Abstract:
BACKGROUND:Organ shortage is the greatest challenge facing the field of organ transplantation today. Use of more organs of marginal quality has been advocated to address the shortage. METHOD:We examined the pattern of donation and organ use in the United States as shown in the Organ Procurement and Transplantation Network/United Network for Organ Sharing database of individuals who were consented for and progressed to organ donation between January 2001 and December 2010. RESULTS:There were 66,421 living donors and 73,359 deceased donors, including 67,583 (92.1%) identified as donation after brain death and 5,776 (7.9%) as donation after circulatory death (DCD). Comparing two periods, era 1 (01/2001-12/2005) and era 2 (01/2006-12/2010), the number of deceased donors increased by 20.3% from 33,300 to 40,059 while there was a trend for decreasing living donation. The DCD subgroup increased from 4.9 to 11.7% comparing the two eras. A significant increase in cardiovascular/cerebrovascular disease as a cause of death was also noted, from 38.1% in era 1 to 56.1% in era 2 (p<0.001), as was a corresponding decrease in the number of deaths due to head trauma (48.8 vs. 34.9%). The overall discard rate also increased from 13,411 (11.5%) in era 1 to 19,516 (13.7%) in era 2. This increase in discards was especially prominent in the DCD group [440 (20.9%) in era 1 vs. 2,089 (24.9%) in era 2]. CONCLUSIONS:We detect a significant change in pattern of organ donation and use in the last decade in the United States. The transplant community should consider every precaution to prevent the decay of organ quality and to improve the use of marginal organs.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Saidi RF,Markmann JF,Jabbour N,Li Y,Shah SA,Cosimi AB,Bozorgzadeh Adoi
10.1007/s00268-012-1748-0subject
Has Abstractpub_date
2012-12-01 00:00:00pages
2909-13issue
12eissn
0364-2313issn
1432-2323journal_volume
36pub_type
杂志文章abstract:BACKGROUND:Recently, diagnostic criteria for malnutrition have been proposed by the European Society for Clinical Nutrition and Metabolism (ESPEN). This study aimed to investigate the utility of the ESPEN malnutrition criteria as a predictor for major complications following hepatectomy and pancreatectomy. METHODS:Dat...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05767-w
更新日期:2021-01-01 00:00:00
abstract:INTRODUCTION:Rectus sheath hematoma is rare. It can present to physicians in many specialties, but invariably the surgeon is contacted regarding management. It is frequently difficult to diagnose, which can result in delay of treatment or unnecessary surgery. Its incidence is on the rise. METHODS:We present a series o...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-005-0702-9
更新日期:2006-11-01 00:00:00
abstract:BACKGROUND:The specific definition of central hepatectomy (CH) (i.e., resection of segments 4-5-8 ± 1) is not uniformly used, resulting in conflicting comparisons with the more commonly performed extended hepatectomy (EH). The study aimed to compare, using propensity score matching (PSM) analysis, the incidence of post...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3584-0
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Medullary thyroid carcinoma (MTC) originates from calcitonin-producing cells of the thyroid. In 2009, we published our first report on the biological characteristics and prognosis of 118 MTC patients. Herein, we enrolled a larger number of patients with longer follow-up periods to further study the biologica...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4738-z
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Incidental gallbladder cancer (GBC) is frequently discovered on the specimen when cholecystectomy for a benign disease is performed. The objective of the present study was to assess the management of incidental GBC patients in a French registry. METHODS:Data on patients with GBC treated between 1998 and 200...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1134-3
更新日期:2011-08-01 00:00:00
abstract::The clinicopathological characteristics relevant to prognosis after surgical treatment of intrahepatic cholangiocarcinoma (ICC) remain unclear. In this study, the clinicopathological features of 19 patients with mass-forming ICC, the most common form of the disease, were reviewed to analyze prognostic determinants. Tw...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0291-1
更新日期:2002-06-01 00:00:00
abstract:BACKGROUND:Chronic anal fissure (CAF) is a linear split of the anoderm. The minimally invasive management of CAF such as botulinum toxin (BT) injection is recommended. However, the exact efficient dose of BT, number of injections per session and the injection sites are still debatable. The aim of this analysis was to a...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-016-3693-9
更新日期:2016-12-01 00:00:00
abstract::Cardiovascular disease [atherosclerosis and subsequent myocardial infarction (MI)] has been associated with primary hyperparathyroidism. We aimed at studying cardiovascular events before and after surgery and mortality after surgery for primary hyperparathyroidism using a historical follow-up design. A total of 674 pa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6541-z
更新日期:2003-02-01 00:00:00
