Prognostic relevance of miR-137 and its liver microenvironment regulatory target gene AFM in hepatocellular carcinoma.

abstract：:Baculoviral IAP repeat containing 5 (BIRC5) gene encodes the important protein as survivin, a multifunctional protein, which is involved in cellular and molecular networks, progression of cell cycle, homeostasis, developmental morphogenesis, and apoptosis. The proximal BIRC5 promoter possesses specific binding sites f...

journal_title：Journal of cellular physiology

authors： Pahlavan Y,Kahroba H,Samadi N,Karimi A,Ansarin K,Khabbazi A

更新日期：2019-11-01 00:00:00

abstract：:T lymphocytes from aged donors function poorly, but the biochemical basis for the defect remains uncertain. We tested the hypothesis that T cells from old mice had a diminished ability to transmit extracellular signals into the cytoplasm, by measuring intracellular free calcium concentrations (Cai) in T cells stimulat...

journal_title：Journal of cellular physiology

authors： Miller RA,Jacobson B,Weil G,Simons ER

更新日期：1987-08-01 00:00:00

abstract：:Cultured bovine adrenocortical cells were previously shown to be functionally deficient in selenium and vitamin E when grown in medium supplemented with fetal bovine serum. In the present experiments, the lack of significant bioavailable amounts of selenium in the medium was demonstrated by the finding of only low lev...

journal_title：Journal of cellular physiology

authors： Hornsby PJ,Pearson DW,Autor AP,Aldern KA,Harris SE

更新日期：1985-04-01 00:00:00

abstract：:Nidogen/entactin is a Mr = 150,000 glycoprotein which is present within basement membranes in a noncovalent stable complex with laminin. We have studied the effects of nidogen/entactin complexed or not with laminin on attachment, spreading, and functions of adult rat hepatocytes in primary culture. Freshly isolated he...

journal_title：Journal of cellular physiology

authors： Levavasseur F,Mayer U,Guillouzo A,Clement B

更新日期：1994-11-01 00:00:00

abstract：:Recent studies have indicated that endoplasmic reticulum stress, the unfolded protein response activation and altered GRP78 expression can play an important role in a variety of tumors development and progression. Very recently we reported for the first time that GRP78 is increased in endometrial tumors. However, whet...

journal_title：Journal of cellular physiology

authors： Calì G,Insabato L,Conza D,Bifulco G,Parrillo L,Mirra P,Fiory F,Miele C,Raciti GA,Di Jeso B,Terrazzano G,Beguinot F,Ulianich L

更新日期：2014-10-01 00:00:00

abstract：:A key attribute of the stringent response of bacteria is the rapid inhibition of ribosomal RNA synthesis mediated by unusual nucleotides in respnse to uncharged tRNA. The question as to whether mammalian cells show a stringent response analogous to that of bacteria was critically tested by the effective rapid amino ac...

journal_title：Journal of cellular physiology

authors： Pollard JW,Lam T,Stanners CP

更新日期：1980-11-01 00:00:00

abstract：:Muc4 (also called Sialomucin complex) is a heterodimeric glycoprotein complex consisting of a peripheral O-glycosylated subunit ASGP-1 (ascites sialoglycoprotein-1) tightly but non-covalently bound to an N-glycosylated transmembrane subunit ASGP-2. Muc4/SMC can act as an intramembrane ligand for ErbB2 via an EGF-like ...

journal_title：Journal of cellular physiology

authors： Price-Schiavi SA,Andrechek E,Idris N,Li P,Rong M,Zhang J,Carothers Carraway CA,Muller WJ,Carraway KL

更新日期：2005-04-01 00:00:00

abstract：:Rat embryo fibroblasts were grown in medium containing 14C-leucine and 3H-thymidine. After a 24-hour chase in nonlabeled medium, cultures were placed in either fresh growth medium or medium containing 10-20 microgram/ml cycloheximide. Cell monolayers were processed at daily intervals for three days. Four hours prior t...

journal_title：Journal of cellular physiology

authors： Amenta JS,Sargus MJ,Baccino FM

更新日期：1978-12-01 00:00:00

abstract：:Interleukin (IL)-37 diminishes a variety of inflammatory responses through ligation to its receptor IL-1R8/Sigirr. Sigirr is a Toll like receptor/IL-1R family member. We have shown that Sigirr is not stable in response to IL-37 treatment. IL-37-induced Sigirr degradation is mediated by the ubiquitin-proteasome system,...

journal_title：Journal of cellular physiology

authors： Li L,Wei J,Suber TL,Ye Q,Miao J,Li S,Taleb SJ,Tran KC,Tamaskar AS,Zhao J,Zhao Y

更新日期：2021-01-05 00:00:00

abstract：:Chronic hyperglycemia and activation of receptor for advanced glycation end products (RAGE) are known risk factors for microvascular disease development in diabetic retinopathy. Thioredoxin-interacting protein (TXNIP), an endogenous inhibitor of antioxidant thioredoxin (TRX), plays a causative role in diabetes and its...

