Abstract:
:It is a fundamental clinical observation that wounds do not heal in tissue that does not bleed, and they almost always heal in tissue that bleeds extensively. Continuous supply of oxygen to the tissue through microcirculation is vital for the healing process and for resistance to infection. Evaluation of tissue perfusion and oxygenation is important in all types of wound patients. Monitoring systems should measure the hemodynamic situation and the ability of the cardiovascular system to deliver an adequate volume of oxygen to meet the metabolic demands of the peripheral tissue. Oxygen therapy is important in relation to both healing and resistance to infections. External factors have been shown to significantly decrease the peripheral oxygen supply, and supplementary perioperative oxygen to reduce the surgical wound infection rate by one- half in patients undergoing colorectal resection. Hyperbaric oxygen therapy may be beneficial in situations where the nutritive flow and oxygen supply to the healing tissue are compromised by local injury, and particularly if anaerobic infection is present. However, the definitive proof for the effect and indications of this therapy in wound healing still has to be established. It can be concluded that adequate delivery of oxygen to the wound tissue is vital for optimal healing and resistance to infection. Assessment of perfusion and oxygenation is essential for the wound patient, as well as the treating personnel. The indication for hyperbaric oxygen treatment still needs to be defined. During wound healing the continuity and function of the damaged tissue are re-established. This is only possible through a restoration of the microcirculation and thereby the nutrition to the tissue. The main component of the nutrition is oxygen, which is critically important for healing a wound by production of granulation tissue and for ensuring resistance against infection. This has been shown experimentally, but recently a short period of supplementary oxygen has been shown to decrease wound complications in clinical practice as well.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Gottrup Fdoi
10.1007/s00268-003-7398-5keywords:
subject
Has Abstractpub_date
2004-03-01 00:00:00pages
312-5issue
3eissn
0364-2313issn
1432-2323journal_volume
28pub_type
杂志文章,评审abstract:BACKGROUND:Minimally invasive radio-guided parathyroidectomy (MIRP) has been embraced as an acceptable therapeutic approach to primary hyperparathyroidism. Preoperative sestamibi scanning has facilitated this technique. Here we evaluate the addition of a rapid intraoperative parathyroid hormone (iPTH) assay for patient...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0293-5
更新日期:2006-02-01 00:00:00
abstract:BACKGROUND:A majority of patients with end-stage renal disease suffer from secondary hyperparathyroidism, which is associated with osteoporosis and cardiovascular disease. Parathyroidectomy (PTX) is often necessary despite medical treatment. However, the effect of PTX on cardio- and cerebrovascular events (CVE) remains...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05020-z
更新日期:2019-08-01 00:00:00
abstract:BACKGROUND:A substantial number of people are suffering from gastroesophageal reflux disease (GERD). The indication for surgical treatment is the failure of medical treatment in patients with objectively verified GERD. The use of PPIs has been noted to increase with the length of follow-up after fundoplication, raising...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3924-8
更新日期:2017-08-01 00:00:00
abstract::This study assessed the results of surgical treatment for Graves' disease in our hospital and examined the relationship between the values of thyroid stimulating hormone (TSH) receptor antibodies and postoperative thyroid function. From 1983 to 1988, subtotal thyroidectomy was performed in 313 patients with Graves' di...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF02067345
更新日期:1992-07-01 00:00:00
abstract:BACKGROUND:Frailty is a customized marker of biological age that helps to gauge an individual's functional physiologic reserve and ability to react to stress and is associated with increased postoperative morbidity and mortality. In order to mitigate frailty preoperatively, the concept of prehabilitation has entered th...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-020-05658-0
更新日期:2020-11-01 00:00:00
abstract::Mass screening for the purpose of detecting thyroid cancer at its earliest stage may not be recommended at the present time, but screening focused on certain risk groups is advocated. Familial nonmedullary thyroid carcinoma (FNMTC) is a distinct clinical entity with a high incidence of multifocality and association wi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7676-x
更新日期:2004-11-01 00:00:00
abstract::Cancers of the distal rectum (less than 7.5 cm from the anal verge) that are freely mobile, moderately well or well differentiated, less than 4 cm in size, limited to the bowel wall, and without evidence of metastasis should be considered candidates for treatment with electrocoagulation for cure. Tumor cell ploidy and...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF02104447
更新日期:1992-05-01 00:00:00
abstract:BACKGROUND:Surgical resection remains the treatment of choice for carotid body tumors (CBTs). Although perioperative complications such as carotid artery injury and neurological deficits occur infrequently, they can be devastating. The aim of this study was to evaluate whether clinical factors or preoperative imaging f...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3058-9
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Early mortality in ruptured abdominal aneurysm (rAAA) is high, but data on long-term outcome are scarce. The aim of this study was to investigate the long-term outcome in survivors after open surgery for rAAA in well-defined population. METHODS:This is a population-based, observational long-term follow-up (...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05457-7
更新日期:2020-06-01 00:00:00
abstract:INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-015-3386-9
更新日期:2016-05-01 00:00:00
abstract::Most of the work of host defense has been carried out in mixed patient populations. It is now clear that elective preoperative surgical patients have totally different host defense capabilities as compared to posttrauma patients or those suffering from peritonitis. Specific cell-mediated immune studies need to be repe...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01664871
更新日期:1990-03-01 00:00:00
abstract:BACKGROUND:Reported results of incisional hernia repair are poor with high recurrence rates unless prosthetic mesh is used. Mesh gives improved results, but certain techniques are associated with a high incidence of infections, fistulas, and seromas. This study reports the results of a consecutive series of incisional ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9118-z
更新日期:2008-01-01 00:00:00
abstract::Telomerase adds hexameric repeats of 5'-TTAGGG-3' to the ends of chromosomal DNA (telomere) and has been implicated in cell immortalization and cellular senescence. The aim of this study was to measure quantitatively the telomerase activity and human telomerase RNA component (hTR) content in gastric cancer and to exam...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010246
