Abstract:
:Some pathogenesis-related genes are expressed in fungi only when the pathogen is in the host, but the host signals that trigger these gene expressions have not been identified. Virulent Nectria haematococca infects pea plants and requires either pelA, which is induced by pectin, or pelD, which is induced only in planta. However, the host signal(s) that trigger pelD expression was unknown. Here we report the isolation of the host signals and identify homoserine and asparagine, two free amino acids found in uniquely high levels in pea seedlings, as the pelD-inducing signals. N. haematococca has evolved a mechanism to sense the host tissue environment by using the high levels of two free amino acids in this plant, thereby triggering the expression of pelD to assist the pathogenic process.
journal_name
Proc Natl Acad Sci U S Aauthors
Yang Z,Rogers LM,Song Y,Guo W,Kolattukudy PEdoi
10.1073/pnas.0500312102keywords:
subject
Has Abstractpub_date
2005-03-15 00:00:00pages
4197-202issue
11eissn
0027-8424issn
1091-6490pii
0500312102journal_volume
102pub_type
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