Abstract:
:Knowledge of how factors related to esophageal cancer resection affect long-term quality of life after surgery is scarce, and no population-based studies are available. Therefore, we conducted a Swedish nationwide, prospective, population-based study of how esophageal surgery-related factors influence quality of life 6 months postoperatively. The Swedish Esophageal and Cardia Cancer register (SECC-register) encompasses 174 hospital departments (97%). Microscopically radically operated patients responded to a validated written questionnaire assessing quality of life. The basic questionnaire (QLQ-C30) and the esophagus-specific module (OES-24) were developed by the European Organization for Research and Treatment of Cancer. The Mann-Whitney test, the Jonckheere-Terpstras test, and logistic regression were used in statistical analyses. Among 100 included patients, the occurrence of surgery-related complications was the main predictor of reduced global quality of life 6 months after surgery (p for trend = 0.03). This effect remained after adjustment for potential confounding variables. Except for anastomotic strictures, each of the predefined complications--i.e., anastomotic leakage, infections, cardiopulmonary complications, and operative technical complications--contributed to decreased quality-of-life scores. Other potentially relevant factors--e.g. degree of lymph node dissection, resection margins, operative blood loss or duration, and hospital type--did not significantly affect quality of life. In conclusion, any measures that can reduce the risk of major surgery-related complications can decrease the negative impact on quality of life after esophageal cancer surgery. More population-based studies are warranted, however.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Viklund P,Lindblad M,Lagergren Jdoi
10.1007/s00268-005-7887-9keywords:
subject
Has Abstractpub_date
2005-07-01 00:00:00pages
841-8issue
7eissn
0364-2313issn
1432-2323journal_volume
29pub_type
杂志文章abstract::Endoscopic sphincterotomy (EST) is an established method for treatment of retained or recurrent common bile duct (CBD) calculi after cholecystectomy. Present experience shows that few patients have recurrent biliary tract complications, but follow-up periods are most often short. EST was performed in 147 patients with...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900043
更新日期:1996-03-01 00:00:00
abstract::Experience with screening for colorectal cancer has been disappointing. Prevention of this disease seems to be a more beneficial research direction. Although radical surgery presents the best treatment option, it is nonetheless an inadequate strategy by itself. A new dose intensive approach would temporally combine su...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01789207
更新日期:1991-09-01 00:00:00
abstract:PURPOSE:This study was designed to assess the chronological change in health-related quality of life (HRQOL) following robot-assisted distal gastrectomy (RADG) for early gastric cancer (EGC) and to compare the HRQOL of the patients undergoing RADG with that of the general population. METHODS:Patients undergoing RADG f...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2390-1
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Little is known of the oncological outcomes after adjuvant FOLFOX chemotherapy in patients with stage III colon cancer showing microsatellite instability high (MSI-H). In the present study we investigated the prognostic impact of MSI-H in patients with stage III colon cancer receiving FOLFOX chemotherapy. M...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-013-2120-8
更新日期:2013-10-01 00:00:00
abstract::During the three decades since the recognition of the Zollinger-Ellison syndrome (ZES), major progress has been made in the diagnosis and treatment of this disease. However, the many failed operations in patients with ZES, the existence of primary lymph node gastrinomas, and the surgical approach of patients with ZES ...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF01655107
更新日期:1993-07-01 00:00:00
abstract:BACKGROUND:This study aims to determine the prevalence and predictive factors for recurrence after sentinel lymph node biopsy (SLNB) and for sentinel lymph node positivity by SLNB in our population. METHODS:We followed up all SLNBs performed between 2002 and 2010 and analyzed data by R (version2.10.1), considering p <...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1420-0
更新日期:2012-04-01 00:00:00
abstract::The serum hyaluronate (HA) level reflects sinusoidal endothelial cell function correlated with liver function. We have reviewed multiple liver function indicators from 37 patients who underwent hepatectomy for various liver diseases. The serum HA level was well correlated with the indocyanine green retention rate at 1...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-004-7389-1
更新日期:2004-10-01 00:00:00
abstract::Studies have recorded significant patient discomfort during flexible sigmoidoscopy when it is performed without sedation/analgesia. This study observed whether a single dose of 50 mcg intravenous fentanyl reduces pain, improving compliance, acceptability, and completion rates. In a prospective study, 109 consecutive p...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s00268-004-7374-8
更新日期:2004-09-01 00:00:00
abstract:BACKGROUND:Acute appendicitis is the most common reason for abdominal surgery in young adults and children. Open appendectomy is still the treatment often chosen because it is simple, safe, and effective. Our aim was to study whether cosmetic results of appendectomy wounds are better after using continuous absorbable i...
journal_title:World journal of surgery
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00268-013-2396-8
更新日期:2014-05-01 00:00:00
abstract::A variety of techniques have been used for surgical treatment of hepatic hydatid cysts. The objective of this study is to describe the technique of diaphragm myoplasty, and to present our experience in the treatment of selected patients with hydatid disease of the liver by means of this alternative surgical technique....
