Abstract:
:The hospital records of 639 patients affected by primary gastric cancer who were consecutively admitted to our unit during the period 1981-1995 were reviewed. Overall 220 underwent total gastrectomy (38 palliative), 12 had resection of the gastric stump, 195 had distal subtotal gastrectomy (55 palliative), 78 had bypass procedures, 72 had explorative laparotomy, and 62 had no operation. Univariate and multivariate analyses were used to evaluate 5-year survival with respect to the main clinical, pathologic, and treatment variables after both curative and palliative treatments. Overall the 5-year survival after curative treatment (320 patients-operative mortality excluded) was 55.5%: 91.1% for stage IA, 71.5% IB, 62.4% II, 37.5% IIIA, 31.5% IIIB. Among patients who underwent palliative treatment 5-year survival was 13.1% after gastric resection (total or distal subtotal), 4.9% after the bypass procedures, 0 after explorative laparotomy, and 0 after no operation. Univariate and multivariate survival analyses showed that variables independently associated with poor survival were advanced stage, upper location and D1 lymphadenectomy after curative treatment, tumor spread to distant sites, and nonresectional surgery after palliative treatment. Multivariate analysis showed that even though survival with gastric cancer depends on predetermined factors, the type of surgery can have a significant effect on prognosis after both curative and palliative treatment.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Doglietto GB,Pacelli F,Caprino P,Sgadari A,Crucitti Fdoi
10.1007/s002689910073keywords:
subject
Has Abstractpub_date
2000-04-01 00:00:00pages
459-63; discussion 464issue
4eissn
0364-2313issn
1432-2323pii
10.1007/s002689910073journal_volume
24pub_type
杂志文章abstract::Frequently, several multiple abdominal reexplorations are needed in patients with acute necrotizing hemorrhagic pancreatitis (ANP) or with persistent intraabdominal sepsis (PIAS). Residual undrained necrotic and septic foci lead to multiple organ failure. To provide wide-open drainage of the abdominal cavity, since 19...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/BF01658968
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:Esophagectomy remains the standard treatment for resectable esophageal cancer, but the cure rate is low. Neoadjuvant therapy has been tried in attempts to prolong survival and reduce tumor recurrence. The aim of this study was to assess the surgical outcomes with and without neoadjuvant treatment for resecta...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-006-0016-6
更新日期:2006-12-01 00:00:00
abstract::Genital manifestations of lymphatic filariasis (genital LF) are a significant cause of disfigurement and disability in the developing world. Surgery is the standard treatment; however, definitive publications are lacking and best practice remains unclear. An exhaustive search strategy using keyword and subject heading...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-015-3220-4
更新日期:2015-12-01 00:00:00
abstract:BACKGROUND:Lymph node metastasis is important when evaluating the prognosis of patients with differentiated thyroid cancer (DTC). However, the current N-staging system cannot fully reflect the clinical significance of cervical lymph node metastasis in DTC. In this study, we employed Surveillance, Epidemiology, and End ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4343-6
更新日期:2018-06-01 00:00:00
abstract::The lack of sufficient suitable human donor lungs for the many patients requiring pulmonary transplantation as life-saving therapy for end-stage lung diseases has generated extensive interest in cross-species lung transplantation. Ethical concerns and those of animal rights advocates have prompted studies of nonprimat...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900332
更新日期:1997-11-01 00:00:00
abstract::This study compares the findings of conventional computed tomography (CT) and ultrasound (US) imaging in the preoperative evaluation of patients with abdominal aortic aneurysm (AAA). It also assesses the impact of preoperative CT-derived information on operative strategy. A prospective study was conducted of 96 patien...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900626
更新日期:1999-10-01 00:00:00
abstract:BACKGROUND:Although the low central venous pressure (LCVP) technique is used to decrease blood loss during liver resection, its efficacy and safety during transplant procedures are still debatable. Our study aimed to assess the effects of this technique and its clinical safety for recipients undergoing liver transplant...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-010-0544-y
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Measurement of the parathyroid hormone (PTH) level following total thyroidectomy (TTx) may allow prediction of postoperative hypocalcemia. We present an algorithmic method of managing hypocalcemia pre-emptively, based on the PTH level 1 h after operation. MATERIALS AND METHODS:We examined 423 consecutive pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0348-0
更新日期:2010-03-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to compare the short- and long-term outcomes of malnourished gastric cancer patients who underwent laparoscopic or open radical gastrectomy. BACKGROUND:Preoperative malnutrition is an independent risk factor for postoperative mortality and morbidity in major gastrointestinal surgery...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4138-9
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Insertion of a nasogastric tube (NGT) in an anesthetized, paralyzed, and intubated patient is difficult, and many methods have been proposed to aid in the procedure. We present a simple insertion technique. METHODS:A silicone NGT was made rigid by filling it with distilled water and freezing it. Patients we...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-009-0144-x
更新日期:2009-09-01 00:00:00
abstract::There has been a long, unresolved debate regarding the operation of choice for well differentiated carcinoma of the thyroid. We therefore analyzed the feasibility, scope, sample size, and length of follow-up required to determine the optimal operation for papillary thyroid carcinoma. A statistical approach was used to...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689900016
更新日期:1996-01-01 00:00:00
abstract:BACKGROUND:Trauma is the third leading cause of death worldwide after cardiovascular and oncologic diseases. Predominant causes of trauma-related death (TD) are severe traumatic brain injury (sTBI), hemorrhagic shock, and multiple organ failure. An analysis of TD is required in order to review the quality of trauma car...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05347-7
更新日期:2020-04-01 00:00:00
