Abstract：
BACKGROUND:Inflammation is integral to the pathogenesis of abdominal aortic aneurysm (AAA). This study examines preoperative biomarkers of systemic inflammation in patients undergoing open repair of intact and ruptured AAA. METHODS:One-hundred twelve patients were entered into a prospective observational study. Preoperative POSSUM physiology score, C-reactive protein (CRP), white blood count (WBC), platelet count, fibrinogen, and albumin were recorded and related to clinical variables using univariate analysis. RESULTS:Sixty-one patients with a ruptured AAA, 39 with an asymptomatic intact AAA, and 12 with an acutely symptomatic intact AAA underwent attempted repair. There were two inflammatory asymptomatic aneurysms and one inflammatory ruptured aneurysm. No patient had clinical evidence of coexistent inflammatory disease. Patients with a symptomatic intact AAA had a significantly greater level of CRP and fibrinogen, higher WBC, and lower serum albumin, than those with an asymptomatic intact AAA. Patients with a ruptured aneurysm had a significantly greater level of CRP, higher WBC, and lower serum albumin than those with an asymptomatic intact aneurysm. Patients with a symptomatic intact AAA had a significantly higher CRP level, but lower WBC, than those with a ruptured AAA. There was no difference in CRP level, WBC, or serum albumin between survivors and non-survivors of attempted repair of asymptomatic, symptomatic and ruptured AAA. CONCLUSIONS:Acutely symptomatic and ruptured AAAs are associated with an early elevation in systemic inflammatory biomarkers. This early activation of the inflammatory response might influence perioperative outcome.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Tambyraja AL,Dawson R,Valenti D,Murie JA,Chalmers RTdoi
10.1007/s00268-007-9014-6subject
Has Abstractpub_date
2007-06-01 00:00:00pages
1210-4issue
6eissn
0364-2313issn
1432-2323journal_volume
31pub_type
杂志文章abstract：:Surgical resection is the treatment of choice for patients with stage I and stage II non-small-cell lung cancer (NSCLC--squamous cell, adenocarcinoma, and large-cell carcinoma). Distant recurrence is an important cause of death after complete surgical resection, occurring in 30-60% of patients. Postoperative adjuvant ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01659083
更新日期：1993-11-01 00:00:00
abstract：:The present prospective clinical study was carried out to investigate the effect of age on mortality, morbidity, and readmission rates after coronary artery bypass grafting (CABG). Data on 1131 consecutive CABG patients were collected in a surgical center and in all 18 secondary referral hospitals up to 3 months after...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-003-7033-5
更新日期：2003-12-01 00:00:00
abstract：:This article attempts to put into a risk-related perspective modern red blood cell (RBC) transfusion therapy. When making the decision to transfuse, RBCs or blood products, it is important to weigh the risks and benefits of the proposed therapy. It is equally important to evaluate the risk of not transfusing and the m...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900181
更新日期：1996-11-01 00:00:00
abstract：:The lack of sufficient suitable human donor lungs for the many patients requiring pulmonary transplantation as life-saving therapy for end-stage lung diseases has generated extensive interest in cross-species lung transplantation. Ethical concerns and those of animal rights advocates have prompted studies of nonprimat...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900332
更新日期：1997-11-01 00:00:00
abstract：BACKGROUND:Although mortality after liver resection has declined, posthepatectomy liver failure (PHLF) remains a major cause of operative mortality. To date there is not consensus on a definition for PHLF. However, there have been many efforts to define PHLF causing operative mortality. In the present study we sought t...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-013-1959-z
更新日期：2013-05-01 00:00:00
abstract：:Hepatobiliary (HB) surgery is a challenging surgical subspecialty that requires highly specialized training and an adequate level of experience in order to be performed safely. As a result, minimally invasive HB surgery has been met with slower acceptance as compared to other subspecialties, with many surgeons in the ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-013-2276-2
更新日期：2013-12-01 00:00:00
abstract：BACKGROUND:Surgery for Graves' disease (GD) is usually performed after adequate control with medical treatment. Occasionally, rapid pre-operative optimization is required. The primary objective was to compare the outcomes of patients undergoing elective surgery for well-controlled GD with those undergoing rapid pre-ope...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-019-05125-5
