Nuclear lamina assembly in the first cell cycle of rat liver regeneration.

abstract：:Leukocyte accumulation has been shown to be increased in sepsis. Moreover, in inducible nitric oxide synthase (iNOS) knockout mice, a further increase in leukocyte accumulation has been observed during sepsis, suggesting that nitric oxide (NO) may affect leukocyte/endothelial interaction. Accelerated peroxynitrite for...

journal_title：Journal of cellular physiology

authors： Lelamali K,Wang W,Gengaro P,Edelstein C,Schrier RW

更新日期：2001-09-01 00:00:00

abstract：:Bone morphogenetic protein-2 (BMP-2), a member of transforming growth factor-beta superfamily, plays a crucial role in migration and metastasis of human cancer cells. Integrins are the major adhesive molecules in mammalian cells. Here we found that BMP-2 directed the migration and increased cell surface and mRNA expre...

journal_title：Journal of cellular physiology

authors： Fong YC,Li TM,Wu CM,Hsu SF,Kao ST,Chen RJ,Lin CC,Liu SC,Wu CL,Tang CH

更新日期：2008-12-01 00:00:00

abstract：:To clarify the manner by which erythropoietin (EP), stem cell factor (SCF), or insulin-like growth factor I (IGF-I) regulate erythropoiesis, apoptosis of human erythroid progenitor cells was investigated. Human burst-forming units-erythroid (BFU-E) partially purified from peripheral blood were cultured for 6 days to g...

journal_title：Journal of cellular physiology

authors： Muta K,Krantz SB

更新日期：1993-08-01 00:00:00

abstract：:Interleukin (IL)-18 is a pro-inflammatory cytokine belonging to the IL-1 family, first identified for its interferon-γ-inducing properties. IL-18 regulates both T helper (Th) 1 and Th2 responses. It acts synergistically with IL-12 in the Th1 paradigm, whereas with IL-2 and without IL-12 it can induce Th2 cytokine prod...

journal_title：Journal of cellular physiology

authors： Vecchié A,Bonaventura A,Toldo S,Dagna L,Dinarello CA,Abbate A

更新日期：2021-03-01 00:00:00

abstract：:Activated hepatic stellate cells promote hepatocellular carcinoma (HCC) progression. Hepatic stellate cells play a key role in retinoid metabolism, and activation of stellate cells increases retinoic acid (RA) in the liver. However, the role of RA in HCC proliferation remains unclear. We aimed to analyse the mechanism...

journal_title：Journal of cellular physiology

authors： Lin HH,Peng YJ,Tsai MJ,Wu YY,Tsai TN,Huang HH,Shih YL,Chang WK,Hsieh TY

更新日期：2020-02-01 00:00:00

abstract：:Arsenicosis induced by chronic exposure to arsenic is recognized as one of the main damaging effects on public health. Exposure to arsenic can cause hepatic fibrosis, but the molecular mechanisms by which this occurs are complex and elusive. It is not known if miRNAs are involved in arsenic-induced liver fibrosis. We ...

journal_title：Journal of cellular physiology

authors： Xue J,Xiao T,Wei S,Sun J,Zou Z,Shi M,Sun Q,Dai X,Wu L,Li J,Xia H,Tang H,Zhang A,Liu Q

更新日期：2021-01-22 00:00:00

abstract：:Inhibition of insulin-induced 3T3-L1 preadipocyte differentiation by rapamycin has been attributed to a blockade of the early critical clonal expansion phase of the adipogenic program. Rapamycin binds to, and inhibits, mTOR (mammalian target of rapamycin), leading to diminution of p70 S6 kinase activity and eukaryotic...

journal_title：Journal of cellular physiology

authors： Gagnon A,Lau S,Sorisky A

更新日期：2001-10-01 00:00:00

abstract：:During interphase, the centrosome concentrates cell stress response molecules, including chaperones and proteasomes, into a proteolytic center. However, whether the centrosome functions as proteolytic center during mitosis is not known. In this study, cultured mammalian cells were treated with the proteasome inhibitor...

journal_title：Journal of cellular physiology

authors： Ehrhardt AG,Sluder G

更新日期：2005-09-01 00:00:00

abstract：:The growth of human epithelial cells is stimulated by cholera toxin and analogues of cyclic AMP, while the growth of breast derived fibroblasts is inhibited. These compounds have little effect on DNA synthesis in the absence of other mitogens but show a synergistic effect with serum and/or EGF. The results suggest tha...

journal_title：Journal of cellular physiology

authors： Taylor-Papadimitriou J,Purkis P,Fentiman IS

更新日期：1980-03-01 00:00:00

abstract：:An isoform of the Na(+)/Ca(2+) exchanger (SDNCX1.10) was cloned from mesangial cells of Sprague-Dawley rat. Regulation of this isoform was compared to two other clones that were derived from the Dahl/Rapp salt sensitive (SNCX) and salt resistant rat (RNCX). All isoforms differ at the alternative splice site and at ami...

