Abstract:
:Previous studies have suggested that postmortem serum catecholamine levels reflect the magnitude of physical stress responses or toxic/hyperthermic neuronal dysfunction during the death process. The present study investigated postmortem adrenaline (Adr), noradrenaline (Nad), and dopamine (DA) levels in pericardial fluid (PCF) and cerebrospinal fluid (CSF) with regard to the cause of death, compared with right heart blood levels, in serial medicolegal autopsy cases with a postmortem time within 48 h (n=494). Correlations between PCF and CSF Adr levels, and those among right heart blood, PCF, and CSF DA levels were marked (r=0.66-0.83, p<0.0001), but were otherwise lower (r=0.22-0.44). With regard to the cause of death, Adr and Nad levels in PCF, CSF, and right heart blood mostly presented similar findings: these levels were generally high in injury, intoxication, and hyperthermia (heatstroke), but were low in hypothermia (cold exposure). DA levels at each site were higher in injury and intoxication. In addition, higher levels were detected for Nad levels in sharp instrument injury, as well as Adr, Nad, and DA in carbon monoxide intoxication at each site, and for CSF Nad in psychotropic drug intoxication. These findings suggest that characteristic elevations in Adr, Nad, and DA levels in PCF and CSF are involved in systemic responses to fatal stress and toxic neuronal dysfunction, reflecting the magnitude of such responses in individual cases.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Ishikawa T,Quan L,Michiue T,Kawamoto O,Wang Q,Chen JH,Zhu BL,Maeda Hdoi
10.1016/j.forsciint.2013.02.008subject
Has Abstractpub_date
2013-05-10 00:00:00pages
52-60issue
1-3eissn
0379-0738issn
1872-6283pii
S0379-0738(13)00073-Xjournal_volume
228pub_type
杂志文章abstract::Tooth formation is widely used to assess maturity and to predict age. Within clinical dentistry, such information aids in diagnosis and treatment planning. Numerous methods exist that allow either the prediction of age or an assessment of maturation. One widely used method was first described in 1973 by Demirjian et a...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.04.228
更新日期:2008-02-25 00:00:00
abstract:PURPOSE:The aim of this study is to investigate the value of whole body computed tomography (WB-CT) in bodies recovered from water by analysis of the imaging findings after drowning. METHODS:The bodies of 41 drowning victims and 9 persons who died from mechanical asphyxia by hanging underwent post-mortem whole body co...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2015.01.008
更新日期:2015-04-01 00:00:00
abstract::Retrospective analysis of 215 deaths in the bathtub (Institute of Forensic Medicine, University of Cologne, 1980-1993) revealed 12 fatalities involving children, seven boys and five girls, aged from 9 months to 13 years. The manner and cause of death was seven accidents (five by drowning, two by scalding burns), two n...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(95)98129-b
更新日期:1995-03-31 00:00:00
abstract::The amplification of the STR DYS391, using the primers described in the Genome Data Base (GDB: G00-365-251), shows not only an additional band to the Y-specific one in males with a size range of 26 bp less than those of DYS391 locus alleles, but also a polymorphic pattern in females in the same size range as the addit...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(00)00171-7
更新日期:2000-07-24 00:00:00
abstract::The population genetic data of 18 X-chromosomal short tandem repeat (STR) markers DXS6807, DXS8378, DXS9895, DXS9902, DXS6810, DXS7132, DXS981, DXS6800, DXS9898, DXS6789, DXS101, DXS6797, GATA172D05, GATA165B12, HPRTB, GATA31E08, DXS8377, and DXS7423 were analyzed in samples of unrelated 220 males and 181 females from...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.04.012
更新日期:2005-01-06 00:00:00
abstract::Most traditional techniques to recover latent fingermarks from metallic surfaces do not consider the metal surface properties and instead focus on the fingermark chemistry. The scanning Kelvin probe (SKP) technique is a non-contact, non-destructive method, used under ambient conditions, which can be utilised to recove...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.07.025
更新日期:2018-10-01 00:00:00
abstract::A number of biological and chemical tests have been developed over the years to determine whether a person was drowned. This study focuses on the potential of a microbiological test for detecting common bacterial markers of water faecal pollution such as faecal coliforms (FC) and faecal streptococci (FS) as possible i...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.09.004
