Delimitation of the time of death by immunohistochemical detection of insulin in pancreatic beta-cells.

Abstract:

:To improve the possibilities to delimitate the time of death after longer laytime, it was examined if this is possible by immunohistochemical insulin detection. The results show that in our examination material, the pancreatic beta-cells of up to 12-day-old corpses produce a positive immunoreaction towards insulin in all cases, whereas none of the corpses older than 30 days show such a reaction. This means that in case of a negative immunoreaction, the time of death can be assumed to lie more than 12 days before the autopsy. The fact that a negative immunoreaction occurs consistently after 30 days leads to the conclusion that when insulin has been stained in a specimen, the death of the respective person must lie a maximum of 29 days earlier, whereby these time-limits may change in considerably different surrounding conditions.

journal_name

Forensic Sci Int

authors

Wehner F,Wehner HD,Schieffer MC,Subke J

doi

10.1016/s0379-0738(99)00124-3

keywords:

subject

Has Abstract

pub_date

1999-11-08 00:00:00

pages

161-9

issue

3

eissn

0379-0738

issn

1872-6283

pii

S0379073899001243

journal_volume

105

pub_type

杂志文章
  • The use of photographs to record variation in bruising response in humans.

    abstract::There is considerable value in developing tools capable of accurately and reliably determining when bruises were inflicted in humans. Previous work has focused on the visual changes observed in a bruise as the injury develops and heals. However, due to variables such as how and where on the body the bruise was inflict...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2013.04.036

    authors: Lecomte MM,Holmes T,Kay DP,Simons JL,Vintiner SK

    更新日期:2013-09-10 00:00:00

  • Comparative analysis of condom lubricants on pre & post-coital vaginal swabs using AccuTOF-DART.

    abstract::In this study we demonstrate the use of Direct Analysis in Real Time Mass Spectrometry (DART) as a powerful tool for detection of nonoxynol in vaginal fluid post contact with a condom, enabling rapid tracing and added evidences in sexual assault crimes. Vaginal fluid was sampled using cotton swabs and glass rods and m...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2017.09.005

    authors: Proni G,Cohen P,Huggins LA,Nesnas N

    更新日期:2017-11-01 00:00:00

  • Application of a portable near infrared spectrometer for presumptive identification of psychoactive drugs.

    abstract::A portable near infrared spectrometer was applied to the presumptive identification of psychotropic drugs based on library searching. Data-treatment methods (mathematical pretreatment and library search algorithm) were examined on the basis of differentiation ability. The optimized mathematical pretreatment was a stan...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2014.05.020

    authors: Tsujikawa K,Yamamuro T,Kuwayama K,Kanamori T,Iwata YT,Miyamoto K,Kasuya F,Inoue H

    更新日期:2014-09-01 00:00:00

  • Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by headspace/solid phase micro-extraction (SPME) and GC/MS.

    abstract::The results of qualitative and quantitative analysis of some amphetamines and their analogs isolated from urine samples by solid phase micro-extraction with polydimethylsiloxane fibers are reported. The analytical method employed was gas-chromatography/mass spectrometry of head space samples. ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(96)02028-2

    authors: Centini F,Masti A,Barni Comparini I

    更新日期:1996-12-27 00:00:00

  • DNA methylation age estimation in blood samples of living and deceased individuals using a multiplex SNaPshot assay.

    abstract::Many studies in the forensic field have reported that analysis of DNA methylation is the most reliable method of predicting age. In a previous study, 5 CpG sites located in ELOVL2, FHL2, KLF14, C1orf132 and TRIM59 genes were tested for age prediction purposes in blood, saliva and buccal swab samples from Korean indivi...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2020.110267

    authors: Dias HC,Cordeiro C,Pereira J,Pinto C,Real FC,Cunha E,Manco L

    更新日期:2020-06-01 00:00:00

  • Toxicological analysis of cocaine adulterants in blood samples.

    abstract::Cocaine was the second most widely used drug in Europe in 2016, with 3.5 million consumers aged 15-64 years old. Adulterants are pharmacologically active substances developed for medical purposes, however, there is little knowledge about their influence in the human body when there is concomitant use with cocaine. The...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.03.005

    authors: Gameiro R,Costa S,Barroso M,Franco J,Fonseca S

    更新日期:2019-06-01 00:00:00

  • Incremental conditions of isolation as a predictor of suicide in prisoners.

