Abstract:
:A portable near infrared spectrometer was applied to the presumptive identification of psychotropic drugs based on library searching. Data-treatment methods (mathematical pretreatment and library search algorithm) were examined on the basis of differentiation ability. The optimized mathematical pretreatment was a standard normal variate followed by the 2nd derivative. The correlation coefficient showed the best differentiation ability in the library search algorithms. Optimized data-treatment was effective for minimizing the effect of particle size on identification. The optimized data-treatment methods were validated by the spectra of psychotropic substances (n=120). Identification criteria for the psychotropic drugs were decided on the basis of the results of the validation. As a consequence, 8 out of 11 forensic samples containing psychoactive substances were able to be positively identified. Thus, the portable near infrared spectrometer with optimized data-treatment processing is a useful tool for rapid screening and presumptive identification of seized materials.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Tsujikawa K,Yamamuro T,Kuwayama K,Kanamori T,Iwata YT,Miyamoto K,Kasuya F,Inoue Hdoi
10.1016/j.forsciint.2014.05.020subject
Has Abstractpub_date
2014-09-01 00:00:00pages
162-171eissn
0379-0738issn
1872-6283pii
S0379-0738(14)00231-Xjournal_volume
242pub_type
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