Adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) surface.

Abstract:

:The design of bioartificial liver assist device requires an effective attachment of primary hepatocytes on polymeric biomaterials. A better understanding of this cell-surface interaction would aid the optimal choice of biomaterials. In this study, the adhesion contact dynamics of primary hepatocytes on poly(ethylene terephthalate) (PET) surface with grafted poly(acrylic acid) (PAA) and coated collagen is probed with confocal reflectance interference contrast microscopy (C-RICM) in conjunction with phase contrast microscopy. An increase of acrylic acid density from 0 to 12 nmole/cm2 raises both the root-mean-square surface roughness and amount of adsorbed collagen of PET surface. C-RICM demonstrates that hepatocytes form tight adhesion contacts upon seeding on both plain PET and PAA-grafted PET (both with collagen coating) despite the insignificant two-dimensional cell spreading. At two hours after cell seeding, the normalized contact area and adhesion energy of hepatocytes on 12 nmole/cm2 PAA-grafted-PET (with collagen coating) is 27% and 114% higher, respectively, than that on collagen coated plain PET. Interestingly, the growth kinetics of adhesion patch for hepatocyte on PAA-grafted PET with collagen coating is best fitted by R proportional to t0.5 and is significantly different from that on collagen coated plain PET, which is best fitted by R proportional to t0.25. Overall, this study demonstrates the modulation of biophysical response of adherent hepatocytes through the control of the biomaterial surface properties.

journal_name

Biomaterials

journal_title

Biomaterials

authors

Tan WJ,Teo GP,Liao K,Leong KW,Mao HQ,Chan V

doi

10.1016/j.biomaterials.2004.03.041

keywords:

subject

Has Abstract

pub_date

2005-03-01 00:00:00

pages

891-8

issue

8

eissn

0142-9612

issn

1878-5905

pii

S0142961204002923

journal_volume

26

pub_type

杂志文章
  • Microstructure and mechanical properties of hydroxyapatite ceramics with zirconia dispersion prepared by post-sintering.

    abstract::Hydroxyapatite ceramics with zirconia dispersion from fine powders synthesized hydrothermally were post-sintered at 1000-1300 degrees C under 200 MPa of argon for 1 h without capsules, after normal sintering in air at 1200 degrees C for 3 h. Densification was most significant with post-sintering at 1200 degrees C. Fra...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:

    authors: Ioku K,Yoshimura M,Somiya S

    更新日期:1990-01-01 00:00:00

  • Crosslink density, oxidation and chain scission in retrieved, highly cross-linked UHMWPE tibial bearings.

    abstract::Irradiated, thermally stabilized, highly cross-linked UHMWPE bearings have demonstrated superior wear performance and improved in vitro oxidation resistance compared with terminally gamma-sterilized bearings, yet retrieval analysis reveals unanticipated in vivo oxidation in these materials despite fewer or no measurab...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2014.02.019

    authors: Reinitz SD,Currier BH,Levine RA,Van Citters DW

    更新日期:2014-05-01 00:00:00

  • Challenge to the concept that UHMWPE acetabular components oxidize in vivo.

    abstract::Severe wear of the ultra-high molecular weight polyethylene (UHMWPE) components of total joint replacements limits their long-term success. In previous studies, the infrared spectra obtained on retrieved UHMWPE components were interpreted as evidence that the UHMWPE oxidizes in vivo. In direct contrast, infrared spect...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/0142-9612(93)90062-7

    authors: James SP,Blazka S,Merrill EW,Jasty M,Lee KR,Bragdon CR,Harris WH

    更新日期:1993-07-01 00:00:00

  • Proliferation and osteoblastic differentiation of human bone marrow-derived stromal cells on akermanite-bioactive ceramics.

