Abstract:
:The enantioselective hydrolysis of insoluble (R,S)-ketoprofen ethyl ester to the optically active (S)-ketoprofen was carried out in a dispersed aqueous lipase reaction system induced by the inclusion of chiral cyclodextrins for complexation of the substrate. Hydroxypropyl-beta-cyclodextrin was the most effective chiral selector and disperser giving an enantiomeric excess and conversion yield of 0.99 and 0.49, respectively.
journal_name
Biotechnol Lettjournal_title
Biotechnology lettersauthors
Kim SH,Kim TK,Shin GS,Lee KW,Shin HD,Lee YHdoi
10.1023/b:bile.0000030040.13828.d7keywords:
subject
Has Abstractpub_date
2004-06-01 00:00:00pages
965-9issue
12eissn
0141-5492issn
1573-6776pii
5275757journal_volume
26pub_type
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