A rat model of arthrofibrosis developed after anterior cruciate ligament reconstruction without rigid joint immobilization.

abstract：:The oxidation of an elastin substrate by highly purified bovine aortic lysyl oxidase (LO) is markedly influenced by amphiphilic molecules known to bind to elastin. Negatively charged elastin ligands, including fatty acids, bile salts or sodium dodecyl sulfate can completely inhibit the oxidation of lysine in elastin, ...

journal_title：Connective tissue research

authors： Kagan HM,Simpson DE,Tseng L

更新日期：1981-01-01 00:00:00

abstract：:To extend previous studies on the apparent acceleration of collagen aging in diabetes mellitus, dura collagen from human adults of different ages, with and without diabetes, was processed to yield soluble and insoluble fractions. Insoluble fractions were cleaved by cyanogen bromide. Release of peptides from insoluble ...

journal_title：Connective tissue research

authors： Kohn RR

更新日期：1983-01-01 00:00:00

abstract：AIM:To investigate the effect of extracellular matrix (ECM) proteins on characteristics of mesenchymal stem cells (MSCs) and tendon-derived cells (TDCs). MATERIALS AND METHODS:MSCs and TDCs, cultured in a monolayer (2D) or hydrogels (3D), with or without ECM protein supplementation, and on a non-viable native tendon (...

journal_title：Connective tissue research

authors： Clements LE,Garvican ER,Dudhia J,Smith RK

更新日期：2016-11-01 00:00:00

abstract：:A homogeneous preparation of glycoprotein (apparent molecular weight 34,000) has been isolated from bovine ligamentum nuchae by treatment of the tissue with 5 M guanidine HCl and 2-mercaptoethanol. The preparation exhibits amine oxidase activity which is only marginally inhibited by beta-aminopropionitrile. ...

journal_title：Connective tissue research

authors： Serafini-Fracassini A,Ventrella G,Griffiths R,Hinnie J

更新日期：1981-01-01 00:00:00

abstract：:The effects of various avocado oils on collagen metabolism in skin were studied in growing rats fed diets containing 10% (w/w) of the tested oils. Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, its unsaponifiables or the avocado seed oil, showed significant increases in soluble collage...

journal_title：Connective tissue research

authors： Werman MJ,Mokady S,Nimni ME,Neeman I

更新日期：1991-01-01 00:00:00

abstract：:A theoretical expression has been derived for the mean collagen fibril length in tendon based on the assumption that collagen fibrils originate in cell surface invaginations and terminate either at some remote cell surface or another collagen fibril bundle. The expression thus determined requires knowledge of the effe...

journal_title：Connective tissue research

authors： Craig AS,Birtles MJ,Conway JF,Parry DA

更新日期：1989-01-01 00:00:00

abstract：:Tubulointerstitial nephritis antigen (TIN-ag) is a recently described basement membrane component reactive with autoantibodies in some forms of autoimmune mediated tubulointerstitial nephritis. Immunofluorescence studies using polyclonal and monoclonal antibodies have indicated a restrictive tissue distribution for TI...

journal_title：Connective tissue research

authors： Nelson TR,Butkowski RJ,Michael AF,Charonis AS

更新日期：1997-01-01 00:00:00

abstract：PURPOSE:Orthodontic tooth movement occurs during the bone remodeling induced by therapeutic mechanical strain. It is important to investigate the relation between the strength of mechanical stress and bone formation activity. The aim of this study was to determine the effect of high-magnitude mechanical strain on bone ...

journal_title：Connective tissue research

authors： Fushiki R,Mayahara K,Ogawa M,Takahashi Y,Karasawa Y,Tsurumachi N,Tamura T,Shimizu N

更新日期：2015-01-01 00:00:00

abstract：:This study evaluated the effect of short bouts of stretching on the soleus muscle after immobilization, by measuring the birefringence of the intramuscular connective tissue (ICT) and the muscle fiber area. Thirty rats were divided into five groups: the left soleus was immobilized in the shortened position; after immo...

journal_title：Connective tissue research

authors： Coutinho EL,DeLuca C,Salvini TF,Vidal BC

更新日期：2006-01-01 00:00:00

abstract：:By using ultramorphological and biochemical methods, we analyzed the regional differences between the three parts of the equine superficial digital flexor tendon (SDFT), namely, the myotendinous junction (MTJ), middle metacarpal (mM), and osteotendinous junction (OTJ). Cross-sectional images showed unique distribution...

journal_title：Connective tissue research

authors： Watanabe T,Imamura Y,Hosaka Y,Ueda H,Takehana K

更新日期：2007-01-01 00:00:00

abstract：:Ligaments have limited regenerative potential and as a consequence, repair is protracted and results in a mechanically inferior tissue more scar-like than native ligament. We previously reported that a single injection of interleukin-1 receptor antagonist (IL-1Ra) delivered at the time of injury, decreased the number ...

