01 00:00:00pages
521-6; discussion 526-7issue
5eissn
0364-2313issn
1432-2323journal_volume
20pub_type
临床试验,杂志文章,随机对照试验abstract：BACKGROUND:Minimally invasive radio-guided parathyroidectomy (MIRP) has been embraced as an acceptable therapeutic approach to primary hyperparathyroidism. Preoperative sestamibi scanning has facilitated this technique. Here we evaluate the addition of a rapid intraoperative parathyroid hormone (iPTH) assay for patient...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0293-5
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Existing data suggest a large burden of surgical conditions in low- and middle-income countries (LMICs). However, surgical care for children in LMICs remains poorly understood. Our goal was to define the hospital infrastructure, workforce, and delivery of surgical care for children across Somaliland and prov...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05079-8
更新日期：2019-11-01 00:00:00
abstract：:We determined the relative value of the metastatic colorectal cancer doubling time as a predictor of recurrence and survival after hepatectomy in comparison with other established predictors. Consecutive patients who underwent hepatic resection ( n = 144) for colorectal cancer liver metastases were studied retrospecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7088-3
更新日期：2004-03-01 00:00:00
abstract：:A family history of colorectal cancer is a known risk factor for the disease. As a result of different study designs from different populations, the strength of this association varies in the literature. We intended to define the incidence and the risk predictors in first-degree relatives of patients with colorectal c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900217
更新日期：1997-02-01 00:00:00
abstract：BACKGROUND:Total mesorectal excision (TME) and preoperative chemoradiation therapy (PCRT) for rectal cancer are used sequentially in our center. The aim of this study was to evaluate survival of patients with stage II/III rectal cancer chronologically and to determine whether therapeutic advances associated with TME an...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2168-5
更新日期：2013-11-01 00:00:00
abstract：:The geographic distribution of duodenal ulcer and its characteristics in rural areas of high incidence in developing countries are reviewed. The choice of surgical procedures is discussed in light of the bulky diet and nutritional problems of these countries. A vagotomy procedure is advised for duodenal ulcer and a B...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01654731
更新日期：1977-01-01 00:00:00
abstract：BACKGROUND:Sentinel lymph node biopsy (SLNB) plays an essential role in the evaluation of lymph node (LN) metastasis status and the extent of LN dissection in gastric cancer. The aim of our study was to perform a systematic review and meta-analysis for corresponding identification rate and sensitivity of different SLNB...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-020-05900-9
更新日期：2021-01-03 00:00:00
abstract：:Acute acalculous cholecystitis (AAC) is a well known complication in severely traumatized patients. Existing data of AAC originate from retrospective analyses and episodic case reports. In a prospective study 45 polytraumatized patients admitted to our intensive care unit from January 1989 to June 1990 were clinically...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067089
更新日期：1992-11-01 00:00:00
abstract：BACKGROUND:We sought to assess the status of availability of technology for trauma care in a state in India and to identify factors contributing to both adequate levels of availability and to deficiencies. We also sought to identify potential solutions to deficiencies in terms of health system management and product de...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2805-7
更新日期：2015-02-01 00:00:00
abstract：BACKGROUND:Complications following esophagectomy are a significant source of morbidity. The aim of this study was to investigate the utility of the neutrophil:lymphocyte ratio (NLR) in the early identification of complications following esophagectomy, as compared to other routinely available parameters. METHODS:We per...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3427-z
更新日期：2016-06-01 00:00:00
abstract：INTRODUCTION:Cardiovascular dysfunction (CVD) is a well-recognized complication in patients with hyperthyroidism and is the major cause of mortality. Very few studies have compared the outcome of CVD following different treatment modalities. In this study we intended to compare treatment modalities (antithyroid drugs v...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-4571-4
更新日期：2018-05-01 00:00:00
abstract：:Dissemination of new surgical knowledge, skills, and techniques across the wide spectrum of practicing surgeons in the community is often difficult and slow. This is even more problematic in countries such as Canada, where geographic distances separate a large portion of community surgeons from the large teaching cent...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9076-5
更新日期：2007-08-01 00:00:00
abstract：:TraumAID is a computer-based decision aid that uses decision rules and logical deduction to generate management plans for the initial definitive management of injured patients; its use is currently confined to assessing penetrating thoracoabdominal injuries in nonpregnant adults. These management plans were compared t...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s00268-001-0263-5
更新日期：2002-05-01 00:00:00
abstract：BACKGROUND:Mutations in BRCA1 and BRCA2 confer an increased risk to breast and other cancers, but to date there have only been limited numbers of studies of BRCA1- and BRCA2-associated cancers among Asians. Malaysia is a multiracial country with three main races: Malays, Chinese, Indians. We determined whether tumor pa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0146-8
更新日期：2009-10-01 00:00:00
abstract：:Chondrosarcomas of the head and neck are uncommon. Over a 35-year period (1950-1985) at our institution, 557 patients had an established diagnosis of chondrosarcoma. In 28 (5%) of these patients, the tumor was located in the head and neck region. A retrospective analysis was performed in an attempt to accurately defin...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF02067021
更新日期：1992-09-01 00:00:00
abstract：BACKGROUND:This study was undertaken to determine the efficacy of the clinical indications for performing staging laparoscopy for locally advanced gastric cancer to detect peritoneal metastasis or positive cytology findings. METHODS:The study included 231 patients with T4 gastric cancer without hematogenous or clinica...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-1290-5
更新日期：2011-12-01 00:00:00
abstract：:We retrospectively reviewed postoperative complications in 105 patients with hilar cholangiocarcinoma who underwent hepatectomy at Nagoya University Hospital from January 1990 through March 1999. Of the 105 subjects, 97 (92.4%) underwent resection of two or more Healey's segments of the liver. Combined portal vein res...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0110-8
更新日期：2001-10-01 00:00:00
abstract：:During the period 1979 to 1989, 0.1% of all cases of acute appendicitis at our institution occurred soon after another operative procedure. The interval between primary operation and appendectomy was 5 to 31 days (mean, 14 days). Signs and symptoms did not differ from those of classical acute appendicitis. Duration of...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01675654
更新日期：1991-07-01 00:00:00
abstract：:The success of parathyroid surgery is determined by the identification and removal of all parathyroid tumors. Parathyroid tumors accumulate and retain 2-methoxyisobutylisonitrile (MIBI) labeled with technetium-99m. Intravenous injection of this radiopharmacon prior to parathyroid surgery allows identification of parat...