    abstract::In the present study, the effects of a calcium magnesium silicate bioactive ceramic (akermanite) on proliferation and osteoblastic differentiation of human bone marrow stromal cells (hBMSC) have been investigated and compared with the classical ceramic (beta-tricalcium phosphate, beta-TCP). Akermanite and beta-TCP dis...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2006.07.027

    authors: Sun H,Wu C,Dai K,Chang J,Tang T

    更新日期:2006-11-01 00:00:00

  • Fluorophore-labeled nanocapsules displaying IgG Fc-binding domains for the simultaneous detection of multiple antigens.

    abstract::Simultaneous detection of multiple antigens by conventional immunological methods has been limited by the source of primary antibodies. Each antibody should be derived from a different host species (or subclass of immunoglobulin (Ig)) for suppressing the cross-reactions of secondary antibodies. Here we describe an inn...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2011.08.012

    authors: Iijima M,Matsuzaki T,Yoshimoto N,Niimi T,Tanizawa K,Kuroda S

    更新日期:2011-12-01 00:00:00

  • In vivo cytokine secretion and NF-kappaB activation around titanium and copper implants.

    abstract::The early biological response at titanium (Ti), copper (Cu)-coated Ti and sham sites was evaluated in an in vivo rat model. Material surface chemical and topographical properties were characterized using Auger electron spectroscopy, energy dispersive X-ray spectroscopy and interferometry, respectively. The number of l...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2004.02.066

    authors: Suska F,Gretzer C,Esposito M,Emanuelsson L,Wennerberg A,Tengvall P,Thomsen P

    更新日期:2005-02-01 00:00:00

  • The role of trabecular demineralized bone in combination with perichondrium in the generation of cartilage grafts.

    abstract::The use of a composite graft of bovine trabecular demineralized bone matrix (DBM) and perichondrium has been found a reliable method for in vivo generation of cartilage. In the present study, the mechanism whereby this commercially available matrix increases cartilage formation was investigated. First, the time course...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/s0142-9612(98)00165-3

    authors: van Osch GJ,ten Koppel PG,van der Veen SW,Poppe P,Burger EH,Verwoerd-Verhoef HL

    更新日期:1999-02-01 00:00:00

  • Characterization of metabolic changes associated with the functional development of 3D engineered tissues by non-invasive, dynamic measurement of individual cell redox ratios.

    abstract::Non-invasive approaches to assess tissue function could improve significantly current methods to diagnose diseases and optimize engineered tissues. In this study, we describe a two-photon excited fluorescence microscopy approach that relies entirely on endogenous fluorophores to dynamically quantify functional metabol...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2012.04.024

    authors: Quinn KP,Bellas E,Fourligas N,Lee K,Kaplan DL,Georgakoudi I

    更新日期:2012-07-01 00:00:00

  • Analgesic drug delivery via recombinant tissue plasminogen activator and microRNA-183-triggered opening of the blood-nerve barrier.

    abstract::The peripheral nerve contains three barriers which include the blood-nerve barrier consisting of endoneurial vessels and the perineurium as well as autotypic junctions in Schwann cells. The perineurium prevents diffusion of perineurally injected drugs that can be used for selective regional pain control. It is compose...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2015.11.053

    authors: Yang S,Krug SM,Heitmann J,Hu L,Reinhold AK,Sauer S,Bosten J,Sommer C,Fromm M,Brack A,Rittner HL

    更新日期:2016-03-01 00:00:00

  • E-jet 3D printed drug delivery implants to inhibit growth and metastasis of orthotopic breast cancer.

    abstract::Drug-loaded implants have attracted considerable attention in cancer treatment due to their precise delivery of drugs into cancer tissues. Contrary to injected drug delivery, the application of drug-loaded implants remains underutilized given the requirement for a surgical operation. Nevertheless, drug-loaded implants...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2019.119618

    authors: Yang Y,Qiao X,Huang R,Chen H,Shi X,Wang J,Tan W,Tan Z

    更新日期:2020-02-01 00:00:00

  • Synthesis and properties of novel block copolymers containing poly(lactic-glycolic acid) and poly(ethyleneglycol) segments.