journal_title：Connective tissue research

authors： Chamberlain CS,Leiferman EM,Frisch KE,Duenwald-Kuehl SE,Brickson SL,Murphy WL,Baer GS,Vanderby R

更新日期：2014-06-01 00:00:00

abstract：:Bone sialoprotein is a 34 kDa phosphorylated and sulphated glycoprotein that is essentially unique to mineralizing connective tissues. Recent studies on the developmental expression of BSP mRNA and the temporo-spatial appearance of the protein during bone formation in vivo and in vitro have demonstrated that BSP is ex...

journal_title：Connective tissue research

authors： Sodek J,Li JJ,Kim RH,Ogata Y,Yamauchi M

更新日期：1996-01-01 00:00:00

abstract：:Purpose/Aim: Elevated serum phosphate is one of the major factors contributing to vascular calcification. Studies suggested that extracellular vesicles released from vascular smooth muscle cells significantly contribute to the initiation and progression of this pathology. Recently, we have demonstrated that elevated p...

journal_title：Connective tissue research

authors： Chaudhary SC,Khalid S,Smethurst V,Monier D,Mobley J,Huet A,Conway JF,Napierala D

更新日期：2018-12-01 00:00:00

abstract：:Idiopathic pulmonary fibrosis (IPF) is associated with aberrant repair, persistence of collagen deposition, and the development of vascular remodeling. However, the role of angiogenesis in the pathogenesis of IPF is still undetermined. The aim of this study was to evaluate the combined mRNA expression of vascular endo...

journal_title：Connective tissue research

authors： Antoniou KM,Soufla G,Lymbouridou R,Economidou F,Lasithiotaki I,Manousakis M,Drositis I,Spandidos DA,Siafakas NM

更新日期：2010-01-01 00:00:00

abstract：:Glycosaminoglycan synthesis by cells cultured from nodule or band tissues of patients with Dupuytren's disease was compared with that of skin fibroblasts cultured from uninvolved areas of the palm. No differences were observed in culture which could account either for the abnormal glycosaminoglycan content or the incr...

journal_title：Connective tissue research

authors： Slack C,Flint MH,Thompson BM

更新日期：1982-01-01 00:00:00

abstract：:To study the glycoproteins and transglutaminase substrates involved in healing, wounds were made in the skin of anesthetized rats with a biopsy punch. Explants made 1-5 days later were incubated with [3H]-labelled putrescine, fucose or proline. As compared with unwounded skin there was an increased incorporation of la...

journal_title：Connective tissue research

authors： Bowness JM,Henteleff H,Dolynchuk KN

更新日期：1987-01-01 00:00:00

abstract：:Abnormal polyanion metabolism in cultured fibroblasts from patients with pseudoxanthoma elasticum (PXE) was studied by incubating normal and PXE fibroblasts in culture medium containing 35SO4 for 96 hr and measuring differences in secreted 35SO4-labelled proteoglycans (35S-PG). PXE medium contained less high molecular...

journal_title：Connective tissue research

authors： Gordon SG,Overland M,Foley J

更新日期：1978-01-01 00:00:00

abstract：:The resorption of devitalized bone by isolated osteoclasts in culture was studied by scanning electron microscopy. Osteoclasts attached to the bone and resorbed mineral but left most of matrix collagen undigested in the resorption pits. Postculture-treatment of bone substrate with collagenase completely removed the ma...

journal_title：Connective tissue research

authors： Shimizu H,Sakamoto S,Sakamoto M

更新日期：1989-01-01 00:00:00

abstract：:Fras1 and the structurally related proteins Frem1, Frem2, and Frem3, comprise a novel family of extracellular matrix proteins, which localize in a similar fashion underneath the lamina densa of epithelial basement membranes. They are involved in the structural adhesion of the skin epithelium to its underlying mesenchy...

journal_title：Connective tissue research

authors： Petrou P,Makrygiannis AK,Chalepakis G

更新日期：2008-01-01 00:00:00

abstract：:Ultrasound is a therapeutic agent commonly used to treat sports-related tendinopathy. Tendon healing requires tendon cells migration to the repair site, followed by the proliferation and synthesis of extracellular matrix. This study was designed to determine the effect of ultrasound on migration of tendon cells intrin...

journal_title：Connective tissue research

authors： Tsai WC,Chen JY,Pang JH,Hsu CC,Lin MS,Chieh LW

更新日期：2008-01-01 00:00:00

abstract：:The menisci are intricately organized structures that perform many tasks in the knee. We review their structure and function and introduce new data about their tibial and femoral surfaces. As the femur and tibia approach each other when the knee is bearing load, circumferential tension develops in the menisci, enablin...

