Regulation of Cu,Zn-superoxide dismutase in bovine pulmonary artery endothelial cells.

abstract：:Cardiac hypertrophy is the main cause of heart failure and sudden death in patients. But the pathogenesis is unclear. Angiotensin II may contribute to cardiac hypertrophy in response to pressure overload. In angiotensin II-treated cardiomyocytes, there is a larger cross-sectional area, more apoptosis cells, and a redu...

journal_title：Journal of cellular physiology

authors： Li R,Wang X,Wu S,Wu Y,Chen H,Xin J,Li H,Lan J,Xue K,Li X,Zhuo C,He J,Tang CS,Jiang W

更新日期：2019-08-01 00:00:00

abstract：:Addition of bombesin in the presence of either forskolin or cholera toxin caused a marked (4-6 fold) enhancement of cAMP accumulation in Swiss 3T3 cells. This effect was time and concentration dependent, induced by various bombesin-like peptides and blocked by a bombesin antagonist. Enhancement of cAMP accumulation by...

journal_title：Journal of cellular physiology

authors： Millar JB,Rozengurt E

更新日期：1988-11-01 00:00:00

abstract：:A growing number of studies have suggested that long noncoding RNAs (lncRNAs) play critical roles in human malignant cancers, including hepatocellular carcinoma (HCC). However, the functions of most lncRNAs have not been elucidated in HCC. In the present study, we explored the potential functions of a novel lncRNA LOC...

journal_title：Journal of cellular physiology

authors： E C,Li C,Li H,Yang J

更新日期：2019-08-01 00:00:00

abstract：:Vitamin C is an essential micronutrient for the development of male germ cells. In the gonad, the germ cells are isolated from the systemic circulation by the blood-testis barrier, which consists of a basal layer of Sertoli cells that communicate through an extensive array of tight junction complexes. To study the beh...

journal_title：Journal of cellular physiology

authors： Angulo C,Castro MA,Rivas CI,Segretain D,Maldonado R,Yañez AJ,Slebe JC,Vera JC,Concha II

更新日期：2008-12-01 00:00:00

abstract：:Isolated hamster intestinal epithelial cells can be separated by velocity sedimentationion on 2-10% Ficoll gradients into three subpopulations of cells which differ in morphology, biochemistry, physiology, and membrane components. These subpopulations are not pure but are enriched in a single cell type to the extent t...

journal_title：Journal of cellular physiology

authors： Carter JH,Poretz RD,Eichholz A

更新日期：1982-04-01 00:00:00

abstract：:The temperature sensitive leucyl-tRNA synthetase mutant tsHl and two revertants have been compared to the parental Chinese hamster ovary cells with respect to the effects of amino acid concentrations in the medium on growth. Elevating the leucine concentration 30- or 100-fold allowed tsHl to grow exponentially at 38.5...

journal_title：Journal of cellular physiology

authors： Molnar SJ,Rauth AM

更新日期：1979-02-01 00:00:00

abstract：:MiR-137 has been identified as potential hepatocellular carcinoma (HCC) prognostic biomarkers. Highly relevant HCC prognostic biomarkers may be derived from combinations of miR-137 with its target genes involved in the regulation of liver microenvironment. This study aimed at the discovery of such a combination with i...

journal_title：Journal of cellular physiology

authors： Wei Q,Zhao L,Jiang L,Bi J,Yu Z,Zhao L,Song X,Sun M,Chen Y,Wei M

更新日期：2019-07-01 00:00:00

abstract：:Lung cancer (LC) is the leading cause of cancer-related deaths all over the world, among both men and women, with an incidence of over 200,000 new cases per year coupled with a very high mortality rate. LC comprises of two major clinicopathological categories: small-cell (SCLC) and nonsmall-cell lung carcinoma (NSCLC)...

journal_title：Journal of cellular physiology

authors： Uddin A,Chakraborty S

更新日期：2018-04-20 00:00:00

abstract：:Baclofen is used clinically as a drug that treats spasticity, which is a syndrome characterized by excessive contraction of the muscles and hyperflexia in the central nervous system (CNS), by activating GABA(B) receptors (GABA(B)Rs). Baclofen was recently reported to desensitize chemokine receptors and to suppress inf...

journal_title：Journal of cellular physiology

authors： Huang S,Mao J,Wei B,Pei G

更新日期：2015-07-01 00:00:00

abstract：:During the development of atherosclerotic and fibromuscular proliferates/lesions, smooth muscle cells (SMC) in the media, particularly near the lumen, are activated to migrate into the intima, where they continue to proliferate to form an intimal thickening. It is to date unclear whether SMCs situated adjacent to the ...

