Abstract：
AIM:To study the application of artificial neural network (ANN) in forecasting the incidence of hepatitis A, which had an autoregression phenomenon. METHODS:The data of the incidence of hepatitis A in Liaoning Province from 1981 to 2001 were obtained from Liaoning Disease Control and Prevention Center. We used the autoregressive integrated moving average (ARIMA) model of time series analysis to determine whether there was any autoregression phenomenon in the data. Then the data of the incidence were switched into [0,1] intervals as the network theoretical output. The data from 1981 to 1997 were used as the training and verifying sets and the data from 1998 to 2001 were made up into the test set. STATISTICA neural network (ST NN) was used to construct, train and simulate the artificial neural network. RESULTS:Twenty-four networks were tested and seven were retained. The best network we found had excellent performance, its regression ratio was 0.73, and its correlation was 0.69. There were 2 input variables in the network, one was AR(1), and the other was time. The number of units in hidden layer was 3. In ARIMA time series analysis results, the best model was first order autoregression without difference and smoothness. The total sum square error of the ANN model was 9 090.21, the sum square error of the training set and testing set was 8 377.52 and 712.69, respectively, they were all less than that of ARIMA model. The corresponding value of ARIMA was 12 291.79, 8 944.95 and 3 346.84, respectively. The correlation coefficient of nonlinear regression (R(NL)) of ANN was 0.71, while the R(NL) of ARIMA linear autoregression model was 0.66. CONCLUSION:ANN is superior to conventional methods in forecasting the incidence of hepatitis A which has an autoregression phenomenon.
journal_name
World J Gastroenteroljournal_title
World journal of gastroenterologyauthors
Guan P,Huang DS,Zhou BSdoi
10.3748/wjg.v10.i24.3579keywords:
subject
Has Abstractpub_date
2004-12-15 00:00:00pages
3579-82issue
24eissn
1007-9327issn
2219-2840journal_volume
10pub_type
杂志文章abstract：:Systemic therapy for hepatocellular carcinoma (HCC) has markedly advanced since the survival benefit of a molecular targeted agent, sorafenib, were demonstrated in the SHARP and Asia Pacific trials in 2007. Treatment options for patients with advanced HCC increased by sorafenib, and long-term survival for patients wit...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v25.i7.789
更新日期：2019-02-21 00:00:00
abstract：AIM:To describe a new clinical and pathological subtype of microscopic colitis in children. METHODS:A selected group of children with abdominal pain, constipation and/or diarrhoea showing discrete or no macroscopic abnormalities on endoscopy was described. RESULTS:Multiple biopsies of colon showed large mononuclear c...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.14.231
更新日期：2008-01-14 00:00:00
abstract：:Single-port laparoscopic surgery (SPLS) is proposed to be a step towards minimizing the invasiveness of surgery, and has since gained popularity in several surgical sub-specialties including hepatopancreatobiliary surgery. SPLS has since been applied to cholecystectomy, liver resection as well as pancreatectomy for a ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v20.i39.14329
更新日期：2014-10-21 00:00:00
abstract：:Currently approved treatments for hepatitis B virus (HBV) infection include the immunomodulatory agent, IFN-alpha, and nucleos(t)ide analogues. Their efficacy is limited by their side effects, as well as the induction of viral mutations that render them less potent. It is thus necessary to develop drugs that target ad...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v13.i6.830
更新日期：2007-02-14 00:00:00
abstract：AIM:To investigate the effect of Jianweiyuyang (JWYY) granule on gastric ulcer recurrence and its mechanism in the treatment of gastric ulcer in rats. METHODS:Gastric ulcer in rats was induced according to Okeba's method with minor modification and the recurrence model was induced by IL-1beta. The expression of vascul...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v11.i35.5480
更新日期：2005-09-21 00:00:00
abstract：AIM:to determine the effect of free serotonin concentrations in plasma on development of esophageal and gastric fundal varices. METHODS:this prospective study included 33 patients with liver cirrhosis and 24 healthy controls. Ultrasonography and measurement of serotonin concentration in plasma were carried out in both...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v16.i48.6135
更新日期：2010-12-28 00:00:00
abstract：AIM:To retrospectively evaluate the imaging features of pancreatic intraductal papillary mucinous neoplasms (IPMNs) in multi-detector row computed tomography (MDCT). METHODS:A total of 20 patients with pathologically-confirmed intraductal papillary mucinous neoplasms (IPMNs) were included in this study. Axial MDCT ima...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.15.4037
更新日期：2009-08-28 00:00:00
abstract：:We report a patient with HBV-related hepatocellular carcinoma (HCC) and refractory ascites who had received a peritoneal-venous shunt (PVS) 1 year before liver transplantation. Urgent surgical intervention following bowel obstruction and failure of immunosuppression therapy. No intestinal obstruction was found during ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v11.i34.5412
