Abstract：
:Eleven laboratories interested in the analysis of human hair for drugs of abuse participated in a study to determine how well drugs could be detected and quantified in hair. For the two exercises completed to date, substances to be determined were limited to cocaine, benzoylecgonine, and morphine. Samples sent to the participating laboratories included hair from drug users, drug-free hair, and hair into which drugs had been soaked. For the first exercise, the hair samples were sent as powders; for the second, they were in the form of short segments. Results from these studies have shown that the laboratories, with a few exceptions, have performed very well qualitatively. However, scatter in quantitative results was high. Various approaches were used to liberate drugs from the hair, with the most commonly used, acid extractions and enzyme digestions, producing similar results. Laboratories using GC/MS generally performed well and reported no false positives. In contrast, one laboratory analyzing hair directly using MS/MS without extractions produced three of the four false positives and the worst quantitative results.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Welch MJ,Sniegoski LT,Allgood CCdoi
10.1016/0379-0738(93)90283-gsubject
Has Abstractpub_date
1993-12-01 00:00:00pages
295-303issue
1-3eissn
0379-0738issn
1872-6283pii
0379-0738(93)90283-Gjournal_volume
63pub_type
杂志文章abstract：:Driving while intoxicated (DWI) legislation requires proving the critical breath alcohol concentration (BrAC) at the time of driving. With time delayed analysis, retrograde extrapolation is occasionally employed but has several uncertainties associated with it. The present study attempts to address whether subjects ac...
journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/0379-0738(92)90013-m
更新日期：1992-12-01 00:00:00
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journal_title：Forensic science international
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1996-07-12 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1995-03-31 00:00:00
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journal_title：Forensic science international
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更新日期：2021-01-01 00:00:00
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journal_title：Forensic science international
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更新日期：2014-02-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2015-01-01 00:00:00
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更新日期：2020-03-01 00:00:00
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journal_title：Forensic science international
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更新日期：2012-05-10 00:00:00
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journal_title：Forensic science international
pub_type： 历史文章,杂志文章
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更新日期：2018-06-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2000-09-11 00:00:00
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journal_title：Forensic science international
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更新日期：2001-10-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：1996-11-11 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2015.03.006
更新日期：2015-05-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/s0379-0738(02)00372-9
更新日期：2002-12-04 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2010.10.017
更新日期：2011-05-20 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章,评审
doi：10.1016/s0379-0738(01)00645-4
更新日期：2002-02-18 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2006-04-20 00:00:00
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更新日期：1989-07-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2008-03-05 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2012-10-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2006.06.038
更新日期：2007-04-11 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2019-12-01 00:00:00
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journal_title：Forensic science international
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更新日期：2003-11-26 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2011.03.029
更新日期：2012-02-10 00:00:00
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journal_title：Forensic science international
pub_type： 杂志文章
doi：10.1016/j.forsciint.2009.12.055
更新日期：2010-04-15 00:00:00
abstract：:Gamma-hydroxybutyric acid's (GHB's) natural presence in the body has made the interpretation of its levels a challenging task for the forensic toxicologist. This study was designed to measure endogenous GHB levels in antemortem urine and blood samples. The range detected in urine was from 34 to 575 microg/dl and in bl...
journal_title：Forensic science international
pub_type： 杂志文章
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更新日期：2002-08-28 00:00:00