abstract::Dissemination of new surgical knowledge, skills, and techniques across the wide spectrum of practicing surgeons in the community is often difficult and slow. This is even more problematic in countries such as Canada, where geographic distances separate a large portion of community surgeons from the large teaching cent...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9076-5
更新日期:2007-08-01 00:00:00
abstract:BACKGROUND:Perioperative blood transfusion has been shown to be associated with poor outcome in various types of malignancy. However, the relationship between the amount of blood loss and specific types of cancer recurrence has not been documented. METHODS:We retrospectively examined the amount of intraoperative blood...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-9979-4
更新日期:2009-06-01 00:00:00
abstract:BACKGROUND:This study evaluated the impact of tumor regression grading (TRG) and other pathologic variates in a cohort of rectal carcinoma patients treated with neoadjuvant chemoradiotherapy (CRT). The value of a grading less than pCR for predicting survival is unknown. Tumor budding has not been systematically studied...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1409-8
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:The Severe Acute Respiratory Syndrome Coronavirus 2 pandemic has exposed surgeons to hazardous working conditions, imposing the need for personal protective equipment (PPE) use during surgery. The use of such equipment may affect their non-technical skills, augment fatigue, and affect performance. This study...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05648-2
更新日期:2020-09-01 00:00:00
abstract::The hospital records of 639 patients affected by primary gastric cancer who were consecutively admitted to our unit during the period 1981-1995 were reviewed. Overall 220 underwent total gastrectomy (38 palliative), 12 had resection of the gastric stump, 195 had distal subtotal gastrectomy (55 palliative), 78 had bypa...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689910073
更新日期:2000-04-01 00:00:00
abstract::Whether for hepatic trauma or transplantation, a surgeon's knowledge of hepatic anatomy commonly determines a patient's outcome. The first medically relevant anatomic studies of the liver emerged with the endeavors of Herophilus and Erasistratus between 310 and 280 bc. Yet it was not until after the development of ane...
journal_title:World journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1007/s002689900238
更新日期:1997-03-01 00:00:00
abstract:BACKGROUND:Awake tracheostomy (AT) is aimed at securing the airway of patients with upper airway obstruction when other means are not feasible or have failed. Reports on AT in the literature are scarce. The goal of this study was to review our experience with the indications, complications and outcome of AT. METHODS:A...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4578-x
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:The purposes of this study were to determine clinical presentations and surgical outcomes of perforated peptic ulcer (PPU), and to evaluate the accuracy of the Boey scoring system in predicting mortality and morbidity. METHODS:We carried out a retrospective study of patients undergoing emergency surgery for...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-008-9796-1
更新日期:2009-01-01 00:00:00
abstract:BACKGROUND:Laparoscopic incisional and ventral hernia repair (LIVHR) is an alternative approach to conventional open incisional and ventral hernia repair (OIVHR). A consensus on outcomes of LIVHR when compared with OIVHR has not been reached. METHODS:As the basis for the present study, we performed a systematic review...
journal_title:World journal of surgery
pub_type: 杂志文章,meta分析,评审
doi:10.1007/s00268-014-2578-z
更新日期:2014-09-01 00:00:00
abstract:BACKGROUND:The role of preoperative imaging and the usability of different imaging modalities is highly variable and controversial in reduction mammaplasty patients. Our study describes the imaging process in a single center in regard to modality selection, age and timing, and of the association between imaging and his...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-017-3920-z
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVE:Gastroesophageal reflux disease (GERD) symptoms are commonly reported in primary hyperparathyroidism (pHPT). Although a calcium-mediated cause-and-effect relationship has been suggested, it remains unknown if parathyroidectomy improves GERD symptoms. METHODS:Over a 22-month period, 1,175 (39%) of 3,000 conse...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2876-5
更新日期:2015-03-01 00:00:00
abstract:INTRODUCTION:Recently, more aggressive variants of so-called well-differentiated thyroid carcinomas have been identified such as the tall cell variant, columnar cell variant, diffuse sclerosing variant, insular carcinoma, and Hürthle cell (oncocytic, oxyphilic) carcinomas. METHODS:An evidence-based review was performe...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-006-0837-3
更新日期:2007-05-01 00:00:00
abstract::To illustrate how the high incidence of arrow wounds provided a major stimulus for the development of surgery until a century ago, we conducted a literature search. Our research shows that archaic peoples developed considerable surgical skill for extraction of arrows, including thoracotomy and trephination. A classica...