journal_title：Journal of cellular physiology

authors： Williams I,Williams C,Siroky B,Bates E,Kovacs G,Peti-Peterdi J,Unlap MT,Bell PD

更新日期：2004-05-01 00:00:00

abstract：:Endothelial cell-derived growth factor (ECDGF) is a soluble mitogen secreted in vitro by bovine aortic endothelium. ECDGF is a mixture of at least two distinct heat-stable and trypsin-sensitive mitogens. Large amounts of mitogenic activity were found in lysates prepared from cultured endothelial cells. Other nonmitoge...

journal_title：Journal of cellular physiology

authors： Gajdusek CM,Schwartz SM

更新日期：1984-11-01 00:00:00

abstract：:Cells of rat parotid glands were maximally stimulated to initiate DNA synthesis by injecting into the animal a single dose of 25 to 150 mg of isoproterenol/kg of body weight. During the 18- to 21-hr prereplicative period following injection of the highest dose of the drug, there were two predominant and transient redi...

journal_title：Journal of cellular physiology

authors： Campos Gonzales R,Whitfield JF,Boynton AL,MacManus JP,Rixon RH

更新日期：1984-03-01 00:00:00

abstract：:The carboxyl-terminal domain (CTD) of the largest subunit of mammalian RNA polymerase II (RNAP II) consists of 52 repeats of a consensus heptapeptide and is subject to phosphorylation and dephosphorylation events during each round of transcription. RNAP II activity is regulated during the cell cycle and cell cycle-dep...

journal_title：Journal of cellular physiology

authors： Oelgeschläger T

更新日期：2002-02-01 00:00:00

abstract：:Infection with Verotoxin producing Escherichia coli (VTEC) has been implicated in hemolytic uremic syndrome, the leading cause of pediatric renal failure. Verotoxin (VT) binds to globotriaosylceramide (Gal alpha 1-4Gal beta 1-4GlcCer Gb3) in susceptible cells. Gb3 is required for cytotoxicity and toxin-resistant cells...

journal_title：Journal of cellular physiology

authors： Pudymaitis A,Lingwood CA

更新日期：1992-03-01 00:00:00

abstract：:Mammalian erythrocytes are highly specialized cells that have adapted to lose their nuclei and cellular components during maturation to ensure oxygen delivery. Nuclear extrusion, the most critical event during erythropoiesis, represents an extreme case of asymmetric partitioning that requires a dramatic reorganization...

journal_title：Journal of cellular physiology

authors： Xie S,Yan B,Feng J,Wu Y,He N,Sun L,Zhou J,Li D,Liu M

更新日期：2019-11-01 00:00:00

abstract：:An association has been proved between high salt consumption and cardiovascular mortality. In vertebrates, the heart is the first functional organ to be formed. However, it is not clear whether high-salt exposure has an adverse impact on cardiogenesis. Here we report high-salt exposure inhibited basement membrane brea...

journal_title：Journal of cellular physiology

authors： Gao LR,Wang G,Zhang J,Li S,Chuai M,Bao Y,Hocher B,Yang X

更新日期：2018-09-01 00:00:00

abstract：:The phytohemagglutinin (PHA)-stimulated human lymphocytes demonstrated trace or no activity (dihydro) folate acid reductase using three methods including a radioassay, but demonstrated ample activity of thymidylate synthetase. This was true regardless of the day of harvest, (first through seventh) of the stimulated ly...

journal_title：Journal of cellular physiology

authors： Haurani FI,Kardinal CG,Biermann WA

更新日期：1978-04-01 00:00:00

abstract：:Sevoflurane has been commonly utilized in nonobstetric surgeries in pregnant women, and its impacts on fetal brain are still not completely known. Ectopic NR4A2 expression has been reported to be related with familial Parkinson disease, and through dual luciferase we found that NR4A2 is a target gene of microRNA-183 (...

journal_title：Journal of cellular physiology

authors： Shao CZ,Xia KP

更新日期：2019-04-01 00:00:00

abstract：:Several studies have shown that interleukin-4 (IL-4) down-regulates synthesis of prostaglandin E2 (PGE2). We evaluated the mechanisms for this suppression in human alveolar macrophages (HAMs). Normal HAMs were obtained from healthy nonsmoking volunteers. The cells either remained unstimulated, or were exposed to 10 mi...

journal_title：Journal of cellular physiology

authors： Yano T,Hopkins HA,Hempel SL,Monick M,Hunninghake GW

更新日期：1995-10-01 00:00:00

abstract：BACKGROUND:Cigarette smoke exposure, increasing Toll-like receptor 4 (TLR4) and reactive oxygen species (ROS), promotes inflammatory responses in airway epithelial cells. Chronic inflammation, microRNA (miRNA), and oxidative stress are associated with cancer development. AIMS:The present study was aimed to explore whe...

journal_title：Journal of cellular physiology

authors： Pace E,Di Vincenzo S,Di Salvo E,Genovese S,Dino P,Sangiorgi C,Ferraro M,Gangemi S

