The effect of halides (NaCl and NaI) on in vitro pancreatic elastase activity.

abstract：:For many years we have investigated the earliest crystal formations of different developing hard tissues (matrix vesicle, bone, dentine, enamel, etc.) by different electron microscopic measurements. It was observed that primarily Ca-phosphate (apatite) "chains," composed of nanometer sized particles (dots, islands), e...

journal_title：Connective tissue research

authors： Höhling HJ,Arnold S,Barckhaus RH,Plate U,Wiesmann HP

更新日期：1995-01-01 00:00:00

abstract：PURPOSE/AIM:Glutamate is one of the signaling molecules responsible for transmission in the central nervous system. Periodontal ligament (PDL) cells were recently reported to express metabotropic glutamate receptors (mGluRs). However, the functions of mGluR signaling in PDL cells or PDL-related cells remain largely unk...

journal_title：Connective tissue research

authors： Kanaya S,Komatsu H,Shimauchi H,Nemoto E

更新日期：2016-09-01 00:00:00

abstract：:The use of electron microscopic observations to characterize the state of aggregation of collagen molecules in solution has been examined from the point of view that the observed structures must be compatible with the physical chemical properties of the solution. The common procedure of addition of droplets of a colla...

journal_title：Connective tissue research

authors： Schwartz D,Veis A

更新日期：1978-01-01 00:00:00

abstract：:The pharmacokinetics of desmosine following a 5 mg intravenous dose was determined in five sheep. The biological half-life (t 1/2 beta) of desmosine varied between 81-489 min. Urinary recovery of unchanged desmosine indicated that the compound is not extensively metabolized and that the primary route of elimination is...

journal_title：Connective tissue research

authors： Verma PS,Hoyt RF Jr,Jackson AJ,Phillips YY

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:This study proposes to evaluate, by means of microtomographic analysis, the topical potential of raloxifene combined with BioGran® through the sonochemical method in the repair of critical bone defects in the calvaria of rats. The hypothesis was that the homogenization of Raloxifene to Biogran at the 20% conc...

journal_title：Connective tissue research

authors： Lisboa-Filho PN,Gomes-Ferreira PHS,Batista FRS,Momesso GAC,Faverani LP,Okamoto R

更新日期：2018-12-01 00:00:00

abstract：:The basic subunit of cartilage proteoglycan consists of multiple glycosaminoglycan chains covalently attached to a core protein. It is unclear as to whether there is a single core protein or multiple different core proteins, since previous studies using either chondroitinase or testicular hyaluronidase to enzymaticall...

journal_title：Connective tissue research

authors： Keiser HD,Hatcher VB

更新日期：1977-01-01 00:00:00

abstract：:Anterior cruciate ligament (ACL) has poor healing ability and an injured ACL would induce the degeneration of other intra-articular connective tissues. However, the coordinated expression and activities of matrix metalloproteinase (MMPs) in intra-articular tissues induced by ACL rupture were poorly understood. With a ...

journal_title：Connective tissue research

authors： Tang Z,Yang L,Zhang J,Xue R,Wang Y,Chen PC,Sung KL

更新日期：2009-01-01 00:00:00

abstract：:The menisci are intricately organized structures that perform many tasks in the knee. We review their structure and function and introduce new data about their tibial and femoral surfaces. As the femur and tibia approach each other when the knee is bearing load, circumferential tension develops in the menisci, enablin...

journal_title：Connective tissue research

authors： Andrews SHJ,Adesida AB,Abusara Z,Shrive NG

更新日期：2017-01-01 00:00:00

abstract：:Purpose/Aim: Cementogenesis is a critical step in periodontal tissue regeneration given the essential role of cementum in anchoring teeth to the alveolar bone. This study is designed to achieve integrated cementum formation on the root surfaces of human teeth using growth factor-releasing scaffolds with periodontal li...

journal_title：Connective tissue research

authors： Cho H,Tarafder S,Fogge M,Kao K,Lee CH

更新日期：2016-11-01 00:00:00

abstract：:Growth and differentiation factor-5 (GDF-5) is known to induce tendon tissue and stimulate tendon healing. The hypothesis was that adenoviral GDF-5 transfer leads to transitory transgene expression and improves Achilles tendon healing. In vitro experiments were first performed with rat tenocytes. Transgene expression ...