journal_title:World journal of surgery
pub_type: 历史文章,杂志文章
doi:10.1007/s00268-001-0168-3
更新日期:2001-12-01 00:00:00
abstract::The role of nitric oxide in mediating smooth muscle relaxation is well established. Less is known about the downstream signaling events inside the smooth muscle cell that produce relaxation of the contractile machinery. One possible effector molecule is the small heat shock protein HSP20. Increased phosphorylation of ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-002-4052-6
更新日期:2002-07-01 00:00:00
abstract::Endocrine surgeons have had an important role in the management of hyperthyroidism due to either Graves' disease or toxic nodule(s). Since alternative treatments such as antithyroid drugs or radioiodine are also available, the decision-making for management should be based on clear assessment of advantages and limitat...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s002680010167
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Unilateral vocal fold paralysis (UVFP) may present as an uncommon complication of extralaryngeal neoplasms, requiring diagnostic scrutiny to seek occult tumors or diseases. The aim of this study was to examine the utility of computed tomography (CT) in evaluating adult UVFP of unknown etiology. METHODS:From...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-1991-z
更新日期:2013-06-01 00:00:00
abstract:BACKGROUND:The most important problem in pancreatic fistula is whether one can distinguish clinical pancreatic fistula, grade B + C fistula by the International Study Group on Pancreatic Fistula (ISGPF), from transient pancreatic fistula (grade A), in the early period after pancreaticoduodenectomy (PD). It remains uncl...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-009-0220-2
更新日期:2009-12-01 00:00:00
abstract::Local recurrence in differentiated and medullary thyroid carcinoma develops frequently from metastatic infiltration of cervical lymph nodes. Despite an aggressive surgical approach, postoperative calcitonin levels as biochemical evidence for residual cancer cells remain often elevated in patients with medullary thyroi...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0197-y
更新日期:2002-02-01 00:00:00
abstract::Hepatectomy with vascular reconstruction for biliary malignancy remains controversial. This study aimed to clarify the indications for surgery. Patients with advanced hilar bile duct cancer (HBDC) (n = 26) and gallbladder cancer (GBC) involving the hepatoduodenal ligament (n = 13) who underwent hepatectomy were enroll...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-6801-6
更新日期:2003-10-01 00:00:00
abstract::In a double-blind placebo-controlled study we investigated the effect of recombinant human erythropoietin (r-HuEPO), on the perioperative hemoglobin concentration and the use of blood transfusions in patients undergoing elective colorectal surgery with a preoperative hemoglobin level =8.5 mmol/L. Altogether 100 were...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/s002689900561
更新日期:1999-01-01 00:00:00
abstract::Inflammation is an essential component of the first phase of anastomotic wound healing, and it is suppressed by corticosteroids. The anti-inflammatory effect of corticosteroids is largely responsible for the impairment of wound healing in bowel anastomosis. It has been reported that local application of granulocyte-ma...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6505-3
更新日期:2002-10-01 00:00:00
abstract::The eponym "Graves' disease" is usually applied to the condition of immunogenic hyperthyroidism, in no small part due to the promotion and influence of the French physician Armand Trousseau who wrote in 1862, "Du Goître Exophthalmique, ou Maladie de Graves." However, the distinguished Bath physician Caleb Hillier Parr...
journal_title:World journal of surgery
pub_type: 传,历史文章,杂志文章
doi:10.1007/s00268-009-0297-7
更新日期:2010-06-01 00:00:00