Degradation of five polyurethane gastric bubbles following in vivo use: SEC, ATR-IR and DSC studies.

abstract：:The Debye Function Analysis of diffraction patterns from nanosized mineral crystals showing different average degrees of maturity was carried out on engineered bone samples. The analysis relied on a bivariate family of atomistic hydroxyapatite nanocrystal models and provided information about crystal structure, size a...

journal_title：Biomaterials

authors： Guagliardi A,Cedola A,Giannini C,Ladisa M,Cervellino A,Sorrentino A,Lagomarsino S,Cancedda R,Mastrogiacomo M

更新日期：2010-11-01 00:00:00

abstract：:Given that vascular endothelial growth factor (VEGF) and placental growth factor (PIGF), over-expressed in breast cancer cells and M2-like tumor-associated macrophages (M2-TAMs) within tumor microenvironment (TME), work synergistically and independently in mediating tumor progression and immunosuppression, combinatori...

journal_title：Biomaterials

authors： Song Y,Tang C,Yin C

更新日期：2018-12-01 00:00:00

abstract：:While subcutaneous tissue has been proposed as a potential site for pancreatic islet transplantation, concern remains that the microvasculature of subcutaneous tissue is too poor to support transplanted islets. In an effort to overcome this limitation, we evaluated whether fibrin gel with human adipose-derived stem ce...

journal_title：Biomaterials

authors： Bhang SH,Jung MJ,Shin JY,La WG,Hwang YH,Kim MJ,Kim BS,Lee DY

更新日期：2013-10-01 00:00:00

abstract：:Frequent outbreaks and the rapid global spread of infectious diseases have increased the urgent need for massive vaccination especially in countries with limited resources. Intranasal vaccination facilitates the mass vaccination via needle-free delivery of vaccine through nasal mucosal surfaces. Inspired by the strong...

journal_title：Biomaterials

authors： Wang X,Yang D,Li S,Xu X,Qin CF,Tang R

更新日期：2016-11-01 00:00:00

abstract：:Reactive oxygen species (ROS) have been shown to play crucial roles in regulating various cellular functions, e.g. focal adhesion (FA) dynamics and cell migration upon growth factor stimulation. However, it is not clear how ROS are regulated at subcellular FA sites to impact cell migration. We have developed a biosens...

journal_title：Biomaterials

authors： Lin LJ,Grimme JM,Sun J,Lu S,Gai L,Cropek DM,Wang Y

更新日期：2013-05-01 00:00:00

abstract：:Current advances in skin tissue engineering and wound healing augur well for the development of split or full thickness skin substitutes to recapitulating the native functional skin. These engineered skin substitutes have fared successfully in recent years with exploration of various emerging technologies. As a result...

journal_title：Biomaterials

authors： Chouhan D,Dey N,Bhardwaj N,Mandal BB

更新日期：2019-09-01 00:00:00

abstract：:Recapitulation of the cellular microenvironment of the heart, which promotes cell contraction, remains a key challenge in cardiac tissue engineering. We report here on our work, where for the first time, a 3-dimensional (3D) spring-like fiber scaffold was fabricated, successfully mimicking the coiled perimysial fibers...

journal_title：Biomaterials

authors： Fleischer S,Feiner R,Shapira A,Ji J,Sui X,Daniel Wagner H,Dvir T

更新日期：2013-11-01 00:00:00

abstract：:Effective global control of tuberculosis (TB) is increasingly threatened by the convergence of multidrug-resistant TB and the human immunodeficiency virus (HIV) infection. TB/HIV coinfections exert a tremendous burden on the host's immune system, and this has prompted the clinical use of immunomodulators to enhance ho...

journal_title：Biomaterials

authors： Wang Y,Ke XY,Khara JS,Bahety P,Liu S,Seow SV,Yang YY,Ee PL

更新日期：2014-03-01 00:00:00

abstract：:Nanoparticles, such as dendritic polymers, are currently investigated as excellent candidates for drug delivery vehicles. In this study, we report the preparation and characterization of mPEGylated peptide dendron-doxorubicin (dendron-DOX) conjugate based vehicle carrying 14.0 wt% (weight percent) of doxorubicin (DOX)...

journal_title：Biomaterials

authors： She W,Luo K,Zhang C,Wang G,Geng Y,Li L,He B,Gu Z

更新日期：2013-02-01 00:00:00

abstract：:The differentiation of odontoblasts is initiated by the organization of differentiating ameloblasts during tooth formation. However, the exact roles of ameloblast-derived factors in odontoblast differentiation have not yet been characterized. We investigated the effects of preameloblast-conditioned medium (PA-CM) on t...

