Hormonal and nutritional factors influencing glycogen deposition in primary cultures of rat liver parenchymal cells.

abstract：:The human cervical cancer (CC) has been identified as one of the most common tumors in women, and the molecular regulation in CC still remains unclear. The dysregulation of periostin has been found in a variety of cancers, but whether it is involved in the regulation of CC is unknown. The present study aimed to invest...

journal_title：Journal of cellular physiology

authors： Han X,Wang Q,Wang Y,Hu B,Dong X,Zhang H,Wang W

更新日期：2019-08-01 00:00:00

abstract：:Exposure of live cells to shear flow induces major changes in cell shape, adhesion to the extracellular matrix, and migration. In the present study, we show that exposure of cultured multiple myeloma (MM) cells to shear flow of 4-36 dynes/cm(2) triggers the extension of long tubular protrusions (denoted flow-induced p...

journal_title：Journal of cellular physiology

authors： Porat Z,Yaron I,Katz BZ,Kam Z,Geiger B

更新日期：2011-12-01 00:00:00

abstract：:Deep vein thrombosis associated with advanced cancer is known as Trousseau's syndrome. We hypothesized that thrombin, an activator of protease-activated receptor (PAR)-1 and PAR-4 contributes to tumor metastasis. In this study, we demonstrated that thrombin and the PAR-1 activating peptide (AP) SFLLRN, but not the PAR...

journal_title：Journal of cellular physiology

authors： Chang LH,Chen CH,Huang DY,Pai HC,Pan SL,Teng CM

更新日期：2011-04-01 00:00:00

abstract：:The effects of P2Y2 purinoceptor activation on c-Fos expression and the signaling pathways evoked by extracellular ATP/UTP in HeLa cells were investigated. We found that P2Y2 activation induced c-Fos protein and phosphorylated the extracellular signal-regulated kinases 1 and 2 (ERK1/2). The P2Y2-stimulated c-Fos induc...

journal_title：Journal of cellular physiology

authors： Muscella A,Elia MG,Greco S,Storelli C,Marsigliante S

更新日期：2003-05-01 00:00:00

abstract：:Norepinephrine (NE) produced a dose-dependent inhibition of 125I-epidermal growth factor (EGF) binding to adult rat hepatocytes in primary culture. This effect was maximal after 1 hr of incubation with NE and could be blocked by the presence of an alpha 1-specific adrenergic receptor antagonist. The inhibition of bind...

journal_title：Journal of cellular physiology

authors： Cruise JL,Cotecchia S,Michalopoulos G

更新日期：1986-04-01 00:00:00

abstract：:Glutamine is the most abundant free amino acid in the body and is known to play a regulatory role in several cell specific processes including metabolism (e.g., oxidative fuel, gluconeogenic precursor, and lipogenic precursor), cell integrity (apoptosis, cell proliferation), protein synthesis, and degradation, contrac...

journal_title：Journal of cellular physiology

authors： Curi R,Lagranha CJ,Doi SQ,Sellitti DF,Procopio J,Pithon-Curi TC,Corless M,Newsholme P

更新日期：2005-08-01 00:00:00

abstract：:Leukemia inhibitory factor (LIF) and its receptor (LIFR) are "twins" of Oncostatin M (OSM) and OSMR, respectively, likely having arisen through gene duplications. We compared their effects in a bone nodule-forming model of in vitro osteogenesis, rat calvaria (RC) cell cultures. Using a dominant-negative LIF mutant (hL...

journal_title：Journal of cellular physiology

authors： Malaval L,Liu F,Vernallis AB,Aubin JE

更新日期：2005-08-01 00:00:00

abstract：:Autophagy is a crucial cellular homeostatic process and an important part of the host defense system. Dysfunction in autophagy enhances tissue susceptibility to infection and multiple diseases. However, the role of nucleotide oligomerization domain 1 (NOD1) in autophagy in bovine hepatocytes is not well known. Therefo...

journal_title：Journal of cellular physiology

authors： Roy AC,Chang G,Roy S,Ma N,Gao Q,Shen X

更新日期：2020-12-24 00:00:00

abstract：:HeLa (substrain Ho) grown in serum free medium showed an increase in the specific activity of alkaline phosphatase when fetal calf serum (10%) was added to the medium (9.7 nmoles/sec/mg protein to 86.8). Under the same conditions, eight intracellular enzymes showed no increase in activity. Similar results were obtaine...

journal_title：Journal of cellular physiology

authors： Carlson CW

更新日期：1979-01-01 00:00:00

abstract：:During the development of atherosclerotic and fibromuscular proliferates/lesions, smooth muscle cells (SMC) in the media, particularly near the lumen, are activated to migrate into the intima, where they continue to proliferate to form an intimal thickening. It is to date unclear whether SMCs situated adjacent to the ...