更新日期:2000-10-01 00:00:00
abstract::Idiopathic portal hypertension (IPH) requires invasive measures to prevent rupture and bleeding of esophagogastric varices. However, the long-term results of shunt surgery for IPH have not been reported. In particular, the pros and cons of surgery that preserves the spleen and its long-term hematologic effects have no...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-7656-9
更新日期:2005-08-01 00:00:00
abstract:BACKGROUND:The recent development and spread of ultrasonography and ultrasonography-guided fine needle aspiration biopsy (FNAB) has facilitated the detection of small papillary microcarcinomas of the thyroid measuring 1 cm or less (PMC). The marked difference in prevalence between clinical thyroid carcinoma and PMC det...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0303-0
更新日期:2010-01-01 00:00:00
abstract:BACKGROUND:The aim of the present study was to evaluate the influence of donor age on liver regeneration and surgical outcomes in recipients and donors. PATIENTS AND METHODS:Among 101 cases of adult-to-adult living donor liver transplantation (LDLT) between March 2002 and March 2011, according to donor age: younger (Y...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1496-1
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:In the past decade, Enhanced Recovery after Surgery (ERAS) protocols have been implemented in several fields of surgery. With these protocols, a faster recovery and shorter hospital stay can be accomplished without an increase in morbidity or mortality. The purpose of this study was to review systematically ...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-013-2044-3
更新日期:2013-08-01 00:00:00
abstract:BACKGROUND:The aims of this study were to investigate predictive factors for microscopic portal venous invasion (mPVI) in hepatocellular carcinoma (HCC) and whether anatomical liver resection (ALR) was useful in such cases. METHODS:We analyzed 852 patients with HCC without macroscopic portal venous invasion who were t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3964-0
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Human factors research has suggested benefits of consistent teams yet no surgical team consistency measures have been established for teamwork improvement initiatives. METHODS:Retrospective analysis was conducted of teams performing consecutive elective procedures of unilateral primary total knee and hip re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2866-7
更新日期:2015-04-01 00:00:00
abstract::Pancreatic endocrine tumors (PETs) may be sporadic or inherited in the multiple endocrine neoplasia type 1 (MEN-1) syndrome. The inherited form is caused by mutations of the MEN-1 gene, which functions as a tumor suppressor gene and maps to chromosome 11q13. These tumors tend to have a better prognosis than their spor...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-4062-4
更新日期:2002-07-01 00:00:00
abstract::The surgical treatment of 30 cases of vascular thoracic outlet syndrome (TOS) in 25 patients is presented. Patients included 17 women and 8 men with average age of 26.1 years. The causes of compression were cervical rib ( n = 16), soft tissue anomalies ( n = 12), and scar tissue after clavicle fracture ( n = 2). Ten s...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-6808-z
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:The present study evaluated outcomes of patients undergoing proximal diversion using either a loop ileostomy or loop colostomy following distal colorectal resection for malignant and non-malignant disease. METHODS:A literature search of the Medline, Ovid, Embase and Cochrane databases was performed to ident...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-006-0218-y
更新日期:2007-05-01 00:00:00
abstract:BACKGROUND:Patients with stage II colorectal cancer (CRC) have a higher risk of recurrence when they have certain risk factors, including clinical and pathological patterns. However, as the prognostic role of molecular patterns for stage II disease is still unclear, this study aimed to investigate it. METHODS:A total ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05158-w
更新日期:2019-12-01 00:00:00
abstract::This retrospective study in 79 surgically treated patients with a proximal bile duct carcinoma revealed 12 patients with a median age of 59.5 years (range 21-73 years) who survived more than 5 years. These 12 patients were analyzed to identify specific patient characteristics for long-term survival. Fifteen patients d...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900571
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:Hepatic trisectionectomy is a challenge for surgeons. We describe a technique by combination of the Glisson pedicle method and anterior approach to perform hepatic trisectionectomy. METHODS:In this technique, the Glisson pedicles are isolated above the hilar plate without hilar dissection. After dividing th...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2579-y
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:Incidental gallbladder cancer (GBC) is frequently discovered on the specimen when cholecystectomy for a benign disease is performed. The objective of the present study was to assess the management of incidental GBC patients in a French registry. METHODS:Data on patients with GBC treated between 1998 and 200...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1134-3
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The importance of safe anesthesia for the best possible surgical outcomes in every patient is not disputed in high resource settings. Low-income countries lag far behind in the provision of, and training for, safe anesthesia practice. Too little is known about numbers and types of providers in a majority of ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2775-9
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:Intense disease surveillance and frequent lymph node metastases (LNMs) in papillary thyroid cancer (PTC) have resulted in increased locoregional recurrences. We examined the safety and efficacy of an optimized surgical approach including preoperative ultrasonography (US), bilateral thyroidectomy, routine com...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0307-9
更新日期:2010-06-01 00:00:00
abstract::Axillary dissection in patients with breast cancer is associated with significant morbidity. Because 85% of the patients with a cancer < or = 1 cm have negative axillary nodal status, axillary dissection in these patients is only a staging procedure. A study of the sentinel lymph node (SLN) biopsy has been developed t...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0272-4
更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Postoperative peritonitis (POP) following gastrointestinal surgery is associated with significant morbidity and mortality, with no clear management option proposed. The aim of this study was to report our surgical management of POP and identify pre- and perioperative risk factors for morbidity and mortality....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4687-6
更新日期:2018-11-01 00:00:00