Molecular detection of prostate cancer: a role for GSTP1 hypermethylation.

abstract：:Adenocarcinoma of the prostate is the most prevalent neoplastic disease in men and continues to be a major cause of morbidity and mortality. Death from prostate cancer is associated with objective and biochemical progression following hormonal manipulations often described as hormone refractory prostate cancer (HRPCA)...

journal_title：European urology

authors： Heidenreich A,von Knobloch R,Hofmann R

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the clinical impact of different definitions of hereditary prostate cancer (PCa), the relative risk (RR) of relatives of PCa cases and differences in clinical-pathological features and outcome as function of a family history in a surgical series exposed to Mediterranean diet. METHODS:We classifie...

journal_title：European urology

authors： Sacco E,Prayer-Galetti T,Pinto F,Ciaccia M,Fracalanza S,Betto G,Pagano F

更新日期：2005-06-01 00:00:00

abstract：:Primary non-Hodgkin's lymphoma of the bladder is a rare entity and when found in such an unusual location is often difficult to distinguish from other vesical or extravesical neoplasms. Understanding of the pathobiological characteristics of this malignancy has been hampered not only because of its rarity but also by ...

journal_title：European urology

authors： Melekos MD,Matsouka P,Fokaefs E,Pantazakos A,Repanti M

更新日期：1992-01-01 00:00:00

abstract：:The records of children enrolled in the National Wilms' Tumor Study-3 who had Wilms' tumor and thrombosis into the renal vein were reviewed. There were 164 patients with gross involvement of the extrarenal vein and 47 patients with microscopic involvement, an incidence of 11.3% (211 of 1,865 evaluable patients). Two-y...

journal_title：European urology

authors： Ritchey ML,Othersen HB Jr,de Lorimier AA,Kramer SA,Benson C,Kelalis PP

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Bone metastases (BMs) are frequently present in patients with metastatic renal cell carcinoma (mRCC) and cause significant morbidity. OBJECTIVE:The purpose of this analysis was to assess the impact of BMs and bisphosphonate therapy (BT) on outcomes in mRCC. DESIGN, SETTING, AND PARTICIPANTS:We conducted a ...

journal_title：European urology

authors： McKay RR,Lin X,Perkins JJ,Heng DY,Simantov R,Choueiri TK

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVES:Multifocality and frequent recurrence of urothelial carcinoma of the urinary bladder indicate a disease of the entire "urothelial field", but little is known about chromosomal alterations in histologically normal urothelium. Histopathologically normal urothelium from patients with and without concurrent urot...

journal_title：European urology

authors： Stoehr R,Zietz S,Burger M,Filbeck T,Denzinger S,Obermann EC,Hammerschmied C,Wieland WF,Knuechel R,Hartmann A

更新日期：2005-01-01 00:00:00

abstract：:The erythrocyte polyamines, spermidine and spermine, are known proliferation markers. The authors present their experience with polyamines and prostatic carcinoma. 229 patients with prostatic carcinoma had polyamine erythrocyte determination at diagnosis. Previous results confirmed a tendency to spermidine increase wi...

journal_title：European urology

authors： Cipolla B,Guillé F,Moulinoux JP,Quemener V,Staerman F,Corbel L,Lobel B

更新日期：1993-01-01 00:00:00

abstract：:23 medical faculties exist in Turkey at the moment and 2 others are being established. Considering that all these faculties run their own programs independently, different education systems might effect the standard of doctors and health care. All of the new graduates in this country face a centralized examination for...

journal_title：European urology

authors： Akdaş A,Simşek F,Ilker Y

更新日期：1990-01-01 00:00:00

abstract：:An experimental oedema of the bladder wall was produced by electric coagulation current in 130 rats. The amount of oedema was calculated by determination of the difference between the weight of the freshly excised wet bladder and that after drying to constant weight. Thus, oedema of a fairly constant and reproducible ...

journal_title：European urology

authors： Strohmenger P,Wenzel H

更新日期：1976-01-01 00:00:00

abstract：:Antitumor effect of recombinant human tumor necrosis factor alpha (TNF) alone or in combination with various anticancer chemotherapeutic agents was tested using an in vitro antiproliferative assay on four human renal carcinoma cell lines (VMRC-RCW, VMRC-RCZ, Caki-1 and A-498). When the dose-dependent effect of TNF was...

journal_title：European urology

authors： Ikemoto S,Hayahara N,Wada S,Nishio S,Maekawa M

更新日期：1991-01-01 00:00:00

abstract：:This case study reports one case of transvaginal natural orifice transluminal endoscopic surgery (NOTES) in a 23-yr-old woman with right flank pain and recurrent urinary tract infection due to a nonfunctional right kidney. She underwent nephrectomy by transvaginal NOTES using the endoscope by vaginal access and two ad...

journal_title：European urology

authors： Branco AW,Branco Filho AJ,Kondo W,Noda RW,Kawahara N,Camargo AA,Stunitz LC,Valente J,Rangel M