journal_title：Biomaterials

authors： Lee JH,Lee DS,Choung HW,Shon WJ,Seo BM,Lee EH,Cho JY,Park JC

更新日期：2011-12-01 00:00:00

abstract：:Translation of micelles from the laboratory to the clinic is limited by a poor understanding of their in vivo fate following administration. In this paper, we establish a robust approach to real-time monitoring of the in vivo stability of micelles using Förster Resonance Energy Transfer (FRET). This characterization m...

journal_title：Biomaterials

authors： Morton SW,Zhao X,Quadir MA,Hammond PT

更新日期：2014-04-01 00:00:00

abstract：:As double stranded, single stranded siRNA (ss-siRNA) has demonstrated gene silencing activity but still requires efficient carriers to reach its cytoplasmic target. To better understand the fundamental aspect driving the complexation of ss-siRNA with nanocarriers, the interactions between surfaces of various compositi...

journal_title：Biomaterials

authors： Giraud L,Viricel W,Leblond J,Giasson S

更新日期：2017-01-01 00:00:00

abstract：:A photografting technique to produce functional groups of silanol able to induce apatite nucleation was attempted on polyethylene substrate for biomimetic formation of bone-mineral-like apatite layer on its surface. The polyethylene surface was subjected to vapor-phase photografting of vinyltrimethoxysilane and subseq...

journal_title：Biomaterials

authors： Kim HM,Uenoyama M,Kokubo T,Minoda M,Miyamoto T,Nakamura T

更新日期：2001-09-01 00:00:00

abstract：:Regeneration of the damaged myocardium is one of the most challenging fronts in the field of tissue engineering due to the limited capacity of adult heart tissue to heal and to the mechanical and structural constraints of the cardiac tissue. In this study we demonstrate that an engineered acellular scaffold comprising...

journal_title：Biomaterials

authors： Serpooshan V,Zhao M,Metzler SA,Wei K,Shah PB,Wang A,Mahmoudi M,Malkovskiy AV,Rajadas J,Butte MJ,Bernstein D,Ruiz-Lozano P

更新日期：2013-12-01 00:00:00

abstract：:The non-specific interaction between nanoparticles (NPs) and plasma proteins occurs immediately after NPs enter the blood, resulting in the formation of the protein corona that thereafter replaces the original NPs and becomes what the organs and cells really see. Consequently, the in vivo fate of NPs and the biologica...

journal_title：Biomaterials

authors： Peng Q,Zhang S,Yang Q,Zhang T,Wei XQ,Jiang L,Zhang CL,Chen QM,Zhang ZR,Lin YF

更新日期：2013-11-01 00:00:00

abstract：:The contraction of connective tissue cells may facilitate their production and maintenance of extracellular matrix architecture and can benefit healing through wound closure. However, aberrant cell contraction can result in pathological contracture. Implants may stimulate this process leading to contracture of the sur...

journal_title：Biomaterials

authors： Menard C,Mitchell S,Spector M

更新日期：2000-09-01 00:00:00

abstract：:Highly crosslinked UHMWPEs have demonstrated improved in vitro wear properties; however, there is concern regarding loss of fracture resistance and ductility. The goals of this study were to evaluate the micromechanisms of failure under uniaxial tension and to determine the effect of gamma radiation-induced crosslinki...

journal_title：Biomaterials

authors： Gencur SJ,Rimnac CM,Kurtz SM

更新日期：2003-10-01 00:00:00

abstract：:Well-characterised human osteoblastic bone marrow cell cultures are a useful in vitro tool to analyse bone tissue/biomaterials interactions. In this work, human bone marrow was cultured in experimental conditions described to favour osteoblastic differentiation and, serially passaged cells were cultured in two widely ...

journal_title：Biomaterials

authors： Coelho MJ,Cabral AT,Fernande MH

更新日期：2000-06-01 00:00:00

abstract：:The authors aimed to develop a liquid material for embolization of aneurysms. In vitro and in vivo performances of the new embolic material were examined by cell culture and using an aneurysm model made in common carotid arteries (CCAs) of adult rats. Engineered protein ProNectin F (PnF), which contains 13 sites of an...

journal_title：Biomaterials

authors： Ohyama T,Ko IK,Miura A,Iwata H,Taki W

更新日期：2004-08-01 00:00:00

abstract：:When subjected to a monotonically increasing deformation state, the mechanical behavior of UHMWPE is characterized by a linear elastic response followed by distributed yielding and strain hardening at large deformations. During the unloading phases of an applied cyclic deformation process, the response is characterize...

journal_title：Biomaterials

authors： Bergström JS,Kurtz SM,Rimnac CM,Edidin AA

更新日期：2002-06-01 00:00:00

abstract：:Among the many applications for carbon nanotubes (CNTs), their use in medicine has drawn special attention due to their potential for a variety of therapeutic and diagnostic applications. As progress toward clinical applications continues, monitoring CNTs in vivo will be essential to evaluate their biodistribution, po...