    abstract::In a study of the incidence of suicide in jails and prisons under increasing conditions of deprivation in Italy from 2004 to 2008, imprisonment involving greater levels of isolation was found to be associated with a higher rate of suicide. Greater care should be taken to ensure that prisoners in isolation do not commi...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2013.08.016

    authors: Roma P,Pompili M,Lester D,Girardi P,Ferracuti S

    更新日期:2013-12-10 00:00:00

  • Generalized arterial calcification of infancy--Findings at post-mortem computed tomography and autopsy.

    abstract::Generalized arterial calcification in infancy is a rare genetic disorder characterized by abnormal calcification of large and medium sized arteries and marked myointimal proliferation resulting in arterial stenosis. The condition is often fatal secondary to complications of cardiac ischemia, hypertension and cardiac f...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.06.017

    authors: Bolster F,Ali Z,Southall P,Fowler D

    更新日期:2015-09-01 00:00:00

  • Preservation of dental evidence following exposure to high temperatures.

    abstract::The success of the Disaster Victim Identification (DVI) process relies upon sufficient post-mortem data being recovered to allow for a meaningful comparison with ante-mortem records of the missing person. Human bodies subjected to prolonged high temperatures, as experienced during the Black Saturday bushfires in Victo...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2010.08.011

    authors: Hill AJ,Lain R,Hewson I

    更新日期:2011-02-25 00:00:00

  • Workplace drug testing in Europe.

    abstract::Not much information is available on workplace drug testing (WDT) in Europe. There is no specific legislation and there are no generally accepted guidelines. Many companies establish a drug policy with little or no provisions for drug testing. Often, testing is performed on-site by occupational physicians, with little...

    journal_title:Forensic science international

    pub_type: 杂志文章,评审

    doi:10.1016/s0379-0738(01)00445-5

    authors: Verstraete AG,Pierce A

    更新日期:2001-09-15 00:00:00

  • A new 39-plex analysis method for SNPs including 15 blood group loci.

    abstract::A novel 39-plex typing system for single nucleotide polymorphisms (SNPs) has been developed. This multiplex approach has the advantage of being able to type 38 autosomal SNPs and one sex-discriminating base exchange site on the X and Y chromosomes rapidly and simultaneously. The SNP loci on the autosomes, which we exa...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2004.03.005

    authors: Inagaki S,Yamamoto Y,Doi Y,Takata T,Ishikawa T,Imabayashi K,Yoshitome K,Miyaishi S,Ishizu H

    更新日期:2004-08-11 00:00:00

  • Identification of human skin from a tissue fragment by detection of squamous cell carcinoma-related antigen using an enzyme immunoassay.

    abstract::A new method of identifying human skin from a tissue fragment by detection of squamous cell carcinoma-related (SCC) antigen, using an enzyme immunoassay, was developed. When an extract was prepared from 0.1 g human skin homogenized with 1 ml of phosphate buffered saline, this method was able to detect SCC antigen in e...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(96)02022-1

    authors: Kitao T,Miyaishi S,Yamamoto Y,Ishizu H

    更新日期:1996-12-02 00:00:00

  • Death in the "microwave oven": A form of execution by carbonization.

    abstract::Death in the "microwave oven" has nothing to do with microwaves energy. It is the jargon name given to a criminal form of execution by carbonization that has been adopted by drug dealers in Rio de Janeiro (Brazil). The goal is to torture and intimidate victims, in an attempt of corpse occultation and to make identific...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.05.012

    authors: Durão C,Machado MP,Daruge Júnior E

    更新日期:2015-08-01 00:00:00

  • Hyperplasia of islets of Langerhans and low serum insulin in cot deaths.

    abstract::Of the fifty-seven cases of cot death studied two-thirds were younger than 3 months, which is also the peak age of infantile hypoglycaemia. Findings from routine necropsy and histology were scarce; in eleven cases they could be regarded as potentially fatal. About half of the infants had had a mild virus-type infectio...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(80)90205-4

    authors: Hirvonen J,Jantti M,Syrjala H,Lautala P,Akerblom HK

    更新日期:1980-11-01 00:00:00

  • Postmortem distribution of guaifenesin concentrations reveals a lack of potential for redistribution.

