Abstract:
:The goals of operative treatment of primary hyperparathyroidism are (1) cure; (2) minimal invasion; and (3) cost-effectiveness. The optimal strategy is controversial. Retrospective review of was undertaken 66 previously unoperated patients having minimal-incision, full-neck exploration by one surgeon over 29 months. A group of 51 women and 15 men had open full neck exploration under general anesthesia through a small (25-40 mm) incision using specifically selected instruments; patients remained hospitalized overnight. Preoperative sestamibi scans were obtained before referral for 17 patients: 11 had localized disease, and 6 did not (65% sensitivity). Four parathyroid glands were identified in 98% of patients; intraoperative frozen section was used selectively on a median of one gland per patient. About 76% of patients had single-gland disease, 6% had two-gland disease, and 18% had four-gland hyperplasia. One patient had four normal cervical parathyroid glands and an aortopulmonary window parathyroid adenoma resected at thoracotomy 1 week later; preoperative sestamibi scans failed to localize his disease. There were no nerve injuries and a 98% cure rate after initial cervical exploration. Excluding the cost of the sestamibi scans, there was no difference between those who had preoperative localization and those who did not; 60% of hospital costs were operating room time-related. Minimal-incision parathyroidectomy is effective for curing hyperparathyroidism and has excellent cosmetic results with negligible scar. Preoperative sestamibi scanning had no impact on cure or treatment costs. Strategies to improve cost-effectiveness must address the substantial costs of anesthesia and operating room services.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Lowney JK,Weber B,Johnson S,Doherty GMdoi
10.1007/s002680010238keywords:
subject
Has Abstractpub_date
2000-11-01 00:00:00pages
1442-5issue
11eissn
0364-2313issn
1432-2323pii
10.1007/s002680010238journal_volume
24pub_type
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-003-7033-5
更新日期:2003-12-01 00:00:00
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journal_title:World journal of surgery
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journal_title:World journal of surgery
pub_type: 杂志文章
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2010-03-01 00:00:00
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更新日期:2015-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05177-7
更新日期:2020-02-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
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更新日期:2004-12-01 00:00:00
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pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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journal_title:World journal of surgery
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journal_title:World journal of surgery
pub_type: 杂志文章
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:1999-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-019-05208-3
更新日期:2020-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,评审
doi:10.1007/BF00316809
更新日期:1994-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2005-01-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
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更新日期:2010-07-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章
doi:10.1007/s00268-015-2958-z
更新日期:2015-05-01 00:00:00
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journal_title:World journal of surgery
pub_type: 杂志文章,多中心研究
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更新日期:2016-12-01 00:00:00