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High performance liquid chromatographic determination of alcohols with reference to body distribution of methanol.

Abstract：

:A method has been developed on reverse phase high performance liquid chromatography for simultaneous determination of methyl, ethyl and isopropyl alcohols under refractive index detection using pure water as the mobile phase. A good separation has been achieved between these alcohols. Detector response was linear with a detection limit of 5 mg/100 ml. Recovery studies were performed by adding known amounts of methyl and ethyl alcohols to blood, lung and liver within the range 80-90%. The reproducibility of the results was always greater than 90%. The quantitative distribution of methyl alcohol in postmortem body tissues and fluids has been reported in three cases of poisoning.

journal_name

Forensic Sci Int

journal_title

Forensic science international

authors

Sharma VK,Jadhav RK,Rao GJ,Saraf AK,Chandra H

doi

10.1016/0379-0738(91)90156-d

subject

Has Abstract

pub_date

1991-09-01 00:00:00

pages

255-61

issue

2

eissn

0379-0738

issn

1872-6283

pii

0379-0738(91)90156-D

journal_volume

50

pub_type

杂志文章

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