journal_title：Journal of cellular physiology

authors： Perrone L,Devi TS,Hosoya K,Terasaki T,Singh LP

更新日期：2009-10-01 00:00:00

abstract：:The peroxisome proliferation-activated receptor gamma (PPARgamma) is mainly expressed in the adipose tissue and integrates the control of energy, lipid, and glucose homeostasis. The present study, by means of RT-PCR, Western blot, and immunofluorescence techniques, demonstrates that human sperm express the PPARgamma. ...

journal_title：Journal of cellular physiology

authors： Aquila S,Bonofiglio D,Gentile M,Middea E,Gabriele S,Belmonte M,Catalano S,Pellegrino M,Andò S

更新日期：2006-12-01 00:00:00

abstract：:Acute myeloid leukemia (AML) is the most common type of leukemia in adults. AML cells secrete angiogenic factors to remodel vasculature and acquire chemoresistance; however, antiangiogenic drugs are often ineffective in AML treatment. Cancer cell-derived exosomes can induce angiogenesis, but their role in vascular rem...

journal_title：Journal of cellular physiology

authors： Wang B,Wang X,Hou D,Huang Q,Zhan W,Chen C,Liu J,You R,Xie J,Chen P,Huang H

更新日期：2019-07-01 00:00:00

abstract：:Reactive oxygen species (ROS) function as signaling molecules mainly by reversible oxidation of redox-sensitive target proteins. ROS can be produced in response to integrin ligation and growth factor stimulation through Rac1 and its effector protein NADPH oxidase. One of the central roles of Rac1-NADPH oxidase is acti...

journal_title：Journal of cellular physiology

authors： Flinder LI,Timofeeva OA,Rosseland CM,Wierød L,Huitfeldt HS,Skarpen E

更新日期：2011-09-01 00:00:00

abstract：:RB loss has long been recognized as the causative genetic alteration underlying retinoblastoma but it is increasingly evident that other alterations are required for the tumor to develop. Therefore, we set out to identify additional inheritable susceptibility markers and new potential preventive and therapeutic target...

journal_title：Journal of cellular physiology

authors： Indovina P,Acquaviva A,De Falco G,Rizzo V,Onnis A,Luzzi A,Giorgi F,Hadjistilianou T,Toti P,Tomei V,Pentimalli F,Carugi A,Giordano A

更新日期：2010-04-01 00:00:00

abstract：:We have modified a method (Gilles et al: Anal. Biochem., 159:109-113, 1986) for measuring cell number, that is based on the binding of crystal violet to cell nuclei and used it to assay effects of various glycosaminoglycans on growth of human lung fibroblasts. The procedure was modified by growing cells in microcultur...

journal_title：Journal of cellular physiology

authors： Westergren-Thorsson G,Onnervik PO,Fransson LA,Malmström A

更新日期：1991-06-01 00:00:00

abstract：:Deletion of p53, most common genetic alteration, is observed in human tumors and reported to lead to improve in cell radioresistance. Heavy-ion irradiation (IR) could induce p53-/- cancer cells apoptosis. However, little is known regarding the molecular mechanism in this type of cell apoptosis. The present studies hav...

journal_title：Journal of cellular physiology

authors： Xie Y,Si J,Wang YP,Li HY,Di CX,Yan JF,Ye YC,Zhang YS,Zhang H

更新日期：2018-02-01 00:00:00

abstract：:Pterostilbene (PTS), a naturally occurring stilbene, confers protection against oxidative and cytokine stress induced pancreatic β-cell apoptosis in vitro and in vivo. To provide insights into the molecular mechanism, we performed a proteomic study on the pancreas of PTS-treated diabetic mice using electrospray ioniza...

journal_title：Journal of cellular physiology

authors： Dornadula S,Thiruppathi S,Palanisamy R,Umapathy D,Suzuki T,K Mohanram R

更新日期：2019-03-01 00:00:00

abstract：:Osteosarcoma is the most common malignant primary bone tumor in children and adolescents. The clinical outcome for osteosarcoma remains discouraging despite aggressive surgery and intensive radiotherapy and chemotherapy regimens. Thus, novel therapeutic approaches are needed. Previously, we have shown that inorganic p...

journal_title：Journal of cellular physiology

authors： Spina A,Sorvillo L,Di Maiolo F,Esposito A,D'Auria R,Di Gesto D,Chiosi E,Naviglio S

更新日期：2013-01-01 00:00:00

abstract：:Cultured preadipose 3T3 cells are able to undergo a process of differentiation through which they are converted into adipose cells. Growth hormone induces this conversion in resting cultures but not in growing cultures. It was of interest to determine the period of cell sensitivity to the hormone and the timing of the...

journal_title：Journal of cellular physiology

authors： Morikawa M

更新日期：1986-08-01 00:00:00

abstract：:The Schneider membrane is the mucosa that covers the inner part of the maxillary sinus cavities. The free surface is a ciliated pseudostratified epithelium, while the deeper portion is a highly vascularized connective tissue. The stromal fraction, bordering the bony wall of the sinus, after tooth loss can exhibit incr...

journal_title：Journal of cellular physiology

authors： Graziano A,Benedetti L,Massei G,Cusella de Angelis MG,Ferrarotti F,Aimetti M