更新日期:2008-11-20 00:00:00
abstract::Proton-induced X-ray emission (PIXE) is a spectroscopic technique that provides the researcher with the elemental composition of a given target material. In this paper, we illustrate the utility of PIXE analysis in two forensic contexts: (1) case of cremation in which the nature of the remains is questioned and (2) ca...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00614-4
更新日期:2002-01-24 00:00:00
abstract::Timing of fusion of the spheno-occipital synchondrosis (SOS) is correlated with age. Previous research, however, has demonstrated variation in the timing of closure among different global populations. The present study aims to quantify the timing of SOS fusion in Malaysian individuals as visualised in multi-detector c...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.12.046
更新日期:2018-03-01 00:00:00
abstract::Tooth wear is frequently used as a method of ageing skeletal remains. Fundamental to this method is the ability to measure the amount of tooth wear. The Brothwell chart based on the Miles method of ageing, uses simple ordinal scoring and is frequently used by archeologists. The purpose of the present investigation was...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(90)90110-k
更新日期:1990-12-01 00:00:00
abstract::In this study we demonstrate the use of Direct Analysis in Real Time Mass Spectrometry (DART) as a powerful tool for detection of nonoxynol in vaginal fluid post contact with a condom, enabling rapid tracing and added evidences in sexual assault crimes. Vaginal fluid was sampled using cotton swabs and glass rods and m...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.09.005
更新日期:2017-11-01 00:00:00
abstract::Many studies in the forensic field have reported that analysis of DNA methylation is the most reliable method of predicting age. In a previous study, 5 CpG sites located in ELOVL2, FHL2, KLF14, C1orf132 and TRIM59 genes were tested for age prediction purposes in blood, saliva and buccal swab samples from Korean indivi...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110267
更新日期:2020-06-01 00:00:00
abstract::A previously identified difficulty with the development of latent fingerprints on low-density polyethylene (LDPE) by vacuum metal deposition (VMD) is that excess gold deposition prevents effective zinc deposition and so inhibits latent print development [1]. The investigation of a means to correct for excess gold depo...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00507-2
更新日期:2001-11-15 00:00:00
abstract::Sudden infant death (SID) is an unresolved problem of high relevance and previous studies have indicated a role of viral heart infections. The diagnosis remains difficult in clinical practice using routine diagnostic tests and must be substantially improved. A prospective study based on post-mortem samples from SID vi...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.03.002
更新日期:2016-05-01 00:00:00
abstract::Two sewing needles were found in a woman's cranial cavity by X-ray examination after she had sustained traffic injury. After investigation and analysis, it has been confirmed that the sewing needles were inserted by others when she was an infant, and not by the traffic injury. ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00470-4
更新日期:2001-10-15 00:00:00
abstract::The aim of any forensic inquiry concerning accidental or criminal cremations is to identify the victims. This identification depends on an essential approach: a careful collection and ultrasonic cleaning of the fragments and splinters of burned bones, and reconstruction--as far as possible--of bone specimens, which im...
journal_title:Forensic science international
pub_type: 杂志文章,评审
doi:10.1016/s0379-0738(98)00115-7
更新日期:1998-09-28 00:00:00
abstract::A population study on 10 short tandem repeat (STR) loci was performed on 202 unrelated Czech Caucasians. DNA, initially frozen, was thawed and placed FTA paper. The DNA was purified in situ. DNA was amplified by PCR using the AmpFlSTR SGM Plus amplification kit. ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(00)00384-4
更新日期:2001-06-01 00:00:00
abstract::Chemical and physicochemical examinations of the fragments of an Egyptian mummy dated between the 3rd and 1st century B.C. were performed. The chemical examinations indicated the presence of resin in the skull and in the fragments of bandages wrapped around the mummy. An analysis of the infrared spectra of the fragmen...
