Abstract:
:The study was performed to distinguish fatal from non-fatal blood concentrations of morphine. For this purpose, blood levels of free morphine and total morphine (free morphine plus morphine conjugates) in 207 cases of heroin-related deaths were compared to those in 27 drivers surviving opiate intoxication. The majority of both survivors and non-survivors were found to show a concomitant use of depressants including alcohol or stimulants. Blood morphine levels in both groups varied widely, with a large area of overlap between survivors (free morphine: 0-128 ng/ml, total morphine: 10-2,110 ng/ml) and non-survivors (free morphine: 0-2,800 ng/ml, total morphine: 33-5,000 ng/ml). Five (18.5%) survivors and 87 (42.0%) non-survivors exhibit intoxication only by morphine. In these cases, too, both groups overlapped (survivors-free morphine: 28-93 ng/ml, total morphine: 230-1,451 ng/ml; non-survivors-free morphine: 0-2,800 ng/ml, total morphine: 119-4,660 ng/ml). Although the blood levels of free or total morphine do not allow a reliable prediction of survival versus non-survival, the ratio of free/total morphine may be a criterion to distinguish lethal versus survived intoxication. The mean of the ratio of free to total morphine for all lethal cases (N=207) was 0.293, for those that survived (N=27) 0.135, in cases of intoxication only by morphine 0.250 (N=87) and 0.080 (N=5), respectively. Applying a cut-off of 0.12 for free/total morphine and performing ROC analyses, fatal outcome can be predicted in 80% of the cases correctly, whereas 16% of the survivors were classified as dead. Nevertheless, in this study, all cases with a blood concentration of 200 ng/ml and more of free morphine displayed a fatal outcome.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Meissner C,Recker S,Reiter A,Friedrich HJ,Oehmichen Mdoi
10.1016/s0379-0738(02)00343-2keywords:
subject
Has Abstractpub_date
2002-11-05 00:00:00pages
49-54issue
1eissn
0379-0738issn
1872-6283pii
S0379073802003432journal_volume
130pub_type
杂志文章abstract::A sample of 166 normal adult males and females was taken from different colleges of Assiut representing those living in upper Egypt. Each subject has been studied for measurements of stature (S), hand length (HL) and hand breadth (HB). The data were statistically analysed in order to assess the relationship between st...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(90)90304-h
更新日期:1990-07-01 00:00:00
abstract::We investigated the dynamic induction/expression of inducible nitric oxide synthase (iNOS) using human brains made available through death by traumatic brain injury (TBI). Astrocytes, microglia, and neutrophils were identified in tissue using immunohistochemical staining with antibodies against glial fibrillary acidic...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(01)00537-0
更新日期:2001-12-01 00:00:00
abstract::Determining the sequencing of intersecting ink lines is one of the current problems for forensic document examiners. The way two inks will distribute and interact with each other and the paper at the crossing is a dynamic process that can be affected by many variables. Thus, the main purpose of this manuscript is to v...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.10.026
更新日期:2014-01-01 00:00:00
abstract::Besides alcohol and drugs of abuse, several popular foods contain potentially toxic substances and cases of intoxication after consumption of these foods attract notice of forensic toxicology. This is also true for the case of a 34-year-old woman who was suspected to have suffered lethal acute intoxication from eating...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2009.12.018
更新日期:2010-04-15 00:00:00
abstract::Tooth formation is widely used to assess maturity and to predict age. Within clinical dentistry, such information aids in diagnosis and treatment planning. Numerous methods exist that allow either the prediction of age or an assessment of maturation. One widely used method was first described in 1973 by Demirjian et a...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.04.228
更新日期:2008-02-25 00:00:00
abstract::The assessment of sex is crucial to the establishment of a biological profile of an unidentified skeletal individual. The best methods currently available for the sexual diagnosis of human skeletal remains generally rely on the presence of well-preserved pelvic bones, which is not always the case. Postcranial elements...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2016.06.011
更新日期:2016-09-01 00:00:00
abstract::As part of a long-term project on Northeastern Brazilians, population genetic data were obtained from 323 unrelated individuals from the state of Paraíba. The loci studied were CSF1P0, TPOX, TH01, vWA, D16S539, D7S820, D13S317, D18S51, D21S11, D8S1179, F13A01, F13B and LPL. Their distributions are in Hardy-Weinberg eq...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.10.026
