Genetic analysis of 18 X-linked short tandem repeat markers in Korean population.

Abstract:

:The population genetic data of 18 X-chromosomal short tandem repeat (STR) markers DXS6807, DXS8378, DXS9895, DXS9902, DXS6810, DXS7132, DXS981, DXS6800, DXS9898, DXS6789, DXS101, DXS6797, GATA172D05, GATA165B12, HPRTB, GATA31E08, DXS8377, and DXS7423 were analyzed in samples of unrelated 220 males and 181 females from Korean population. The exact test for genotype distribution of the markers showed no significant deviation from the Hardy-Weinberg equilibrium. Allele frequencies between male and female samples were not significantly different in all examined markers. All examined males and females showed different hemizygotic haplotype and combined genotypes, respectively. Four cases of mutation were found in GATA172D05, GATA31E08, DXS7132, and HPRTB from the analysis of 95 father-child-mother trios. Details of X chromosomal STRs in Koreans would be useful in paternity tests and forensic purposes as well as whole X-chromosomal mapping studies.

journal_name

Forensic Sci Int

authors

Shin SH,Yu JS,Park SW,Min GS,Chung KW

doi

10.1016/j.forsciint.2004.04.012

keywords:

subject

Has Abstract

pub_date

2005-01-06 00:00:00

pages

35-41

issue

1

eissn

0379-0738

issn

1872-6283

pii

S0379073804002233

journal_volume

147

pub_type

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