journal_title：Journal of cellular physiology

authors： Betz E,Fallier-Becker P,Wolburg-Buchholz K,Fotev Z

更新日期：1991-06-01 00:00:00

abstract：:We investigated the role of mammalian target of rapamycin/nuclear factor-kappa B (mTOR/NF-κB) signaling pathway in high thoracic epidural anesthesia (HTEA) against myocardial ischemia-reperfusion (I/R) injury in rats. The rat model of myocardial I/R injury was established. Ninety rats were divided into the normal, sha...

journal_title：Journal of cellular physiology

authors： Huang WQ,Wen JL,Lin RQ,Wei P,Huang F

更新日期：2018-09-01 00:00:00

abstract：:The presence of inflammatory cells and their products in the tumor microenvironment plays a crucial role in the pathogenesis of a tumor. Releasing the cytokines from a host in response to infection and inflammation can inhibit tumor growth and progression. However, tumor cells can also respond to the host cytokines wi...

journal_title：Journal of cellular physiology

authors： Shadpour P,Zamani M,Aghaalikhani N,Rashtchizadeh N

更新日期：2019-02-18 00:00:00

abstract：:The plasma level of the regulatory metabolite adenosine increases during the activation of coagulation and inflammation. Here we investigated the effect of adenosine on modulation of thrombin-mediated proinflammatory responses in HUVECs. We found that adenosine inhibits the barrier-disruptive effect of thrombin in HUV...

journal_title：Journal of cellular physiology

authors： Hassanian SM,Dinarvand P,Rezaie AR

更新日期：2014-09-01 00:00:00

abstract：:The influence upon different cellular and humoral parameters of hemopoiesis of three structurally unrelated, highly purified bacterial cell-wall components (BCWC) was investigated. The spleens of C57BL/6 mice assayed 6 days after the injection of either lipid A or outer-membrane lipoportein, but not murein, showed a m...

journal_title：Journal of cellular physiology

authors： Staber FG,Johnson GR

更新日期：1980-10-01 00:00:00

abstract：:We report here that heptanol (3.5 mM) induces in vitro a rapid formation of smooth endoplasmic reticulum aggregates (SERA) within isolated islets of Langerhans. SERA appeared after only 15 min of exposure to the alkanol and increased in number during the first 30 min of incubation. At that time, SERA represented 2% an...

journal_title：Journal of cellular physiology

authors： Knodel S,Meda P,Orci L

更新日期：1987-10-01 00:00:00

abstract：:Previous studies demonstrated that overexpression of the type-1 insulin-like growth factor (IGF) receptor (IGF-1R) in skeletal myogenic cell lines increased proliferation and differentiation responses to IGF. However, it was unclear if such manipulations in primary, untransformed skeletal myogenic cells would result i...

journal_title：Journal of cellular physiology

authors： Quinn LS,Haugk KL

更新日期：1996-07-01 00:00:00

abstract：:The hexose transport system of undifferentiated L6 rat myoblasts was investigated. 2-Deoxy-D-glucose (2-DOG) and 2-deoxy-2-fluoro-D-glucose (2FG) were used as analogues to investigate the rate-limiting step of hexose uptake into the cell. Virtually all of the 2-DOG or 2FG taken up into the cell was found to be in the ...

journal_title：Journal of cellular physiology

authors： D'Amore T,Lo TC

更新日期：1986-04-01 00:00:00

abstract：:The main aim of this investigation was to determine whether a functional relationship existed between epidermal growth factor (EGF) and voltage-gated sodium channel (VGSC) upregulation, both associated with strongly metastatic prostate cancer cells. Incubation with EGF for 24 h more than doubled VGSC current density. ...

journal_title：Journal of cellular physiology

authors： Ding Y,Brackenbury WJ,Onganer PU,Montano X,Porter LM,Bates LF,Djamgoz MB

更新日期：2008-04-01 00:00:00

abstract：:During embryonic and early postnatal development, the chick leg muscle cells undergo a series of changes in their electrical responses in the following sequence: passive response, plateau response, plateau plus spike response and spike response. This suggests that the electrogenetic mechanism of muscles matures during...

journal_title：Journal of cellular physiology

authors： Kano M

更新日期：1975-12-01 00:00:00

abstract：:Cells isolated from fetal rat calvaria (RC) and maintained in vitro in medium containing ascorbic acid and B-glycerophosphate form three-dimensional, mineralized nodules having the histological, immunohistological, and ultrastructural characteristics of woven bone. We have studied the effects of forskolin (FSK), a dit...