journal_title：Connective tissue research

authors： Andrews SHJ,Adesida AB,Abusara Z,Shrive NG

更新日期：2017-01-01 00:00:00

abstract：:We have previously shown in a transgenic mouse line, in which 5.2 kb of the elastin promoter was linked to the reporter enzyme chloramphenicol acetyltransferase (CAT), that the highest levels of expression were found in embryonic lungs and aorta, while lower levels were detected in other elastin-containing tissues. Fu...

journal_title：Connective tissue research

authors： Lakkakorpi J,Li K,Decker S,Korkeela E,Piddington R,Abrams W,Bashir M,Uitto J,Rosenbloom J

更新日期：1999-01-01 00:00:00

abstract：PURPOSE:Our previous study showed that partial-thickness articular cartilage defects (PTCDs) created in immature rats spontaneously healed to resemble normal hyaline cartilage, but that of mature rats did not. To identify molecules involved in the spontaneous cartilage repair observed in this model, gene expression was...

journal_title：Connective tissue research

authors： Ikegawa N,Sasho T,Yamaguchi S,Saito M,Akagi R,Muramatsu Y,Akatsu Y,Fukawa T,Nakagawa K,Nakajima A,Suzuki T,Takahashi K

更新日期：2016-05-01 00:00:00

abstract：:The present study details structural aspects of the cells of the rat intra-articular disc (IAD) of the temporomandibular joint. At the light and electron microscope level, the outline of the cells varied, although a number appeared oval/rounded. Ultrastructurally, the cells contained moderate amounts of the intracellu...

journal_title：Connective tissue research

authors： Berkovitz BK,Becker D

更新日期：2003-01-01 00:00:00

abstract：:Elastic ear cartilage and aortae from nine-day-old hamsters were incubated in Krebs-Ringer medium containing ascorbate, beta-aminopropionitrile and either [14C]proline or [3H]valine. The [14C]proline-labeled proteins were separated by chromatography on Agarose A-5 m in sodium dodecyl sulfate and their [14C]-hydroxypro...

journal_title：Connective tissue research

authors： Heeger P,Rosenbloom J

更新日期：1980-01-01 00:00:00

abstract：:An extensive literature on bone morphogenetic protein (BMP) induced generation and regeneration shows general agreement about one observation. The incidence and quantity of bone were greatest when BMP was delivered with a carrier of various biologic and non biologic polymers. In the present research, neutral lipids ei...

journal_title：Connective tissue research

authors： Urist MR,Behnam K,Kerendi F,Raskin K,Nuygen TD,Shamie AN,Malinin TI

更新日期：1997-01-01 00:00:00

abstract：:The small leucine-rich repeat proteoglycans (SLRPs) constitute a group of structurally and functionally related molecules that participate in the organization of the extracellular matrix ECM and have important effects on cell behavior. Osteosarcomas are heterogeneous bone tumors whose common characteristic is the prod...

journal_title：Connective tissue research

authors： Nikitovic D,Berdiaki K,Chalkiadaki G,Karamanos N,Tzanakakis G

更新日期：2008-01-01 00:00:00

abstract：:Of more than 2 million segmental bone defects repaired annually with bone autografts and allografts, 15-40% fail. Improving healing rates may be approached with tissue engineering and use of periosteum overlying an allograft. The present study documents gene expression in human periosteum-allograft constructs compared...

journal_title：Connective tissue research

authors： Kemppainen J,Yu Q,Alexander J,Jacquet R,Scharschmidt T,Landis W

更新日期：2014-08-01 00:00:00

abstract：PURPOSE:Treatment of meniscal injury is important for osteoarthritis (OA) prevention. Meniscus cells are divided between inner and outer cells, which have different characteristics and vascularity. We evaluated the effects of hyaluronic acid (HA) on the proliferation and migration of human inner and outer meniscus cell...

journal_title：Connective tissue research

authors： Murakami T,Otsuki S,Okamoto Y,Nakagawa K,Wakama H,Okuno N,Neo M

更新日期：2019-03-01 00:00:00

abstract：:Transforming growth factor beta-1 (TGF beta-1) is a multifunctional growth factor that is expressed in numerous cell types. It has been shown to induce secretion of dentin extracellular matrix components associated with primary dentinogenesis and to play a role in tertiary or reparative dentinogenesis. In this study, ...

journal_title：Connective tissue research

authors： Unterbrink A,O'Sullivan M,Chen S,MacDougall M

更新日期：2002-01-01 00:00:00