更新日期：2005-09-14 00:00:00
abstract：AIM:To determine the prevalences of symptoms consistent with gastroesophageal reflux disease (GERD) and dyspepsia in South America. METHODS:A telephone survey was conducted among adult owners of land-based telephones in São Paulo, Brazil, using previously validated computer-assisted sampling and survey protocols. The ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v20.i46.17388
更新日期：2014-12-14 00:00:00
abstract：:Although antagonists of tumor necrosis factor have resulted in major therapeutic benefits in inflammatory bowel disease, the magnitude and durability of response are variable. Similar to previously available drugs such as 5-aminosalicylates and immunomodulators, the therapeutic effect is not universal leaving many peo...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v20.i5.1139
更新日期：2014-02-07 00:00:00
abstract：:High-quality data remains scarce in terms of optimal management strategies in the elderly inflammatory bowel disease (IBD) population. Indeed, available trials have been mostly retrospective, of small sample size, likely owing to under-representation of such a population in the major randomized controlled trials. Howe...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v25.i30.4158
更新日期：2019-08-14 00:00:00
abstract：AIM:To clarify the benefit of surgical excision for patients with extrahepatic metastases of hepatocellular carcinoma (HCC). METHODS:We retrospectively reviewed the medical records of 140 patients with pathologically proven extrahepatic metastases of HCC and evaluated the outcomes of those who had undergone surgical r...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.15.5481
更新日期：2009-11-21 00:00:00
abstract：:Mesenchymal stromal cells (MSCs) are multipotent and self-renewing cells that reside essentially in the bone marrow as a non-hematopoietic cell population, but may also be isolated from the connective tissues of most organs. MSCs represent a heterogeneous population of adult, fibroblast-like cells characterized by the...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v20.i44.16418
更新日期：2014-11-28 00:00:00
abstract：AIM:To search the pathophysiological mechanism of diarrhea based on daily stool weights, fecal electrolytes, osmotic gap and pH. METHODS:Seventy-six patients were included: 51 with microscopic colitis (MC) (40 with lymphocytic colitis (LC); 11 with collagenous colitis (CC)); 7 with MC without diarrhea and 18 as a cont...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v11.i35.5535
更新日期：2005-09-21 00:00:00
abstract：:Study of the effects of natural products, including traditional Chinese Medicines, on acetaminophen hepatotoxicity has gained considerable popularity in recent years, and some of them showed positive results and even promising therapeutic potentials. A recent report suggested that Liuweiwuling tablets protect against ...
journal_title：World journal of gastroenterology
pub_type： 评论,信件
doi：10.3748/wjg.v22.i11.3302
更新日期：2016-03-21 00:00:00
abstract：AIM:To evaluate the effect of resveratrol, alone and in combination with fenofibrate, on fructose-induced metabolic genes abnormalities in rats. METHODS:Giving a fructose-enriched diet (FED) to rats for 12 wk was used as a model for inducing hepatic dyslipidemia and insulin resistance. Adult male albino rats (150-200 ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v22.i10.2931
更新日期：2016-03-14 00:00:00
abstract：AIM:To examine the effects of aspirin and enoxaparin on liver function, coagulation index and histopathology in a rat model of liver fibrosis. METHODS Forty-five male Sprague-Dawley rats were randomly divided into the control group (n = 5) and model group (n = 40). Thioacetamide (TAA) was used to induce liver fibrosis ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v23.i35.6412
更新日期：2017-09-21 00:00:00
abstract：AIM:To determine the possible existence of a hepato-cardiovascular response and its regulatory mechanism in normal rats. METHODS:Systemic hemodynamic changes following intraportal injection of latex microspheres were studied in two modified rat models of hepatic circulation, in which the extrahepatic splanchnic circul...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v11.i5.676
更新日期：2005-02-07 00:00:00
abstract：:INTRODUCTION:To intrestigate the relationship between tumor necrosis factor-alphaand liver fibrosis in patients with chronic liver disease.METHODS:Radioimmunoassay was made in 20 patients with mild chronic hepatitis(CMH),20 patients with severe chronic hepatitis(CSH),51 patients with liver cirrhosis(LC)and 32-normal p...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v4.i1.18
更新日期：1998-02-01 00:00:00
abstract：:Transforming growth factor-beta (TGF-beta), a prototype of multifunctional cytokine, is a key regulator of extracellular matrix (ECM) assembly and remodeling. Specifically, TGF-beta isoforms have the ability to induce the expression of ECM proteins in mesenchymal cells, and to stimulate the production of protease inhi...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v13.i22.3056
更新日期：2007-06-14 00:00:00
abstract：AIM:To investigate the effects of guggulsterone on the proliferation and apoptosis of human hepatoma HepG2 cells in vitro and relevant mechanisms. METHODS:Human hepatocellular carcinoma HepG2 cells and normal human liver L-02 cells were treated with different concentrations of guggulsterone (5-100 μmol/L) for 24-72 h....