journal_title：Connective tissue research

authors： Rickert M,Wang H,Wieloch P,Lorenz H,Steck E,Sabo D,Richter W

更新日期：2005-01-01 00:00:00

abstract：:??Although injuries to the medial collateral ligament (MCL) can heal functionally without surgical intervention, the collagen fibers in the healing tissue remain compromised. The molecular basis for this poor healing potential was investigated by examining extracellular matrix-modifying molecules such as bone morphoge...

journal_title：Connective tissue research

authors： Achari Y,Chin JW,Heard BJ,Rattner JB,Shrive NG,Frank CB,Hart DA

更新日期：2011-01-01 00:00:00

abstract：:Tubulointerstitial nephritis antigen (TIN-ag) is a recently described basement membrane component reactive with autoantibodies in some forms of autoimmune mediated tubulointerstitial nephritis. Immunofluorescence studies using polyclonal and monoclonal antibodies have indicated a restrictive tissue distribution for TI...

journal_title：Connective tissue research

authors： Nelson TR,Butkowski RJ,Michael AF,Charonis AS

更新日期：1997-01-01 00:00:00

abstract：:Cumulative damage to long-lived connective tissue proteins play a key role in the development of age-related human diseases such as cardiovascular stiffening and age-related macular degeneration. The processes that result in the accumulation of increasingly insoluble, undigestible damaged collagen are only partially k...

journal_title：Connective tissue research

authors： Paik DC,Saito LY,Sugirtharaj DD,Holmes JW

更新日期：2006-01-01 00:00:00

abstract：:The purpose of this study was to investigate overall degradative changes occurring to enamel matrix proteins in small, freeze-dried pieces of rat incisor enamel homogenized and incubated directly for 0-48 hours in a synthetic enamel fluid solution (165 mM total ionic strength with 0.153 mM calcium chloride) versus oth...

journal_title：Connective tissue research

authors： Smith CE,Chen WY

更新日期：1998-01-01 00:00:00

abstract：:The critical remembrance of my research activity displays aspects of inconsequence and mental rigidity. Particular probative examples are called to mind. Unpublished observations concerning immortalized dental cells are summarized. As a consequence, if I could start again, I would improve several aspects of my behavio...

journal_title：Connective tissue research

authors： Ruch JV

更新日期：2002-01-01 00:00:00

abstract：AIM OF THE STUDY:To further elucidate the pathogenesis of systemic sclerosis (SSc) an experimental avian model was used. The University of California at Davis line 200 (UCD-200) chickens spontaneously develop a SSc-like disease that has most features of human SSc with vascular effects, inflammation, autoimmunity, and f...

journal_title：Connective tissue research

authors： Kerje S,Hellman U,Do L,Larsson G,Kämpe O,Engström-Laurent A,Lindqvist U

更新日期：2016-09-01 00:00:00

abstract：UNLABELLED:PURPOSE/AIMS OF THE STUDY: Bone's hierarchical structure can be visualized using a variety of methods. Many techniques, such as light and electron microscopy generate two-dimensional (2D) images, while micro-computed tomography (µCT) allows a direct representation of the three-dimensional (3D) structure. In ...

journal_title：Connective tissue research

authors： Hoerth RM,Baum D,Knötel D,Prohaska S,Willie BM,Duda GN,Hege HC,Fratzl P,Wagermaier W

更新日期：2015-04-01 00:00:00

abstract：:Bone and dentin contain many phosphoproteins in their extracellular matrix. It has been postulated that the anionic character of these proteins, and the presence of phosphate groups in particular, is important for various functions related to biomineralization. Phosphophoryns (PP), are the most highly phosphorylated d...

journal_title：Connective tissue research

authors： Sfeir C,Veis A

更新日期：1996-01-01 00:00:00

abstract：:Oral mandibular epithelium determines the position and number of tooth organs. Cranial neural crest-derived ectomesenchyme provides inductive signals for (i) tooth shape, and (ii) sequential determination and expression of several different epithelial-derived enamel proteins. Inductive signalling follows a precise seq...

journal_title：Connective tissue research

authors： Slavkin HC

更新日期：1989-01-01 00:00:00

abstract：:Syndecan-4 is emerging as an important player in cell interaction with the extracellular environment and has been shown to be involved in the progression of intervertebral disc degeneration. However, the mechanism of syndecan-4 regulation by TNF-α and the role of TGF-β1 in regulating syndecan-4 expression remain poorl...

journal_title：Connective tissue research

authors： Yang H,Liu H,Li X,Pan H,Li Z,Wang J,Zheng Z

更新日期：2015-01-01 00:00:00

abstract：:Osteoarthritis (OA) is typically managed in late stages by replacement of the articular cartilage surface with a prosthesis as an effective, though undesirable outcome. As an alternative, hydrogel implants or growth factor treatments are currently of great interest in the tissue engineering community, and scaffold mat...