    abstract::A synthetic process for obtaining high-molecular-weight block copolymers containing poly(lactic-glycolic acid) and poly(ethylene glycol) segments has been established. This process involves the reaction of poly(ethylene glycols) with phosgene, followed by polycondensation of the resulting alpha, omega-bis(chloroformat...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/0142-9612(95)96879-5

    authors: Ferruti P,Penco M,D'Addato P,Ranucci E,Deghenghi R

    更新日期:1995-12-01 00:00:00

  • Assembly of lung progenitors into developmentally-inspired geometry drives differentiation via cellular tension.

    abstract::During organogenesis groups of differentiating cells self-organize into a series of structural intermediates with defined architectural forms. Evidence is emerging that such architectural forms are important in guiding cell fate, yet in vitro methods to guide cell fate have focused primarily on un-patterned exposure o...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2020.120128

    authors: Soleas JP,D'Arcangelo E,Huang L,Karoubi G,Nostro MC,McGuigan AP,Waddell TK

    更新日期:2020-09-01 00:00:00

  • Influence of grinding, sandblasting, polishing and heat treatment on the flexural strength of a glass-infiltrated alumina-reinforced dental ceramic.

    abstract::The influence of processing-introduced flaws and heat treatment on the strength degradation of the dental core material has recently been observed. However, there are insufficient studies which investigate the role of grinding, grinding orientation, sandblasting, polishing and heat treatment on the strength of In-Cera...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2003.08.056

    authors: Guazzato M,Albakry M,Quach L,Swain MV

    更新日期:2004-05-01 00:00:00

  • Decellularized kidney scaffold-mediated renal regeneration.

    abstract::Renal regeneration approaches offer great potential for the treatment of chronic kidney disease, but their availability remains limited by the clinical challenges they pose. In the present study, we used continuous detergent perfusion to generate decellularized (DC) rat kidney scaffolds. The scaffolds retained intact ...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2014.04.074

    authors: Yu YL,Shao YK,Ding YQ,Lin KZ,Chen B,Zhang HZ,Zhao LN,Wang ZB,Zhang JS,Tang ML,Mei J

    更新日期:2014-08-01 00:00:00

  • Knowledge gaps in immune response and immunotherapy involving nanomaterials: Databases and artificial intelligence for material design.

    abstract::Exploring the interactions between the immune system and nanomaterials (NMs) is critical for designing effective and safe NMs, but large knowledge gaps remain to be filled prior to clinical applications (e.g., immunotherapy). The lack of databases on interactions between the immune system and NMs affects the discovery...

    journal_title:Biomaterials

    pub_type: 杂志文章,评审

    doi:10.1016/j.biomaterials.2020.120469

    authors: Feng R,Yu F,Xu J,Hu X

    更新日期:2021-01-01 00:00:00

  • The surface properties of nanocrystalline diamond and nanoparticulate diamond powder and their suitability as cell growth support surfaces.

    abstract::Nanocrystalline diamond (NCD) films and nanoparticulate diamond powder (DP) are the two main representatives of diamond at the nanoscale. This study was designed to investigate the suitability of these biomaterials as cell growth supports and to determine surface characteristic properties best suited to cell attachmen...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2008.07.023

    authors: Lechleitner T,Klauser F,Seppi T,Lechner J,Jennings P,Perco P,Mayer B,Steinmüller-Nethl D,Preiner J,Hinterdorfer P,Hermann M,Bertel E,Pfaller K,Pfaller W

    更新日期:2008-11-01 00:00:00

  • Experimental evaluation of a resorbable intramedullary plug for cemented total hip replacement.

    abstract::In order to evaluate degradation kinetics and biocompatibility of a resorbable poly(D,L-lactic acid) (PDLLA) plug for total cemented hip prostheses, an experimental in vitro and in vivo study was carried out. Degradation rate studies were performed in Ringer solution and after in vivo plug implantation in the femoral ...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/s0142-9612(97)00014-8

    authors: Giardino R,Fini M,Aldini NN,Giavaresi G,Rocca M,Orienti L,de Lollis A,Fambri L