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Androgen deprivation therapy (ADT) is associated with coronary heart disease and diabetes in men with prostate cancer (PCa); however, controversy exists regarding ADT and cardiovascular mortality (CVM) with limited data for lower risk disease. OBJECTIVE:We conducted a hypothesis-generating retrospective ana...

journal_title：European urology

authors： Voog JC,Paulus R,Shipley WU,Smith MR,McGowan DG,Jones CU,Bahary JP,Zeitzer KL,Souhami L,Leibenhaut MH,Rotman M,Husain SM,Gore E,Raben A,Chafe S,Sandler HM,Efstathiou JA

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Neutrophil-to-lymphocyte ratio (NLR), if elevated, is associated with worse outcomes in several malignancies. OBJECTIVE:Investigation of NLR at baseline and during therapy for metastatic renal cell carcinoma. DESIGN, SETTING, AND PARTICIPANTS:Retrospective analysis of 1199 patients from the International M...

journal_title：European urology

authors： Templeton AJ,Knox JJ,Lin X,Simantov R,Xie W,Lawrence N,Broom R,Fay AP,Rini B,Donskov F,Bjarnason GA,Smoragiewicz M,Kollmannsberger C,Kanesvaran R,Alimohamed N,Hermanns T,Wells JC,Amir E,Choueiri TK,Heng DY

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:The development of the Treatment Satisfaction Scale (TSS) was previously reported (Kubin et al., 2004). OBJECTIVE:This article describes the psychometric validation process and psychometric properties (e.g., reliability, validity, and responsiveness) of TSS. METHODS:Initial patient and partner questionnair...

journal_title：European urology

authors： DiBenedetti DB,Gondek K,Sagnier PP,Kubin M,Marquis P,Keininger D,Fugl-Meyer AR

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:The contact surface area (CSA) of a tumor with adjacent renal parenchyma may determine the complexity and thus the perioperative outcomes of partial nephrectomy (PN). OBJECTIVE:We devised a novel imaging parameter, renal tumor CSA, and correlate it with perioperative outcomes in patients undergoing PN. DES...

journal_title：European urology

authors： Leslie S,Gill IS,de Castro Abreu AL,Rahmanuddin S,Gill KS,Nguyen M,Berger AK,Goh AC,Cai J,Duddalwar VA,Aron M,Desai MM

更新日期：2014-11-01 00:00:00

abstract：:Lower urinary tract symptoms (LUTS) suggestive of benign prostatic obstruction (BPO) are likely to become an increasing burden for health care budgets in the future due to the high prevalence of this condition in the elderly and the ageing of the population. Data on the cost-effectiveness of the available treatment op...

journal_title：European urology

authors： Chapple CR

更新日期：2001-01-01 00:00:00

abstract：:Metastatic urachal carcinoma is a rare, understudied, and aggressive malignancy with limited treatment options. Histologically, urachal carcinomas resemble enteric adenocarcinomas and anecdotally respond to systemic therapies utilized in colorectal cancer. Targeted exome sequencing of archival primary tumor tissue fro...

journal_title：European urology

authors： Collazo-Lorduy A,Castillo-Martin M,Wang L,Patel V,Iyer G,Jordan E,Al-Ahmadie H,Leonard I,Oh WK,Zhu J,McBride RB,Cordon-Cardo C,Solit DB,Sfakianos JP,Galsky MD

更新日期：2016-11-01 00:00:00

abstract：:A retrospective follow-up (range 9.4-22 years, mean 13 years) study of 83 patients with grade I-III (WHO) bladder carcinomas was performed. Nuclear area (mean +/- SD 59.7 +/- 18.7 microns2) and the SD of nuclear area (mean +/- SD 19.7 +/- 13.4 microns2) were determined by using morphometric methods. The SD of nuclear ...

journal_title：European urology

authors： Lipponen PK,Collan Y,Eskelinen MJ,Pesonen E,Sotarauta M

更新日期：1990-01-01 00:00:00

abstract：OBJECTIVES:Pelvic lymph node metastases indicate a poor prognosis for patients with clinically localized prostate cancer. The aim of the study was to investigate the value of extended histopathological techniques considering the extent of pelvic lymphadenectomy and preoperative risk factors. METHODS:Total of 194 patie...

journal_title：European urology

authors： Wawroschek F,Wagner T,Hamm M,Weckermann D,Vogt H,Märkl B,Gordijn R,Harzmann R

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Well-designed randomized controlled trials (RCTs) have the potential to provide high-quality evidence to inform questions of therapy and prevention, but this potential is contingent on the use of appropriate methods and transparent reporting. OBJECTIVE:To systematically assess the quality of urology RCT rep...