更新日期：2019-12-01 00:00:00

abstract：:A mouse mammary epithelial cell line, NMuMG, exhibits a low capacity to grow in semisolid medium as colonies and it is not tumorigenic in nude mice. In contrast, NMuMG cells which have been transformed by an activated c-Harvey ras proto-oncogene, NMuMG/rasH, or by the polyoma middle T-transforming gene, NMuMG/pyt, are...

journal_title：Journal of cellular physiology

authors： Salomon DS,Perroteau I,Kidwell WR,Tam J,Derynck R

更新日期：1987-03-01 00:00:00

abstract：:The transforming growth factor-beta (TGF-beta) superfamily includes more than 30 members which have a broad array of biological activities. TGF-beta superfamily ligands bind to type II and type I serine/threonine kinase receptors and transduce signals via Smad proteins. Receptor-regulated Smads (R-Smads) can be classi...

journal_title：Journal of cellular physiology

authors： Miyazono K,Kusanagi K,Inoue H

更新日期：2001-06-01 00:00:00

abstract：:Secretory leukocyte protease inhibitor (SLPI) is a serine protease inhibitor that was related to cancer development and metastasis dissemination on several types of tumors. However, it is not known the effect of SLPI on mammary and colon tumors. The aim of this study was to examine the effect of SLPI on mammary and co...

journal_title：Journal of cellular physiology

authors： Amiano NO,Costa MJ,Reiteri RM,Payés C,Guerrieri D,Tateosian NL,Sánchez ML,Maffia PC,Diament M,Karas R,Orqueda A,Rizzo M,Alaniz L,Mazzolini G,Klein S,Sallenave JM,Chuluyan HE

更新日期：2013-02-01 00:00:00

abstract：:Human skin fibroblasts contracted fibrin gels in a time- and cell-dependent manner. Under optimal conditions, gel contraction amounted to more than 50% in 2 hr. Fibronectin did not promote contraction, and fibrinolysis was not required for contraction, although gels contracted without serum or aprotinin were lysed. Be...

journal_title：Journal of cellular physiology

authors： Tuan TL,Grinnell F

更新日期：1989-09-01 00:00:00

abstract：:The p53 protein directly regulates the expression of the WAF1 (wild-type p53-activated fragment 1) protein which is a cyclin-dependent kinase inhibitor (CDK1). DNA damaging agents such as ionizing or UV radiation, and some chemical agents induce WAF1 in wild-type p53 containing cells, thereby halting cell cycle progre...

journal_title：Journal of cellular physiology

authors： Shiohara M,Akashi M,Gombart AF,Yang R,Koeffler HP

更新日期：1996-03-01 00:00:00

abstract：:The clinical literature strongly suggests that bone healing in cigarette smokers is impaired. Since cigarette smoke (CS) contains numerous polycyclic aromatic hydrocarbons (PAHs), and since dioxins impair bone formation in vivo via the Aryl Hydrocarbon Receptor (AHR), we investigated the impact of PAH/AHR signaling on...

journal_title：Journal of cellular physiology

authors： Kung MH,Yukata K,O'Keefe RJ,Zuscik MJ

更新日期：2012-03-01 00:00:00

abstract：:Damage-associated molecular patterns, including mitochondrial DNA (mtDNA) are released during hemorrhage resulting in the development of endotheliopathy. Tranexamic acid (TXA), an antifibrinolytic drug used in hemorrhaging patients, enhances their survival despite the lack of a comprehensive understanding of its cellu...

journal_title：Journal of cellular physiology

authors： Prudovsky I,Carter D,Kacer D,Palmeri M,Soul T,Kumpel C,Pyburn K,Barrett K,DeMambro V,Alexandrov I,Brandina I,Kramer R,Rappold J

更新日期：2019-11-01 00:00:00

abstract：:Two transport systems for neutral amino acids have been characterised in LLC-PK, cells. The first, which transports alanine in a sodium-dependent manner, also mediates alanine exchange and is perferentially inhibited by serine, cysteine, and alpha-amino-n-butyric acid. This system resembles the ASC system in Ehrlich a...

journal_title：Journal of cellular physiology

authors： Sepúlveda FV,Pearson JD

更新日期：1982-08-01 00:00:00

abstract：:Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken int...

journal_title：Journal of cellular physiology

authors： Caligiuri I,Rizzolio F,Boffo S,Giordano A,Toffoli G

更新日期：2012-08-01 00:00:00

abstract：:A human osteosarcoma cell line, U-2 OS, cultured under serum-free conditions, was shown to produce a growth factor (osteosarcoma-derived growth factor, ODGF) for human-cultured glial cells, fibroblasts, and other cells. ODGF, collected from the spent medium of 2 OS cultures, was purified by a sequence involving hepari...

journal_title：Journal of cellular physiology

authors： Heldin CH,Westermark B,Wasteson A

更新日期：1980-11-01 00:00:00