journal_title：Biomaterials

authors： Hernández-Rivera M,Zaibaq NG,Wilson LJ

更新日期：2016-09-01 00:00:00

abstract：:We report here a thermal decomposition approach to the synthesis of water-soluble superparamagnetic manganese ferrite (MnFe(2)O(4)) nanoparticles (NPs) for magnetic resonance (MR) imaging applications. In this approach, tetraethylene glycol was utilized as a coordination and stabilization agent, rendering the NPs wate...

journal_title：Biomaterials

authors： Yang H,Zhang C,Shi X,Hu H,Du X,Fang Y,Ma Y,Wu H,Yang S

更新日期：2010-05-01 00:00:00

abstract：:Amphiphilic 4-armed star-shaped chlorin-core diblock copolymers based on methoxy poly(ethylene glycol) (mPEG) and poly (epsilon-caprolactone) (PCL) were synthesized and characterized in this study. The synthesized photosensitizer-centered amphiphilic star block copolymer that forms assembled micelle-like structures ca...

journal_title：Biomaterials

authors： Peng CL,Shieh MJ,Tsai MH,Chang CC,Lai PS

更新日期：2008-09-01 00:00:00

abstract：:Combined treatment using nonviral agent-mediated enzyme/prodrug therapy and immunotherapy had been proposed as a powerful alternative method of cancer therapy. The present study was aimed to evaluate the cytotoxicity in vitro and the therapeutic efficacy in vivo when the cytosine deaminase/5-fluorocytosine (CD/5-FC) a...

journal_title：Biomaterials

authors： Liang B,He ML,Chan CY,Chen YC,Li XP,Li Y,Zheng D,Lin MC,Kung HF,Shuai XT,Peng Y

更新日期：2009-08-01 00:00:00

abstract：:Lymphocytes typically interact with implanted biomaterials through adsorbed exogenous proteins. To provide a more complete characterization of these interactions, analysis of lymphocyte migration on adsorbed extracellular matrix proteins must accompany the commonly performed adhesion studies. We report here a comparis...

journal_title：Biomaterials

authors： Bergman AJ,Zygourakis K

更新日期：1999-12-01 00:00:00

abstract：:Immediate finishing is a highly desirable property of restorative materials. In general, the resin composites, the polyacid-modified resin composites and resin-modified glass-ionomers are finished immediately after light-curing. For the conventional glass-ionomers a waiting period of 24 h is recommended. Therefore, th...

journal_title：Biomaterials

authors： Gladys S,Braem M,Van Meerbeek B,Lambrechts P,Vanherle G

更新日期：1998-03-01 00:00:00

abstract：:A new system of single piece electrodes was applied to in vivo and in vitro measurements of anodic polarization of several alloys used in orthopaedic implants. The tested surface was scrutinized with a stereomicroscope after each experiment. This confirmed pit formation and excluded the possibility of other sudden inc...

journal_title：Biomaterials

authors： Nakayama Y,Yamamuro T,Kotoura Y,Oka M

更新日期：1989-08-01 00:00:00

abstract：:Ultrasound imaging is a widely used imaging technique. The use of contrast agents has become an indispensible part of clinical ultrasound imaging, and molecular imaging via ultrasound has recently attracted significant attention. We recently reported that "Bubble liposomes" (BLs) encapsulating US imaging gas liposomes...

journal_title：Biomaterials

authors： Negishi Y,Hamano N,Tsunoda Y,Oda Y,Choijamts B,Endo-Takahashi Y,Omata D,Suzuki R,Maruyama K,Nomizu M,Emoto M,Aramaki Y

更新日期：2013-01-01 00:00:00

abstract：:Fibrosis affects most organs, it results in replacement of normal parenchymal tissue with collagen-rich extracellular matrix, which compromises tissue architecture and ultimately causes loss of function of the affected organ. Biochemical pathways that contribute to fibrosis have been extensively studied, but the role ...

journal_title：Biomaterials

authors： Varkey M,Ding J,Tredget EE,Wound Healing Research Group.

更新日期：2014-12-01 00:00:00

abstract：:Sodium alginate hydrogel, stabilized with gelatin, is a suitable, biologically inert matrix that can be used for encapsulating and 3D bioprinting of bone-related SaOS-2 cells. However, the cells, embedded in this matrix, remain in a non-proliferating state. Here we show that addition of an overlay onto the bioprinted ...

journal_title：Biomaterials

authors： Neufurth M,Wang X,Schröder HC,Feng Q,Diehl-Seifert B,Ziebart T,Steffen R,Wang S,Müller WEG

更新日期：2014-10-01 00:00:00