更新日期:2007-12-20 00:00:00
abstract::This is the first report in the forensic literature of a combination of fatal digoxin poisoning with endocardial fibroelastosis (EFE). Typical morphological features of EFE as the cause of clinically diagnosed cardiomyopathy were present in the autopsy of a 3-year-old girl, including cardiac hypertrophy and marked thi...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(97)00134-5
更新日期:1997-10-06 00:00:00
abstract::Several studies have shown variability in osteometric measurements of the skull between populations. Therefore, each population should have specific standards to optimize the accuracy of identification. The aim of this study was to evaluate the sexual dimorphism in metric relations between anatomical points of the sku...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.109916
更新日期:2019-09-01 00:00:00
abstract::Fingermarks that have insufficient characteristics for identification often have discernible characteristics that could form the basis for lesser degrees of correspondence or probability of occurrence within a population. Currently, those latent prints that experts judge to be insufficient for identification are not u...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110219
更新日期:2020-04-01 00:00:00
abstract::Identification of deceased persons is the most common role of the forensic dentist. Forensic physical comparison of antemortem and postmortem dental data is used to establish that a found body and a missing person are one and the same to a high degree of certainty. An overview of this role is presented as a review of ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.02.030
更新日期:2010-09-10 00:00:00
abstract::The allelic distribution of 15 short tandem repeat (STR) loci included in the AmpFl STR Identifiler kit was examined in 100 Changdu Tibetan and 118 Naqu Tibetan unrelated individuals living in the Tibet Province, PR China. The distribution of these observed genotypes was not significantly different from the expected d...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.03.012
更新日期:2007-07-04 00:00:00
abstract::GHB has been implicated in many cases of suspected surreptitious administration with the purpose of increasing victim vulnerability to sexual assault. Low amounts of endogenous (or naturally occurring) GHB, which do not reach pharmacologically active levels, have been detected in alcoholic and non-alcoholic beverages....
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.05.012
更新日期:2017-08-01 00:00:00
abstract::Blunt (non-penetrating) aortic injuries, in which the arterial wall is damaged in the direction from the intima towards the adventitia, are most commonly the result of a traffic accident. The various forms of blunt aortic injuries, from limited laceration of the intima to complete transection of the aorta, depend on t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2009.10.026
更新日期:2010-02-25 00:00:00
abstract::Hair, larvae and cardiac muscle, the only biological samples present on a skeletonized human body found in a rural area, were used for forensic toxicological analyses in order to determine possible causes of death. Since no information about the victim or the circumstances of death was available (except for the place ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.05.003
更新日期:2019-07-01 00:00:00
abstract::Since the anthrax mail attacks of 2001, law enforcement agencies have processed thousands of suspicious mail incidents globally, many of which are hoax bioterrorism threats. Bio-insecticide preparations containing Bacillus thuringiensis (Bt) spores have been involved in several such threats in Australia, leading to th...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.12.003
更新日期:2012-06-10 00:00:00
abstract::The aim of our study was to test the diagnostic value of iron (Fe) in fresh water drowning by investigating the postmortem levels of hemodilution in drowning cases compared to control cases. Twenty-six typical fresh water drowning cases were selected from 128 immersion cases autopsied in our Department of Forensic Pat...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.03.016
更新日期:2006-03-10 00:00:00
abstract::To improve the possibilities to delimitate the time of death after longer laytime, it was examined if this is possible by immunohistochemical insulin detection. The results show that in our examination material, the pancreatic beta-cells of up to 12-day-old corpses produce a positive immunoreaction towards insulin in ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(99)00124-3
更新日期:1999-11-08 00:00:00