    更新日期:1997-07-01 00:00:00

  • Thermal dimensional behavior of dental ceramics.

    abstract::The aim of this study was to characterize the relation of dimensional changes of dental ceramic materials as function of temperature. The thermal dimensional behavior of one glass ceramic core, four commercially available veneering porcelains and two experimental veneering porcelain materials was determined on cooling...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2003.09.027

    authors: Isgrò G,Kleverlaan CJ,Wang H,Feilzer AJ

    更新日期:2004-05-01 00:00:00

  • Non-viral gene delivery of DNA polyplexed with nanoparticles transfected into human mesenchymal stem cells.

    abstract::Human mesenchymal stem cells (hMSCs) represent a potent target for gene delivery for both stem cell differentiation applications and clinical therapies. However, it has, thus far, proven difficult to develop delivery vehicles that increase the efficiency of gene delivery to hMSCs, due to several problematic issues. We...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2009.09.023

    authors: Park JS,Na K,Woo DG,Yang HN,Kim JM,Kim JH,Chung HM,Park KH

    更新日期:2010-01-01 00:00:00

  • Constitutive models for impacted morsellised cortico-cancellous bone.

    abstract::Constitutive models are developed, based on the results of confined compression testing, to describe the visco-elastic, and non-linear elasto-plastic behaviour of morsellised cortico-cancellous bone (MCB). It is found that the elastic modulus, E of MCB can be expressed as a linear function of the applied pressure, p. ...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2005.10.034

    authors: Phillips A,Pankaj P,May F,Taylor K,Howie C,Usmani A

    更新日期:2006-03-01 00:00:00

  • MiRNA-124 induces neuroprotection and functional improvement after focal cerebral ischemia.

    abstract::microRNA-124 (miR-124), the most abundant miRNA of the CNS, was recently shown to modulate the polarization of activated microglia and infiltrating macrophages towards the anti-inflammatory M2 phenotype and protect neurons in various ways after brain disease. In ischemic stroke, microglia and macrophages of a detrimen...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2016.03.025

    authors: Hamzei Taj S,Kho W,Riou A,Wiedermann D,Hoehn M

    更新日期:2016-06-01 00:00:00

  • Genetically encoded FRET-based biosensor for imaging MMP-9 activity.

    abstract::A genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensor that continuously monitors matrix metalloproteinase 9 (MMP-9) activity was developed. MMP-9 is an extracellularly acting endopeptidase with a prominent role in development, learning and memory, cancer metastasis, and stroke. To assess the b...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2013.11.033

    authors: Stawarski M,Rutkowska-Wlodarczyk I,Zeug A,Bijata M,Madej H,Kaczmarek L,Wlodarczyk J

    更新日期:2014-02-01 00:00:00

  • Enhanced cell survival of melanocyte spheroids in serum starvation condition.

    abstract::Autologous melanocyte transplantation for vitiligo treatment by use of melanocyte suspension has drawbacks including cell damage in cell preparation and transportation, difficult manipulation and low engraftment rate in acral vitiligious lesions. We have proposed the concept of cellular patch as an alternative solutio...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2005.08.031

    authors: Lin SJ,Jee SH,Hsiao WC,Yu HS,Tsai TF,Chen JS,Hsu CJ,Young TH

    更新日期:2006-03-01 00:00:00

  • The in vivo performance of a sol-gel glass and a glass-ceramic in the treatment of limited bone defects.

    abstract::The in vivo evaluation, in New Zealand rabbits, of a SiO(2)-P(2)O(5)-CaO sol-gel glass and a SiO(2)-P(2)O(5)-CaO-MgO glass-ceramic, both bioactive in Kokubo's simulated body fluid (SBF), is presented. Bone defects, performed in the lateral aspect of distal right femoral epiphysis, 5mm in diameter and 4mm in depth, wer...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2003.12.009

    authors: Gil-Albarova J,Garrido-Lahiguera R,Salinas AJ,Román J,Bueno-Lozano AL,Gil-Albarova R,Vallet-Regí M