abstract:INTRODUCTION:Urogenital dysfunction is a well recognized complication of rectal cancer surgery. The aim of this study was to assess the impact of autonomic nerve preservation (ANP) and lateral node dissection (LND) on male urogenital function after total mesorectal excision for lower rectal cancer. METHODS:We studied,...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0050-9
更新日期:2006-06-01 00:00:00
abstract:BACKGROUND:Preoperative detection of vocal cord palsy is important in thyroid and parathyroid surgery. However, routine fiberoptic laryngoscopy may bring patients unnecessary discomfort. The aim of this study was to determine the feasibility of using surgeon-performed ultrasonography (US) as a screening tool for preope...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1674-1
更新日期:2012-10-01 00:00:00
abstract:BACKGROUND:This prospective, non-randomized, comparative study evaluated morbidity of chemotherapy administration via a totally implantable venous access device (TIVAD) versus peripheral intravenous access (PIVA), and satisfaction in breast cancer patients in a limited-resource setting. METHODS:Consecutive patients re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2378-x
更新日期:2014-05-01 00:00:00
abstract::The metabolic changes in cancer cachexia appear to be mediated by a complex network of proinflammatory cytokines, neuroendocrine hormones, neurotransmitters, eicosanoids, and tumor-derived factors produced by the body in response to the tumor and by the tumor itself. The relative importance of these various mediator p...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002689910110
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:The Mangled Extremity Severity Score (MESS) was constructed as an objective quantification criterion for limb trauma. A MESS of or greater than 7 was proposed as a cut-off point for primary limb amputation. Opinions concerning the predictive value of the MESS vary broadly in the literature. The aim of this s...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05263-w
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Artificial intelligence is touted as the future of medicine. Classical algorithms for the detection of common bile duct stones (CBD) have had poor clinical uptake due to low accuracy. This study explores the challenges of developing and implementing a machine-learning model for the prediction of CBD stones i...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05820-8
更新日期:2021-02-01 00:00:00
abstract::Of the 2790 patients with gastric carcinoma who underwent surgery between January 1978 and December 1993, there were 224 who underwent a D2 resection for cancer of the proximal third of the stomach. Survival in these patients was retrospectively analyzed with special reference to the survival benefit of pancreaticospl...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900283
更新日期:1997-07-01 00:00:00
abstract::The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Tw...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0291-1
更新日期:2002-06-01 00:00:00
abstract:INTRODUCTION:The impact of diabetes mellitus (DM) on outcomes in patients undergoing emergency laparotomy for adhesive small bowel obstruction (ASBO) remains unknown. METHODS:Low-risk (ASA class of I and II) patients requiring emergency operation for ASBO were identified using the ACS NSQIP database. Propensity score ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3338-4
更新日期:2016-04-01 00:00:00
abstract:BACKGROUND:Dickkopf-3 (DKK3) may act as a tumor suppressor as it is down-regulated in various types of cancer. This study assessed the DKK3 protein expression in gastric cancer and its potential value as a prognostic marker. METHODS:DKK3 expression was evaluated by immunohistochemistry in 158 gastric cancer samples fr...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2886-3
更新日期:2015-04-01 00:00:00
abstract::Clinical parameters alone have repeatedly been proven unreliable in assessing cardiopulmonary status, especially in hemodynamically unstable patients. To learn if we had a diagnostic problem in our hospital, we compared physician assessment of cardiac index (CI) and thoracic fluid content (TFC) to values obtained usin...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s00268-004-2073-z
更新日期:2005-01-01 00:00:00
abstract:BACKGROUND:Nipple-sparing mastectomy (NSM) has gained widespread popularity in recent years. Nonetheless, patient selection, technical consideration and oncological safety of its extension to breast cancer treatment remain uncertain. Few publications have reviewed the application of NSM in Asian populations. METHODS:W...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-4197-y
更新日期:2018-05-01 00:00:00
abstract::Those benign breast disorders that are amenable to improvement by aesthetic surgery are discussed from the points of view of indications, techniques, and results. ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01658430
更新日期:1989-11-01 00:00:00
abstract::The limited number of publications on repair of the foramen of Morgagni hernia concentrates mainly on the laparotomy approach. We present our experience with the transthoracic approach. Patients who were diagnosed as having a foramen of Morgagni hernia and were operated on via the transthoracic approach between Decemb...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0055-4
更新日期:2005-11-01 00:00:00
abstract::In a double-blind placebo-controlled study we investigated the effect of recombinant human erythropoietin (r-HuEPO), on the perioperative hemoglobin concentration and the use of blood transfusions in patients undergoing elective colorectal surgery with a preoperative hemoglobin level =8.5 mmol/L. Altogether 100 were...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002689900561
更新日期:1999-01-01 00:00:00
abstract:BACKGROUND:There are few established metrics to define surgical capacity in resource-limited settings. Previous work hypothesizes that the relative frequency of cesarean sections (CS) at a hospital, expressed as a proportion of total operative procedures (%CS), may serve as a proxy measure of surgical capacity. We atte...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-012-1629-6
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:This study is intended to ascertain if outcome of acute abdominal surgery among elderly patients with acute abdominal pain have improved. METHODS:Altogether 456 patients aged >65 years underwent emergency abdominal surgery between the years 2007 and 2009 in our hospital. After excluding emergency reoperatio...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3207-1
更新日期:2015-12-01 00:00:00
abstract::Some 25%-70% of sporadic medullary thyroid carcinomas (MTCs) are associated with somatic mutations within the RET proto-oncogene. In a significant number of MTCs, however, no such genetic variations can be detected, which implies alternative pathogenic molecular alterations. To assess altered RET mutation-specific gen...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7748-y
更新日期:2005-04-01 00:00:00