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v21.i47.13277
更新日期：2015-12-21 00:00:00
abstract：:Liver cancers are the second most frequent cause of global cancer-related mortality of which 90% are attributable to hepatocellular carcinoma (HCC). Despite the advent of screening programmes for patients with known risk factors, a substantial number of patients are ineligible for curative surgery at presentation with...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v25.i32.4614
更新日期：2019-08-28 00:00:00
abstract：AIM:To investigate the association between interleukin-28B (IL28B) genotype and response to treatment and hepatic fibrosis in patients with hepatitis C virus (HCV) genotype 4. METHODS:Two hundred and one HCV-genotype 4 patients were included. All patients were treated with Peginterferon alph2a/Ribavirin for 48 wk. End...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v18.i47.7003
更新日期：2012-12-21 00:00:00
abstract：:A rare case of multiple small bowel ruptures due to ischemic enteritis (ISE) is reported. The patient was admitted to the hospital with acute abdominal pain followed by bloody diarrhoeas. Preoperative colonoscopic findings were similar to those presented in Crohn's disease. Intraoperatively, ischemic lesions and multi...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v12.i26.4262
更新日期：2006-07-14 00:00:00
abstract：:The yeast Saccharomyces boulardii CNCM I-745 is one of the probiotics recommended for the prevention of antibiotic-associated diarrhea. Studies conducted in vivo and in vitro demonstrated that in the case of infectious diseases there are two potential sites of action of Saccharomyces boulardii CNCM I-745: (1) An actio...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,评审
doi：10.3748/wjg.v25.i18.2188
更新日期：2019-05-14 00:00:00
abstract：AIM:To highlight magnetic resonance enterography (MRE) for diagnosis of patients with refractory iron deficiency anemia and normal endoscopy results. METHODS:Fifty-three patients diagnosed with iron deficiency anemia refractory to treatment and normal gastroscopy and colonoscopy results were admitted to this prospecti...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v20.i38.14004
更新日期：2014-10-14 00:00:00
abstract：AIM:To investigate the acute toxicity, phytochemical profile, antidiarrheal activity and mechanisms of action of Maytenus erythroxylon (M. erythroxylon) ethanol extract. METHODS:A castor oil-induced diarrhea model was used to evaluate antidiarrheal activity. Intestinal transit and gastric emptying protocols were used ...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v23.i24.4381
更新日期：2017-06-28 00:00:00
abstract：AIM:To investigate the role of pre-core and basal core promoter (BCP) mutations before and after hepatitis B e antigen (HBeAg) seroconversion. METHODS:The proportion of pre-core (G1896A) and basal core promoter (A1762T and G1764A) mutant viruses and serum levels of hepatitis B virus (HBV) DNA, hepatitis B surface anti...
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v21.i2.541
更新日期：2015-01-14 00:00:00
abstract：AIM:To explore a safe, efficient, and cost-effective technique for local thermo-ablation of hepatic tumors. METHODS:The livers of 16 healthy rabbits were thermocoagulated by diode-laser with a hand-made scanner fiber tip, 6 w for 10 min. At the same time, the temperature was measured at 5 and 10 mm from the laser tip....
journal_title：World journal of gastroenterology
pub_type： 杂志文章
doi：10.3748/wjg.v9.i10.2350
更新日期：2003-10-01 00:00:00
abstract：AIM:To compare biofeedback-guided pelvic floor exercise therapy (BFT) with the use of oral polyethylene glycol (PEG) for the treatment of obstructive defecation. METHODS:A total of 88 subjects were assigned to treatment with either BFT (n = 44) or oral PEG (n = 44). Constipation symptoms (including difficult evacuatio...
journal_title：World journal of gastroenterology
pub_type： 杂志文章,随机对照试验
doi：10.3748/wjg.v20.i27.9162
更新日期：2014-07-21 00:00:00