journal_title:Forensic science international
pub_type: 历史文章,杂志文章
doi:10.1016/s0379-0738(98)00192-3
更新日期:1999-01-25 00:00:00
abstract::The aim of this study was to ascertain if a relationship between weapon choice and psychopathology existed. The perpetrators (103) were evaluated at the Department of Criminology and Forensic Psychiatry of the University of Bari in southern Italy. Psychiatric examination and psycho-diagnostic tests were administered f...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.01.019
更新日期:2011-06-15 00:00:00
abstract::Anabolic androgenic steroids (AAS) are the main class of doping agents and their consumption produces adverse effects involving several organs and systems. Three cases of sudden cardiac death (SCD) and one of death due to congestive heart failure of previously healthy athletes who were AAS users are herein reported. C...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.10.032
更新日期:2012-04-10 00:00:00
abstract::Synthetic cathinones constitute a major class of the new psychoactive substances (NPS) that have come to dominate recreational drug abuse in recent years. As synthetic cathinones are all chiral molecules, the use of chiral analysis to determine their enantiomeric ratios (ER) in seized drug samples can assist in the id...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110528
更新日期:2020-12-01 00:00:00
abstract::Eleven laboratories interested in the analysis of human hair for drugs of abuse participated in a study to determine how well drugs could be detected and quantified in hair. For the two exercises completed to date, substances to be determined were limited to cocaine, benzoylecgonine, and morphine. Samples sent to the ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(93)90283-g
更新日期:1993-12-01 00:00:00
abstract::A total of 48 methamphetamine hydrochloride samples from eight seizures were analyzed using gas chromatography-mass spectrometry (GC-MS) and gas chromatography with a flame ionization detector (GC-FID). Major impurities detected include 1,2-dimethyl-3-phenylaziridine, ephedrine/pseudoephedrine, 1,3-dimethyl-2-phenylna...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.09.012
更新日期:2008-11-20 00:00:00
abstract::Venlafaxine is a phenethylamine antidepressant which inhibits both serotonin and norepinephrine reuptake and is structurally unrelated to the serotonin reuptake inhibitors (SSRIs). Its major metabolite, O-desmethylvenlafaxine (ODV), also inhibits serotonin reuptake. Although metabolized by the cytochrome P-450 (CYP) s...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00455-8
更新日期:2001-09-15 00:00:00
abstract::Every year thousands of migrants die during the endeavour to reach the Italian coasts, making the Mediterranean the theatre of one of the greatest tragedies of mankind. Over 60% of these victims is buried unidentified: one of the reasons behind this is related to the specific difficulties and lack of strategies concer...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.01.029
更新日期:2018-04-01 00:00:00
abstract::In vitro evaluation of the effect of five insecticidal phosphoric and 11 thiophosphoric acid esters on different, non-specific human leukocytes esterases indicated that most of the organic phosphor compounds studied inhibited the activity of neutral alpha-naphthylacetate esterase, alpha-naphthylbutyryl esterase, and n...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(84)90192-0
更新日期:1984-07-01 00:00:00
abstract::When someone breaks glass a number of tiny fragments may be transferred to that person. If the glass is broken in the commission of a crime then these fragments may be used as evidence. A Bayesian interpretation of this evidence relies on, among other things, the forensic scientist's ability to assess the likelihood t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(97)00194-1
更新日期:1998-02-16 00:00:00
abstract::Changes related to chronological age are seen in both hard and soft tissue. A number of methods for age estimation have been proposed which can be classified in four categories, namely, clinical, radiological, histological and chemical analysis. In forensic odontology, age estimation based on tooth development is univ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.09.020
更新日期:2014-01-01 00:00:00
abstract::For crime scene investigation in cases of homicide, the pattern of bloodstains at the incident site is of critical importance. The morphology of the bloodstain pattern serves to determine the approximate blood source locations, the minimum number of blows and the positioning of the victim. In the present work, the ben...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.06.010
更新日期:2011-03-20 00:00:00
abstract::This research presents a new software, "Fragmento", for accurate analyses of fragmentary human skeletal remains and facilitation of three-dimensional (3D) fragmentary matching and full bone reconstruction. The framework utilizes the power of statistical bone atlases to create 3D templates for bone matching and to inte...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.03.017
更新日期:2017-06-01 00:00:00