journal_title：European urology

authors： Narayan VM,Cone EB,Smith D,Scales CD Jr,Dahm P

更新日期：2016-12-01 00:00:00

abstract：OBJECTIVE:Polytetrafluoroethylene (PTFE) paste has been used for over 30 years to treat urinary incontinence and for 14 years to treat vesicoureteral reflux with little reported morbidity. Some investigators have been concerned by the use of PTFE as the implanted substance, because migration of PTFE particles from the ...

journal_title：European urology

authors： Miyakita H,O'Briain DS,Puri P

更新日期：1998-09-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between neuroendocrine differentiation (NED) status and hormone refractory prostate cancer (HRPC) following hormone therapy based on immunohistochemical study. METHODS:Seventy-two prostate cancer specimens obtained at radical prostatectomy and 21 prostate cancer autopsy specimens...

journal_title：European urology

authors： Hirano D,Okada Y,Minei S,Takimoto Y,Nemoto N

更新日期：2004-05-01 00:00:00

abstract：UNLABELLED:Molecular profiling of individual cancers is key to personalised medicine. While sequencing technologies have required stringent sample collection and handling, recent technical advances offer sequencing from tissues collected in routine practice and tissues already stored in archives. In this paper, we esta...

journal_title：European urology

authors： Liu Y,Noon AP,Aguiar Cabeza E,Shen J,Kuk C,Ilczynski C,Ni R,Sukhu B,Chan K,Barbosa-Morais NL,Hermanns T,Blencowe BJ,Azad A,van der Kwast TH,Catto JW,Zlotta AR,Wrana JL

更新日期：2014-12-01 00:00:00

abstract：:Castration or antiandrogen monotherapies remain options for prostate cancer treatment as only marginal benefits have been demonstrated with combined androgen blockade, although it may be that certain subgroups of patient may benefit. Of the nonsteroidal antiandrogens, bicalutamide 150 mg was as effective as castration...

journal_title：European urology

authors： Schröder FH

更新日期：1998-01-01 00:00:00

abstract：:Univariate and multivariate analyses were performed in 632 patients treated with cisplatin combination chemotherapy for metastatic non-seminomatous testicular germ cell tumours. Multivariately, the most important poor prognosis factors for the prediction of survival were: HCG > or = 10,000 IU/l, lung metastases > or =...

journal_title：European urology

authors： Stoter G,Sleijfer D,Kaye SB,Jones WG,ten Bokkel Huinink WW,de Pauw M,Sylvester R

更新日期：1993-01-01 00:00:00

abstract：OBJECTIVES:A dysregulated mitogen-activated protein kinase (MAPK) pathway plays an important role in various malignancies and is often mediated by mutations in several oncogenes (eg, RAF, RAS). B-RAF mutations, predominantly the specific V600E mutation and additional alterations in exons 11 and 15, were frequently dete...

journal_title：European urology

authors： Burger M,Denzinger S,Hammerschmied C,Tannapfel A,Maderstorfer A,Wieland WF,Hartmann A,Stoehr R

更新日期：2006-11-01 00:00:00

abstract：:Based on experience with over 2,000 patients, the treatment of ureteric stones today relies on extracorporeal shock wave lithotripsy (ESWL) in situ and ureteroscopy with semirigid, ultrathin ureteroscopes combined with pneumatic or laser lithotripsy. All stones in the upper and larger stones in the distal third of the...

journal_title：European urology

authors： Marberger M,Hofbauer J,Türk C,Höbarth K,Albrecht W

更新日期：1994-01-01 00:00:00

abstract：:When a scrotal affection cannot be diagnosed confidently by correlation of clinical history and physical examination, testicular scanning with 99mTc is a useful adjunct diagnostic modality. In vivo labelling of red blood cells with 99mTc was achieved by prior oral administration of 200 mg of stannous chloride. This he...

journal_title：European urology

authors： Rehani MM,Rao MS,Bapna BC,Sharma RR,Rajendran LJ,Subudhi CL,Shrikhande VV,Kumar S,Malik AK,Vaidyanathan S

更新日期：1980-01-01 00:00:00

abstract：INTRODUCTION:Robotic-assisted laparoscopic radical prostatectomy (RLRP) is increasingly becoming an alternative to open and laparoscopic radical prostatectomy in the treatment of localized prostate cancer. RLRP has been associated with low morbidity, short convalescence and comparable oncologic and functional outcomes....

journal_title：European urology

authors： Zorn KC,Gofrit ON,Orvieto MA,Mikhail AA,Zagaja GP,Shalhav AL

更新日期：2007-03-01 00:00:00

abstract：OBJECTIVE:Review the literature on phosphodiesterase type 5 inhibitors (PDE5-Is), addressing critical issues in their current and future use, assessing unanswered questions, and identifying research needs. METHODS:A MEDLINE search was conducted on PDE5-Is, with emphasis on clinical trials and experience, for interpret...

journal_title：European urology

authors： Hatzimouratidis K,Hatzichristou D

更新日期：2007-01-01 00:00:00