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6558-3
更新日期:2003-02-01 00:00:00
abstract:BACKGROUND:The long-term course after peptic ulcer perforation is unclear, but because the ulcer population is generally older and has concomitant disease, the long-term prognosis may be expected to be poor. METHODS:In a study based on prospective data collection, all patients with peptic ulcer perforation treated at ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9370-2
更新日期:2008-03-01 00:00:00
abstract:BACKGROUND:The selection of the type of fundoplication or the necessity for an added fundoplication after esophagomyotomy (Heller's operation) for the treatment of achalasia remains controversial. The present retrospective study was designed to compare the long-term results of total and partial fundoplication on the my...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9385-8
更新日期:2008-03-01 00:00:00
abstract::Congenital short colon (CSC) is a condition in which the colon is replaced, wholly or partially, by a dilated pouch together with anorectal malformation and a colourinary fistula. Most of the reported series have been from northern India where this malformation is frequent. This paper details the management of 108 pat...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章
doi:10.1007/s002689900019
更新日期:1996-01-01 00:00:00
abstract::Eighty patients undergoing cholecystectomy were either assigned deliberately (n = 30) or randomized (n = 50) to drainage (n = 38) or nondrainage (n = 42). Subhepatic collections were seen on ultrasonography (US) after 48 to 72 hours in 12 of 35 patients with drainage and 24 of 42 patients without drainage (p < 0.05). ...
journal_title:World journal of surgery
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF01655718
更新日期:1993-01-01 00:00:00
abstract:BACKGROUND:Human factors research has suggested benefits of consistent teams yet no surgical team consistency measures have been established for teamwork improvement initiatives. METHODS:Retrospective analysis was conducted of teams performing consecutive elective procedures of unilateral primary total knee and hip re...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2866-7
更新日期:2015-04-01 00:00:00
abstract:INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
doi:10.1007/s00268-015-3386-9
更新日期:2016-05-01 00:00:00
abstract::To characterize hepatocellular carcinoma (HCC) cells with mutant (m) p53 protein histologically, we examined 68 main nodules and 20 accessory lesions of 72 patients with HCC who underwent hepatic resection between October 1990 and September 1993. Some sections were fixed in periodate-lysine-paraformaldehyde, embedded ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002689900033
更新日期:1996-02-01 00:00:00
abstract:BACKGROUND:Accurate presurgical assessment is important to anticipate postoperative complications, especially in the growing proportion of elderly cancer patients. We designed a study to define which comorbid conditions at the time of diagnosis predict complications after surgery for colorectal cancer. PATIENTS:A rand...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-005-0711-8
更新日期:2007-01-01 00:00:00
abstract:BACKGROUND:This study was intended to compare the prognostic power of the number of positive lymph nodes with that of the lymph node ratio in patients with ampullary carcinoma. METHODS:A retrospective analysis was conducted of the medical records of 71 consecutive patients with ampullary carcinoma who underwent pancre...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-011-1175-7
更新日期:2011-09-01 00:00:00
abstract:PURPOSE:There is no standardized treatment for patients with chemo-resistant or recurrent advanced ovarian cancer. Locoregional treatments combining cytoreductive surgery and intraperitoneal chemohyperthermia (HIPEC) may improve survival for locoregional disease. PATIENTS AND METHODS:A prospective single center study ...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-007-9146-8
更新日期:2007-09-01 00:00:00
abstract::The goals of operative treatment of primary hyperparathyroidism are (1) cure; (2) minimal invasion; and (3) cost-effectiveness. The optimal strategy is controversial. Retrospective review of was undertaken 66 previously unoperated patients having minimal-incision, full-neck exploration by one surgeon over 29 months. A...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s002680010238
更新日期:2000-11-01 00:00:00
abstract:BACKGROUND:Postoperative outcome prediction in elderly is based on preoperative physical status but its predictive value is uncertain. The goal was to evaluate the value of risk assessment performed perioperatively in predicting outcome in case of admission to an intensive care unit (ICU). METHODS:A total of 108 posts...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-020-05742-5
更新日期:2020-12-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-018-4679-6
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:Billions of people worldwide lack access to safe affordable surgery. Surgical missions and non-governmental organisations (NGO) are vital in meeting this need, but long-term outcomes are rarely reported. Mercy Ships is a surgical NGO, and we aimed to measure disability-free survival, impact and patient satis...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-016-3745-1
更新日期:2017-02-01 00:00:00
abstract:BACKGROUND:Utilization of breast reconstruction (BR) is low in many jurisdictions. We studied the geographical and surgical workforce factors that contribute to access and use of BR using a small area analysis approach with a geographical unit of analysis. METHODS:We linked administrative data from Ontario Canada to c...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-3060-2
更新日期:2015-08-01 00:00:00
abstract:BACKGROUND:Few guidelines exist for the initial management of wounds in disaster settings. As wounds sustained are often contaminated, there is a high risk of further complications from infection, both local and systemic. Healthcare workers with little to no surgical training often provide early wound care, and where r...
journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/s00268-014-2663-3
更新日期:2015-04-01 00:00:00
abstract:BACKGROUND:In 2002, the UICC/AJCC TNM classification for papillary thyroid carcinoma was revised. In this study, we examined the validity of this classification system by investigating the predictors of disease-free survival (DFS) and cause-specific survival (CSS) in patients. METHODS:We examined various clinicopathol...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-006-0455-0
更新日期:2007-04-01 00:00:00
abstract::This study was first designed to investigate systematically the kinetics of surface expression of scavenger receptors (SRs) and CD14 on alveolar macrophages in vivo and in vitro and their relation with local pro- and antiinflammatory responses in endotoxemia. The expression of SR and CD14 in lungs was down- and up-reg...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-002-6548-5
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Parathyroid cancer is rare. Differentiating parathyroid carcinoma from degenerative changes at histopathology can be difficult and studies investigating the value of single immunohistochemical markers have had variable results. In this study we aimed to investigate whether a panel of immunohistochemistry mar...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-014-2700-2
更新日期:2014-11-01 00:00:00
abstract::We retrospectively reviewed postoperative complications in 105 patients with hilar cholangiocarcinoma who underwent hepatectomy at Nagoya University Hospital from January 1990 through March 1999. Of the 105 subjects, 97 (92.4%) underwent resection of two or more Healey's segments of the liver. Combined portal vein res...
journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-001-0110-8
更新日期:2001-10-01 00:00:00