journal_title：World journal of surgery
pub_type： 临床试验,杂志文章
doi：10.1007/s002689900427
更新日期：1998-06-01 00:00:00
abstract：BACKGROUND:Connective tissue growth factor (CTGF) expression changes variously in different human malignancies. The role of CTGF in hepatocellular carcinoma (HCC) is still not clear. The purpose of this study was to investigate the role of serum CTGF in patients with HCC and its correlation with HCC angiogenesis. METH...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0648-4
更新日期：2010-10-01 00:00:00
abstract：BACKGROUND:Approximately 30% of patients with thyroid nodules have indeterminate or suspicious fine-needle aspiration (FNA) biopsy results. Because their risk of cancer is approximately 20%, these patients undergo thyroidectomy. We hypothesized that genes that regulate cell-cycle progression would be differentially exp...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0308-2
更新日期：2006-05-01 00:00:00
abstract：PURPOSE:Advanced Trauma Life Support (ATLS®) is one of the world's best-known training programs for medical providers. Revisions of the ATLS manual have been evidence based for a number of years. In 2011, a level 3 (S3) evidence- and consensus-based guideline on the treatment of patients with severe and multiple injuri...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-3063-z
更新日期：2015-08-01 00:00:00
abstract：:Genital manifestations of lymphatic filariasis (genital LF) are a significant cause of disfigurement and disability in the developing world. Surgery is the standard treatment; however, definitive publications are lacking and best practice remains unclear. An exhaustive search strategy using keyword and subject heading...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-015-3220-4
更新日期：2015-12-01 00:00:00
abstract：BACKGROUND:Up to 50% of patients in intensive care units develop intraabdominal hypertension (IAH) in the course of medical treatment. If not detected on time and treated adequately, IAH may develop into an abdominal compartment syndrome (ACS) which is associated with a high mortality rate. Patients undergoing cardiac ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05917-0
更新日期：2021-01-22 00:00:00
abstract：:In some patients, bile ducts of segments 2 and 3 (B2 and B3) run caudally to the umbilical portion of the left portal vein (UP)--an infraportal course. We aimed to evaluate the frequency and clinical implications of this variation. Between January 1992 and October 2000, 108 patients underwent resection for hilar chola...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6544-9
更新日期：2002-12-01 00:00:00
abstract：:From the earliest description of dysphagia relieved by dilatation with a whalebone in 1674 we have witnessed the evolution of esophageal function testing from the conventional manometry to the high-resolution manometry (HRM) and esophageal topography pressure plotting that have led to the revised Chicago classificatio...
journal_title：World journal of surgery
pub_type： 历史文章,杂志文章
doi：10.1007/s00268-014-2939-7
更新日期：2015-07-01 00:00:00
abstract：INTRODUCTION:Mechanical bowel obstruction cases constitute an important place in emergency health care services. In this study, bowel obstructions caused by intra-abdominal tumors were compared with those without tumoral causes. PATIENTS AND METHODS:A total of 155 cases of mechanical bowel obstruction diagnosed were r...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0440-z
更新日期：2006-07-01 00:00:00
abstract：:Surgical management of hepatic hydatid disease has been associated with an overall local recurrence rate of approximately 10%. Local recurrence is rarely seen following complete resection of an intact cyst and is usually the result of spillage of live parasites or leaving a residual cyst wall containing germinal epith...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680020011
更新日期：2001-01-01 00:00:00
abstract：:Local recurrence in differentiated and medullary thyroid carcinoma develops frequently from metastatic infiltration of cervical lymph nodes. Despite an aggressive surgical approach, postoperative calcitonin levels as biochemical evidence for residual cancer cells remain often elevated in patients with medullary thyroi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0197-y
更新日期：2002-02-01 00:00:00
abstract：BACKGROUND:Few studies have focused on the risk factors for failure to achieve fascial closure after use of negative-pressure wound therapy (NPWT) in an open abdomen (OA). We aimed at analyzing possible risk factors for failure of fascial closure and the risk of fistulas after nontrauma lower gastrointestinal (GI) trac...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-2360-7
更新日期：2014-04-01 00:00:00