    abstract::Therapeutic (or non-toxic) postmortem guaifenesin blood and liver concentrations have not been previously described. Peripheral blood guaifenesin concentrations were compared to central blood and liver concentrations in eight medical examiner cases. Specimens were initially screened for alcohol and simple volatiles, d...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2014.10.029

    authors: McIntyre IM,Navarrete A,Mena O

    更新日期:2014-12-01 00:00:00

  • Cyanide distribution in five fatal cyanide poisonings and the effect of storage conditions on cyanide concentration in tissue.

    abstract::The cyanide distribution in five fatal cyanide poisonings was analyzed by the pyridine-pyrazolone method using a Conway diffusion cell. In order to study the effect of storage conditions on cyanide concentration in tissue samples, the cyanide concentrations were first measured immediately after collection of the sampl...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(88)90164-8

    authors: Chikasue F,Yashiki M,Kojima T,Miyazaki T,Okamoto I,Ohtani M,Kodama K

    更新日期:1988-09-01 00:00:00

  • Ring positional differentiation of isomeric N-alkylated fluorocathinones by gas chromatography/tandem mass spectrometry.

    abstract::In analogy to our previously published procedure for the differentiation of regioisomeric fluoroamphetamines a method was developed, to differentiate ring positional isomeric fluorocathinones by product ion spectrometry of ions generated by chemical ionization (CI) under GC-MS conditions using methane as reagent gas. ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2012.08.011

    authors: Westphal F,Junge T

    更新日期:2012-11-30 00:00:00

  • Analysis of 418 cases of sexual assault.

    abstract::The aim of the study was to describe victim, assailant, assault characteristics for sexual assault victims according to the time between the last sexual assault and the examination, and to provide descriptive data on medico-legal findings. The study was based on 418 examined victims of sexual assault during the year 1...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/s0379-0738(02)00427-9

    authors: Grossin C,Sibille I,Lorin de la Grandmaison G,Banasr A,Brion F,Durigon M

    更新日期:2003-01-28 00:00:00

  • Chat Analysis Triage Tool: Differentiating contact-driven vs. fantasy-driven child sex offenders.

    abstract::Investigating crimes against children, specifically sexual solicitations, are complicated because not all offenders are contact-driven, meaning they want to meet the minor for sex in the physical world; instead, some offenders are fantasy-driven, in that they are more interested in cybersex and role-play. In addition,...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.02.028

    authors: Seigfried-Spellar KC,Rogers MK,Rayz JT,Yang SF,Misra K,Ringenberg T

    更新日期:2019-04-01 00:00:00

  • Children and guns: The detection of recent contact with firearms on children's hands by the PDT reagent.

    abstract::Throughout the world, young children are worryingly found to be involved in both unintentional and intentional gun violence, rendering the forensic investigation of gun handling by children a highly important matter. The effectiveness of the PDT reaction for mapping iron traces on hands of children has been tested and...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.05.008

    authors: Bar-Or KL,Almog J

    更新日期:2015-08-01 00:00:00

  • DNA and RNA extraction from low amount of blood volume.

    abstract::Clinical and research-based tests in molecular biology require a substantial amount of DNA and RNA, unfortunately, a considerable number of cells is needed for this amount of sample. Blood is one of the best and easiest source of cells, but is not used due to its invasive drawing methods and the needed volume. Another...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2019.109931

    authors: Farivar S,Ghazimoradi MH

    更新日期:2019-10-01 00:00:00

  • Differences in biomechanical properties and thickness among frontal and parietal bones in a Japanese sample.

    abstract::The aim of this study was to assess the mechanical properties and thickness of adult frontal and parietal bones. The heads of 114 Japanese cadavers (78 male cadavers and 36 female cadavers) of known age and sex were used. A total of 912 cranial samples, 8 from each skull, were collected. Samples were imaged using mult...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2015.04.029

    authors: Torimitsu S,Nishida Y,Takano T,Yajima D,Inokuchi G,Makino Y,Motomura A,Chiba F,Yamaguchi R,Hashimoto M,Hoshioka Y,Iwase H

    更新日期:2015-07-01 00:00:00

  • Superimposition and projective transformation of 3D object.