更新日期：2019-12-01 00:00:00
abstract：:The objective of this study was to assess the validity and responsiveness of a new quality of life instrument, the Patient Generated Index (PGI), in patients with rectal cancer. Thirty-three patients with rectal cancer were administered the PGI, the European Organisation for Research and Treatment of Cancer (EORTC) Qu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-002-6360-2
更新日期：2002-11-01 00:00:00
abstract：:Calcium oxalate is a major component of renal stones, and its urinary concentration plays an important role in stone formation. Even a small increase in urinary oxalate has a significant impact on calcium oxalate saturation. Although primary hyperoxaluria is relatively uncommon, patients with calcium oxalate stones ha...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002680010193
更新日期：2000-10-01 00:00:00
abstract：BACKGROUND:Dickkopf-3 (DKK3) may act as a tumor suppressor as it is down-regulated in various types of cancer. This study assessed the DKK3 protein expression in gastric cancer and its potential value as a prognostic marker. METHODS:DKK3 expression was evaluated by immunohistochemistry in 158 gastric cancer samples fr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2886-3
更新日期：2015-04-01 00:00:00
abstract：:Fingertip injuries constitute a large portion of the traumatic injuries sustained to the hand and are frequently associated with significant disability for the patient. While many methods are available for the treatment of such injuries, quite often only certain procedures are appropriate for a particular digit in any...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01675641
更新日期：1991-07-01 00:00:00
abstract：:Uncontrolled bleeding from the cystic artery and its branches is a serious problem that may increase the risk of intraoperative lesions to vital vascular and biliary structures. On laparoscopic visualization anatomic relations are seen differently than during conventional surgery, so proper knowledge of the hepatobili...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/pl00012372
更新日期：1999-07-01 00:00:00
abstract：BACKGROUND:The survival impact of distal pancreatectomy (DP) with celiac axis resection for locally advanced pancreatic body/tail cancer remains unclear. METHODS:A total of 16 patients underwent DP with celiac axis resection, while 76 underwent standard DP for pancreatic body/tail cancer. The indications for DP with c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3670-3
更新日期：2017-01-01 00:00:00
abstract：:Malnutrition in its various forms is without doubt the commonest disease. Acute malnutrition resulting from a total lack of ingestion clearly shows that not only are water and electrolytes a priority for survival but also energy reserves. It also shows that the maximum wasting that the lean body mass can withstand is ...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/pl00012343
更新日期：1999-06-01 00:00:00
abstract：BACKGROUND:Schistosomiasis is a waterborne trematode with numerous subtypes affecting different areas of the body. Rob Ferreira Hospital is located in an endemic area for schistosomiasis in the Lowveld region of South Africa. We set out to determine the prevalence of Sch istosoma in appendicitis. METHODS:From 2009 to ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-015-2954-3
更新日期：2015-05-01 00:00:00
abstract：:Clinical, endoscopic, and laboratory data were collected prospectively in 701 patients with bleeding peptic ulcer. The overall rebleeding rate was 16.1% and increased the risk of a fatal outcome by 17 fold (1.2% versus 20.6%, p less than 0.001). Rebleeding was documented in more than 75% of the group who did not survi...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01664889
更新日期：1990-03-01 00:00:00
abstract：:Surgical oncology is one of the most frequently studied surgical specialties with regard to disparities in quality of care. There is variation in the care received according to nonclinical factors such as age, race and ethnicity, education, income, and even geographic region. Differences exist with regard to who gets ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9383-x
更新日期：2008-04-01 00:00:00
abstract：:The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Tw...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0291-1
更新日期：2002-06-01 00:00:00
abstract：:Despite a slow decline in the incidence of gastric cancer over the last 90 years, we can still expect to see over 100,000 patients die of this disease each decade in England and Wales. The 5-year survival rate has not improved during this century, which is largely due to the stage at diagnosis being unchanged. There a...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF00294709