journal_title：Journal of cellular physiology

authors： Betz E,Fallier-Becker P,Wolburg-Buchholz K,Fotev Z

更新日期：1991-06-01 00:00:00

abstract：:Modeling breast cancer in the mouse has helped to better define the heterogeneity of human breast cancer. In the recent past, it has become evident that some limitations have restricted the potential benefits that can be achieved with this approach. In this review, we highlight some key points that should be taken int...

journal_title：Journal of cellular physiology

authors： Caligiuri I,Rizzolio F,Boffo S,Giordano A,Toffoli G

更新日期：2012-08-01 00:00:00

abstract：:Mammalian sperm require to spend a limited period of time in the female reproductive tract to become competent to fertilize in a process called capacitation. It is well established that HCO3- is essential for capacitation because it activates the atypical soluble adenylate cyclase ADCY10 leading to cAMP production, an...

journal_title：Journal of cellular physiology

authors： Puga Molina LC,Pinto NA,Torres Rodríguez P,Romarowski A,Vicens Sanchez A,Visconti PE,Darszon A,Treviño CL,Buffone MG

更新日期：2017-06-01 00:00:00

abstract：:Cancer cell lines have contributed immensely in understanding the complex physiology of cancers. They are excellent material for studies as they offer homogenous samples without individual variations and can be utilised with ease and flexibility. Also, the number of assays and end-points one can study is almost limitl...

journal_title：Journal of cellular physiology

authors： Ravi M,Ramesh A,Pattabhi A

更新日期：2017-10-01 00:00:00

abstract：:The role of microtubules in mitogen-induced human lymphocyte activation and proliferation was examined. The effect of colchicine, a microtubule-disrupting agent, was compared with taxol, a microtubule-stabilizing drug, and with isaxonine (N-isopropyl-amino-2-pyrimidine orthophosphate), a proposed microtubular-active d...

journal_title：Journal of cellular physiology

authors： Cuthbert JA,Shay JW

更新日期：1983-08-01 00:00:00

abstract：:Impaired cardiac control of intracellular diastolic Ca(2+) gives rise to arrhythmias. Whereas exercise training corrects abnormal cyclic Ca(2+) handling in heart failure, the effect on diastolic Ca(2+) remains unstudied. Here, we studied the effect of exercise training on the generation and propagation of spontaneous ...

journal_title：Journal of cellular physiology

authors： Kemi OJ,MacQuaide N,Hoydal MA,Ellingsen O,Smith GL,Wisloff U

更新日期：2012-01-01 00:00:00

abstract：:In this review, we focused our attention on the more important natural extracellular matrix (ECM) molecules (collagen and fibrin), employed as cellular scaffolds for tissue engineering and on a class of semi-synthetic materials made from the fusion of specific oligopeptide sequences, showing biological activities, wit...

journal_title：Journal of cellular physiology

authors： Rosso F,Marino G,Giordano A,Barbarisi M,Parmeggiani D,Barbarisi A

更新日期：2005-06-01 00:00:00

abstract：:Protein kinase C and mitogen-activated protein (MAP) kinase are expressed in all smooth muscle cells and believed to be important in several physiologically relevant properties of this muscle. Our goal was to determine if protein kinase C and MAP kinase are activated by a simple increase in cellular Ca(2+) and to dete...

journal_title：Journal of cellular physiology

authors： Katoch SS,Su X,Moreland RS

更新日期：1999-05-01 00:00:00

abstract：:The presence of inflammatory cells and their products in the tumor microenvironment plays a crucial role in the pathogenesis of a tumor. Releasing the cytokines from a host in response to infection and inflammation can inhibit tumor growth and progression. However, tumor cells can also respond to the host cytokines wi...

journal_title：Journal of cellular physiology

authors： Shadpour P,Zamani M,Aghaalikhani N,Rashtchizadeh N

更新日期：2019-02-18 00:00:00

abstract：:This review addresses peptide regions of human tumor liberated protein (TLP) complexes with antigenic activity. The review also deals with antibodies reacting with such proteins, to be used for diagnostic and clinical purposes. We identified peptide sequences of the TLP 100 kDa protein. Lung cancer cells were found po...

journal_title：Journal of cellular physiology

authors： Tarro G

更新日期：2009-10-01 00:00:00

abstract：:Regulation of P-glycoprotein (Pgp) expression occurs not only at the DNA and mRNA level but also at the protein level. We showed previously that Pgp was stabilized when multidrug-resistant CH(R)C5 and SKVCR 2.0 ovarian cell lines were subjected to serum-starved or high-cell-density growth conditions, whereas Pgp turno...

journal_title：Journal of cellular physiology

authors： Zhang W,Ling V

更新日期：2000-07-01 00:00:00

abstract：:Type IV collagenases are secreted as latent 92 and 72 kDa proenzymes which are then activated extracellularly. The mechanisms by which they are activated in vivo are not clear. We have studied the activation of porcine endothelial cell type IV collagenases by tissue and plasma kallikrein, and found that tissue kallikr...