    abstract::Superimposition is an efficient method for evaluation of coincidence between a skull and a photo portrait. The principle of superimposition method lies in the projection of the skull into the face image. During the projection of an object with a perspective camera, the mapping of a three-dimensional object into a two-...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.06.062

    authors: Eliásová H,Krsek P

    更新日期:2007-04-11 00:00:00

  • Avian vitreous humor concentrations of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine as influenced by age and sex: their relevance as indicators of ante-mortem hypoxia.

    abstract::An investigation was made to determine the effects of age and sex on postmortem concentrations (mumol/l) of inosine, hypoxanthine, xanthine, uric acid, uracil and uridine in the vitreous humor of chickens (Gallus domesticus). Five male and 5 female chickens were sampled each week from 0-10 weeks of age. Samples were c...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(90)90206-e

    authors: Gardiner EE,Newberry RC,Keng JY

    更新日期:1990-09-01 00:00:00

  • Doping control analysis of selected peptide hormones using LC-MS(/MS).

    abstract::With the constantly increasing sensitivity and robustness of liquid chromatography-mass spectrometry-based instruments combined with enhanced reproducibility as well as mass accuracy and resolution, LC-MS(/MS) has become an integral part of sports drug testing programs particularly concerning the detection of peptide ...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2011.06.015

    authors: Thevis M,Thomas A,Schänzer W

    更新日期:2011-12-10 00:00:00

  • Differentiation between bruises and putrefactive discolorations of the skin by immunological analysis of glycophorin A.

    abstract::In a differential study to distinguish bruises from putrefactive discoloration, glycophorin A, a component of the erythrocyte membrane, was extracted from discolored skins and detected by immunological methods utilizing an anti-glycophorin A serum. Skin samples of 18 bruises, 8 postmortem hypostasises and 7 putrefacti...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/0379-0738(93)90219-z

    authors: Kibayashi K,Hamada K,Honjyo K,Tsunenari S

    更新日期:1993-10-01 00:00:00

  • Correlation of Delta9-tetrahydrocannabinol concentrations determined by LC-MS-MS in oral fluid and plasma from impaired drivers and evaluation of the on-site Dräger DrugTest.

    abstract::Oral fluid (collected with the Intercept((R)) device) and plasma samples were obtained from 139 individuals suspected of driving under the influence of drugs and analyzed for Delta(9)-tetrahydrocannabinol (THC), the major psychoactive constituent of cannabis, using a validated quantitative LC-MS-MS method. The first a...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2006.03.033

    authors: Laloup M,Del Mar Ramirez Fernandez M,Wood M,De Boeck G,Maes V,Samyn N

    更新日期:2006-09-12 00:00:00

  • Mitragynine concentrations in two fatalities.

    abstract::Two cases of fatalities are reported of which the recreational use of Mitragyna speciosa ("kratom") could be confirmed. One of these cases presents with one of the highest postmortem mitragynine concentrations published to date. Our results show that even extremely high mitragynine blood concentrations following the c...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2016.12.020

    authors: Domingo O,Roider G,Stöver A,Graw M,Musshoff F,Sachs H,Bicker W

    更新日期:2017-02-01 00:00:00

  • Predicting body movements for person identification under different walking conditions.

    abstract::Human motion during walking provides biometric information which can be utilized to quantify the similarity between two persons or identify a person. The purpose of this study was to develop a method for identifying a person using their walking motion when another walking motion under different conditions is given. Th...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2018.07.022

    authors: Nguyen DP,Phan CB,Koo S

    更新日期:2018-09-01 00:00:00

  • Transmesenteric hernia due to double-loop formation in the small intestine: a fatal case involving a toddler.

    abstract::We report a unique case of transmesenteric hernia resulting in death, which went undiagnosed during a recent hospital visit. The victim was a 2.5-year-old girl who - with the exception of chronic constipation - had no medical history. One night she complained of abdominal pains and was taken to a pediatric hospital wh...

    journal_title:Forensic science international

    pub_type: 杂志文章

    doi:10.1016/j.forsciint.2011.07.048

    authors: Kakimoto Y,Abiru H,Kotani H,Ozeki M,Tsuruyama T,Tamaki K

    更新日期:2012-01-10 00:00:00