journal_title：Connective tissue research

authors： McCreery KP,Calve S,Neu CP

更新日期：2020-05-01 00:00:00

abstract：:Cells derived from organ-explant culture of the cartilaginous component of osteochondrophytic spurs of human femoral heads were incubated with [35S]-sulfate in order to study sulfated proteoglycan biosynthesis in vitro. Secondary monolayer cultures incorporated [35S]-sulfate into macromolecules which were recovered in...

journal_title：Connective tissue research

authors： Malemud CJ,Moskowitz RW,Goldberg VM

更新日期：1984-01-01 00:00:00

abstract：:Abnormal polyanion metabolism in cultured fibroblasts from patients with pseudoxanthoma elasticum (PXE) was studied by incubating normal and PXE fibroblasts in culture medium containing 35SO4 for 96 hr and measuring differences in secreted 35SO4-labelled proteoglycans (35S-PG). PXE medium contained less high molecular...

journal_title：Connective tissue research

authors： Gordon SG,Overland M,Foley J

更新日期：1978-01-01 00:00:00

abstract：:A detailed analysis of the D-period and axial electron density distribution of cornea and tendon collagen was carried out by means of X-ray diffraction and electron microscopy. Ultrastructural observations were made on replicas of freeze fractured and deep-etched specimens. Synchrotron radiation was used to obtain hig...

journal_title：Connective tissue research

authors： Marchini M,Morocutti M,Ruggeri A,Koch MH,Bigi A,Roveri N

更新日期：1986-01-01 00:00:00

abstract：:Since hyaluronan anchors the proteoglycan-rich pericellular matrix to chondrocytes, hyaluronan-cell interactions may direct cartilage matrix assembly. To test this hypothesis, the competitive binding of hyaluronan hexasaccharides for native hyaluronan during matrix assembly, accumulation and retention in embryonic car...

journal_title：Connective tissue research

authors： Maleski MP,Knudson CB

更新日期：1996-01-01 00:00:00

abstract：:Purpose: Complications including arthrofibrosis have been reported after anterior cruciate ligament reconstruction (ACLR) even under accelerated rehabilitation. To overcome this, we developed an animal model of ACLR-induced arthrofibrosis without immobilization.Materials and Methods: Thirteen male Wistar rats were div...

journal_title：Connective tissue research

authors： Kaneguchi A,Ozawa J,Minamimoto K,Yamaoka K

更新日期：2019-11-26 00:00:00

abstract：:This study was designed to determine the effects of pulsed electromagnetic fields (PEMF) on the mRNA expression of the receptor activator of NF-kappa-B (RANK) and carbonic anhydrase II (CA II) in ovariectomized rat osteoclast-like cells. Marrow cells were harvested from femora and tibiae of rats, from which the ovarie...

journal_title：Connective tissue research

authors： Chen J,He HC,Xia QJ,Huang LQ,Hu YJ,He CQ

更新日期：2010-01-01 00:00:00

abstract：:The structural and immunological properties of the glycosaminoglycans and the core proteins of bovine nasal cartilage proteoglycan and the proteoglycans produced by rabbit articular chondrocytes in spinner and monolayer culture were compared. Culture medium with 35SO4- or 3H-serine-labeled proteoglycan was mixed with ...

journal_title：Connective tissue research

authors： Keiser HD,Malemud CJ

更新日期：1983-01-01 00:00:00

abstract：:Oriented fibers, arising from the self assembly of collagen, may be produced from in vitro fibrillogenesis of soluble collagen with gradients of fibrillogenic potential. These gradients may be introduced by either concentration gradients of pronase-treated collagen or of arginine which, in turn, create concentration g...

journal_title：Connective tissue research

authors： Ghosh S,Comper WD

更新日期：1988-01-01 00:00:00

abstract：:STR/ort mice develop a naturally occurring osteoarthritis (OA) of the knee joints. However, the evaluation of early OA changes has been difficult due to variability caused by gender, individual differences, and differences between the right and left lower limbs. The objective of this study was to analyze the variabili...

journal_title：Connective tissue research

authors： Naruse K,Urabe K,Jiang SX,Uchida K,Kozai Y,Minehara H,Mikuni-Takagaki Y,Kashima I,Itoman M

更新日期：2009-01-01 00:00:00