journal_title：Journal of cellular physiology

authors： Desrivières S,Lu H,Peyri N,Soria C,Legrand Y,Ménashi S

更新日期：1993-12-01 00:00:00

abstract：:Incubation of alveolar macrophages or hepatocytes in media in which Na+ is replaced by K+ ("isotonic-K buffer") inhibited the movement of internalized ligand from late endosomes to lysosomes (Ward et al.: Journal of Cell Biology 110:1013-1022, 1990). In this study we investigate the mechanism responsible for the isoto...

journal_title：Journal of cellular physiology

authors： Ward DM,Hackenyos DP,Davis-Kaplan S,Kaplan J

更新日期：1990-12-01 00:00:00

abstract：:Resistin, firstly reported as an adipocyte-specific hormone, is suggested to be an important link between obesity and diabetes. Recent studies have suggested an association between resistin and atherogenic processes. The adhesion of circulating monocytes to endothelial cells is a critical step in the early stages of a...

journal_title：Journal of cellular physiology

authors： Hsu WY,Chao YW,Tsai YL,Lien CC,Chang CF,Deng MC,Ho LT,Kwok CF,Juan CC

更新日期：2011-08-01 00:00:00

abstract：:Active oxygen species are generated in cells during pathophysiologic conditions such as inflammation and postischemic reperfusion. If oxygen radical scavengers are added before reperfusion, then the magnitude of injury is reduced. We investigated whether free radicals generated following exposure to hypoxia and reoxyg...

journal_title：Journal of cellular physiology

authors： Koong AC,Giaccia AJ,Hahn GM,Saad AH

更新日期：1993-08-01 00:00:00

abstract：:Nucleotide receptors signaling affects cell proliferation, with possible implications on tumorigenic processes. However, molecular targets and action mechanisms of the extracellular nucleotides are still poorly elucidated. We have previously shown in ARO cells that APE1/Ref-1, a transcriptional coactivator responsible...

journal_title：Journal of cellular physiology

authors： Pines A,Bivi N,Vascotto C,Romanello M,D'Ambrosio C,Scaloni A,Damante G,Morisi R,Filetti S,Ferretti E,Quadrifoglio F,Tell G

更新日期：2006-10-01 00:00:00

abstract：:A method, based on the differing capacities of cells to adhere to a column of polyester fibres, has been described for separating human bone marrow cells into a nonadherent and an adherent fraction. The effect of this cell separation procedure on colony formation by erythroid progenitor cells was investigated. In cont...

journal_title：Journal of cellular physiology

authors： Aye MT

更新日期：1977-04-01 00:00:00

abstract：:As a natural metabolite of limonoids from Dictamnus dasycarpus, fraxinellone has been reported to be neuroprotective and anti-inflammatory. However, its influence on cellular metabolism remains largely unknown. In the present study, we investigated the effect of fraxinellone on cellular senescence-induced by oxidative...

journal_title：Journal of cellular physiology

authors： Han X,Chen H,Zhou J,Tai H,Gong H,Wang X,Huang N,Qin J,Fang T,Wang F,Xiao H

更新日期：2018-05-01 00:00:00

abstract：:Two transport systems for neutral amino acids have been characterised in LLC-PK, cells. The first, which transports alanine in a sodium-dependent manner, also mediates alanine exchange and is perferentially inhibited by serine, cysteine, and alpha-amino-n-butyric acid. This system resembles the ASC system in Ehrlich a...

journal_title：Journal of cellular physiology

authors： Sepúlveda FV,Pearson JD

更新日期：1982-08-01 00:00:00

abstract：:In certain epithelial tissues, activation of transient receptor potential (TRP) vanilloid subtype 1 (TRPV1) by noxious stimuli induces pro-inflammatory cytokine release, which helps to mitigate the challenge. While the corneal epithelium elicits such responses to a variety of challenges, it remains unknown whether TRP...

journal_title：Journal of cellular physiology

authors： Zhang F,Yang H,Wang Z,Mergler S,Liu H,Kawakita T,Tachado SD,Pan Z,Capó-Aponte JE,Pleyer U,Koziel H,Kao WW,Reinach PS

更新日期：2007-12-01 00:00:00

abstract：:Ascorbic acid induces apoptosis, autophagy, and necrotic cell death in cancer cells. We investigated the mechanisms by which ascorbic acid induces death in laryngeal squamous cell carcinoma Hep2 cells. Ascorbic acid markedly reduced cell viability and induced death without caspase activation and an increase in cytochr...

journal_title：Journal of cellular physiology

authors： Baek MW,Cho HS,Kim SH,Kim WJ,Jung JY

更新日期：2017-02-01 00:00:00