journal_title：Journal of cellular physiology

authors： Turksen K,Grigoriadis AE,Heersche JN,Aubin JE

更新日期：1990-01-01 00:00:00

abstract：:Measurements made on contraction latencies in Spirostomun suggest that mechanical stimulation causes contractions to be initiated by the release of small amounts of calcium from a store tightly coupled to the contractile apparatus. Contraction to electrical stimulation appears to result from the gross electrophoretic ...

journal_title：Journal of cellular physiology

authors： Hamilton TC,Osborn D

更新日期：1977-06-01 00:00:00

abstract：:This study examines the regulation of Swarm rat chondrosarcoma (SRC) cell proliferation in vitro. In serum-free cultures, SRC cells showed only transient DNA synthesis and this was increased by serum. Transforming growth factor-beta (TGF-beta) was identified as an essential serum component, since the mitogenic effect ...

journal_title：Journal of cellular physiology

authors： Guerne PA,Lotz M

更新日期：1991-10-01 00:00:00

abstract：:Diabetic nephropathy (DN) is one of the most serious and dangerous chronic complications caused by diabetes mellitus, and the identification and development of novel biomarkers could be beneficial for the diagnosis and prognosis of DN patients. This study focused on researching the differently expressed pattern of the...

journal_title：Journal of cellular physiology

authors： Song X,Gong M,Chen Y,Liu H,Zhang J

更新日期：2019-02-01 00:00:00

abstract：:The predominant cyclooxygenase products of keratinocytes are prostaglandin (PG)E2 and PGF2 alpha with only trace amounts of PGI2 synthesis detected. When normal or immortal (NM1) keratinocytes were co-cultured with mitomycin C-treated 3T3 cells, increased synthesis of PGI2 was noted compared to mitomycin C-treated 3T3...

journal_title：Journal of cellular physiology

authors： Baden HP,Goldaber ML,Kvedar JC

更新日期：1992-02-01 00:00:00

abstract：:Glucose and tumor necrosis factor-alpha (TNFalpha) concentrations are elevated in diabetes. Both of these factors correlate with diabetic vasculopathy and endothelial cell apoptosis, yet their combined effects have not been measured. We have previously shown that the angiogenic growth factor fibroblast growth factor-2...

journal_title：Journal of cellular physiology

authors： Clyne AM,Zhu H,Edelman ER

更新日期：2008-10-01 00:00:00

abstract：:The role of microtubules in mitogen-induced human lymphocyte activation and proliferation was examined. The effect of colchicine, a microtubule-disrupting agent, was compared with taxol, a microtubule-stabilizing drug, and with isaxonine (N-isopropyl-amino-2-pyrimidine orthophosphate), a proposed microtubular-active d...

journal_title：Journal of cellular physiology

authors： Cuthbert JA,Shay JW

更新日期：1983-08-01 00:00:00

abstract：:The nuclear lamina is a fibrous structure at the nucleoplasmic surface of the inner nuclear membrane. Its assembly state is regulated by phosphorylation of its protein components, the lamins A, B, and C. The isoprenylation of the lamins is essential for their proper membrane anchoring and functionality. The content an...

journal_title：Journal of cellular physiology

authors： Bruscalupi G,Di Croce L,Lamartina S,Zaccaria ML,Luzzatto AC,Trentalance A

更新日期：1997-05-01 00:00:00

abstract：:Previous studies from our laboratory have shown that Chinese hamster V79 cells mutated to high level resistance to amphotericin B have a lower cellular level of cholesterol, the target molecule for the polyene antibiotic. Two amphotericin B-resistant (AMBR) mutants were each hybridized to their parental amphotericin B...

journal_title：Journal of cellular physiology

authors： Hidaka K,Akiyama SI,Kuwano M

更新日期：1981-01-01 00:00:00

abstract：:Asthma is the most common respiratory disease accompanied by lung inflammatory disorders. The main symptoms are airway obstruction, chronic inflammation due to mast cell and eosinophil activity, and the disturbance of immune responses mostly mediated by the Th2 response. Genetic background and environmental factors al...

journal_title：Journal of cellular physiology

authors： Mousavi SR,Ahmadi A,Jamalkandi SA,Salimian J

更新日期：2019-12-01 00:00:00

abstract：:The p53 protein directly regulates the expression of the WAF1 (wild-type p53-activated fragment 1) protein which is a cyclin-dependent kinase inhibitor (CDK1). DNA damaging agents such as ionizing or UV radiation, and some chemical agents induce WAF1 in wild-type p53 containing cells, thereby halting cell cycle progre...

journal_title：Journal of cellular physiology

authors： Shiohara M,Akashi M,Gombart AF,Yang R,Koeffler HP

更新日期：1996-03-01 00:00:00