abstract:BACKGROUND:Post-mortem Computed Tomography (PMCT) allows non-invasive or minimally invasive detection of findings that may or may not be visible during conventional autopsy, however, it does not allow the investigator to draw any conclusions regarding patency of the vessel's lumen. To address this deficiency, Post-mort...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110171
更新日期:2020-03-01 00:00:00
abstract::Research has been conducted to establish the effect that changes in relative humidity have on both the effectiveness of the cyanoacrylate fuming technique and the microstructures formed by the polymerisation reaction during the development of the marks. The study investigated 'natural' fingermarks and deliberately gro...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2011.06.003
更新日期:2011-10-10 00:00:00
abstract::Bloodstains often constitute the major physical evidence in crime investigation. Diluted blood invisible to the naked eye can be detected through presumptive tests however such tests can damage samples and prevent further processing such as DNA analysis. In this study, we compared the effects of luminol (prepared acco...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.06.017
更新日期:2011-03-20 00:00:00
abstract::The bodies of socially isolated people may remain undiscovered in their own houses for prolonged periods. Occasionally the body is in situ for sufficient time to become skeletonised, or partially so. Medico-legal investigation of these cases is complicated by degradation and contamination of evidence. Thus, a multidis...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.02.016
更新日期:2005-07-16 00:00:00
abstract:INTRODUCTION:3-methoxyphencyclidine (3-MeO-PCP) appeared on the illicit drug market in 2011 and is an analogue of phencyclidine, which exhibits anesthetic, analgesic and hallucinogenic properties. In this paper, we report data from a non-fatal intoxication and seven deaths involving 3-MeO-PCP in Sweden during the perio...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.02.034
更新日期:2017-06-01 00:00:00
abstract::The exposition to heavy metal-rich airborne due to fire practicing has forced to the development of heavy metal-free environmental ammunition primers all over the world. Here we characterize the GSR elements present in the Brazilian lead-free ammunition produced by Companhia Brasileira de Cartuchos (CBC) and commercia...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2007.07.005
更新日期:2008-05-02 00:00:00
abstract::Sex estimation is an integral aspect of biological anthropology. Correctly estimating sex is the first step to many subsequent analyses, such as estimating living stature or age-at-death. Klales et al. (2012) [6] provided a revised version of the Phenice (1969) [3] method that expanded the original three traits (ventr...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.05.001
更新日期:2017-08-01 00:00:00
abstract::Forensic material of alcoholics was compared with controls with regard to the height, weight, state of nutrition, stature, the ageing process and the presence of traumatic lesions. Surprisingly, it was found that alcoholic women were taller than controls. Alcoholics were significantly more often slightly undernourishe...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(94)01641-h
更新日期:1995-01-21 00:00:00
abstract::Forensic genetic genealogy, a technique leveraging new DNA capabilities and public genetic databases to identify suspects, raises specific considerations in a law enforcement context. Use of this technique requires consideration of its scientific and technical limitations, including the composition of current online d...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110543
更新日期:2020-11-01 00:00:00
abstract::A population study on the D1S80 locus in 100 northern Thais was performed using polymerase chain reaction (PCR) and high resolution polyacrylamide gel electrophoresis. Sixteen alleles and 39 genotypes were observed with a heterozygosity of 82%. In contrast to other studies, the allele with 31 repeat units was found to...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(96)01960-3
更新日期:1996-08-15 00:00:00
abstract::The FearID research project is aimed at the individualisation of earprints for the purpose of forensic research. The study presented here was carried out within the framework of this project. It intends to combine a review of what is known from literature on the classification and individualisation of earprints with r...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2003.10.024
更新日期:2004-02-10 00:00:00
abstract::A classification system is described for drugs using thin-layer chromatography (TLC), gas-liquid chromatography (GLC) and ultraviolet (UV) spectrophotometry. The TLC classifications are based on division of the plate into zones relative to a set of mixed drug standards. The GLC classification is based on Kovats' reten...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(79)90265-2
更新日期:1979-01-01 00:00:00