Identification of impurities and statistical classification of methamphetamine hydrochloride drugs seized in China.

Abstract:

:A total of 48 methamphetamine hydrochloride samples from eight seizures were analyzed using gas chromatography-mass spectrometry (GC-MS) and gas chromatography with a flame ionization detector (GC-FID). Major impurities detected include 1,2-dimethyl-3-phenylaziridine, ephedrine/pseudoephedrine, 1,3-dimethyl-2-phenylnaphthalene, 1-benzyl-3-methylnaphthalene. These data are suggestive of ephedrine/pseudoephedrine as the main precursor of the methamphetamine hydrochloride samples seized during 2006-2007. Additionally the presence of 1,3-dimethyl-2-phenylnaphthalene, 1-benzyl-3-methylnaphthalene is indicative that six seizures were synthesized via the more specific ephedrine/hydriodic acid/red phosphorus method. In addition, five impurities were found for the first time in methamphetamine hydrochloride samples. Seventeen impurity peaks were selected from the GC-FID chromatograms. The peak areas of the selected peaks were then grouped for cluster analysis.

journal_name

Forensic Sci Int

authors

Zhang JX,Zhang DM,Han XG

doi

10.1016/j.forsciint.2008.09.012

subject

Has Abstract

pub_date

2008-11-20 00:00:00

pages

13-9

issue

1-3

eissn

0379-0738

issn

1872-6283

pii

S0379-0738(08)00366-6

journal_volume

182

pub_type

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