更新日期：2012-09-01 00:00:00

abstract：:Plasminogen activator inhibitor-1 (PAI-1) is known as an inhibitor of fibrinolytic system. Previous studies suggest that PAI-1 is involved in the pathogenesis of osteoporosis induced by ovariectomy, diabetes, and glucocorticoid excess in mice. However, the roles of PAI-1 in early-stage osteogenic differentiation have ...

journal_title：Journal of cellular physiology

authors： Takafuji Y,Tatsumi K,Ishida M,Kawao N,Okada K,Matsuo O,Kaji H

更新日期：2019-06-01 00:00:00

abstract：:We have compared the biological and biochemical properties of recombinant PDGF AA, AB, and BB using three types of fibroblastic cells: NIH/3T3, human skin fibroblast, and fetal bovine aortic smooth muscle. PDGF binding, receptor autophosphorylation, phosphatidyl inositol hydrolysis, as well as chemotactic and mitogeni...

journal_title：Journal of cellular physiology

authors： Grotendorst GR,Igarashi A,Larson R,Soma Y,Charette M

更新日期：1991-11-01 00:00:00

abstract：:Circular RNAs (circRNAs) have spurred considerable interest in numerous tumors. We aimed to investigate the clinical, prognostic, and diagnostic roles of circRNAs in human lung cancer. We systematically searched PubMed, Web of Science, EMBASE, Scopus, CBM, and the Cochrane Library databases up to July 24, 2018. Eligib...

journal_title：Journal of cellular physiology

authors： Huang X,Zhang W,Shao Z

更新日期：2019-08-01 00:00:00

abstract：:This study investigated whether brain-derived neurotrophic factor (BDNF) regulates the L-glutamate/L-aspartate transporter (GLAST) and glutamine synthetase (GS) in mouse retinal Müller cells (RMCs) under normal and hypoxic conditions. Mouse RMCs were treated with recombinant human BDNF (50, 75, 100, 125, or 150  ng/ml...

journal_title：Journal of cellular physiology

authors： Dai M,Xia XB,Xiong SQ

更新日期：2012-02-01 00:00:00

abstract：:Endothelial cell-derived growth factor (ECDGF) is a soluble mitogen secreted in vitro by bovine aortic endothelium. ECDGF is a mixture of at least two distinct heat-stable and trypsin-sensitive mitogens. Large amounts of mitogenic activity were found in lysates prepared from cultured endothelial cells. Other nonmitoge...

journal_title：Journal of cellular physiology

authors： Gajdusek CM,Schwartz SM

更新日期：1984-11-01 00:00:00

abstract：:We performed a network meta-analysis (NMA) to compare the short- and long-term efficacy of Gemcitabine, Gemcitabine + S-1 (tegafur), Gemcitabine + nab-paclitaxel, Gemcitabine + Capecitabine, Gemcitabine + Cisplatin, FOLFIRINOX (oxaliplatin + irinotecan + fluorouracil + leucovorin), Gemcitabine + oxaliplatin, Gemcitabi...

journal_title：Journal of cellular physiology

authors： Zhang SH,Liu GF,Li XF,Liu L,Yu SN

更新日期：2018-04-01 00:00:00

abstract：:The members of the tumor necrosis factor (TNF) family play pivotal roles in the regulation of the immune system. LIGHT is a type II transmembrane protein belonging to the TNF family that was originally identified as a weak inducer of apoptosis. This cytokine has been extensively studied for its role in T cell regulati...

journal_title：Journal of cellular physiology

authors： Zou GM,Hu WY

更新日期：2005-12-01 00:00:00

abstract：:Transforming growth factor beta type 1 (TGF-beta 1) was reacted with NHS-biotin to yield a derivative of TGF-beta 1 which was biotinylated on lysine residues. The biotinylated form of TGF-beta 1 was separated from the unreacted material by reverse phase chromatography. In three separate bioassays, the derivatized pept...

journal_title：Journal of cellular physiology

authors： Newman W,Beall LD,Bertolini DR,Cone JL

更新日期：1989-10-01 00:00:00

abstract：:Colorectal cancer (CRC) is the third most common cancer and a leading cause of cancer-related death worldwide. About 1.8 million new cases were reported in 2018. Accordingly, there is an urgent need for development of effective strategies to lower the mortality and morbidity originated from this malignancy. MicroRNAs ...

journal_title：Journal of cellular physiology

authors： Anvarnia A,Mohaddes-Gharamaleki F,Asadi M,Akbari M,Yousefi B,Shanehbandi D

更新日期：2019-12-01 00:00:00

abstract：:Activated hepatic stellate cells promote hepatocellular carcinoma (HCC) progression. Hepatic stellate cells play a key role in retinoid metabolism, and activation of stellate cells increases retinoic acid (RA) in the liver. However, the role of RA in HCC proliferation remains unclear. We aimed to analyse the mechanism...

journal_title：Journal of cellular physiology

authors： Lin HH,Peng YJ,Tsai MJ,Wu YY,Tsai TN,Huang HH,Shih YL,Chang WK,Hsieh TY

更新日期：2020-02-01 00:00:00