Abstract:
:The increasing use of the potent hallucinogenic drug D-lysergic acid diethylamide (LSD) makes the application of highly sensitive analytical techniques necessary. For an effective analysis of biological specimens a limit of detection in the sub-ng/ml range is required. Using capillary electrophoresis (CE), with laser-induced fluorescence detection it was possible to determine 0.1-0.2 ng LSD/ml blood. The conventionally used immunoassays and gas and high-performance liquid chromatographic methods have cut-off values and limit of detection, respectively, in the same range. Only tandem mass spectrometry techniques can be more sensitive. Therefore, CE can be considered a good complementary method to conventional immunological and chromatographic techniques for the forensic analysis of biofluids.
journal_name
Forensic Sci Intjournal_title
Forensic science internationalauthors
Frost M,Köhler Hdoi
10.1016/s0379-0738(98)00017-6subject
Has Abstractpub_date
1998-04-05 00:00:00pages
213-8issue
2-3eissn
0379-0738issn
1872-6283pii
S0379-0738(98)00017-6journal_volume
92pub_type
杂志文章,评审abstract::This chapter employs the fracture assessment triad, a systematic analytical approach, as a vehicle to explore the components used to interpret gunshot trauma to the cranium. First, a list of pertinent observations associated with gunshot trauma to the cranium is presented with a brief description of each. These featur...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.05.019
更新日期:2019-08-01 00:00:00
abstract:PURPOSE:Changes in water diffusion can be quantified by diffusion-weighted MR imaging. However, there are only few reports about changes in post mortem brain. The aim of this study was to investigate the temporal pattern of the apparent diffusion coefficient (ADC) in the brain after death, to compare the values to in v...
journal_title:Forensic science international
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abstract::During a one-year-period 1243 medicolegal deaths in the City of Copenhagen were autopsied after the mode of death was provisionally determined by an external medicolegal examination. In 35% of the cases an atuopsy was requested by the police. Without autopsy the mode of death would have been defined erroneously in 10....
journal_title:Forensic science international
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abstract::3-Methylmethcathinone (3-MMC or metaphedrone) is a synthetic cathinone, recently introduced in the market of the new psychoactive substances (NPS), initially to replace mephedrone (4-methylmethcathinone or 4-MMC), and rapidly widespread among drug users. 3-Methylmethcathinone is legally controlled in many countries, b...
journal_title:Forensic science international
pub_type: 杂志文章,评审
doi:10.1016/j.forsciint.2018.11.024
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abstract::The study was performed to distinguish fatal from non-fatal blood concentrations of morphine. For this purpose, blood levels of free morphine and total morphine (free morphine plus morphine conjugates) in 207 cases of heroin-related deaths were compared to those in 27 drivers surviving opiate intoxication. The majorit...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(02)00343-2
更新日期:2002-11-05 00:00:00
abstract::The procedure used in this laboratory for removing and identifying contamination of hair specimens with drugs is demonstrated by its application to hair contaminated by various experimental models. The models include soaking; coating with drug followed by sweat conditions for 6 h; and soaking in a very high concentrat...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.04.024
更新日期:2004-10-29 00:00:00
abstract::Fingerprint Recognition System is widely deployed in variety of application domain, ranging from forensic to mobile phones. Its widespread deployment in various applications were person authentication are required, has caused concern that a leaked fingerprint template may be used to reconstruct the original fingerprin...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.04.045
更新日期:2018-07-01 00:00:00
abstract::To estimate age using DNA based on telomere shortening, we determined the terminal restriction fragment (TRF) length, as telomere length, using Southern blot analysis of peripheral human blood and blood stains. All blood stains had been stored at room temperature for 5 months. The average TRF length clearly showed a t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/s0379-0738(02)00086-5
更新日期:2002-05-23 00:00:00
abstract::A total of 48 methamphetamine hydrochloride samples from eight seizures were analyzed using gas chromatography-mass spectrometry (GC-MS) and gas chromatography with a flame ionization detector (GC-FID). Major impurities detected include 1,2-dimethyl-3-phenylaziridine, ephedrine/pseudoephedrine, 1,3-dimethyl-2-phenylna...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.09.012
更新日期:2008-11-20 00:00:00
abstract::Hypoglycemia was long considered to kill neurons by depriving them of glucose. We now know that hypoglycemia kills neurons actively from without, rather than by starvation from within. Hypoglycemia only causes neuronal death when the EEG becomes flat. This usually occurs after glucose levels have fallen below 1 mM (18...