更新日期：1995-07-01 00:00:00
abstract：:This retrospective study in 79 surgically treated patients with a proximal bile duct carcinoma revealed 12 patients with a median age of 59.5 years (range 21-73 years) who survived more than 5 years. These 12 patients were analyzed to identify specific patient characteristics for long-term survival. Fifteen patients d...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900571
更新日期：1999-01-01 00:00:00
abstract：BACKGROUND:Surgical disease burden falls disproportionately on individuals in low- and middle-income countries. These populations are also the least likely to have access to surgical care. Understanding the barriers to access in these populations is therefore necessary to meet the global surgical need. METHODS:Using g...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3765-x
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Splenic trauma is a common organ injury following blunt abdominal trauma. In order to establish the contemporary epidemiology of blunt splenic trauma in Scotland and to detect risk factors associated with patient outcomes, analysis of a multi-center database of trauma patients was performed. METHODS:The stu...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9218-9
更新日期：2007-11-01 00:00:00
abstract：:The hospital records of 639 patients affected by primary gastric cancer who were consecutively admitted to our unit during the period 1981-1995 were reviewed. Overall 220 underwent total gastrectomy (38 palliative), 12 had resection of the gastric stump, 195 had distal subtotal gastrectomy (55 palliative), 78 had bypa...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689910073
更新日期：2000-04-01 00:00:00
abstract：:This prospective study was instituted to assess whether the use of the on-pump method or the off-pump method affects changes in health-related quality of life (QOL) as evaluated a year after coronary artery bypass graft (CABG) surgery. Data including preoperative risk factors and postoperative morbidity up to discharg...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7486-1
更新日期：2004-10-01 00:00:00
abstract：BACKGROUND:Gallbladder (GB) cancer may be discovered incidentally by histopathologic examination following simple cholecystectomy. Incidental GB cancer > or =T2 or > or =N1 needs a second radical resection. It is a matter of concern whether the prognosis may be worse in patients with T2GB cancer who undergo a second ra...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0522-4
更新日期：2010-07-01 00:00:00
abstract：BACKGROUND:Seroma formation is a frequent postoperative complication following open ventral hernia repair (OVHR), especially in cases requiring wide subcutaneous dissection (WSD). The aim of this study was to evaluate the effectiveness of a new low-thrombin fibrin sealant for seroma prevention. METHODS:A total of 60 c...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-014-2691-z
更新日期：2014-11-01 00:00:00
abstract：:Evaluation of prognostic factors of adenocarcinoma of Vater's ampulla is still a matter of debate. The aim of this study was to evaluate retrospectively factors that influence early and long-term outcomes in a 20-year single-institution experience on ampullary carcinoma. A total of 94 consecutive patients with ampulla...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-004-7498-x
更新日期：2005-04-01 00:00:00
abstract：BACKGROUND:The recent development and spread of ultrasonography and ultrasonography-guided fine needle aspiration biopsy (FNAB) has facilitated the detection of small papillary microcarcinomas of the thyroid measuring 1 cm or less (PMC). The marked difference in prevalence between clinical thyroid carcinoma and PMC det...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0303-0
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND AND STUDY AIMS:Post-lobectomy bronchopleural fistula is a rare complication of lung resection surgery, and proper management is crucial for the successful resolution. Most published papers deal with surgical treatment. We report our experience with a new interventional management, endobronchial naso-bronchia...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3779-4
更新日期：2017-03-01 00:00:00
abstract：:A new technique for ligating vessels and similar structures that offers more security is described. The aim of the study was to test whether this hypothesis was correct. Six different types of knots, including the one described in this article were compared by a strength-testing study. The knots were tied on a silicon...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7675-6
更新日期：2005-10-01 00:00:00