    更新日期:2004-08-01 00:00:00

  • Preparation of bioactive Ti6Al4V surfaces by a simple method.

    abstract::Boiling diluted alkali incubation was found to be an effective way to prepare bioactive Ti6Al4V surfaces, whether polished or not, as indicated in vitro after immersion in two different supersaturated calcification solutions (SCSs). The induction of calcium phosphate (Ca-P) precipitation from the SCSs is most probably...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/s0142-9612(97)00232-9

    authors: Wen HB,de Wijn JR,Cui FZ,de Groot K

    更新日期:1998-01-01 00:00:00

  • Induction of ROS, mitochondrial damage and autophagy in lung epithelial cancer cells by iron oxide nanoparticles.

    abstract::Autophagy has attracted a great deal of research interest in tumor therapy in recent years. An attempt was made in this direction and now we report that iron oxide NPs synthesized by us selectively induce autophagy in cancer cells (A549) and not in normal cells (IMR-90). It was also noteworthy that autophagy correlate...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2011.10.080

    authors: Khan MI,Mohammad A,Patil G,Naqvi SA,Chauhan LK,Ahmad I

    更新日期:2012-02-01 00:00:00

  • Extracellular matrix deposition of bone marrow stroma enhanced by macromolecular crowding.

    abstract::Decellularized extracellular matrices (ECM) from in vitro cell cultures can serve as in vivo-like matrix scaffolds for modulating cell-ECM interactions. Macromolecular crowding (MMC), the supplementation of synthetic or naturally occurring molecules resulting in excluded volume effects (EVE), has been demonstrated to ...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2015.09.014

    authors: Prewitz MC,Stißel A,Friedrichs J,Träber N,Vogler S,Bornhäuser M,Werner C

    更新日期:2015-12-01 00:00:00

  • The activity against Ehrlich's ascites tumors of doxorubicin contained in self assembled, cell receptor targeted nanoparticle with simultaneous oral delivery of the green tea polyphenol epigallocatechin-3-gallate.

    abstract::Doxorubicin (DOX) is a well-known anticancer drug used for the treatment of a wide variety of cancers. However, undesired toxicity of DOX limits its uses. To address the issue of minimizing toxicity of DOX by making it targeted towards cancer cells, DOX was entrapped in self-assembled 6-O-(3-hexadecyloxy-2-hydroxyprop...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2012.12.044

    authors: Ray L,Kumar P,Gupta KC

    更新日期:2013-04-01 00:00:00

  • Reconfiguring the architectures of cationic helical polypeptides to control non-viral gene delivery.

    abstract::Poly(γ-4-((2-(piperidin-1-yl)ethyl)aminomethyl)benzyl-l-glutamate) (PPABLG), a cationic helical polypeptide, has been recently developed by us as an effective non-viral gene delivery vector. In attempts to elucidate the effect of molecular architecture on the gene delivery efficiencies and thereby identify a potential...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/j.biomaterials.2012.11.064

    authors: Yin L,Song Z,Kim KH,Zheng N,Tang H,Lu H,Gabrielson N,Cheng J

    更新日期:2013-03-01 00:00:00

  • Adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene.

    abstract::We studied the adhesion and proliferation of human endothelial cells on photochemically modified polytetrafluoroethylene samples. The polymer surfaces were modified by exposure to the ultraviolet light of a Xe(2)(*)-excimer lamp at a wavelength of 172 nm in an ammonia atmosphere. Treatment times were between 10 and 20...

    journal_title:Biomaterials

    pub_type: 杂志文章

    doi:10.1016/s0142-9612(03)00460-5

    authors: Gumpenberger T,Heitz J,Bäuerle D,Kahr H,Graz I,Romanin C,Svorcik V,Leisch F

    更新日期:2003-12-01 00:00:00