journal_title:Forensic science international
pub_type: 杂志文章,评审
doi:10.1016/j.forsciint.2004.08.001
更新日期:2004-12-16 00:00:00
abstract::The identification of forensically important blowflies of the genus Chrysomya (Diptera: Calliphoridae) may be hampered by their close morphological similarities, especially as immatures. In contrast to most previous studies, the utility of a nuclear rather than mitochondrial genetic marker was investigated to solve th...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.01.009
更新日期:2008-05-20 00:00:00
abstract::Cadaver body bags are the conventional method to contain a human body or human remains, which includes the use for storage and transportation of the deceased at any crime scene or disaster scene. During disasters, most often than not, the first responders including the police will be equipped with cadaver body bags to...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2018.04.017
更新日期:2018-07-01 00:00:00
abstract:INTRODUCTION:Age assessment based on dental development is often requested in order to assess whether an individual is older or younger than 18 years of age. There are several statistical approaches to estimate age based upon third molar development. The aim of this study was to apply the principles of transition analy...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110145
更新日期:2020-03-01 00:00:00
abstract::DNA molecular techniques were used in a forensic investigation involving the poaching of wildlife in a national park of Italy. A poacher, after having snared a wild boar (Sus scrofa) sow, knifed it to death. The animal was retrieved by conservation officers at the scene before the poacher could remove the carcass. Sub...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2005.04.032
更新日期:2005-10-29 00:00:00
abstract::Allele frequencies and haplotype and haplogroup analysis have been performed for 16 Y-chromosome binary markers and 8 Y-chromosome STRs (DYS19, DYS385I and II, DYS389I and II, DYS390, DYS391, DYS392, DYS393). Data was obtained from a general sample of 93 unrelated individuals living in metropolitan areas from El Salva...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.07.005
更新日期:2007-09-13 00:00:00
abstract::This article studies teenage homicide victims in Metro-Dade County, Miami, FL, U.S.A., between the years 1973 through 1982. A total of 263 cases were selected. Cases were then analyzed with respect to age, race, sex, cause of death, scene circumstances, alcohol and drugs detected at autopsy. A discussion follows that ...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(84)90190-7
更新日期:1984-07-01 00:00:00
abstract::The dead body of a 44-year-old woman, previously known for depression and alcoholism, has been discovered at her place of residence by her husband. A forensic autopsy has been carried out. The results indicated unspecific histological lesions (alveolar oedema, liver steatosis and interstitial nephritis) but did not re...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2008.03.003
更新日期:2008-07-04 00:00:00
abstract::This paper presents a novel digital watermarking technique using face and demographic text data as multiple watermarks for verifying the chain of custody and protecting the integrity of a fingerprint image. The watermarks are embedded in selected texture regions of a fingerprint image using discrete wavelet transform....
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.08.019
更新日期:2007-07-04 00:00:00
abstract::Age estimation is a vital aspect in creating a biological profile and aids investigators by narrowing down potentially matching identities from the available pool. In addition to routine casework, in the present global political scenario, age estimation in living individuals is required in cases of refugees, asylum se...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2013.04.004
更新日期:2013-09-10 00:00:00
abstract::In the early eighties, in response to increasing self-poisoning incidents by pharmaceuticals in Singapore, a comprehensive wide-sweep screen for these drugs in clinical gastric aspirates was devised and implemented by us. The toxicological screen which involved quadruplicate extractions, two in acidic conditions and t...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(92)90158-s
更新日期:1992-05-01 00:00:00
abstract::An arson suspect's contact with an ignitable liquid container can leave small traces of the substance on his hands, but detecting these traces is difficult. This research paper presents a method to obtain clear gasoline detection even 3h after hands have been moistened with 50 μL of gasoline using activated charcoal s...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2010.07.031
更新日期:2011-03-20 00:00:00
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/0379-0738(94)01641-h
更新日期:1995-01-21 00:00:00
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journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2009.12.018
更新日期:2010-04-15 00:00:00
abstract::Due to inadequacies in historical hair examinations, the use and perceived value of microscopic hair evidence has reduced. Many reports have heavily criticised the use of pattern-based evidence including hair evidence as being unreliable, with police forces focussing on more individualising evidence. Hair evidence has...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110158
更新日期:2020-03-01 00:00:00
abstract::In developed countries, sudden infant death syndrome (SIDS) represents the most prevalent cause of death in children between 1 month and 1 year of age. SIDS is a diagnosis of exclusion, a negative autopsy which requires the absence of structural organ disease. Although investigators have confirmed that a significant p...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2012.01.018
更新日期:2012-06-10 00:00:00
abstract::In a study of subjects in drug rehabilitation programs, cocaine and cocaine metabolite levels were determined in the hair of 75 subjects who had produced cocaine-positive urine results. The hair was analyzed after being washed with the 3.75 h wash procedure developed by this laboratory. In addition, results of testing...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2004.04.033
更新日期:2004-10-29 00:00:00
abstract::Stabbings have been reported as the most frequent violent crime in countries where there is a severe restriction on obtaining firearms, such as the United Kingdom. Knives, scissors, and screwdrivers, as studied in this research, are among the most commonly encountered weapons involving stabbing events. When any of the...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2019.05.027
更新日期:2019-08-01 00:00:00
abstract::Protein-based medicines, or large molecule medicines, are innovative products used to treat various diseases like hepatitis or cancer. This new generation of molecules are usually expensive, and thus represents an attractive target for the counterfeiters. Due to the complexity of their chemical structure, their analys...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2017.07.012
更新日期:2017-09-01 00:00:00
abstract::CT-scanning as routine examination before medico-legal autopsy was introduced at the Institute of Forensic Medicine in Copenhagen, Denmark, in December 2002. The present series comprises of 525 medico-legal examinations performed in the year 2003. The purpose is to determine the value of CT-scanning prior to the post-...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2006.05.041
更新日期:2007-09-13 00:00:00
abstract::Fingermarks that have insufficient characteristics for identification often have discernible characteristics that could form the basis for lesser degrees of correspondence or probability of occurrence within a population. Currently, those latent prints that experts judge to be insufficient for identification are not u...
journal_title:Forensic science international
pub_type: 杂志文章
doi:10.1016/j.forsciint.2020.110219
更新日期:2020-04-01 00:00:00